JP4570290B2 - Biosensor cartridge and biosensor dispensing device - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention provides a biosensor cartridge containing a plurality of biosensors capable of quickly and easily quantifying specific components in various biological samples, and a plurality of measurements can be performed by loading the biosensor cartridge. It relates to a possible biosensor dispensing device.
[0002]
[Prior art]
In recent years, various biosensors (sensors) using a specific catalytic action of an enzyme have been developed, and biosensors capable of measuring rapidly and accurately have been put into practical use while being applied to clinical fields.
[0003]
Taking glucose sensors as an example, today's increase in the number of diabetic patients is remarkable, and in order to measure and manage blood glucose levels, it is very complicated to centrifuge blood and measure plasma as in the past. Therefore, a sensor capable of measuring whole blood is required, and the present applicant has already proposed a biosensor capable of satisfying this demand in Japanese Patent Application Laid-Open No. 61-294351. In these measurements, a dedicated voltage is supplied to the sensor electrode system from a dedicated measuring instrument, the current value flowing between the electrodes is measured, and the substrate concentration in the sample solution is calculated based on this signal. Is shown on the display unit of the measuring instrument.
[0004]
FIG. 15 is an exploded perspective view of a general conventional biosensor currently used.
In the figure, a counter electrode 53 and a measurement electrode 54, leads 51 and 52 connected to them, and an insulating layer 55 are provided on a substrate 50. A reaction layer (not shown) containing an enzyme and a mediator (electron acceptor) is formed so as to cover the counter electrode 53 and the measurement electrode 54. A cover 58 is fixed on the substrate 50 via a spacer (insulating layer) 55. Reference numeral 57 denotes a sample supply hole, from which a test liquid (sample) is introduced onto the counter electrode 53 and the measurement electrode 54 by capillary action. With the introduction of the test solution, the internal air is discharged from the air hole 59. Reference numeral 56 denotes a reverse insertion prevention protrusion, which can prevent reverse insertion of the sensor 62 into the biosensor measuring device main body.
[0005]
FIG. 16 is a schematic external view of a conventional packaging bag, and is a form of a biosensor that is currently most frequently used.
In the figure, the packaging bag 61 comprises an upper packaging bag 63 and a lower packaging bag 64. The packaging bag 61 packages the sensor 62. Reference numeral 70 denotes a desiccant.
[0006]
As for biosensors and measuring instruments, sensor packs in which a plurality of biosensors are set as described in JP-A-8-262026 have already been commercialized.
In addition, a biosensor dispensing device has been developed that can perform multiple measurements by loading the sensor pack into a measuring instrument and operating a knob. In such a biosensor dispensing device, for a user such as a diabetic patient with many elderly people, when attaching the sensor to the attachment port of the measuring instrument main body, the sensor may be accidentally dropped, or the sensor may be reversed. Complicated aspects such as the case where measurement is performed while being inserted or further inserted in the opposite direction have been improved.
[0007]
FIG. 17 is a schematic diagram of a conventional biosensor dispensing device.
In the figure, a plurality of sensors 69 are accommodated radially in a circular sensor pack 67 with reference to the center of the circle. For the measurement, the sensor pack 67 is loaded into the biosensor dispensing device 68, and the slide button attached to the upper part of the biosensor dispensing device 68 is automatically moved from the sensor pack 67 to the sensor 69 by the L-shaped two-action slide operation. And is set at the measurement position of the biosensor dispensing device 68. The set sensor 69 is electrically connected to the biosensor dispensing device 68 through the electrode of the biosensor.
[0008]
The subject attaches a very small amount of blood, which is a sample sample, to the sample supply hole at the tip of the sensor 69, whereby the electric circuit is automatically turned on and a predetermined voltage is supplied to the sensor electrode. The electric circuit of the biosensor dispensing device 68 measures the value of the current flowing between the sensor electrodes, calculates the substrate concentration in the sample solution based on this signal, and measures the value of the biosensor dispensing device 68. Shown on the value indicator.
[0009]
The conventional biosensor dispensing device is configured as described above, and multiple measurements can be performed by simply setting the sensor at the measurement position by simply operating the slide button. For a user such as a patient, it is possible to prevent a handling error such as reverse insertion of the sensor in measurement use.
