JP4641165B2 - Detergent composition for local cleaning equipment - Google Patents

Description

  The present invention relates to a low-irritant cleaning composition that can be used for toilet seats with a local cleaning device and cleaning water for a portable local cleaning device.

  In recent years, interest in hygiene and health has increased, and toilet seats with local cleaning devices that can clean local areas in toilets have become widespread. This toilet seat with a local cleaning device is designed to inject water or hot water into the local area with a cleaning nozzle and use it for cleaning after using the toilet. It is very convenient for those who have illness, and portable cleaning devices are also popular for use outdoors.

  However, current toilet seats with local cleaning devices and portable cleaning devices are designed to be cleaned only with tap water, and in order to obtain a strong cleaning power, there was no choice but to inject more water. . However, many people feel uncomfortable with strong water currents, and people with illnesses such as hemorrhoids may exacerbate their symptoms. Therefore, it is known to wash the local area with a washing water with a surfactant such as an alkyl sulfate ester salt and having enhanced detergency (for example, see Patent Document 1).

  However, surfactants such as alkyl sulfate ester salts used in Patent Document 1 are known to have high skin irritation, and when wash water to which such surfactants are added is used, It may not be safe for delicate local areas. Furthermore, such anionic surfactants have excellent foaming and foam holding properties, and some people feel uncomfortable due to foam adhering to the local area or foaming in the stored water. In addition, when carried in a portable cleaning device, the cleaning liquid bubbles due to vibration, and it may be difficult to pump out the cleaning liquid with a pump.

JP 2004-59705 A

  Therefore, the problem to be solved by the present invention is to provide a cleaning composition that is hygienic and less irritating to the human body in washing water of a toilet seat with a local washing device, as compared with washing with water alone. There is.

  Therefore, the present inventors have found a cleaning composition that exhibits a high cleaning ability and is less irritating to the human body by using a specific surfactant, and has reached the present invention.

That is, the present invention represents the water-soluble or water-dispersible polyalkylene glycol represented by the general formulas (1) and (2) as the component (A) and the general formula (3) as the component (B). The water-soluble or water-dispersible polyalkylene glycol alkyl (or alkenyl) ether, wherein (B) component is 0.01 to 10 parts by mass with respect to 1 part by mass of component (A) , and component (A) and (B) the total content of the component characterized in that it comprises at 0.01 to 3 wt%, a private part washing device for cleaning compositions.

  The cleaning composition for a local cleaning apparatus of the present invention has a large cleaning effect on a delicate local part and is less irritating.

  Examples of the component (A) of the present invention include polyethylene glycol, random polymers and block polymers of polyethylene glycol and polypropylene glycol, alkylene oxide adducts of glycol compounds (divalent alcohols), water-soluble or water-dispersible low Examples include molecular polypropylene glycol. Among these compounds, a block polymer of polyethylene glycol and polypropylene glycol as represented by the following general formulas (1) and (2) is particularly preferable.

（式中、ｐおよびｐ'はそれぞれ独立した５〜２５０である数を表し、ｑは１５〜１５０である数を表し、分子中のポリエチレンオキシドの総分子量が、全体の分子量の１０質量％以上である。）

(In the formula, p and p ′ each independently represent a number of 5 to 250, q represents a number of 15 to 150, and the total molecular weight of polyethylene oxide in the molecule is 10% by mass or more of the total molecular weight. .)

（式中、ｒおよびｒ'はそれぞれ独立した８〜８０である数を表し、ｓは１０〜５００である数を表し、分子中のポリエチレンオキシドの総分子量が、全体の分子量の１０質量％以上である。）

(In the formula, r and r ′ each independently represent a number of 8 to 80, s represents a number of 10 to 500, and the total molecular weight of polyethylene oxide in the molecule is 10% by mass or more of the total molecular weight. .)

