JP4719872B2 - Photopolymerization type denture base mucosa surface treatment material, denture base mucosa surface treatment method using the same, and denture base production method - Google Patents

Description

  The present invention relates to a dental photopolymerization denture base mucosa surface treatment material, a denture base mucosa surface treatment method using the same, and a denture base manufacturing method.

  In general, the mucous membrane that supports elderly dentures with dentures, even if a denture with excellent compatibility is attached, the mucosa of the alveolar ridge mucosa thins as age increases, making it difficult to withstand occlusal pressure, and pain and inflammation during occlusion Is likely to occur. For such patients, pain and inflammation at the time of occlusion often do not heal even if compatibility is improved with a hard lining material. Therefore, a method using a soft lining material or a tissue conditioner on the denture base mucosa is used for the purpose of bearing the occlusal pressure of the denture base in as wide an area as possible and avoiding concentrated concentration.

  As a soft denture base lining material for the purpose of pain relief at the time of occlusion, silicone-based, acrylic-based, fluoro-based, and olefin-based materials are used, and as raw materials, JP-A-2003-040723. No. (hereinafter referred to as Patent Document 1), Japanese Patent Application Laid-Open No. 2002-060311 (hereinafter referred to as Patent Document 2), Japanese Patent Application Laid-Open No. 10-245313 (hereinafter referred to as Patent Document 3), Japanese Patent Application Laid-Open No. 10-226613 (hereinafter referred to as Patent). Reference 4), Japanese Patent Application Laid-Open No. 08-291017 (hereinafter referred to as Patent Document 5), and compositions of soft lining materials for denture bases (Claims 1 to 4 of Patent Document 1, Claims 1 to 2 of Patent Document 2) There are descriptions in claims 1 and 2 of patent document 3, claim 1 of patent document 4, and claim 1) of patent document 5, but each has advantages and disadvantages, and clinically satisfactory materials have not been obtained. .

  As a silicone-based denture base soft lining material, an addition polymerization type room temperature polymerization type silicone is mainly used. This material is backed by mixing two pastes, a base and a catalyst, at the time of use, placing the mixture on the mucosal surface of the denture base, setting it in the patient's mouth and allowing it to harden. In this case, the mixing of the two types of pastes is usually carried out by automatic kneading with a dispenser, so that a homogeneous material can be obtained with less mixing of bubbles as in hand kneading.

  However, since the silicone-based lining material is not chemically bonded to the acrylic denture base resin, it is necessary to use an adhesive. However, it has been pointed out that this adhesive is peeled off at the interface with the denture base during use, which is not sufficient in terms of durability. In addition, silicone-based lining materials do not adhere to once cured materials when it is desired to add new materials, making them virtually impossible to re-correct, which is a major clinical disadvantage. ing.

  On the other hand, the acrylic lining material is of the same type as the denture base resin, so it not only chemically bonds to the denture base resin, but also adheres firmly even if you want to add new materials. Therefore, the main feature is that it can be corrected. This acrylic lining material is used by mixing a monomer and a polymer and gelling, and there are two types, a type that uses alcohol as a plasticizer and a type that polymerizes and cures at room temperature.

  In the type using alcohol as a plasticizer, alcohol is gradually eluted during use in the oral cavity, so that it hardens from the surface and the material deteriorates. Moreover, since there are many air bubbles at the time of mixing, it is easy to generate | occur | produce contamination with food and drink etc., The use is limited to a temporary thing. On the other hand, a low-molecular weight monomer is used for the room temperature curable backing material. This monomer is polymerized by polymerization, and has elasticity at the oral temperature. Although the polymer is unlikely to elute monomers during use like alcohol, the degree of polymerization immediately after curing is low, and when used over a relatively long period of time, material deterioration is observed.