[0010]
[Problems to be solved by the invention]
Since there are many elderly people and a large proportion of people with physical disabilities, users of biological information measuring devices using such biosensors are easy to handle at the time of measurement using the measuring device and can be operated with weak force. There is a need for further improvements in ease of measurement, such as being possible and easily recognizing measurement results.
[0011]
However, in the conventional biosensor dispensing device, for example, in the operation method of the biosensor dispensing device disclosed in Japanese Patent Application Laid-Open No. 8-262026, the slide button (slide latch) is sent out by a two-action slide operation with the thumb. When the sensor is set at the measurement position and separated after the measurement is finished, there is a problem that a complicated measurement operation of sliding the slide button in the reverse direction at the time of sending the sensor is required.
[0012]
In addition, it is required to make the measuring device more convenient for biosensors that are currently popular. In other words, it is desired that a biosensor single-spec product that is widely used at present can be measured by attaching the biosensor to a dispensing device manually and manually. Further, from the viewpoint of hygiene such as infection prevention, it is desired from the measurer side that the measurement can be performed in a non-contact manner as much as possible with respect to the biological sample of the subject.
[0013]
In order to solve the conventional problems as described above, the present invention is a biosensor cartridge containing a simple biosensor for measuring a specific component in a biological sample such as blood easily, quickly, and with high accuracy, Another object of the present invention is to provide a biosensor dispensing device that is easy to handle.
[0014]
[Means for Solving the Problems]
The present invention uses a biosensor cartridge in which a plurality of biosensors are stacked in a cascade and housed in a housing when performing a target biometric measurement, and the biosensor dispensing device is loaded with the sensor cartridge, By simply turning on and off the lever of the dispensing device, the biosensor in the biosensor cartridge can be sent out and set at the measurement position, and the sensor can be separated at the end of the measurement.
[0015]
In addition, by providing a storage box so that the separated and separated sensors can be temporarily secured in the measuring device, it becomes possible to discard a plurality of accumulated sensors at once and improve the complexity after measurement. It is a thing.
Furthermore, the biosensor mounting part at the time of measurement is configured so that measurement can be performed by adopting a structure capable of manually mounting a current popular type biosensor single-spec product.
[0016]
As described above, the present invention is intended to provide a biosensor cartridge and a biosensor dispensing device that house a biosensor that can easily and easily perform biometric measurement.
[0017]
That is, this departure Tomorrow A biosensor cartridge capable of storing a plurality of biosensors for detecting a specific component in a sample, wherein the biosensors are stacked and stored in a casing, and the casing is a biosensor as a measuring instrument. Each of the biosensors can be measured by operating the biosensor dispensing device when the sample is loaded in the dispensing device and the target sample is measured.
[0018]
In addition, this departure Tomorrow , Said In the biosensor cartridge, the biosensor is positioned at a normal delivery position by pressing in the stacking direction with an elastic material, and is sequentially sent out by pressing the biosensor in a direction perpendicular to the stacking direction. It is characterized by this.
[0019]
In addition, this departure Tomorrow , Said In the biosensor cartridge, the outer shape is an asymmetric three-dimensional shape.
[0020]
In addition, this departure Tomorrow , Said The biosensor cartridge includes a sensor delivery port and a sensor delivery knob insertion port, and the sensor delivery port and the sensor delivery knob insertion port are in a sealed state after a sensor detachment operation by the biosensor dispensing device. It is characterized by.
[0021]
In addition, this departure Tomorrow , Said In the biosensor cartridge, a desiccant is incorporated.
[0022]
In addition, this departure Tomorrow A biosensor dispensing device for setting a biosensor at a measurement position and performing a target sample measurement, wherein the biosensor cartridge is loaded, and a biosensor cartridge case is obtained by reciprocating a knob by lever operation. The biosensor is sent out and taken out to the measurement position, and the biosensor electrode and the sensor electrode connection contact on the biosensor dispensing device side are connected to obtain electrical data from the biosensor. It is what.
[0023]
In addition, this departure Tomorrow , Said In the biosensor dispensing device, the used biosensor can be detached by operating the lever after the measurement is completed.
[0024]
In addition, this departure Tomorrow , Said The biosensor dispensing apparatus includes a slide rail base, and the slide rail base sets the biosensor at a measurement position by two lever operations for one biomeasurement, and removes the sensor after the measurement. This is characterized in that a series of operations can be performed at the end of measurement.