The component (A) represented by the general formula (1) can be obtained by adding ethylene oxide to polypropylene glycol represented by HO— (C ₃ H ₆ O) _q —H. q shows the average addition mole number of propylene oxide, is a number of 15-150, Preferably it is a number of 20-75, More preferably, it is a number of 25-60. When q is less than 15, the performance as a cleaning agent may not be sufficiently exhibited, and when q exceeds 150, the solubility or dispersibility in water may deteriorate. Further, when q is larger than 75, it is necessary to use a special catalyst or repeat purification for production, and q is preferably 75 or less in view of economical aspect.

p and p ′ represent the average number of moles of ethylene oxide added to the two hydroxyl groups of polypropylene glycol represented by HO— (C ₃ H ₆ O) _q —H, and each represents an independent number of 5 to 250. is there. When the average added mole number of ethylene oxide is less than 5, the performance as a cleaning agent may not be sufficiently exerted, and when it exceeds 250, the melting point increases, and storage stability may be adversely affected. The total molecular weight of ethylene oxide can be determined from the sum of p and p ′. The total molecular weight of ethylene oxide in the total molecular weight of the block copolymer represented by the general formula (1) must be added so as to be 10% by mass or more, more preferably 20 to 95% by mass, and still more preferably. Is 40 to 95% by mass, most preferably 50 to 90% by mass. When the proportion of ethylene oxide is less than 10% by mass, it may precipitate without dissolving or dispersing in water, and may clog piping and the like.

The component (A) represented by the general formula (2) can be obtained by adding propylene oxide to polyethylene glycol represented by HO— (C ₂ H ₄ O) _s —H. s is a number of 10 to 500, preferably 15 to 450, and more preferably 20 to 400. When s exceeds 500, the melting point increases, and storage stability may be adversely affected. When s is less than 10, the solubility or dispersibility in water may deteriorate, and piping or the like may be clogged.

r and r ′ represent the average number of moles of propylene oxide added to the two hydroxyl groups of polyethylene glycol represented by HO— (C ₂ H ₄ O) _s —H, each being an independent number of 8-80. It is. When the average added mole number of propylene oxide is less than 8, the performance as a cleaning agent may not be sufficiently exerted, and when it exceeds 80, it may precipitate without being dissolved or dispersed in water and clog piping and the like. Although the total molecular weight of ethylene oxide is determined from the number of s, the total molecular weight of ethylene oxide in the total molecular weight of the block copolymer represented by the general formula (2) is 10% by mass or more. More preferably, it is 20-95 mass%, More preferably, it is 40-95 mass%, Most preferably, it is 50-90 mass%. When the proportion of ethylene oxide is less than 10% by mass, it may precipitate without dissolving or dispersing in water, and may clog piping and the like.

Examples of the component (B) of the present invention include monohydric alcohol derivatives such as polyalkylene glycol monoalkyl (alkenyl) ether and polyalkylene glycol dialkyl (alkenyl) ether; polyalkylene glycol glyceryl ether, polyalkylene glycol trimethylol propane ether And polyhydric alcohol derivatives such as polyalkylene glycol pentamonoerythritol ether, tetrahydric alcohol derivatives such as polyalkylene glycol sorbitan ether, and the like, and polyalkylene glycol (mono and polyvalent) alkyl (alkenyl) ethers. Among these compounds, polyalkylene glycol monoalkyl (alkenyl) ethers represented by the following general formula (3) are particularly preferable.

（Ｒは炭素数１〜３０の脂肪族炭化水素基であり、Ａは炭素数２〜４のアルキレン基であり、ｎは１〜８０の数を示す）

(R is a C1-C30 aliphatic hydrocarbon group, A is a C2-C4 alkylene group, n shows the number of 1-80.)

