JP4602949B2 - Coated particle-containing composition and method for producing the same - Google Patents

Description

  The present invention relates to a method for producing a coated particle-containing composition, a coated particle-containing composition obtained by the production method, and an application of the coated particle-containing composition.

  Prevents granulated particles used as raw materials from deteriorating due to contact with the outside air or moisture, or contact with each other in various fields such as food, feed, pharmaceuticals, quasi drugs, and cosmetics. Therefore, in order to impart fluidity improvement, sustained release property, masking property, elution prevention property, acid resistance, etc., it is widely performed to coat the granulated particles with fats and oils. As a coating method with such fats and oils, a method of coating the granulated particles by spraying liquid fats and oils, or stirring and contacting the core material and the hardened oil powder having a specific melting point or more together at high speed A method of fixing oils and fats to the entire peripheral surface of the core material is known.

For example, in Patent Document 1, even when it has a fine powder of 50 μm or less as a core material, it is possible to easily give coating performance excellent in elution prevention and the like, and coated granular composition excellent in production efficiency A method for producing a product and a composition obtained by the method are described. Patent Document 2 describes a method for producing a double-coated granule having improved in-vivo absorbability of water-soluble vitamins having a particle size of 2 mm or less as a core material and a composition obtained by the method. .
JP-A-11-308985 JP 2004-123636 A

  However, when the water content of the coated granular composition obtained by the method of Patent Document 1 is 20% or more, the present inventor decreases the coating performance of the coated particles, and further when heated by retort sterilization or the like, the coating performance Has been found to decrease further.

As a result of extensive research, the present inventor has found that by using raw egg yolk together, the coating performance of the coated particles in the composition having a high water content is enhanced, and further, it is maintained even under high temperature such as heat treatment. The present invention has been completed.
That is, the present invention
(Step 1) A step of granulating the core material with a substance exhibiting poor water solubility at room temperature,
(Step 2) including a step of coating the particles obtained in Step 1 with oils and fats, and (Step 3) mixing the coated particles obtained in Step 2 above with raw whole eggs or raw egg yolk. A method for producing a coated particle-containing composition characterized in that: (Step 4) the above production method comprising a step of heating the mixture obtained in Step 3; a coated particle-containing composition obtained by these production methods; and this coating The present invention relates to the use of the particle-containing composition.

In the coated particle-containing composition of the present invention, the coated particle coating has good coating performance and imparts excellent sustained release properties, masking properties, and the like to the particles.
In addition, when the functional component contained in the core material has a bitter taste, astringency, or savory taste, the coating performance is reduced in the conventional composition having a high water content, and the functional component is eluted. Therefore, in order to suppress bitterness, astringency, or gummy taste, it was unavoidable to reduce the blending amount, but in the coated particle-containing composition of the present invention, these tastes are masked well, so the functional component The content can be increased, and a useful effect of the functional ingredient can be expected by ingesting a small amount of the composition. The useful effects of the functional component herein include, for example, health promotion effects exhibited by polyphenols such as catechins, that is, carcinogenesis prevention, aging prevention, blood LDL lowering action, blood pressure rise inhibiting, intestinal regulating action , Bactericidal / antibacterial action, deodorizing action, etc.

  In the production method of the present invention, first, the core material is granulated with a substance exhibiting poor water solubility at room temperature (step 1). The core material used in Step 1 is preferably powdery or granular, and the shape thereof may be either spherical or irregular. The particle size (diameter) of the core material is not particularly limited.

  The core material is not particularly limited as long as it is a substance usually used for various foods, feeds, pharmaceuticals, quasi drugs, cosmetics, and the like. Preferably, it is a functional component having a bitter taste, astringency, or savory taste. Specific examples include polyphenols, carotenoids, nucleic acids, heme iron, and inorganic iron. These may be used alone or in combination of two or more. Extracts that are liquid at room temperature can be powdered by freeze drying or spray drying.

  As the polyphenols, any of flavonoids such as flavones, flavonols, flavanones, isoflavones, anthocyanins, flavanols, other non-flavonoids, and derivatives and polymers thereof can be used. Plants containing these compounds, for example, teas such as green tea, oolong tea, black tea, and roasted tea, apple flesh, grape seeds, sunflower seeds, rice bran, and extracts from these plants may be used. Specific examples of the polyphenols include at least one selected from catechin, epicatechin, gallocatechin, catechin gallate, epicatechin gallate, epigallocatechin gallate, and epigallocatechin, and derivatives, polymers, and stereoisomers thereof. The mixture of 2 or more types is mentioned.