[0025]
In addition, this departure Tomorrow , Said In the biosensor dispensing apparatus, the slide rail base is provided with a reverse movement prevention hook that prevents the lever from moving in the reverse direction when the lever is operated.
[0026]
In addition, this departure Tomorrow , Said In the biosensor dispensing device, the measurement set position of the biosensor is provided on one side opposite to the side where the lever is disposed, and the loading port of the biosensor cartridge is also located on one side opposite to the side It is provided.
[0027]
In addition, this departure Tomorrow , Said The biosensor dispensing apparatus is characterized in that a measurement value display for displaying a measurement value measured by the biosensor is provided on one side surface that does not hinder lever operation.
[0028]
In addition, this departure Tomorrow , Said In the biosensor dispensing apparatus, the biosensor packaged in the biosensor packaging bag for each sensor is manually inserted into the biosensor dispensing apparatus.
[0029]
In addition, this departure Tomorrow , Said In the biosensor dispensing device, the biosensor packaged in the biosensor packaging bag has a sensor electrode connection point that is electrically connected to the sensor electrode connection contact block by the reverse insertion prevention protrusion of the sensor. It is characterized in that it is measured when it is manually inserted into the biosensor dispensing device.
[0030]
In addition, this departure Tomorrow , Said The biosensor dispensing apparatus includes a sensor disposal case, and the sensor disposal case is configured to temporarily store a plurality of used biosensors.
[0031]
In addition, this departure Tomorrow , Said In the biosensor dispensing apparatus, the sensor disposal case is transparent or translucent.
[0032]
DETAILED DESCRIPTION OF THE INVENTION
Embodiments of the present invention will be described below.
Embodiment 1 FIG.
Embodiment 1 of the present invention will be described by taking as an example a blood glucose level measuring apparatus that is currently most widely used.
FIG. 1 is a schematic diagram of a biosensor cartridge 1 containing a sensor 62 that is an example of Embodiment 1 of the present invention.
The biosensor cartridge 1 includes an inner case 3 and an outer case 2.
[0033]
FIG. 2 is a schematic view of a biosensor cartridge / inner case which is an example of the first embodiment of the present invention, and FIG. 3 is a schematic diagram of the biosensor cartridge / one case of the first embodiment of the present invention. The structure perspective view of an inner case is shown.
In the figure, the biosensor cartridge / inner case stacks and houses a plurality of sensors 62.
[0034]
A sensor delivery port 8 and a sensor delivery knob insertion port 9 for delivering the stacked sensors 62 to the outside are provided on the left and right sides of the bottom surface of the inner case 3. A sealed door 6 is attached to the sensor delivery port 8 so that the sensor delivery port 8 is sealed except when the sensor 62 is delivered.
[0035]
A rod spring 7 is attached to the sealing door 6, and the sealing door 6 is normally closed by the rod spring 7. An elastic rubber material 13 such as silicon rubber is attached to the opening / closing part, and the sensor outlet 8 is sealed.
[0036]
When the lowest sensor of the sensor 62 stacked and accommodated in the inner case 3 is sent out from the sensor delivery port 8, it is attached to the sensor presser spring (elastic material) 4 in order to correctly guide the next sensor to the delivery position. The top surface of the uppermost sensor 62 stacked and stored is pressed by the sensor presser plate 5. As a result, all the sensors housed in the stack are correctly set at the delivery position.
[0037]
FIG. 4 is an assembly structure diagram of a biosensor cartridge, which is an example of Embodiment 1 of the present invention.
In the figure, similarly to the inner case 3, the outer case 2 is also provided with a sensor outlet 11 and a sensor delivery knob insertion port 12 for sending the stacked sensors 62 to the outside on the left and right sides of the bottom surface. . A sealed door 10 is attached to the sensor delivery knob insertion port 12, and the sensor delivery knob insertion port 12 is sealed similarly to the sealed door 6 of the inner case 3 except when the sensor 62 is delivered.
[0038]
The dimensional relationship between the ridge lines AA ′ and BB ′ of the outer case 2 is AA ′> BB ′, and the sensor cartridge 1 is restricted in the direction of the position. The inner case 3 is accommodated in the outer case 2, and in FIG. 4, the surface where the ridgelines C, D, E, and F of the inner case 3 overlap with the outer case 2 is in close contact welding. Therefore, the biosensor housed in a stacked manner has a sealed structure that is shut off from the outside air by the sealed door 6 and the sealed door 10 provided in the inner case 3 and the outer case 2, respectively.