  JP-A-2002-119523 (hereinafter referred to as Patent Document 6) discloses a composition and a method (claims of Patent Document 6) for a raw material of a photopolymerization type soft backing material obtained by improving the room temperature curable acrylic backing material. 1-4). In this case, the soft lining material undergoes a photopolymerization reaction due to light irradiation and changes to a viscoelastic state in the final polymerization stage, so that the surface becomes dirty like a conventional soft material even after long-term use. The durability is dramatically improved. However, there is no change in the technique of attaching the soft lining material to the once completed denture base. The denture base is buried in the plaster model again, the soft lining material is filled, photopolymerized, and the plaster is removed. This requires extra work time.

  On the other hand, a tissue conditioner may be used to disperse the occlusal pressure in the same manner and improve the feeling of denture use. As a tissue conditioner, a silicone-based or acrylic-based material is used, and as a raw material, most of the materials are close to the composition of a soft denture base lining material, and the properties are similar. JP-A-2001-46404 (hereinafter referred to as Patent Document 7) has a description of a denture and a manufacturing method thereof (Claims 1 to 4 of Patent Document 7), but uses a silicone system and is the same as a soft lining material. Since the tissue conditioner is bonded to the denture base via an adhesive, there is a problem in durability.

JP 2003-040723 A JP 2002-060311 A Japanese Patent Laid-Open No. 10-245313 Japanese Patent Laid-Open No. 10-226613 JP-A-8-291017 JP 2002-119523 A JP 2001-46404 A

  The present invention solves the problems of denture base soft backing materials and tissue conditioners, has good adhesion to the oral mucosal surface, a good feeling of wearing, and can be easily performed in the process of manufacturing a denture base resin. Photopolymerization type that can adhere to the mucosal surface of heat-polymerization type, chemical polymerization-type and photopolymerization-type denture base resins, completes the polymerization reaction in a short time, and can obtain a smooth denture base surface without bubbles. An object of the present invention is to provide a denture base mucosa treatment material, a denture base mucosa treatment method and a denture base production method using the same.

  The inventor made a photopolymerization type denture base mucosal surface treatment material comprising a photopolymerizable oligomer chemically bonded to a denture base resin or a viscous solution obtained by mixing a photopolymerizable oligomer and a methacrylate ester, Solved the problem. In addition, this photopolymerization type denture base mucosa surface treatment material is applied with a brush onto a plaster model that has previously impressed the inside of the oral cavity, molded into a desired shape, photopolymerized, and filled with a denture base resin. It was found that a denture basement mucosa surface excellent in durability and durability can be obtained.

  That is, the photopolymerization denture base mucosal surface treatment material of the present invention comprises radically polymerizable urethane-based oligomers 49.8 to 99.6 wt%, methacrylic acid esters 0 to 49.8 wt%, methacrylic acid ester polymers or methacrylic acid. It is characterized by blending 0 to 49.8 wt% of an ester copolymer, 0.2 to 2 wt% of a photosensitizer and 0.2 to 2 wt% of a reducing agent.

  The radically polymerizable urethane-based oligomer used in the photopolymerization denture base mucosal surface treatment material of the present invention has an oligomerized photopolymerization activity, that is, a photopolymerizable oligomer, and as the urethane-based oligomer, Examples thereof include urethane acrylate and urethane methacrylate. When the said urethane type oligomer is urethane acrylate, what shows a viscosity of 1000-30000 mPa * s and what adjusted the viscosity by adding 0-30 wt% of polyfunctional monomers are included. Moreover, when the said urethane-type oligomer is urethane methacrylate, what shows a viscosity of 1000-30000 mPa * s and what adjusted the viscosity by adding 0-30 wt% of polyfunctional monomers are included. Here, as the polyfunctional monomer, ethylene glycol dimethacrylate, triethylene glycol dimethacrylate, butanediol dimethacrylate, 2,2-bis- (4-methacryloxyethoxyphenyl) propane, 2,2-bis- ( 4-methacryloxyphenyl) propane.

  The content of the radically polymerizable urethane oligomer in the photopolymerization denture base mucosa treatment material of the present invention is in the range of 49.8 to 99.6 wt%. When the urethane oligomer content is less than 49.8 wt%, it is difficult to maintain a certain shape on the plaster model.