Substances that are used to granulate the core material used in the above step 1 and are poorly water soluble at room temperature include fat-soluble substances such as fats and oils; alcohol-soluble proteins such as zein and gluten; pullulan and gelatin Examples thereof include thickening stabilizers that exhibit poor water solubility at high concentrations such as xanthan gum, gum arabic, and sodium caseinate; gelling agents that exhibit poor water solubility at room temperature, such as agar, gellan gum, and carrageenan. Zein is preferred. These substances exhibiting poor water solubility may be used singly or in combination of two or more.
In some cases, the above-mentioned substance exhibiting poor water solubility is dissolved by stirring in a suitable solvent at room temperature or while heating to form a coating liquid, and this coating liquid is used as a core material in Step 1 as a known material such as a nozzle or an atomizer. You may spray and granulate with an atomizer. Examples of the solvent at this time include water, alcohol solutions, and acidic solutions such as acetic acid. The amount used is not particularly limited as long as a substance exhibiting poor water solubility can be dissolved, but usually a coating solution prepared so that the substance exhibiting poor water solubility is 5 to 50% by weight is used.
Moreover, it is desirable to use a plasticizer for improving the film performance. Examples of the plasticizer include medium chain triglyceride, glycerin, free fatty acid, distilled acetic acid monoglyceride and the like. The amount of the plasticizer used is usually 0.1 to 20% by weight, preferably 0.5 to 10% by weight in the coating solution.

To granulate the core material with a substance that is hardly soluble in water at room temperature in Step 1, for example, a fluidized bed granulator or a fluidized bed granulator, which is usually used in the field of pharmaceuticals and foods, is equipped with a stirring blade Stirring fluidized bed granulator, rolling fluidized bed granulator equipped with rolling plates, fluidized bed granulator such as Wurster fluidized bed coating machine, and stirring the powder and adding binder to it. An agitation type granulator that forms granules and an extrusion granulator that extrudes powder at a high pressure together with a binder can be used.
The granulation conditions are not particularly limited. For example, when using a fluid bed granulator, the conditions can be performed under known conditions. Preferably, the condition is such that most of the particles after coating the core material with a substance exhibiting poor water solubility at room temperature exceed 75 μm in diameter (diameter), preferably 75 to 500 μm, particularly preferably 100 to 250 μm. In addition, it is desirable that the blending ratio of the core material and the substance exhibiting poor water solubility at room temperature is appropriately determined so as to be the particle size.
In granulation, a binder can be added as necessary. Examples of the binder include saccharides such as dextrin, lactose, corn starch, and powdered sugar; proteins such as skim milk powder and soy protein; cellulose powder, and the amount used can be appropriately determined based on a known method. For example, it is 5 to 90% by weight. From the viewpoint of moldability, it is preferable to granulate while adding a small amount of water or alcohol to dissolve. Furthermore, as long as the effects of the present invention are not impaired, an antioxidant, a colorant, a fragrance, and the like may be blended as other components.

  Next, the particles obtained in the above step 1 are coated with fats and oils (step 2).

  Examples of fats and oils used in Step 2 include animal fats and oils such as beef tallow, pork tallow and fish oil; vegetable oils and fats such as rapeseed oil, soybean oil, palm oil, palm oil, sesame oil, sesame oil, rice oil and linseed oil Is done. These oils and fats may be refined deodorized oils subjected to oil and fat processing such as curing, fractionation, and transesterification. Moreover, the form of fats and oils can be selected according to the coating method mentioned later, and any of liquid form, semi-solid form, and solid form may be sufficient.

  In step 2, the method of coating the particles obtained in step 1 with oil and fat is not particularly limited, but the particles obtained in step 1 are contacted and collided with a hardened oil powder having a melting point of 40 ° C. or higher. A method of coating the particles by fixing the fats and oils on the peripheral surfaces of the particles, preferably on the entire peripheral surface; and the particles obtained by Step 1 are sprayed with liquid oils in a fluidized bed, and the particles The method B etc. which coat | cover the surrounding surface of this, preferably the whole surrounding surface with the said fats and oils are illustrated. Method A is preferable from the viewpoint of obtaining a uniform coating layer.