  The component (B) represented by the general formula (3) can be obtained by adding an alkylene oxide having 2 to 4 carbon atoms to the alcohol represented by ROH. R is a linear, branched, saturated or unsaturated aliphatic hydrocarbon and is not particularly limited as long as it has 1 to 30 carbon atoms. Examples of these aliphatic hydrocarbons include methyl, ethyl, propyl, isopropyl, butyl, isobutyl, secondary butyl, tertiary butyl, pentyl, isopentyl, secondary pentyl, neopentyl, tertiary pentyl, hexyl, and secondary hexyl. , Heptyl, secondary heptyl, octyl, 2-ethylhexyl, secondary octyl, nonyl, secondary nonyl, decyl, secondary decyl, undecyl, secondary undecyl, dodecyl, secondary dodecyl, tridecyl, isotridecyl, secondary tridecyl, tetradecyl Alkyl groups such as secondary tetradecyl, hexadecyl, secondary hexadecyl, stearyl, eicosyl, docosyl, tetracosyl; vinyl, allyl, propenyl, isopropenyl, butenyl, isobutenyl, pentenyl, isopentenyl, hexenyl, hexenyl Thenyl, octenyl, nonenyl, decenyl, undecenyl, dodecenyl, tetradecenyl, alkenyl groups such as oleyl, also to remove the number 30 or more carbon atoms, may be a group obtained by removing hydroxyl groups from mixed alcohols derived from natural fats and oils. These natural fats and oils include, for example, linseed oil, eno oil, jute deer oil, olive oil, cacao butter, kapok oil, white mustard oil, sesame oil, rice bran oil, safflower oil, shea nut oil, cinnakiri oil, soybean oil, tea seed Vegetable oils such as oil, camellia oil, corn oil, rapeseed oil, palm oil, palm kernel oil, castor oil, sunflower oil, cottonseed oil, coconut oil, tree wax, peanut oil; horse fat, beef tallow, cow leg fat, cow tallow Animal fats such as pork fat, goat fat, sheep fat, milk fat, fish oil, whale oil and the like.

In General formula (3), A represents a C2-C4 alkylene group. The part (AO) _n is formed by addition polymerization of alkylene oxide, and AO is determined depending on the type of alkylene oxide to be added. More specifically, the (AO) _n portion is obtained by a method such as addition polymerization of an alkylene oxide having 2 to 4 carbon atoms such as ethylene oxide, propylene oxide, butylene oxide, tetrahydrofuran (1,4-butylene oxide) or the like. be able to.

  The average degree of polymerization n is a number from 1 to 80, but the preferred range varies depending on the carbon number of R. When R has a small number of carbon atoms, it has a function of dissolving dirt as a glycol solvent, and when R is large, it has a function of removing dirt as a surfactant. Since the two functions are different, the preferable range of the degree of polymerization of the alkylene oxide varies depending on the number of carbon atoms. When R has 1 to 4 carbon atoms, the average degree of polymerization n is preferably 1 to 40, more preferably 1 to 20, still more preferably 1 to 10, and most preferably 1 to 5. When R has 5 to 30 carbon atoms, the average degree of polymerization n is preferably 4 to 80, more preferably 6 to 60, still more preferably 8 to 40, and most preferably 8 to 20. When n is greater than 40 when R is 1 to 4 carbons, or when n is greater than 80 regardless of the carbon number of R, the effect as a glycol-based solvent and the effect as a surfactant are reduced. May fall. Further, when R is 5 to 30 carbon atoms and n is smaller than 4, it may precipitate without being dissolved or dispersed in water and clog piping and the like.

  The polymerization form of the alkylene oxide to be added is not limited, and may be homopolymerization of ethylene oxide, homopolymerization of other alkylene oxides, random copolymerization of two or more alkylene oxides, block copolymerization or random / block copolymerization.

  From the viewpoint of water solubility or water dispersibility, the proportion of ethylene oxide in the total alkylene oxide is preferably 40 mol% or more, more preferably 60 mol% or more, and still more preferably 80 when R is 7 to 20 carbon atoms. It is more than mol%, most preferably more than 90 mol%. When the ratio of ethylene oxide is less than 40 mol%, it may precipitate without being dissolved or dispersed in water and clog piping and the like. The solubility in water when R is 1 to 4 carbon atoms is dissolved or dispersed in water when n is small, regardless of the type of alkylene oxide. Therefore, when n is a number of 3 or less, any kind of alkylene oxide may be used, but ethylene oxide or propylene oxide is preferred. However, when n is larger than 3, the proportion of ethylene oxide in the total alkylene oxide is preferably 40 mol% or more, more preferably 60 mol% or more, still more preferably 80 mol% or more, and most preferably 90 mol% or more. is there. When the ratio of ethylene oxide is less than 40 mol%, it may precipitate without being dissolved or dispersed in water and clog piping and the like.