[0039]
Further, a desiccant 60 is attached on the sensor press plate of the inner case 3 to prevent the influence of humidity and to guarantee the sensor performance.
[0040]
FIG. 5 is a side view of biosensor dispensing apparatus 14 which is an example of Embodiment 1 of the present invention, and FIG. 6 is a biosensor which is an example of Embodiment 1 of the present invention. It is a front view of the dispensing apparatus.
[0041]
In order to easily handle the biosensor dispensing device 14 with either the left or right hand, the measurement value display 32 is provided on one side that does not interfere with the operation of the lever 44, that is, on the back side of the biosensor dispensing device 14. Yes. Further, the cartridge loading lid 18, the biosensor measurement position, and the lever 44 are also attached to the side surface of the biosensor dispensing device 14.
[0042]
Hereinafter, the operation of the biosensor dispensing apparatus 14 which is an example of the first embodiment of the present invention will be described.
The biosensor cartridge 1 opens the cartridge loading lid 18 disposed on one side opposite to the side on which the lever 44 is disposed, and loads the biosensor cartridge 1 into the biosensor dispensing device 14. By reciprocating the lever 44 by gripping the lever 44 with a finger, the sensor delivery knob 15 is slid and the sensor on the bottom surface of the sensor cartridge 1 is delivered. The sensor 62 is slid to the sensor electrode connection contact base 20 which is the measurement position, and the sensor 62 is set.
[0043]
The measurement is completed by operating the lever 44 twice for one measurement of the biological value. The sensor 62 is set at the measurement position by the first operation of the lever 44, and after the sample sample is spotted, the sensor is detached by the second operation of the lever 44 and the measurement is completed. This operation is realized by a slide block (slide rail base) 26.
[0044]
Next, the operation of the slide block 26 will be described.
FIG. 7 is a schematic diagram of a slide block of the biosensor dispensing apparatus which is an example of Embodiment 1 of the present invention, and FIG. 8 is a front view and a side view of the slide block.
[0045]
In the figure, an introduction groove 35 is provided in the slide block 26. The introduction groove 35 is formed on a circumference around the lever shaft 23.
In FIG. 8, the gray portion of the introduction groove 35 has a shallow groove depth, and the white portion has a deep depth. The introduction groove 35 is connected as shown in the figure and is endless.
[0046]
The slide block 26 is supported by slide rails 27, 28, and 29 fixed to the outer case 19 of the biosensor dispensing device 14, and slides in the left-right direction. Further, a lever introduction protrusion 34 fixed to and attached to the lever 44 is slidably engaged and meshed with the introduction groove 35 provided in the slide block 26.
[0047]
The lever 44 is supported by a lever shaft 23 fixedly supported by the outer case 19. In FIG. 5, the shape of the support portion of the lever shaft 23 of the lever 44 is not circular but is a rectangular shape extending in the direction of the slide block 26, and the elastic force of the lever shaft support spring 24 supported by the lever 44. Is supported.
[0048]
The lever 44 is constantly applied with a force of pushing back in the forward direction by the lever driving spring 25. When the measurement is completed, the lever 44 is always at the position of the lever 44 and the lever introduction protrusion 34 shown in FIGS. 5 and 6.
[0049]
In the first lever operation, the lever introduction protrusion 34 of the lever 44 slides to the upper end of the rightmost groove of the slide block 26. At this time, as shown in FIG. 8, the gray portion of the introduction groove 35 in the slide block has a shallow groove depth, so that the lever 44 is lifted in the direction of the lever shaft 23. Accordingly, the saw teeth 36 and 37 provided on the lever 44 and the sensor delivery knob 15 are engaged with each other, and the sensor delivery knob 15 is slid in the direction in which the sensor 62 is pushed out only for the length of the shallow portion of the groove of the slide block 26. The pushing stroke is designed to be a distance to the measurement position of the sensor 62, and the sensor 62 is set at the measurement position. The lever 44 moves to the upper end of the rightmost groove of the slide block 26, and no further lever operation is possible.