As the hardened oil powder having a melting point of 40 ° C. or higher used in the above method A, animal fats such as beef tallow, lard, fish oil; rapeseed oil, soybean oil, palm oil, coconut oil, sesame oil, sesame oil, rice oil, linseed oil, etc. These oils and fats can be used, and those oils and fats that have been subjected to a curing treatment by hydrogenation to have a melting point of 40 ° C. or higher can be used. Further, it may be a refined deodorized oil or the like that has been subjected to oil processing such as fractionation or transesterification, and a melting point of 40 ° C. or higher. In addition, the fats and oils having a melting point of 40 ° C. or higher may be liquid, semi-solid, or solid, and can be appropriately selected depending on the coating method. Rapeseed extremely hardened oil is preferable. The usage form is preferably a powdered solid or liquid form in terms of handleability. These fats and oils may be used alone or in combination of two or more.
The particle diameter (diameter) of these hardened oil powders is preferably about 0.1 to 50 μm, particularly preferably 1 to 10 μm, when the core material having a core material particle size of 50 μm or less is granulated. When granulating a 50-2000 micrometers core material, about 0.01-500 micrometers, especially 0.1-1 micrometer are preferable.

In Method A, the mixing ratio when the hardened oil powder having a melting point of 40 ° C. or higher is brought into contact with and collided with the particles obtained in step 1 is the particle size of the particles and the hardened oil powder. It can be appropriately determined in consideration of the diameter ratio. For example, it is preferable to select particles: hardened oil powder in a weight ratio of 1: 0.01 to 5, particularly 1: 0.05 to 1.
In Method A, the contact / collision between the particles and the hardened oil powder can be performed using, for example, a known powder contacting device such as a high efficiency powder mixing device. The contact / collision condition is such that the surface of the hardened oil powder is melted by contact / collision at a temperature lower than 40 ° C. at which the hardened oil powder having a melting point of 40 ° C. or higher is not melted, and is adhered and fixed to the outer surface of the particle It is not limited.

  Examples of the fats and oils used in Method B include the aforementioned animal fats and oils and vegetable fats and oils. When the fats and oils are semi-solid or solid, they can be used in a liquid state. In Method B, in order to spray the oil and fat in the fluidized bed on the particles obtained in Step 1, for example, the particles are stirred with a stirrer or the like, and the liquid oil or fat is used using a nozzle, an atomizer, or the like. It can carry out by the well-known method etc. which spray. Moreover, although it does not specifically limit about the cooling after granulation, The melted fats and oils should just solidify by cooling, and can cool with cold air etc.

  Next, the coated particles obtained in the step 2 are mixed with the raw whole egg or the raw egg yolk (step 3).

  In Step 3, birds, particularly poultry raw whole eggs or egg yolks can be used, and specifically, whole eggs or egg yolks such as chicken, quail, duck, duck, turkey, pheasant or ostrich can be used. In the present invention, these may be used alone or in combination of two or more. Preferred is a chicken raw whole egg or a raw egg yolk, particularly a raw egg yolk.

In Step 3, the mixing ratio of the coated particles obtained in Step 2 and the raw whole egg or raw egg yolk is not particularly limited, but the coating performance of the coated particles is stable with respect to 100 parts by weight of the raw egg yolk. From the point which shows property, 0.1-30 weight part of coated particles, Preferably it is 1-25 weight part, More preferably, 5-20 weight part can be mixed.
The whole egg may be mixed in such an amount that the amount of egg yolk in the whole egg falls within the range indicated for the above egg yolk.
In Step 3, it is desirable that the coated particles obtained in Step 2 and the raw whole egg or raw yolk are mixed under mild conditions from the viewpoint of maintaining the coating performance of the coated particles. Usually, at normal temperature, the coated particles are slowly added to the raw whole egg or egg yolk, preferably in small portions, and are mixed by stirring or shaking at a low rotational speed.

Next, the mixture of the coated particles obtained in the step 3 and the raw whole egg or the raw egg yolk is heated (step 4).
Conditions for the heating are not particularly limited, and can be appropriately set according to the purpose of heating, for example, cooking, sterilization or sterilization. For example, about 62 to about 65 ° C. and about 30 minutes for low-temperature and long-term sterilization, about 72 to about 75 ° C. and about 15 seconds for high-temperature and short-time sterilization, about 120 to about 140 ° C. and about 0.5 to about For about 4 seconds or about 130 to about 140 ° C., about 0.5 to 4 seconds, retort heat sterilization is about 115 ° C. or more, about 15 minutes or more, about 120 ° C. or more, about 4 minutes or more, respectively.