  The photosensitizer used in the photopolymerization type denture base mucosa surface treatment material of the present invention is activated by visible light with the help of a reducing agent to generate free radicals, thereby causing polymerization. Examples include camphorquinone, benzyl, diacetyl, anthraquinone, and benzoin methyl ether.

  The content of the photosensitizer in the photopolymerization denture base mucosal surface treatment material of the present invention is in the range of 0.2 to 2 wt%. If the photosensitizer content is less than 0.2 wt%, the photopolymerization denture base mucosa treatment material cannot be sufficiently photopolymerized, while if the photosensitizer content exceeds 2 wt%. It not only works as a plasticizer and lowers physical properties, but also colors the mucosal surface treatment material.

  The reducing agent used in the photopolymerization denture base mucosa treatment material of the present invention helps to activate the photosensitizer, such as N, N-dimethylaminoethyl methacrylate, triethanolamine, dimethylaminobenzoate. Examples thereof include acid derivatives and thiobarbituric acid derivatives.

  The content of the reducing agent in the photopolymerization denture base mucosa treatment material of the present invention is in the range of 0.2 to 2 wt%. If the content of the reducing agent is less than 0.2 wt%, the activation of the photosensitizer cannot be sufficiently helped. On the other hand, if the content of the reducing agent exceeds 2 wt%, it functions as a plasticizer, and the physical properties are reduced. Reduce.

  The photopolymerization denture base mucosal surface treatment material of the present invention includes a methacrylic acid ester, a methacrylic acid ester polymer, or a methacrylic acid ester copolymer in addition to the radically polymerizable urethane oligomer, photosensitizer, and reducing agent. A coalescence can be blended. Here, the content of the methacrylic acid ester in the photopolymerization denture base mucosa treatment material of the present invention is in the range of 0 to 49.8 wt%, and the content of the methacrylic acid ester polymer or the methacrylic acid ester copolymer. The rate ranges from 0 to 49.8 wt%. Here, examples of the methacrylic acid ester include methyl methacrylate, ethyl methacrylate, butyl methacrylate, and the like. By homopolymerizing or copolymerizing the monomer, a methacrylic acid ester polymer or a methacrylic acid ester copolymer is obtained. can get.

  The photopolymerization type denture base mucosa surface treatment material of the present invention preferably undergoes a photopolymerization reaction when irradiated with visible light, and changes from a viscous state to an elastic state. Here, the photopolymerization denture base mucosal surface treatment material of the present invention preferably has a modulus of elasticity after the photopolymerization reaction in the range of 0.2 to 20 MPa, and more preferably in the range of 5 to 20 MPa. If the elastic modulus after the photopolymerization reaction is within this range, the elastic modulus is almost equal to the elastic modulus of the human oral mucosa.

  The photopolymerization denture base mucosal surface treatment material of the present invention is obtained by, for example, defoaming urethane acrylate or urethane methacrylate, to which a photosensitizer and a reducing agent are added, by heating and rotating with a dedicated mixer to form a viscous solution. Can be manufactured.

  The photopolymerization type denture base mucosa surface treatment material of the present invention can be used as a single layer or laminated, and when laminated, the elastic modulus after the photopolymerization reaction of each layer is preferably different.

  The denture base manufacturing method of the present invention is a method of taking out the photopolymerization denture base mucosa surface treatment material from a container with a brush, applying an appropriate amount to a target position in the oral cavity on a gypsum model replicating the patient's oral cavity, And polymerizing by adding a chemical polymerization type, heat polymerization type or photopolymerization type denture base resin. Here, it is preferable that the container for storing the photopolymerization denture base mucosa treatment material is light-shielded.

  In the denture base manufacturing method of the present invention, the denture base mucosa surface treatment material portion may be laminated by applying the photopolymerization denture base material having a different elastic modulus after curing several times. . In this case, the surface of the denture base mucosa surface treatment material portion can be softened and the inside can be hardened to provide so-called functional gradient performance.