[0050]
Next, when the lever 44 is released, the second introduction groove slides from the right side of the slide block 26 and stops moving to the second lowest end thereof. Since the second introduction groove 35 is deep, the lever 44 is pushed down by the elastic force of the lever shaft support spring 24. Accordingly, the saw teeth 36 and 37 provided on the lever 44 and the sensor delivery knob 15 are disengaged from each other, and the sensor delivery knob 15 remains stationary. At this point, the specimen sample is spotted on the set sensor 62 and measurement is performed.
[0051]
The second lever operation is performed to release the sensor after measurement.
The position of the lever 44 after the measurement is at the second lowest end from the right side of the slide block 26. When the lever 44 is operated, the lever introduction projection 34 slides to the third groove upper end from the right of the slide block 26. At this time, as shown in FIG. 8, the third gray portion from the right of the introduction groove 35 in the slide block has a shallow groove depth, so that the lever 44 is the same as the first lever operation. It is lifted in the direction of the shaft 23. Accordingly, the saw teeth 36 and 37 provided on the lever 44 and the sensor delivery knob 15 are engaged with each other, and the sensor delivery knob 15 is slid in the direction in which the sensor 62 is pushed out only for the length of the shallow portion of the groove of the slide block 26. The pushing stroke is designed to be a distance from the measurement position of the sensor 62 until the sensor is detached, and the sensor is detached from the biosensor dispensing device 14.
[0052]
Next, the lever 44 moves from the right side of the slide block 26 to the upper end of the third groove. When the lever 44 is released, the leftmost introduction groove of the slide block 26 is slid to the lowermost end, and is moved to the initial position of the slide block 26 and stopped. At this time, since the introduction groove 35 of the slide block 26 is also designed to be shallow, the sensor delivery knob 15 is engaged with the lever 44 and the saw teeth 36 and 37 provided on the sensor delivery knob 15, and returns to the initial position and stops. As shown in FIG. 8, reverse movement prevention claws 46, 47, 48, and 49 are provided at the upper end and the lower end of the introduction groove 35 of the slide block 26 so that the sliding portion of the lever introduction protrusion 34 does not reversely move. I have to.
[0053]
With the above operation, one measurement operation is completed.
FIG. 9 is a schematic view of a sensor electrode connection contact block of a biosensor dispensing apparatus according to an embodiment of the present invention, and FIG. 10 is a sensor of a biosensor dispensing apparatus according to an embodiment of the present invention. It is a schematic diagram at the time of operation | movement of an electrode connection contact stand.
[0054]
In FIG. 9, sensor electrode connection contacts 21 and 22 are provided on the sensor electrode connection contact base 20 in order to connect the sensor 62 and the electric circuit of the biosensor dispensing device 14.
[0055]
Next, the operation of the sensor electrode connection contact base 20 will be described.
In FIG. 10, when the sensor 62 is transported to a normal position on the sensor electrode connection contact base 20, the sensor electrode connection contacts 21 and 22 and the electrodes 65 and 66 of the sensor 62 are electrically connected. The electric circuit formed by the sensor electrode connection contacts 21 and 22 and the sensor 62 is connected by a flexible substrate 39.
[0056]
When a very small amount of blood, which is a specimen sample of the subject, is attached to the sample supply hole 57 at the tip of the sensor 62, a minute current is detected by the voltage applied to the sensor electrodes 65 and 66 from the electric circuit, The electric circuit turns on automatically. The electric circuit of the biosensor dispensing device 14 measures the value of the current flowing between the sensor electrodes 65 and 66, and based on this signal, calculates the substrate concentration in the sample solution by a microcomputer (not shown). It is displayed on the measurement value display 32 of the biosensor dispensing device 14.
[0057]
As shown in FIG. 10, in the state where the sensor 62 is connected, the top surfaces of the sensor 62 and the sensor electrode connection contact base 20 are pressed by the reverse insertion preventing protrusion 56 of the sensor 62 and become parallel. The sensor electrode connection contacts 21 and 22 are pressed against the sensor electrodes 65 and 66 to be electrically connected.
[0058]
FIG. 11 is a sensor mounting operation diagram of the biosensor dispensing apparatus according to the embodiment of the present invention using a sensor cartridge. As shown in FIG. 11, when the sensor 62 is not in the measurement position, the electrode connection contact block 20 is supported by the contact block moving spring 40 at an angle of about 30 degrees.