In the cleaning composition for a local cleaning device of the present invention, the total content of the component (A) and the component (B) is preferably 0.01 to 50% by mass with respect to the entire composition. When the amount is less than 0.01% by mass, the cleaning effect may not be expected. When the amount exceeds 50% by mass, the stability of the composition may deteriorate due to gelation or the like. However, when the local part is actually washed, the total of the component (A) and the component (B) is preferably washed at 0.01 to 5% by mass, more preferably 0.01 to 3% by mass, and 02-1 mass% is still more preferable. When the total concentration of the component (A) and the component (B) is high, it may be used after being diluted with water.
In the cleaning composition for a local cleaning device of the present invention, when the component (A) and the component (B) are contained, the component (B) is 0.01 to 1 part by weight of the component (A). 10 mass parts is preferable, 0.1-8 mass parts is more preferable, and 0.3-5 mass parts is still more preferable.

  The component (C) of the present invention is glycerin, diglycerin, polyglycerin, (di- or poly) glycerin ester, polyalkylene glycol ester, propylene glycol, dipropylene glycol, and these are used as a cleaning agent and / or a humectant. With the function of.

  Polyglycerol can be obtained by dehydration condensation of glycerol or a polymerized derivative of epichlorohydrin. 3-20 are preferable, as for the average degree of polymerization of polyglycerol, 3-15 are more preferable, and 3-10 are still more preferable. Even if the average degree of polymerization exceeds 20, it is functionally not changed as compared with 20 or less, and the viscosity becomes too high, which may make handling difficult. The (di- or poly) glycerin ester is obtained by esterifying glycerin, diglycerin, or the above-mentioned polyglycerin, or a mixture thereof with a fatty acid, and the fatty acid used for esterification has 6 to 6 carbon atoms. 24 fatty acids are preferable, and fatty acids obtained from natural fats and oils having 8 to 24 carbon atoms are more preferable. If the number of carbon atoms exceeds 24, the melting point of the resulting ester compound increases, and the pipes and the like may be clogged due to precipitation, etc. If the number of carbon atoms is less than 6, the function as a hydrophobic group is weak and the cleaning action is weak. There is a case.

  The polyalkylene glycol ester is obtained by esterifying a polyalkylene glycol with a fatty acid. As for the polyalkylene glycol used, the proportion of ethylene oxide in the total alkylene oxide is preferably 40 mol% or more, more preferably 60 mol% or more, still more preferably 80 mol% or more, and most preferably 90 mol% or more. When the ratio of ethylene oxide is less than 40 mol%, it may precipitate without being dissolved or dispersed in water and clog piping and the like. Moreover, the fatty acid used for esterification is preferably a fatty acid having 1 to 24 carbon atoms, more preferably a fatty acid having 6 to 24 carbon atoms, and further preferably a fatty acid obtained from natural fats and oils having 8 to 24 carbon atoms. When the number of carbon atoms exceeds 24, the melting point of the resulting ester compound increases, and piping and the like may be clogged due to problems such as precipitation.

  (C) component of this invention can be mix | blended 0.01-30 mass% with respect to the whole composition, However, When actually wash | cleaning a local part, it is used at 0.01-5 mass%. It is preferably 0.02 to 3% by mass. When the concentration of the component (C) is high, it may be used after being diluted with water. When the amount is less than 0.01% by mass, the cleaning effect and the moisturizing effect may not be expected. When the amount exceeds 30% by mass, the stability of the composition such as gelation may be deteriorated.

  Since the cleaning liquid containing the surfactant is sprayed to the local area during cleaning, bubbles may adhere around the local area, or the stored water in the toilet may be foamed. For this reason, a large amount of water is required for local rinsing, and some people may feel uncomfortable. In addition, if foaming occurs in the cleaning liquid tank in the local cleaning device, the spraying device may not work well, and it is preferable to use a surfactant with less foaming.

