JP4446887B2 - オオアワガエリ花粉アレルゲンＰｈｌＰ７に基づく低アレルゲン性アレルギーワクチン - Google Patents
オオアワガエリ花粉アレルゲンＰｈｌＰ７に基づく低アレルゲン性アレルギーワクチン Download PDFInfo
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- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
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- 108020004707 nucleic acids Proteins 0.000 description 1
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- 150000007523 nucleic acids Chemical class 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- YPZRWBKMTBYPTK-UHFFFAOYSA-N oxidized gamma-L-glutamyl-L-cysteinylglycine Natural products OC(=O)C(N)CCC(=O)NC(C(=O)NCC(O)=O)CSSCC(C(=O)NCC(O)=O)NC(=O)CCC(N)C(O)=O YPZRWBKMTBYPTK-UHFFFAOYSA-N 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 150000008300 phosphoramidites Chemical class 0.000 description 1
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- 238000001556 precipitation Methods 0.000 description 1
- 238000002953 preparative HPLC Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
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- 230000008569 process Effects 0.000 description 1
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- 125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 description 1
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- 238000003127 radioimmunoassay Methods 0.000 description 1
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- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical class CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 description 1
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- ZGYICYBLPGRURT-UHFFFAOYSA-N tri(propan-2-yl)silicon Chemical compound CC(C)[Si](C(C)C)C(C)C ZGYICYBLPGRURT-UHFFFAOYSA-N 0.000 description 1
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Botany (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Lock And Its Accessories (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02021837A EP1403280B1 (en) | 2002-09-27 | 2002-09-27 | Hypoallergenic allergy vaccines based on the timothy grass pollen allergen Phl p 7 |
| PCT/EP2003/010701 WO2004029083A1 (en) | 2002-09-27 | 2003-09-25 | Hypoallergenic allergy vaccines based on the timothy grass pollen allergen phl p 7 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006515984A JP2006515984A (ja) | 2006-06-15 |
| JP2006515984A5 JP2006515984A5 (enExample) | 2006-11-02 |
| JP4446887B2 true JP4446887B2 (ja) | 2010-04-07 |
Family
ID=31970337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004539028A Expired - Fee Related JP4446887B2 (ja) | 2002-09-27 | 2003-09-25 | オオアワガエリ花粉アレルゲンＰｈｌＰ７に基づく低アレルゲン性アレルギーワクチン |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7425333B2 (enExample) |
| EP (1) | EP1403280B1 (enExample) |
| JP (1) | JP4446887B2 (enExample) |
| AT (1) | ATE303402T1 (enExample) |
| AU (1) | AU2003277906B2 (enExample) |
| CA (1) | CA2500234A1 (enExample) |
| DE (1) | DE60205907T2 (enExample) |
| DK (1) | DK1403280T3 (enExample) |
| ES (1) | ES2244708T3 (enExample) |
| PT (1) | PT1403280E (enExample) |
| WO (1) | WO2004029083A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT501101B1 (de) * | 2004-12-02 | 2008-01-15 | Biomay Ag | Protein-allergen-derivat |
| EP2000531A1 (en) * | 2007-06-06 | 2008-12-10 | Biomay AG | Antigen presenting cells |
| FI20085601A0 (fi) * | 2008-06-18 | 2008-06-18 | Valtion Teknillinen | Menetelmä uusien hypoallergeenien valmistamiseksi immuuniterapiaa varten |
| GB201002559D0 (en) | 2010-02-15 | 2010-03-31 | Circassia Ltd | Birch peptides for vaccine |
| WO2015077442A2 (en) * | 2013-11-20 | 2015-05-28 | La Jolla Institute For Allergy And Immunology | Grass pollen immunogens and methods and uses for immune response modulation |
| CA2931112A1 (en) * | 2013-11-20 | 2015-05-28 | La Jolla Institute For Allergy And Immunology | Pan pollen immunogens and methods and uses for immune response modulation |
| WO2015131053A1 (en) * | 2014-02-28 | 2015-09-03 | Alk-Abelló A/S | Polypeptides derived from phl p and methods and uses thereof for immune response modulation |
| AU2018286932A1 (en) | 2017-06-23 | 2020-01-16 | Mabylon Ag | Anti-allergen antibodies |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2317724A1 (en) * | 1998-01-09 | 1999-07-15 | Circassia Limited | Methods and compositions for desensitisation |
| JP2002501748A (ja) * | 1998-01-31 | 2002-01-22 | ユニバーシティ オブ アーカンソー | アレルギー反応を減少させるための方法および試薬 |
-
2002
- 2002-09-27 PT PT02021837T patent/PT1403280E/pt unknown
- 2002-09-27 ES ES02021837T patent/ES2244708T3/es not_active Expired - Lifetime
- 2002-09-27 EP EP02021837A patent/EP1403280B1/en not_active Expired - Lifetime
- 2002-09-27 DE DE60205907T patent/DE60205907T2/de not_active Expired - Lifetime
- 2002-09-27 DK DK02021837T patent/DK1403280T3/da active
- 2002-09-27 AT AT02021837T patent/ATE303402T1/de not_active IP Right Cessation
-
2003
- 2003-09-25 US US10/529,441 patent/US7425333B2/en not_active Expired - Fee Related
- 2003-09-25 AU AU2003277906A patent/AU2003277906B2/en not_active Ceased
- 2003-09-25 WO PCT/EP2003/010701 patent/WO2004029083A1/en not_active Ceased
- 2003-09-25 CA CA002500234A patent/CA2500234A1/en not_active Abandoned
- 2003-09-25 JP JP2004539028A patent/JP4446887B2/ja not_active Expired - Fee Related
-
2008
- 2008-08-11 US US12/189,703 patent/US20090074801A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20060216314A1 (en) | 2006-09-28 |
| DE60205907D1 (de) | 2005-10-06 |
| US7425333B2 (en) | 2008-09-16 |
| ES2244708T3 (es) | 2005-12-16 |
| EP1403280A1 (en) | 2004-03-31 |
| EP1403280B1 (en) | 2005-08-31 |
| AU2003277906A1 (en) | 2004-04-19 |
| JP2006515984A (ja) | 2006-06-15 |
| CA2500234A1 (en) | 2004-04-08 |
| AU2003277906B2 (en) | 2008-04-03 |
| US20090074801A1 (en) | 2009-03-19 |
| DE60205907T2 (de) | 2006-02-16 |
| DK1403280T3 (da) | 2005-11-07 |
| PT1403280E (pt) | 2005-11-30 |
| ATE303402T1 (de) | 2005-09-15 |
| WO2004029083A1 (en) | 2004-04-08 |
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