JP4587683B2 - Dosing device - Google Patents

Description

  The present invention relates to a dosing device used for administering powdery medicinal powder to mucous membranes such as lungs by inhaling a patient's breath.

  Various kinds of this kind of dispenser have been proposed. Patent document 1 discloses the medication device as the example.

  As shown in FIG. 3, the prescription device 100 of the above document is composed of a prescription device main body 101 and a housing 102 that is slidable and rotatable on the outer periphery of the prescription device main body 101. A powder storage chamber 104 is formed in the prescription device main body 101. The powder storage chamber 104 is partitioned into a front chamber 104a and a rear chamber 104b by being partitioned by a partition wall 103 having a large number of small holes 103a. ing.

  A suction port 105 is formed on the front end side of the prescription device main body 101 so as to open the front chamber 104a of the powder storage chamber 104. The entire rear chamber 104b of the powder storage chamber 104 is formed on the rear end side of the prescription device main body 101. An opening 106 that opens is formed. A rib 107 projects from the rear chamber 104 b so as to face the opening 106. The housing 102 covers the opening 106 of the prescription device main body 101, and a capsule insertion port 108 is formed at a position covering the opening 106.

In the above configuration, a capsule 110 containing a medicinal powder (not shown) is inserted from the capsule inlet 108. When the capsule 110 is inserted, the front cap 110 a of the capsule 110 is held in a state of protruding into the drug powder storage chamber 104. Next, the housing 102 is rotated with respect to the prescription device main body 101. Then, the rib 107 collides with the front cap 110a of the capsule 110, the front cap 110a is detached from the rear cap 110b, and the powder (not shown) in the capsule 110 is opened to the powder storage chamber 104. Next, the patient holds the front end side of the prescription device body 101 in the mouth and sucks it. Then, the inside of the powder storage chamber 104 is depressurized, and by this depressurization, the powder is sucked from the patient's mouth, and the sucked powder is adhered to the lung mucous membrane, for example. Further, when sucking from the nose, the front end side of the prescription device body 101 is pushed into the nose and sucked, and the sucked drug powder adheres to the mucous membrane of the nose, for example. Since the front cap 110a of the capsule 110 that has fallen into the powder storage chamber 104 is prevented from moving to the front chamber 104a by the partition wall 103, the patient does not suck the front cap 110a.
JP-A-1-27750

  By the way, since the powdery medicinal powder has a property of easily condensing, there is a high possibility that it exists as a condensed lump. And in the said prior art example, the powder which exists as a condensed lump is attracted | sucked from a patient's mouth by the pressure reduction of the powder storage chamber 104. FIG. Therefore, since it is not sucked in a sufficiently miniaturized state, there is a high possibility that the medicinal powder does not reach the deepest part such as the lung.

  This invention is made | formed in view of the situation mentioned above, and the objective of this invention is providing the suction | inhalation medication device which can make a powder reach | attain to the deepest part, such as a lung.

In order to achieve the above object, the invention described in claim 1 includes a housing having a main body sliding hole opened at one end, a storage position accommodated in the main body sliding hole of the housing, and the main body sliding. A dosing device body slidably provided between a moving position and a disengagement position separated from the moving hole, and in the dosing device body, a powder storing chamber for storing the powder, and the powder storing chamber The vent is disposed at a position where the housing is closed by the housing at the storage position and is opened to the atmosphere at the release position, and the drug powder storage chamber is communicated with the outside. An inhalation port disposed at a position closed by the housing is provided at the storage position, and a seal member is provided between the inner peripheral surface of the main body sliding hole of the housing and the outer peripheral surface of the prescription device main body. Install and pull out from the position of this seal member And purpose in that a said vent hole toward the rear position.