  In order to measure the foaming of the surfactant, it can be measured by the Ross Miles method (JIS K3362), which is a general test method. The Ross Miles method measures the height of bubbles generated when 200 ml of a sample aqueous solution having a predetermined concentration is dropped from the height of 900 mm on the liquid surface for 30 seconds under a predetermined temperature condition to obtain a foaming force. Is.

  When the foaming of the 0.1 mass% aqueous solution of the total of the component (A) and the component (B) of the present invention is measured by the Ross Miles method at 25 ° C., the foam height after 3 minutes is 100 mm or less. It is preferable. When the foaming after 3 minutes is more than 100 mm, the foam may adhere around the local area, the water stored in the toilet bowl may be foamed, or may foam in the cleaning liquid tank in the local cleaning device. In particular, a portable cleaning device is often foamed due to vibration when it is carried, so a cleaning composition with less foaming is preferred.

  In the cleaning composition for a local cleaning apparatus of the present invention, in addition to the above-described components, other optional components are usually used as necessary within the range that does not impair the effects of the present invention, considering the dilution rate. Can be blended in any amount. For example, a moisturizing agent, a chelating agent, an antibacterial agent, a deodorizing agent, a fragrance, a solvent, a drug and the like can be mentioned.

  Examples of humectants include plant extract ingredients such as aloe extract, cucumber juice, barley extract, wheat germ extract, seaweed extract, eucalyptus oil, lavender oil; glucooligos produced from soybean phospholipids, squalane, jojoba oils, and plant materials. Animal and plant derived components such as sugar, hydrolyzed collagen, hydrolyzed elastin, ceramides, amino acids and lecithins; vitamins such as vitamin A and vitamin E, urea and the like.

  Examples of chelating agents include ethylenediaminetetraacetic acid, hydroxyethylethylenediaminetriacetic acid, dihydroxyethylethylenediaminediacetic acid, propanediaminetetraacetic acid, diethylenetriaminepentaacetic acid, triethylenetetraminehexaacetic acid, nitrilotriacetic acid, hydroxy Examples include ethyliminodiacetic acids, gluconic acids, sodium malate, sodium citrate, sodium tripolyphosphate, sodium carbonate, sodium silicate, zeolite, and the like.

  Antibacterial agents include, for example, parabens such as methyl paraben and butyl paraben, quaternary ammonium salts, pyridinium compounds, glycerin fatty acid esters, glycerin alkyl ethers, glycols typified by octanediol, sodium alginate, catechins , Phenoxyethanol, salicylic acid and the like.

  Examples of the deodorizer include triclosan, trichlorocarban, diglycerin monofatty acid ester, triglycerin monofatty acid ester, alkane dicarboxylic acid and the like.

  Examples of the fragrance include natural fragrances obtained from plants and animals, synthetic fragrances such as coal tar-based, petroleum-based, acetylene-based, pinene-based, ester-based, and blended fragrances prepared by blending a plurality of fragrances. Examples of the solvent include ethanol and mineral oil.

  A drug is a component that can be expected to have a medicinal effect against local diseases and trauma. Here, local diseases and injuries include, for example, hemorrhoids such as internal hemorrhoids, external hemorrhoids, hemorrhoids, and anal fissures; perianal abscesses, local rashes and skin irritation, and perianal diseases and skin diseases Genital diseases such as bartholin adenitis, genital herpes, vulva, atrophic vulvitis, vaginitis, sexual illness; trauma such as local cuts, burns and burns. Examples of drugs for these diseases and injuries include antibiotics, antiseptics, vasoconstrictors, anti-itch agents, anti-inflammatory agents, analgesics, and herbal medicines with various effects. When general consumers use these drugs, it is preferable to use highly safe drugs such as quasi-drugs. When using these drugs in hospitals and sanatoriums, the diagnosis and prescription of doctors are recommended. In addition, pharmaceuticals can also be used.