The present invention also relates to a coated particle-containing composition obtained by the production method. As the coated particle-containing composition of the present invention, (1) a core material obtained by the production method including the above steps 1 to 3, a material layer that covers the surface of the core material and exhibits poor water solubility at room temperature, and this material A coated particle-containing composition comprising coated particles comprising an oily layer covering the outside of the layer, and (2) raw whole egg or raw egg yolk.
Further, as the coated particle-containing composition of the present invention, obtained by the production method including the steps 1 to 4, (1) a core material, and a substance layer exhibiting poor water solubility at room temperature covering the surface of the core material; A coated particle-containing composition comprising a coated particle having an oil and fat layer covering the outside of the substance layer, and (2) whole egg or egg yolk is also included.
The particle size of the coated particles is not particularly limited, but is preferably 75 to 500 μm in order to have excellent coating performance.

  The coated particle-containing composition of the present invention has additives, such as fats and oils, particularly polyunsaturated fatty acids, sugars, starches, dextrins, seasonings, sweeteners, pH adjusters, as long as the effects of the present invention are not impaired. An agent, a thickener, a fragrance, a pigment, or an emulsifier may be contained.

The coated particle-containing composition of the present invention can contain a polyunsaturated fatty acid. This coated particle-containing composition can be prepared according to the aforementioned method using raw whole egg or raw egg yolk added with a polyunsaturated fatty acid in advance. At this time, it is not necessary to go through a special emulsification step that has been conventionally performed.
Examples of the polyunsaturated fatty acid include docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), eicosapentaenoic acid (EPA), arachidonic acid, linoleic acid, α-linolenic acid, and γ-linolenic acid. . In the present invention, fish oil, preferably refined fish oil, can be used as fats and oils rich in polyunsaturated fatty acids.
Here, when polyphenols such as catechin are used as the core material, the polyunsaturated fatty acid is prevented from being oxidized over time, and it is a composition having a high content of both, and can be stored for a long time with less unpleasant taste and unpleasant odor. A possible coated particle-containing composition is obtained.

The coated particle-containing composition of the present invention can be used as food, medicine, cosmetics and the like. In particular, it can be used as a cooked food packaged food such as a heated food, especially a retort food or a dessert in a cup container.
In the coated particle-containing composition of the present invention, the coating performance of the coated particles is stable even when containing a large amount of moisture.
The amount of water in the coated particle-containing composition is not particularly limited, but is preferably 20 to 100% by weight, more preferably 50 to 95% by weight, and particularly preferably 70 to 90% by weight.
Examples of the composition having a large amount of water include foods and pharmaceuticals that are liquid, gel, sol, and mixtures thereof, and may contain solids. Examples include, but are not limited to, milk shakes, pudding, tea fumigation, and jelly.
In the present invention, food includes animal feed, health food, functional food, and the like, and pharmaceutical includes quasi-drug and the like.

  Since the coated particle-containing composition of the present invention is a gel-like or sol-like composition having a high water content and can contain a large amount of functional components, it can be used for food for the elderly and / or those with difficulty in swallowing. It can be suitably used as a medicine.

  Hereinafter, the present invention will be described in more detail by way of examples. The present invention is not limited by the examples. In addition, unless otherwise indicated,% shows weight%.

Production Example 1 Production of coated particles Catechin powder (trade name “Polyphenon 70A”, manufactured by Mitsui Norin Co., Ltd.) 500 g together with 100 g of crystalline cellulose and 50 g of dextrin, fluidized bed granulator (trade name “Flow Coater Mini”, Freund Industries ( Co., Ltd.), coating solution 255g [Zein (trade name "Showa Zein DP" Showa Sangyo Co., Ltd.) 30.0g, lecithin 25.0g, medium chain fatty acid (MCT oil) 9.5g 70% alcohol It was prepared by dissolving in 190.5 g of an aqueous solution] and granulated. As the granulation conditions, the air supply amount and the liquid supply amount were adjusted so that the air supply temperature was 70 ° C and the product temperature was 35 ° C. Subsequently, 319.5 g of the obtained granulated product was used, 180 g of rapeseed extremely hardened oil fine powder having an average particle size of 3 × 10 ⁻³ mm was added, and a stirring granulator (trade name “OMD-3 type” Nara) was added. Coated particles were obtained by stirring for 20 minutes under the conditions of an in-machine temperature of 25 ° C., nitrogen gas filling, and a main shaft rotation speed of 1,000 rpm and a sub shaft rotation speed of 2,000 rpm. The obtained particles had a particle size of 1.1 mm and a yield of 92%.

