JP4533626B2 - アレルギー性好酸球性疾患を治療するための抗原アレイ - Google Patents

アレルギー性好酸球性疾患を治療するための抗原アレイ Download PDF

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JP4533626B2
JP4533626B2 JP2003542209A JP2003542209A JP4533626B2 JP 4533626 B2 JP4533626 B2 JP 4533626B2 JP 2003542209 A JP2003542209 A JP 2003542209A JP 2003542209 A JP2003542209 A JP 2003542209A JP 4533626 B2 JP4533626 B2 JP 4533626B2
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protein
antigen
virus
amino acid
eotaxin
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JP2005514347A (ja
JP2005514347A5 (enExample
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バッハマン，マルチン
ゲーリー ジェニングス，
イーフォ ゾンデレッガー，
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サイトス バイオテクノロジー アーゲー
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Priority claimed from PCT/EP2002/012455 external-priority patent/WO2003040164A2/en
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0007—Nervous system antigens; Prions
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
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    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/5437—IL-13
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    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6075—Viral proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • A—HUMAN NECESSITIES
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    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
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  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2003542209A 2001-11-07 2002-11-07 アレルギー性好酸球性疾患を治療するための抗原アレイ Expired - Fee Related JP4533626B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US33104501P 2001-11-07 2001-11-07
US60/331,045 2001-11-07
US10/050,902 2002-01-18
US10/050,902 US7264810B2 (en) 2001-01-19 2002-01-18 Molecular antigen array
US39663602P 2002-07-19 2002-07-19
US60/396,636 2002-07-19
PCT/EP2002/012455 WO2003040164A2 (en) 2001-11-07 2002-11-07 Antigen arrays presenting il-5, il-3 or eotaxin for treatment of allergic eosinophilic diseases

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JP2005514347A JP2005514347A (ja) 2005-05-19
JP2005514347A5 JP2005514347A5 (enExample) 2009-03-26
JP4533626B2 true JP4533626B2 (ja) 2010-09-01

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JP (1) JP4533626B2 (enExample)
IL (1) IL161147A (enExample)
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RU (1) RU2319503C2 (enExample)

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KR20080047564A (ko) * 2005-09-28 2008-05-29 사이토스 바이오테크놀로지 아게 인터루킨-1 컨쥬게이트 및 그의 용도
BR122020027042B1 (pt) * 2008-08-05 2022-11-08 Toray Industries, Inc Uso de um agente indutor de imunidade, uso de um polipeptídeo e uso de um vetor recombinante
HK1201857A1 (en) * 2011-10-31 2015-09-11 F. Hoffmann-La Roche Ag Antibody formulations
AU2013312971B2 (en) * 2012-09-05 2019-04-18 Medicago Inc. Picornavirus-like particle production in plants
RU2622004C2 (ru) * 2012-10-05 2017-06-08 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Способы получения молекулярных конструкций, содержащих антигенные эпитопы актуальных аллергенов и сигнальные пептиды, обладающие иммунорегуляторными свойствами
JP6086378B2 (ja) * 2012-11-30 2017-03-01 国立大学法人お茶の水女子大学 組み換えヒト膵臓リパーゼの調製方法
MA40824A (fr) 2014-10-22 2017-08-29 Saiba Gmbh Particules de cmv de type virus modifié

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JPH05506145A (ja) * 1990-04-06 1993-09-16 コモンウエルス・サイエンティフィック・アンド・インダストリアル・リサーチ・オーガニゼイション 修飾ポチウイルス外被タンパク質に基づく自己ポリマー化発現系
AU770802B2 (en) * 1998-10-21 2004-03-04 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Virus-like particles for the induction of autoantibodies
WO2000065058A1 (en) * 1999-04-23 2000-11-02 Pharmexa A/S Method for down-regulating il5 activity

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IL161147A (en) 2010-05-31
MXPA04003901A (es) 2004-07-08
JP2005514347A (ja) 2005-05-19
RU2004117072A (ru) 2005-10-27
RU2319503C2 (ru) 2008-03-20

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