  When the cleaning composition for a local cleaning apparatus of the present invention is actually used, it may be diluted with water by an arbitrary method or sprayed in advance to the local. Specifically, in a toilet with a local cleaning device, water or warm water containing the cleaning composition of the present invention is sprayed onto the local area and then cleaned, and then rinsed with tap water or the like. . Examples of the method of adding the cleaning composition of the present invention to a cleaning liquid and injecting the same include, for example, a method of injecting a high concentration of the cleaning composition of the present invention with water in a local cleaning apparatus, A method of injecting the diluted low-concentration detergent composition of the present invention as it is using a local cleaning device, and the detergent composition of the present invention can be obtained by using a polyether such as polyethylene glycol or polyethylene glycol stearate. When mixed with a water-soluble solid (gradual solubilizer) with a slow dissolution rate, such as esterified products such as polyethylene glycol urethanized, and gradually dissolved in a tank containing cleaning water, Since the cleaning composition of the present invention melts, a method of spraying the cleaning composition with a local cleaning device and a portable spraying device can be used to dilute the cleaning composition of the present invention with a high concentration. A method in which injection or insert previously diluted low concentration of the detergent composition of the present invention. Any method and apparatus may be used, but it is preferable to use an apparatus capable of mixing the cleaning composition of the present invention concentrated to a high concentration with water and spraying the diluted cleaning water, and can be used easily at any time. Therefore, it is more preferable to use a portable injection device. Moreover, it is preferable to wash several times to 10 times a day, and in the treatment of illness and trauma, relief of symptoms, etc., use other than at the time of discharge is also effective.

  Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited thereto.

<Protein denaturation test>
In order to evaluate skin irritation, a protein denaturation test was performed by the following method according to the method of Miyazawa et al. (Japan Cosmetic Engineers Association Journal 18 (2), 96-105 (1984)). That is, in an aqueous solution containing 0.15 mol / L sodium sulfate and 0.05 mol / L sodium phosphate as a pH 7 buffer solution, 10 mL of a solution in which 0.025% by mass of ovalbumin (manufactured by Wako Pure Chemical Industries) was dissolved, 1 mg of the product of the present invention or comparative product was mixed. Immediately after preparation of this solution and after standing at 25 ° C. for 48 hours, the protein denaturation rate was determined by quantifying the amount of ovalbumin using liquid chromatography under the following conditions. The results are shown in Tables 1 and 2.

<Conditions>
Column: manufactured by Tosoh Corporation, trade name G-3000
Detector: UV detector, detection wavelength 220 nm Eluent: aqueous solution containing sodium sulfate 0.15 mol / L and sodium phosphate 0.05 mol / L Protein denaturation rate (%) = 100 × (A−B) / A
A: Ovalbumin amount immediately after preparation B: Ovalbumin amount after standing for 48 hours

<Cleaning test>
A cleaning performance test was performed using a pseudo-soil plate contaminated with oils.
(1) Preparation of pseudo filth 30 g of beef tallow, 30 g of soybean oil, 0.75 g of monoolein and 0.1 g of oil red were dissolved in 60 mL of chloroform to prepare a pseudo filth bath.
(2) Detergency test 1 g of the above-mentioned pseudo-soil was uniformly applied to a 10 cm × 10 cm glass plate, and then dried in a constant temperature bath at 40 ° C. for 24 hours. Using a portable local cleaning device (YEW300 manufactured by Totoki Co., Ltd.), 100 ml of cleaning liquid was sprayed with standard water discharge, and a pseudo filth plate was placed 10 cm from the spray hole to clean the pseudo filth. The detergency was evaluated by visually observing the degree of removal of the red pseudo-soil, and the detergency was evaluated in the following four stages. The results are shown in Table-1.
[Evaluation criteria]
A: Detergency is very good.
○: Detergency is quite excellent.
Δ: Detergency is slightly superior.
X: Detergency is low.

<Foamability test>
The compositions of Examples 1 to 12 and Comparative Examples 1 to 4 were diluted into 0.1% by weight aqueous solutions, which were used as sample aqueous solutions, and 200 ml of the sample aqueous solution at 25 ° C. in accordance with the Ross Miles method (JIS K3362). After dropping from the height of 900 mm on the liquid surface in 30 seconds, the height of the foam after 3 minutes was measured. The results are shown in the table below.