[0059]
In this way, by connecting the sensor electrode connection contacts 21 and 22 to the sensor electrodes 65 and 66 only at the regular measurement position of the sensor 62, wear during the sliding of the sensor can be eliminated and reliability can be ensured. .
[0060]
As described above, the biosensor cartridge of the first embodiment can accommodate a plurality of sensors in a column and can be measured by the biosensor dispensing apparatus of the first embodiment.
[0061]
In addition, the biosensor dispensing apparatus according to the first embodiment enables manual attachment measurement of the sensor 62 even for the general-purpose sensor 62 packaged (packed) in the conventional biosensor packaging bag shown in FIG. To do.
[0062]
FIG. 12 is a manual sensor mounting operation diagram of the biosensor dispensing apparatus that is an example of the first embodiment of the present invention using a single sensor.
In the figure, a sensor guide spring 38 is provided on the electrode connection contact base 20 in order to guide a manual insertion sensor at a normal position. As shown in FIG. 11, the sensor guide spring 38 is pressed down against the bottom surface of the sensor delivery knob 15 during automatic loading measurement using the sensor cartridge 1 and does not hinder sensor conveyance.
[0063]
Further, when the sensor 62 is manually inserted, the electrode connection contact base 20 is provided with a reverse insertion preventing hook 30 for preventing reverse insertion of the sensor 62. By preventing reverse insertion of the sensor 62, the sensor electrodes 65 and 66 are not connected to the sensor electrode connection contacts 21 and 22.
[0064]
FIG. 13 is a front view and a side view of a sensor disposal case mounting specification product of the biosensor dispensing apparatus which is an example of the first embodiment of the present invention, and FIG. 14 is a diagram of the embodiment of the present invention. It is a side view at the time of the discard operation | movement of the case attachment specification goods for sensor disposal of the biosensor dispensing apparatus which is one Example.
[0065]
In the figure, a sensor disposal case 31 is attached to the biosensor dispensing device 14 so that used sensors can be temporarily stored and discarded together. The sensor disposal case 31 is slid along the stationary rib 43 by the fixing rib 43 provided on the biosensor dispensing device 14 side and the slit 45 provided in the sensor disposal case 31.
[0066]
When the sensor 62 is detached from the biosensor dispensing device 14, the sensor disposal case 31 is slid, and a plurality of detached sensors are temporarily stored so that they can be discarded at a later time, thereby improving measurement complexity. can do.
[0067]
The sensor disposal case 31 is transparent or translucent. As a result, the quantity of the used sensors 62 can be easily understood, and it is easy to replenish the sensors.
[0068]
As described above, in the first embodiment, the sensor cartridge 1 containing a plurality of biosensors 62 is loaded into the biosensor dispensing device 14 and the simple lever 44 is operated, so that the sensor 62 is reliably placed at the measurement position. Can be loaded. Further, the single sensor 62 packaged in the conventional packaging bag 61 can also be measured by manual insertion as in the past. Furthermore, since the used sensors after the measurement are temporarily stored and can be collectively discarded, it is possible to reduce troublesomeness and labor at the time of measurement.
[0069]
As described above, the present invention No ba The Io sensor cartridge is a biosensor cartridge that can store a plurality of biosensors for detecting a specific component in a sample, and the biosensors are stacked and stored in a casing, and the casing is a measuring instrument. The biosensor dispenser is loaded and the measurement of each sample is possible by operating the biosensor dispenser when measuring the target sample. There is an effect that it can be easily performed.
[0070]
Main departure Tomorrow , Said In the biosensor cartridge, the biosensor is positioned at a normal delivery position by pressing in the laminating direction with an elastic material, and is sequentially delivered by pressing the biosensor in a direction perpendicular to the laminating direction. Therefore, there is an effect that the biosensor can be arranged by being pressed against the cartridge delivery position and can be easily delivered sequentially.
[0071]
Main departure Tomorrow , Said Since the outer shape of the biosensor cartridge is an asymmetrical three-dimensional shape, it has an insertion direction restriction when the biosensor cartridge is loaded into the measuring instrument, and can prevent the cartridge from being loaded in the reverse direction. There is an effect.
[0072]
Main departure Tomorrow , Said The biosensor cartridge includes a sensor delivery port and a sensor delivery knob insertion port, and the sensor delivery port and the sensor delivery knob insertion port are in a sealed state after a sensor detachment operation by the biosensor dispensing device. There is an effect that circulation of outside air can be prevented.