  As described above, according to the denture obtained using the photopolymerization denture base mucosa surface treatment material of the present invention, the soft thin film is attached to the denture base surface in contact with the oral mucosa, so that the soft thin film It adheres well to the oral mucosa, and the soft thin film exhibits moderate elasticity, and the occlusal pressure can be evenly distributed throughout the oral mucosa via the soft thin film, and is therefore relatively strong. Occlusal pressure can be exerted.

  First, a photopolymerization denture base mucosa treatment material with low elasticity after curing is applied and polymerized, and then a photopolymerization denture base material with high elasticity after cure is applied and polymerized. By doing so, since the surface layer portion can be imparted with the property of becoming harder toward the inside, a denture base having an excellent wearing feeling can be produced.

  And since the photopolymerization type denture base mucosa surface treatment material of the present invention uses a urethane oligomer of the same system as the denture base resin as a component, the photopolymerization type denture base material for denture base and denture base The resin is chemically bonded and the durability is dramatically improved. Furthermore, since this urethane-based oligomer is sufficiently polymerized by photopolymerization, the photopolymerization denture base mucosa treatment material after polymerization maintains sufficient durability for a long period of time as much as the denture base resin. it can.

  In addition, according to the method for manufacturing a denture base of the present invention, first, a viscous photopolymerization denture base mucosal surface treatment material is applied thinly on a gypsum model surface impressed by the oral cavity so as to fit the mucosal surface of the patient. It is possible to easily and accurately form a photopolymerization type denture base mucosa surface treatment material film having a thickness and shape suitable for the patient. For photopolymerization, heat-polymerized, chemical-polymerized and photopolymerized denture base resins can be used as denture base resins. Moreover, since the photopolymerization process of this photopolymerization type denture base mucosa surface treatment material can be performed in the process of the conventional denture base resin manufacture, the denture base resin can be manufactured very easily.

  Furthermore, when the photopolymerization type denture base mucosa surface treatment material of the present invention is attached to the denture base, the working time is greatly shortened, and the photopolymerization type denture base mucosa surface treatment material is a part of the denture base resin. Resin for denture base because it functions clinically, so even if it is used for a long time, the surface is less likely to become dirty like conventional soft lining materials, and the durability has been dramatically improved. Useful for patients using.

  A method for producing a denture base using the photopolymerization type denture base mucosa surface treatment material of the present invention will be specifically described. First, an impression is taken from within the patient's mouth, and a replicated plaster model is produced. Artificial teeth are arranged on the plaster model to produce a wax denture. An upper jaw model is placed at the bottom of the polymerization flask, and gypsum is poured into the gap. After the gypsum has hardened, a separating agent is applied to the surface, and the gypsum is poured into the top of the polymerization flask. After the gypsum has hardened, the polymerization flask is divided and poured to complete the maxillary palatal lingual model and the palatal mucosa model.

  A photopolymerization denture base treatment material is applied to a desired location on the completed maxilla palate mucosa side model with a brush, irradiated with light, and polymerized. After the polymerization is completed, the upper part of the polymerization flask is returned to the lower part of the polymerization flask, and the denture base resin is filled into the gap according to the method. Thereafter, the denture base resin is polymerized, and after cooling at room temperature, the denture base is taken out of the plaster model of the polymerization flask and the surface is polished. FIG. 1 is a completed partial denture, and FIG. 2 is a completed full denture. In the figure, 11 and 21 indicate artificial teeth, 13 and 23 indicate denture base resins, and 15 and 25 indicate photopolymerization denture base mucosal surface treatment materials.

  Hereinafter, the present invention will be described in more detail with reference to examples. However, the present invention is not limited to the following examples.

(Preparation of photopolymerization denture base mucosal surface treatment material)
1 wt% of camphorquinone and 1 wt% of N, N-dimethylaminoethyl methacrylate were added to 90 wt% of urethane methacrylate mixed with 10 wt% of ethyl methacrylate, and used as a photopolymerization denture base mucosal surface treatment material.