<Test substance>
In the following display, EO represents —C ₂ H ₄ O—, and PO represents —C ₃ H ₆ O—.
(A component)
A-1 HO (EO) ₁₃₅ (PO) ₅₂ (EO) ₁₃₅ H
A-2 HO (EO) ₁₀₅ (PO) ₄₀ (EO) ₁₀₅ H
A-3 HO (EO) ₇₀ (PO) ₂₀ (EO) ₇₀ H
A-4 HO (PO) ₁₀ (EO) ₁₃₀ (PO) ₁₀ H
A-5 HO (EO) ₄₅ H
A-6 HO (EO) ₅₀ (PO) ₁₀ (EO) ₅₀ H
A-7 HO (PO) ₅ (EO) ₁₀₀ (PO) ₅ H

(B component)
B-1 CH ₃ O (EO) ₄ H
B-2 C ₄ H ₉ O (EO) ₁₀ H
B-3 Ethylene oxide 15 mol adduct of lauryl alcohol B-4 Ethylene oxide 10 mol adduct of 2-ethylhexyl alcohol B-5 Ethylene oxide 25 mol adduct of lauryl alcohol B-6 10 mol of ethylene oxide of lauryl alcohol, propylene
Oxide 3 mol random adduct

(C component)
C-1 Propylene glycol C-2 Glycerin C-3 Polyglycerin (average polymerization degree 6)
C-4 Lauric acid monoester of polyglycerol (average degree of polymerization 6)

(Comparative ingredients)
D-1 Lauryl sulfate sodium salt D-2 Lauryl polyoxyethylene (average polymerization degree 3) sulfate sodium salt D-3 Trimethylmonooleyl ammonium chloride
Examples 1 and 5-15 are reference examples.

  As described above, all of the cleaning liquids containing the surfactant were better than the water alone. However, the comparative example using an anionic surfactant or a cationic surfactant has a large protein denaturation rate, and when used locally, it is expected that irritation increases.

HO (EO) ₄ (PO) ₆₀ (EO) ₄ H (ethylene oxide 9%) and HO (PO) ₄₀ (EO) ₁₀ (PO) ₄₀ H (ethylene oxide 8.6%) were not required for water. Therefore, protein denaturation etc. could not be evaluated.

Claims (4)

As the component (A), the following general formula (1) and / or (2):

(In the formula, p and p ′ each independently represent a number of 5 to 250, q represents a number of 20 to 75, and the total molecular weight of polyethylene oxide in the molecule is 50 to 90 mass of the total molecular weight. %.)

(In the formula, r and r ′ each independently represent a number of 8 to 80, s represents a number of 20 to 400, and the total molecular weight of polyethylene oxide in the molecule is 50 to 90 mass of the total molecular weight. % at a), and (as B) component, the following general formula (3).;

(R is an aliphatic hydrocarbon group having 1 to 30 carbon atoms, A is an alkylene group having 2 to 4 carbon atoms, n represents a number of 1 to 10 when R is 1 to 4 carbon atoms, R represents a number of 8 to 40 when the carbon number is 5 to 30, and (A) component (B) is 0.01 to 10 parts by mass with respect to 1 part by mass of component (A) The cleaning composition for a local cleaning device, wherein the total content of the component (B) and the component (B) is 0.01 to 3% by mass.   As component (C), one or more selected from glycerin, diglycerin, polyglycerin, (di- or poly) glycerin ester, polyalkylene glycol ester, propylene glycol, and dipropylene glycol are contained. The cleaning composition for a local cleaning apparatus according to claim 1.   The local cleaning device according to claim 1, comprising one or more selected from a moisturizer, a chelating agent, an antibacterial agent, a deodorizing agent, a fragrance, a solvent, and a drug. Cleaning composition. The cleaning composition for a local cleaning device according to any one of claims 1 to 3 , wherein the local cleaning device is portable.