[0073]
Main departure Tomorrow , Said In the biosensor cartridge, since the desiccant is built in, there is an effect that the characteristic deterioration of the reagent substance used in the biosensor can be prevented and the maintenance of the sensor performance can be guaranteed.
[0074]
Main departure Tomorrow A biosensor dispensing device for setting a biosensor at a measurement position and performing a target sample measurement, wherein the biosensor cartridge is loaded, and a biosensor cartridge case is obtained by reciprocating a knob by lever operation. Since the biosensor was sent out and carried out to the measurement position, the biosensor electrode and the sensor electrode connection contact on the biosensor dispensing device side were connected to obtain electrical data from the biosensor. The measurement value is obtained by the processing, and the measurement value can be displayed on the display provided in the dispensing device.
[0075]
Main departure Tomorrow , Said Since the biosensor dispensing apparatus is configured to allow the used biosensor to be detached by the lever operation after the measurement is completed, there is an effect that the used biosensor can be easily discarded.
[0076]
Main departure Tomorrow , Said The biosensor dispensing apparatus includes a slide rail base, and the slide rail base sets the biosensor at a measurement position by operating the lever twice for one biomeasurement, and removes the biosensor after the measurement. Since a series of operations is possible to end the measurement, in the biosensor dispensing device, the biosensor is set to the measurement position by the reciprocating movement of the lever, and the used biosensor is detached at the end of the measurement. Sometimes, a series of operations can be easily performed.
[0077]
Main departure Tomorrow , Said In the biosensor dispensing device, the slide rail base is provided with a reverse movement preventing hook that prevents the lever from moving in the reverse direction when the lever is operated, and therefore, there is an effect that the lever can be operated reliably.
[0078]
Main departure Tomorrow , Said In the biosensor dispensing device, the measurement set position of the biosensor is provided on one side opposite to the side where the lever is disposed, and the loading port of the biosensor cartridge is also located on one side opposite to the side Because it is provided, each component of the biosensor dispensing device is arranged so that the operation during measurement can be easily performed, and the effect that measurement can be easily performed with either the left or right hand There is.
[0079]
Main departure Tomorrow , Said In the biosensor dispensing device, the measurement value display that displays the measurement value measured by the biosensor is provided on one side that does not interfere with the lever operation, so it can be easily operated with either the left or right hand. There is an effect that the measured value can be read.
[0080]
Main departure Tomorrow , Said In the biosensor dispensing device, the biosensor packaged in the biosensor packaging bag for each sensor is manually inserted into the biosensor dispensing device, so the current popular biosensor can be used. There is an effect that the convenience of the measuring device can be increased.
[0081]
Main departure Tomorrow , Said In the biosensor dispensing device, the biosensor packaged in the biosensor packaging bag has a sensor electrode connection point electrically connected to the sensor electrode connection contact block and the sensor in parallel by the reverse insertion prevention protrusion of the sensor. Since it was made to measure when it was manually inserted into the biosensor dispensing device, the current popular type biosensor can be used, and the convenience of the measuring device can be increased. There is.
[0082]
Main departure Tomorrow , Said The biosensor dispensing device includes a sensor disposal case, and the sensor disposal case is configured to temporarily store a plurality of used biosensors. There is an effect that the measurement can be efficiently performed on the biological sample of the subject person with minimal contact.
[0083]
Main departure Tomorrow , Said In the biosensor dispensing device, the sensor disposal case has a transparent or translucent color, so that the amount of used biosensor can be easily grasped, and the timing of disposal can be clearly identified. There is an effect.
[Brief description of the drawings]
FIG. 1 is a schematic diagram of a biosensor cartridge, which is an example of Embodiment 1 of the present invention.
FIG. 2 is a schematic diagram of a biosensor cartridge / inner case which is an example of the first embodiment of the present invention.
FIG. 3 is a structural perspective view of a biosensor cartridge / inner case which is an example of the first embodiment of the present invention.
FIG. 4 is an assembly structure diagram of a biosensor cartridge, which is an example of Embodiment 1 of the present invention.
FIG. 5 is a side view of a biosensor dispensing apparatus that is an example of the first embodiment of the present invention.
FIG. 6 is a front view of a biosensor dispensing apparatus that is an example of the first embodiment of the present invention.
