JP4887305B2 - Hivの治療に有用な化合物 - Google Patents

Hivの治療に有用な化合物 Download PDF

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Publication number
JP4887305B2
JP4887305B2 JP2007548823A JP2007548823A JP4887305B2 JP 4887305 B2 JP4887305 B2 JP 4887305B2 JP 2007548823 A JP2007548823 A JP 2007548823A JP 2007548823 A JP2007548823 A JP 2007548823A JP 4887305 B2 JP4887305 B2 JP 4887305B2
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JP
Japan
Prior art keywords
dideoxy
use according
hiv
mutation
compound
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Expired - Fee Related
Application number
JP2007548823A
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English (en)
Japanese (ja)
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JP2008526713A5 (enExample
JP2008526713A (ja
Inventor
シャオ−ション・ジョウ
ホン・チャン
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Medivir AB
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Medivir AB
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Publication date
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Priority claimed from PCT/EP2005/057196 external-priority patent/WO2006070004A1/en
Publication of JP2008526713A publication Critical patent/JP2008526713A/ja
Publication of JP2008526713A5 publication Critical patent/JP2008526713A5/ja
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Publication of JP4887305B2 publication Critical patent/JP4887305B2/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2007548823A 2004-12-30 2005-12-28 Hivの治療に有用な化合物 Expired - Fee Related JP4887305B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US71453604P 2004-12-30 2004-12-30
US60/714,536 2004-12-30
EP05100063.6 2005-01-06
EP05100063A EP1679076A1 (en) 2005-01-06 2005-01-06 Compounds useful in the treatment of HIV
PCT/EP2005/057196 WO2006070004A1 (en) 2004-12-30 2005-12-28 Compounds useful in the treatment of hiv

Publications (3)

Publication Number Publication Date
JP2008526713A JP2008526713A (ja) 2008-07-24
JP2008526713A5 JP2008526713A5 (enExample) 2009-04-09
JP4887305B2 true JP4887305B2 (ja) 2012-02-29

Family

ID=34938491

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007548823A Expired - Fee Related JP4887305B2 (ja) 2004-12-30 2005-12-28 Hivの治療に有用な化合物

Country Status (2)

Country Link
EP (1) EP1679076A1 (enExample)
JP (1) JP4887305B2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10457627B2 (en) * 2015-09-23 2019-10-29 Xw Laboratories Inc. Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof
JP7483890B2 (ja) 2019-12-20 2024-05-15 エックスダブリューファーマ リミテッド 4-バリルオキシ酪酸の合成方法
EP4167966A1 (en) 2020-06-18 2023-04-26 XWPharma Ltd. Pharmaceutical granulations of water-soluble active pharmaceutical ingredients
CN115038432B (zh) 2020-06-18 2023-12-26 凯瑞康宁生物工程(武汉)有限公司 水溶性活性药物成分的控制释放制粒
WO2022020621A1 (en) 2020-07-24 2022-01-27 XWPharma Ltd. Pharmaceutical compositions and pharmacokinetics of a gamma-hydroxybutyric acid derivative
KR20230058151A (ko) 2020-10-05 2023-05-02 엑스더블유파마 리미티드 감마-하이드록시부티르산 유도체의 변형된 방출 조성물
EP4588471A3 (en) 2021-03-19 2025-09-24 XWPharma Ltd. Pharmacokinetics of combined release formulations of a gamma-hydroxybutyric acid derivative

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU697612B2 (en) * 1994-05-31 1998-10-15 Medivir Ab Post exposure prevention of HIV

Also Published As

Publication number Publication date
JP2008526713A (ja) 2008-07-24
EP1679076A1 (en) 2006-07-12

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