According to a second aspect of the present invention, there is provided a housing having a main body sliding hole opened at one end side, a storage position accommodated in the main body sliding hole of the housing, and a detachment separated from the main body sliding hole. A prescription device body slidably provided between the position and the drug substance storage chamber for storing the drug powder in the prescription device body, and the outside provided in the drug powder storage chamber. In addition, the vent is opened to the atmosphere while being disposed at the position closed by the housing at the storage position, and communicates with the powder powder storage chamber and the outside at the separation position, and the housing at the storage position. An inhalation port disposed at a position that is opened without being blocked by a sealing member, and a seal member is provided between the inner peripheral surface of the main body sliding hole of the housing and the outer peripheral surface of the prescription device main body. The rear direction of the pull-out direction from the position of the seal member Wherein the purpose in that a vent to.

According to the first aspect of the present invention, when the prescription device body located at the storage position with respect to the housing is moved in the pulling direction, the inside of the powder storage chamber of the prescription device body is gradually depressurized, and the vent hole of the prescription device body is brought into the atmosphere. When it is pulled out to the open position, the air suddenly flows into the powder powder storage chamber from the vent hole, and the powder condensate mass is crushed and decomposed into fine particles by the inflow air pressure. Then, when the patient sucks the suction port of the prescription device main body from the mouth or nose, the finely divided drug powder is sucked from the patient's mouth. Accordingly, the medicinal powder can reach the deepest part such as the lung. In addition, the pressure inside the powder storage chamber is reduced, and the condensate of powder powder is crushed and broken down into fine particles by the inflow air pressure that flows rapidly, so that the powder in the powder storage chamber is not scattered outside. Can be crushed. Further, since the suction port of the prescription device main body is closed by the housing at the housing position, it is not necessary to perform a process or work for closing the suction port when the prescription device main body is pulled out from the housing.
In addition, since the sealing member can reliably prevent air from entering through the gap between the housing and the prescription device body in the process of pulling out the prescription device body, the inside of the powder storage chamber of the prescription device body is sufficiently depressurized, and the ventilation holes When the air is released to the atmosphere, a very intense inflow air pressure can be generated. Therefore, the condensed lump of the drug powder can be reliably pulverized to form fine particles.

According to the second aspect of the present invention, when the inhaler is closed and the main body of the prescription device located in the storage position with respect to the housing is moved in the pulling direction, the inside of the powder storage chamber of the main body of the prescription device is gradually depressurized. When the air vent of the container body is pulled out to the position where it is open to the atmosphere, the air suddenly flows into the powder storage chamber from the air vent, and the condensate of the powder is crushed by the inflow air pressure that suddenly flows into the powder. Breaks down into granules. Then, when the patient sucks the suction port of the prescription device main body from the mouth or nose, the finely divided drug powder is sucked from the patient's mouth. Accordingly, the medicinal powder can reach the deepest part such as the lung. In addition, the pressure inside the powder storage chamber is reduced, and the condensate of powder powder is crushed and broken down into fine particles by the inflow air pressure that flows rapidly, so that the powder in the powder storage chamber is not scattered outside. Can be crushed.
In addition, since the sealing member can reliably prevent air from entering through the gap between the housing and the prescription device body in the process of pulling out the prescription device body, the inside of the powder storage chamber of the prescription device body is sufficiently depressurized, and the ventilation holes When the air is released to the atmosphere, a very intense inflow air pressure can be generated. Therefore, the condensed lump of the drug powder can be reliably pulverized to form fine particles.

(First embodiment)
Hereinafter, a first embodiment embodying the present invention will be described with reference to the drawings.

  FIG. 1 is a cross-sectional view of a dosing device 1 for administering powder from the patient's mouth. In FIG. 1, a prescription device 1 includes a cylindrical housing 2 having a main body sliding hole 2a opened at one end side, and a storage position (position in FIG. 1) accommodated in the main body sliding hole 2a of the housing 2. The prescription device main body 3 is slidably provided between the main body sliding hole 2a and the separation position.