FIG. 7 is a schematic diagram of a slide block of the biosensor dispensing apparatus that is one example of the first embodiment of the present invention.
FIG. 8 is a front view (a) and a side view (b) of a slide block of a biosensor dispensing apparatus that is an example of Embodiment 1 of the present invention.
FIG. 9 is a schematic diagram of a sensor electrode connection contact block of the biosensor dispensing apparatus that is one example of the first embodiment of the present invention.
FIG. 10 is a schematic diagram during operation of the sensor electrode connection contact block of the biosensor dispensing apparatus that is one example of the first embodiment of the present invention.
FIG. 11 is a sensor mounting operation diagram of the biosensor dispensing apparatus according to the first embodiment of the present invention using a biosensor cartridge.
FIG. 12 is a manual sensor mounting operation diagram of the biosensor dispensing apparatus according to the first embodiment of the present invention when a conventional single sensor is used.
FIGS. 13A and 13B are a side view and a front view of a sensor disposal case mounting specification product of the biosensor dispensing apparatus according to the first embodiment of the present invention. FIGS.
FIG. 14 is a side view of the biosensor dispensing apparatus according to the first embodiment of the present invention during a disposal operation of a product with a sensor disposal case attached specification.
FIG. 15 is an exploded perspective view of a conventional biosensor.
FIG. 16 is a schematic external view of a conventional biosensor packaging bag.
FIG. 17 is a schematic diagram of a conventional biosensor dispensing apparatus.
[Explanation of symbols]
1 Biosensor cartridge
2 Outer case
3 Inner case
4 Sensor presser spring
5 Sensor presser plate
6,10 Sealed door
7,7 'bar spring
8,11 Sensor outlet
9,12 Sensor feed knob insertion slot
13, 13 'elastic rubber material
14,68 Biosensor dispensing device
15 Sensor sending knob
16, 17 knob rail
18 Cartridge loading lid
19 Exterior case
20 Sensor electrode connection contact block
21, 22 Sensor electrode connection contact
23 Lever shaft
24 Lever shaft support spring
25 Lever drive spring
26 Slide block
27, 28, 29 Slide rail
30 Reverse insertion prevention
31 Sensor disposal case
32 Measured value display
33 Circuit board
34 Lever introduction protrusion
35 Introduction groove
36, 37 sawtooth
38 Sensor guide spring
39 Flexible substrate
40 Spring for moving the contact block
41 Contact stand support shaft
42 exterior ribs
43 Fixing rib
44 lever
45 slits
46, 47, 48, 49 Reverse movement prevention
50 substrates
51,52 lead
53 Counter electrode
54 Measuring pole
55 Spacer
56 Reverse insertion prevention protrusion
57 Sample supply hole
58 Cover
59 Air hole
60,70 Desiccant
61 Biosensor cartridge
62,69 sensors
63 Upper packaging material
64 Lower packaging material
65,66 Sensor electrode
67 Sensor pack

Claims (4)

A biosensor cartridge capable of storing a plurality of biosensors for detecting a specific component in a sample,
Provided with a housing consisting of an inner case and an outer case,
The biosensors are stacked and stored in the inner case of the casing,
The case is loaded into a biosensor dispensing device as a measuring instrument,
When performing the sample measuring object, by the operation of the biosensor dispensing device, Ri Do allow measurement of each biosensor,
The inner case of the housing, and the bottom left and right sides of the outer case are provided with a sensor sending outlet and a sensor sending knob insertion opening,
The sensor delivery port and the sensor delivery knob insertion port are in a sealed state after the sensor detachment operation by the biosensor dispensing device.
A biosensor cartridge characterized by the above. The biosensor cartridge according to claim 1, wherein
The biosensor is positioned at a normal delivery position by pressing in the laminating direction with an elastic material, and is sequentially delivered by pressing the biosensor in a direction perpendicular to the laminating direction.
A biosensor cartridge characterized by the above. The biosensor cartridge according to claim 1, wherein
The bottom surface of the outer case of the housing has a trapezoid in which the ridge line of the outer case on the side provided with the sensor delivery port on the left and right sides of the outer case is longer than the ridge line of the outer case on the side provided with the sensor sending knob insertion port. Has become,
A biosensor cartridge characterized by the above. The biosensor cartridge according to claim 1 , wherein
Contains desiccant,
A biosensor cartridge characterized by the above.

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