[Example 1]
The photopolymerization denture base mucosa treatment material taken out from the light-shielding bottle was applied onto an acrylic plate with a brush and smoothed, and then photopolymerized with a light irradiator for 5 minutes. On top of that, a commercially available denture base resin was filled using a Teflon (registered trademark) mold so as to have an inner diameter of 10 mm and polymerized. After removing the Teflon (registered trademark) mold, the tensile strength of the test piece was measured. The results are shown in Table 1. From Table 1, it can be seen that the denture base resin is sufficiently bonded to the photopolymerization denture base mucosa surface treatment material.

[Example 2]
The photopolymerization type denture base mucosa surface treatment material taken out from the light shielding bottle was applied onto a Teflon (registered trademark) plate with a brush and smoothed, and then photopolymerized for 5 minutes with a light irradiator. The polymer was finely pulverized and immersed in tetrahydrofuran for 2 days to elute residual monomers. The eluted solution was subjected to high performance liquid chromatography to detect monomers. The results are shown in Table 2 in comparison with the dental polymer. From Table 2, it can be seen that the amount of residual monomer is similar to that of the denture base resin, and that the photopolymerization denture base mucosa surface treatment material is sufficiently polymerized.

  In Table 2, UDMA represents urethane dimethacrylate, MMA represents methyl methacrylate, and Bis-GMA represents bisphenol A glycidyl methacrylate.

Example 3
The photopolymerization denture base mucosa treatment material taken out from the light-shielding bottle was applied onto an acrylic plate with a brush and smoothed, and then photopolymerized with a light irradiator for 5 minutes. The hardness of the surface of the obtained polymer was measured with a Shore A hardness meter. The surface hardness is closely related to the elastic modulus and is an index of “hard” and “soft”. The results are shown in Table 3. From Table 3, the photopolymerization denture base mucosa surface treatment of the present invention has a hardness range similar to each of the popular soft lining materials, and includes commonly used acrylic and silicone values. This shows that it can be used clinically enough.

It is a figure of an example of the partial denture completed using the photopolymerization type denture base mucosa surface treatment material of this invention. It is a figure of the example of the complete denture completed using the photopolymerization type denture base mucosa surface treatment material of this invention.

Explanation of symbols

11 Artificial Teeth 13 Denture Base Resin 15 Photopolymerization Denture Base Mucosa Surface Treatment Material 21 Artificial Teeth 23 Denture Base Resin 25 Photopolymerization Denture Base Mucosal Surface Treatment Material

Claims (6)

  Radical-polymerizable urethane oligomer 49.8 to 99.6 wt%, methacrylic acid ester 0 to 49.8 wt%, methacrylic acid ester polymer or methacrylic acid ester copolymer 0 to 49.8 wt% and photosensitizer 0 A photopolymerization denture base material for treating mucosal surface of a denture, characterized by comprising 0.2 to 2 wt% and a reducing agent 0.2 to 2 wt%.   The photopolymerization denture base mucosa surface treatment material according to claim 1, wherein a photopolymerization reaction occurs by irradiation with visible light and changes from a viscous state to an elastic state.   The elastic material after photopolymerization reaction is in the range of 0.2 to 20 MPa, The photopolymerization type denture base mucosa surface treatment material according to claim 1 or 2.   A method for treating a denture basement mucosal surface, wherein the photopolymerization type denture basement mucosa surface treatment material according to any one of claims 1 to 3 is used as a single layer or laminated.   The method for treating a denture basement mucosal surface according to claim 4, wherein the elastic modulus after the photopolymerization reaction of the laminated photopolymerization type denture basement mucosa surface treatment material is different in each layer.   The photopolymerization denture base mucosa treatment material according to any one of claims 1 to 3 is taken out of a container with a brush, and an appropriate amount is applied to a target position in the oral cavity on a plaster model in which the patient's oral cavity is replicated. A method for producing a denture base, characterized in that a chemical polymerization type, heat polymerization type or photopolymerization type denture base resin is added and polymerized.

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