Example 1
Raw egg yolk and milk are added to water and mixed so that the final blending concentration in the retort pudding shown in Table 1 is mixed, and then black tea extract, starch, gelling agent (trade name “Takaragen ALX-B3” (stock) ) Manufactured by Takaragen), and a part of upper white sugar is added and mixed. Further, the remaining amount of the coated catechin particles and upper white sugar obtained in Production Example 1 are added and mixed, heated to 80 ° C. and dispersed. A purine solution was prepared. The purine liquid was filled in a container and sterilized at 121 ° C. for 20 minutes, and then cooled to produce a retort pudding.

Example 2
Retort pudding was produced in the same manner as in Example 1 except that raw whole egg was used instead of raw egg yolk.

Example 3
A retort pudding was produced in the same manner as in Example 1 except that fish oil (trade name “High Power 27DHA Oil” manufactured by Bell Rich) was mixed with raw egg yolk in advance.

Comparative Example 1
Retort pudding was produced in the same manner as in Example 1 except that uncoated catechin powder (trade name “Polyphenone 70A” manufactured by Mitsui Norin Co., Ltd.) was used instead of the coated particles obtained in Production Example 1 above. .

Comparative Examples 2 and 3
Retort in the same manner as in Example 1 except that dried egg yolk ("Dried Egg Yolk D-1" manufactured by Kewpie Co., Ltd.) or egg yolk oil ("York Oil HF" manufactured by Kewpie K.K.) was used instead of egg yolk. Made pudding.

Comparative Example 4
Retort pudding was produced in the same manner as in Example 1 except that raw egg yolk was not used.

Comparative Example 5
The mixture of the coated particles obtained in Production Example 1 above, sucrose, and starch, and the mixture of raw egg yolk, milk, and black tea extract were retort sterilized at 121 ° C. for 20 minutes, respectively. Subsequently, both were mixed, a gelling agent (trade name “Takaragen ALX”, manufactured by Takaragen Co., Ltd.) was added and mixed, and the mixture was heated to 80 ° C. and dispersed to obtain a pudding solution. The purine liquid was filled in a container and cooled. Each of the above raw materials was used so as to have a final blending concentration in the retort pudding shown in Table 1.

Sensory test About the retort pudding manufactured above, the sensory evaluation of the flavor was performed. The sensory evaluation was performed by having 10 panelists (5 men and 5 women) eat each retort pudding. The bitterness was scored according to the following evaluation criteria, and the average score was shown.
Evaluation criteria 4 points: No bitterness 3 points: Somewhat bitter taste 2 points: Bitter taste 1 point: Very strong bitterness In addition, the panelists gargle before eating retort pudding.
The results are shown in Table 1.

  From the above results, it is recognized that the bitter taste of catechin can be suppressed by using raw whole eggs or raw egg yolks. In particular, when Example 1 and Comparative Example 1 were compared, the bitter taste was not suppressed by raw egg yolk in Comparative Example 1 even though the amount of catechin was small. It can be seen that this is because the raw egg yolk increased the stability of the coated particles against retort heating.

Claims (11)

(Step 1) A step of granulating the core material with a substance exhibiting poor water solubility at room temperature,
(Step 2) including the step of coating the particles obtained in Step 1 with oil and fat, and (Step 3) the step of mixing the coated particles obtained in Step 2 with raw whole egg or raw egg yolk. A method for producing a coated particle-containing composition.   The manufacturing method of Claim 1 in which a core material contains the functional component which has a bitter taste, astringency, or a savory taste.   The production method according to claim 2, wherein the functional component having a bitter taste, astringency, or savory taste is a polyphenol, a carotenoid, a nucleic acid, heme iron, or inorganic iron.   The production method according to claim 3, wherein the polyphenol is catechin. (Step 4) The method according to any one of claims 1 to 4, further comprising a step of heating the mixture obtained in Step 3.   The manufacturing method of Claim 5 whose heating of the process 4 is retort sterilization. A coated particle-containing composition obtained by the production method according to any one of claims 1 to 4,
(1) coated particles comprising a core material, a material layer that is sparingly soluble in water at room temperature that covers the surface of the core material, and an oil and fat layer that covers the outside of the material layer; and (2) raw whole eggs Or the composition containing raw egg yolk. A coated particle-containing composition obtained by the production method according to claim 5 or 6,
(1) coated particles comprising a core material, a material layer that is sparingly soluble in water at room temperature that coats the surface of the core material, and an oil and fat layer that coats the outside of the material layer; and (2) whole eggs or A composition comprising egg yolk.   The coated particle-containing composition according to claim 8, which is a heated food.   The coated particle-containing composition according to claim 9, which is a cooked container packaged food.   The coated particle-containing composition according to any one of claims 7 to 10, which is a food for elderly people and / or those who have difficulty chewing swallowing.