  The housing 2 is formed of, for example, a synthetic resin material and has a cylindrical shape. The prescription device main body 3 is formed in a cylindrical shape by combining, for example, two members of a synthetic resin material, and a drug powder storage chamber 4 is formed therein. The medicinal powder storage chamber 4 has an elongated cylindrical shape along the axial direction and accommodates medicinal powder powder (not shown). A circumferential groove (not shown) is formed on the outer peripheral surface of the prescription device main body 3, and the seal member 5 is fixed so as to be partially inserted into the circumferential groove. The seal member 5 seals the inner surface of the main body sliding hole 2 a of the housing 2 and the outer peripheral surface of the prescription device main body 3.

  In addition, the prescription device main body 3 is provided with a vent hole 6 and a suction port 7 for communicating the powder storage chamber 4 with the outside. The vent hole 6 is disposed at a position where it is closed by the housing 2 in the storage position of the prescription device main body 3, more specifically, at a rear position in the extraction direction A with respect to the position of the seal member 5. The inhalation port 7 is disposed on the rear end surface portion 3 a of the prescription device main body 3 in the drawing direction A. The rear end side of the prescription device body 3 in which the inhalation port 7 is formed is set to a desired size that is easy for the patient to hold in the mouth.

  A method of using the above-mentioned prescription device 1 will be described. It is assumed that a predetermined powder is stored in the powder storage chamber 4 of the prescription device main body 3 for a patient who receives medication. As shown in FIG. 1, the prescription device main body 3 located at the storage position is moved in the pulling-out direction A. Then, the inside of the powder storage chamber 4 of the prescription device main body 3 is gradually depressurized, and when the vent hole 6 of the prescription device main body 3 is pulled out to a position where it is opened to the atmosphere, the atmosphere is discharged from the vent hole 6 into the powder storage chamber 4. The condensate of powder is crushed and broken down into fine particles by the inflow air pressure. Then, the patient sucks the suction port 7 while holding the rear end side of the prescription device body 3 in the mouth. Then, external air flows into the medicinal powder storage chamber 4 from the vent hole 6, and the medicinal powder that has been atomized on the inflowed air is sucked into the patient's mouth from the inhalation port 7. Since the finely divided drug powder is sucked from the patient's mouth, the drug powder can reach the deepest part such as the lung.

  Further, the inside of the powder storage chamber 4 is depressurized, and the condensed powder lump is pulverized and decomposed into fine particles by the inflow air pressure that flows rapidly. It can be crushed without being scattered.

  Furthermore, since the inhalation port 7 of the prescription device body 3 is closed by the housing 2 in the storage position, it is necessary to perform processing and work for closing the inhalation port 7 when the prescription device body 3 is pulled out from the housing 2. Absent.

  In the first embodiment, the seal member 5 is provided between the inner peripheral surface of the main body sliding hole 2 a of the housing 2 and the outer peripheral surface of the prescription device main body 3, and the pulling direction A is more than the position of the seal member 5. Since the vent hole 6 is disposed at the rear position, the sealing member 5 can reliably prevent the atmosphere from entering through the gap between the housing 2 and the prescription device body 3 in the process of pulling out the prescription device body 3. When the inside of the powder storage chamber 4 is sufficiently depressurized and the vent hole 6 is opened to the atmosphere, a very intense inflow air pressure can be generated. Therefore, the condensed lump of the drug powder can be reliably pulverized to form fine particles.

(Second Embodiment)
Hereinafter, a second embodiment of the present invention will be described with reference to the drawings.

  FIG. 2 is a cross-sectional view of the dosing device 11 for administering the powder from the patient's mouth. In FIG. 2, the prescription device 11 includes a cylindrical housing 12 having a main body sliding hole 12a opened at one end side, and a storage position (position in FIG. 1) accommodated in the main body sliding hole 12a of the housing 12. It is comprised from the prescription device main body 13 provided slidably between the detachment | leave positions removed from the main body sliding hole 12a.

  The housing 2 is formed of, for example, a synthetic resin material and has a cylindrical shape. The prescription device main body 13 is formed in a cylindrical shape by combining two members of, for example, flexible synthetic resin material, and a drug powder storage chamber 14 is formed therein. The medicinal powder storage chamber 14 is an elongated space along the axial direction, in which medicinal powder powder (not shown) is accommodated. A circumferential groove (not shown) is formed on the outer peripheral surface of the prescription device main body 14, and the seal member 15 is fixed so as to be partially embedded in the circumferential groove. The seal member 15 seals between the inner surface of the main body sliding hole 12 a of the housing 12 and the outer peripheral surface of the prescription device main body 13. Further, the seal member 15 is provided on the rear end side as much as possible with respect to the drawing direction A of the prescription device main body 13. Thereby, the substantial withdrawal stroke S of the prescription device main body 13 (the distance that the seal member 15 of the prescription device main body 13 slides on the inner surface of the main body sliding hole 12a of the housing 12 when sliding from the storage position to the disengagement position). It is set to be as long as possible.

  In addition, the prescription device main body 13 is provided with a vent 16 and an inhalation port 17 for communicating the powder storage chamber 14 with the outside. The vent hole 16 is disposed at a position where it is closed by the housing 12 in the storage position of the prescription device main body 13, more specifically, at a rear position in the extraction direction A with respect to the position of the seal member 15. The suction port 17 is disposed on the distal end surface portion 13b in the pulling direction A of the prescription device body 13, and the powder storage chamber 14 is opened to the atmosphere by the suction port 17 even at the housing position of the housing 12. The distal end side of the prescription device main body 13 in which the inhalation port 17 is formed is set to a desired dimension that is easy for the patient to hold in the mouth.

  The usage method of the above-mentioned prescription device 11 will be described. It is assumed that a predetermined powder is stored in the powder storage chamber 14 of the prescription device main body 13 for a patient who receives medication. As shown in FIG. 2, the inhalation port 17 is closed by compressing and deforming the distal end side of the prescription device main body 13 or by plugging an obturator (not shown). The prescription device body 13 to be moved is moved in the pulling direction A. Then, the inside of the powder storage chamber 14 of the prescription device main body 13 is gradually depressurized, and when the vent hole 16 of the prescription device main body 13 is pulled out to a position where it is opened to the atmosphere, the atmosphere is passed through the vent hole 16 into the powder storage chamber 14. The condensate of powder is crushed and broken down into fine particles by the inflow air pressure. Then, after opening the state where the suction port 17 is closed, the patient sucks the suction port 17 while holding the distal end side of the prescription device body 13 in the mouth. Then, external air flows into the powder storage chamber 14 from the vent hole 16, and the powdered powder on the air that has flowed in is sucked into the patient's mouth from the suction port 17. Since the finely divided drug powder is sucked from the patient's mouth, the drug powder can reach the deepest part such as the lung.

  Further, the inside of the powder storage chamber 14 is depressurized, and the condensed powder lump is pulverized and decomposed into fine particles by the inflow air pressure that flows rapidly. It can be crushed without being scattered.

  In the second embodiment, the seal member 15 is provided between the inner peripheral surface of the main body sliding hole 12 a of the housing 12 and the outer peripheral surface of the prescription device main body 13, and the pulling direction A is more than the position of the seal member 15. Since the vent hole 16 is disposed at the rear position, the sealing member 15 can reliably prevent the atmosphere from entering through the gap between the housing 12 and the prescription device body 13 in the process of pulling out the prescription device body 13. When the inside of the 13 powder storage chambers 14 is sufficiently depressurized and opened to the atmosphere in the vent hole 16, a very intense inflow air pressure can be generated. Therefore, the condensed lump of the drug powder can be reliably pulverized to form fine particles.

  In the second embodiment, the seal member 15 is provided on the rear end side as much as possible with respect to the withdrawal direction A of the prescription device body 3, and is set so that the substantial withdrawal stroke S of the prescription device body 13 is as long as possible. Yes. Therefore, when the inside of the powder storage chamber 14 of the prescription device main body 13 is sufficiently depressurized and opened to the atmosphere in the vent hole 16, a very intense inflow air pressure can be generated. Therefore, the condensed lump of the drug powder can be reliably pulverized to form fine particles. In addition to the structure of the seal member 15, the suction port 17 is disposed on the distal end side in the pulling direction A of the prescription device main body 13, so that the arrangement position of the vent hole 16 and the suction port 17 is the drug powder storage chamber. 14 separate positions. Therefore, when the patient is aspirated, the air sucked from the vent hole 16 is discharged from the suction port 17 while passing through the whole area of the medicinal powder storage chamber 14. Is sucked from the suction port 17 smoothly on the suction flow.

  In the first and second embodiments, the prescription devices 1 and 11 that the patient or the like sucks from the mouth have been described, but the present invention can be similarly applied to a prescription device that the patient or the like sucks from the nose. In the case of a prescription device for inhalation from the nose, the rear end side or the front end side of the prescription device main bodies 3 and 13 in which the suction ports 7 and 17 are formed are dimensioned so as to be in close contact with the nose or put into the nose. Is set.

  The present invention can be embodied in another embodiment as follows. In the following other embodiments, the same operations and effects as those of the above embodiment can be obtained.

  (1) In the said 1st and 2nd embodiment, it was set as the structure which forms only one ventilation hole 6 and 16 in the prescription device main bodies 3 and 13. FIG. On the other hand, you may make it the structure which forms a some ventilation hole. By setting it as such a structure, the effect that the airflow which flows in in the powder storage chambers 4 and 14 can be adjusted to a suitable direction and pressure at the time of grind | pulverizing the condensed lump of powder is acquired.

1 shows a first embodiment of the present invention and is a cross-sectional view of a dispensing device. FIG. FIG. 6 is a cross-sectional view of a dispensing device, showing a second embodiment of the present invention. It is sectional drawing of the conventional medication device.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1,11 Dosage device 2,12 Housing 2a, 12a Main body sliding hole 3,13 Dosage device main body 4,14 Drug powder storage chamber 5,15 Seal member 6,16 Vent hole 7,17 Inhalation port

Claims (2)

Provided slidably between a housing having a main body sliding hole opened on one end side, and a housing position accommodated in the main body sliding hole of the housing and a disengagement position separated from the main body sliding hole. And a medicine powder storage chamber for storing the powder powder, and the outside provided in the powder powder storage chamber communicates with the outside, and is closed by the housing at the storage position. In addition, the air vent arranged at a position opened to the atmosphere at the disengagement position communicates with the powder powder storage chamber and the outside, and the suction port arranged at a position closed by the housing at the accommodation position the door is provided,
A seal member is provided between the inner peripheral surface of the main body sliding hole of the housing and the outer peripheral surface of the prescription device main body, and the vent hole is disposed at a rear position in the pulling direction from the position of the seal member. A dispenser characterized by. Provided slidably between a housing having a main body sliding hole opened on one end side, and a housing position accommodated in the main body sliding hole of the housing and a disengagement position separated from the main body sliding hole. And a medicine powder storage chamber for storing the powder powder, and the outside provided in the powder powder storage chamber communicates with the outside, and is closed by the housing at the storage position. The vent hole opened to the atmosphere at the disengagement position and the powder powder storage chamber communicate with the outside at the disengagement position, and disposed at a position where the housing position is opened without being blocked by the housing. Provided with a suction port ,
A seal member is provided between the inner peripheral surface of the main body sliding hole of the housing and the outer peripheral surface of the prescription device main body, and the vent hole is disposed at a rear position in the pulling direction from the position of the seal member. A dispenser characterized by.

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