JP4392473B2 - ホスホリパーゼｄの活性の調節 - Google Patents
ホスホリパーゼｄの活性の調節 Download PDFInfo
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- JP4392473B2 JP4392473B2 JP2000604837A JP2000604837A JP4392473B2 JP 4392473 B2 JP4392473 B2 JP 4392473B2 JP 2000604837 A JP2000604837 A JP 2000604837A JP 2000604837 A JP2000604837 A JP 2000604837A JP 4392473 B2 JP4392473 B2 JP 4392473B2
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
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- A61K31/02—Halogenated hydrocarbons
- A61K31/035—Halogenated hydrocarbons having aliphatic unsaturation
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- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
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- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US12519499P | 1999-03-18 | 1999-03-18 | |
| US60/125,194 | 1999-03-18 | ||
| PCT/US2000/006669 WO2000054761A2 (en) | 1999-03-18 | 2000-03-14 | Regulation of phospholipase d activity |
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| Publication Number | Publication Date |
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| JP2002539156A JP2002539156A (ja) | 2002-11-19 |
| JP2002539156A5 JP2002539156A5 (enExample) | 2005-05-19 |
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| ES (1) | ES2344138T3 (enExample) |
| HK (1) | HK1043306B (enExample) |
| WO (1) | WO2000054761A2 (enExample) |
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| US5650435A (en) * | 1991-04-01 | 1997-07-22 | Madara; James L. | Modulation of inflammation related to columnar epithelia |
| WO2000048092A2 (en) * | 1999-02-12 | 2000-08-17 | Mount Sinai Hospital | System for electronically managing, finding, and/or displaying biomolecular interactions |
| US6745204B1 (en) * | 1999-02-12 | 2004-06-01 | Mount Sinai Hospital | System for electronically managing, finding, and/or displaying biomolecular interactions |
| CA2615917C (en) * | 1999-03-18 | 2011-10-04 | Brigham And Women's Hospital | Use of lipoxin compounds for inhibiting of tnf-(alpha)initiated neutrophil response |
| WO2000054761A2 (en) * | 1999-03-18 | 2000-09-21 | Brigham And Women's Hospital | Regulation of phospholipase d activity |
| HK1043357B (en) | 1999-03-18 | 2005-12-09 | The Brigham And Women's Hospital, Inc. | LIPOXIN compound and its use |
| EP1586550A1 (en) * | 1999-03-18 | 2005-10-19 | The Brigham And Women's Hospital, Inc. | Lipoxin compounds and their use |
| EP1762557B1 (en) | 2000-02-16 | 2011-04-06 | The Brigham And Women's Hospital, Inc. | Aspirin-triggered lipid mediators |
| US7700650B2 (en) | 2000-03-20 | 2010-04-20 | Trustees Of Boston University | Lipoxin analogs and method for the treatment of periodontal disease |
| GB0119583D0 (en) * | 2001-08-10 | 2001-10-03 | Unilever Plc | Cosmetic composition and method of treating skin |
| US6831186B2 (en) | 2001-11-06 | 2004-12-14 | Schering Aktiengesellschft | Lipoxin A4 analogs |
| EP1441715B1 (en) * | 2001-11-06 | 2013-02-27 | The Brigham And Women's Hospital, Inc. | Lipoxins and aspirin-triggered lipoxins and their stable analogs in the treatment of asthma and inflammatory airway diseases |
| WO2003051350A1 (en) * | 2001-12-18 | 2003-06-26 | The Brigham And Women's Hospital | Use of lipoxin analogs to promote cell defense against gram-negative infections |
| US7902257B2 (en) | 2002-04-01 | 2011-03-08 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid |
| US8481772B2 (en) | 2002-04-01 | 2013-07-09 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid derivatives |
| US7759395B2 (en) | 2002-08-12 | 2010-07-20 | The Brigham And Women's Hospital, Inc. | Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma |
| WO2004014835A2 (en) * | 2002-08-12 | 2004-02-19 | Brigham And Women's Hospital | Resolvins: biotemplates for therapeutic interventions |
| WO2004078143A2 (en) * | 2003-03-05 | 2004-09-16 | The Brigham And Women's Hospital Inc. | Methods for identification and uses of anti-inflammatory receptors for eicosapentaenoic acid analogs |
| US20050238589A1 (en) * | 2004-04-14 | 2005-10-27 | Van Dyke Thomas E | Methods and compositions for preventing or treating periodontal diseases |
| BRPI0614693A2 (pt) | 2005-07-29 | 2011-04-12 | Monsanto Technology Llc | desenvolvimento de germoplasma usando segregados de cruzamentos transgênicos |
| WO2007041440A2 (en) * | 2005-10-03 | 2007-04-12 | The Brigham And Women's Hospital, Inc. | Anti-inflammatory actions of neuroprotectin d1/protectin d1 and its natural stereoisomers |
| WO2007061783A1 (en) * | 2005-11-18 | 2007-05-31 | Trustees Of Boston University | Treatment and prevention of bone loss using resolvins |
| CA2650607A1 (en) * | 2006-04-28 | 2007-11-08 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for the treatment of cardiovascular disease |
| EP2049099A1 (en) * | 2006-07-19 | 2009-04-22 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for the treatment of mucositis |
| EP2131833A2 (en) * | 2006-10-26 | 2009-12-16 | Resolvyx Pharmaceuticals, Inc. | Use of resolvins for inhibition of bone loss |
| PE20120395A1 (es) | 2006-12-04 | 2012-05-23 | Bayer Ip Gmbh | Sal de potasio cristalina de analogos de lipoxina a4 |
| WO2008070129A2 (en) * | 2006-12-05 | 2008-06-12 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for the treatment of inflammatory disease |
| EP2207543A2 (en) * | 2007-09-14 | 2010-07-21 | Resolvyx Pharmaceuticals, Inc. | Omega-3 fatty acids, hydroxy polyunsaturated fatty acids, lipoxin compounds, or oxylipin compounds for treating autoimmune diseases or inhibiting immune function |
| US20090118243A1 (en) * | 2007-10-12 | 2009-05-07 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for the treatment of ophthalmic conditions |
| KR101306199B1 (ko) | 2012-01-31 | 2013-09-09 | 부산대학교 산학협력단 | 포스포리파아제 ｄ 억제제를 유효성분으로 포함하는 골다공증 예방 및 치료용 약학적 조성물 |
| WO2014084868A1 (en) | 2012-12-01 | 2014-06-05 | Halliburton Energy Services, Inc. | Protection of electronic devices used with perforating guns |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5411951A (en) | 1984-10-04 | 1995-05-02 | Monsanto Company | Prolonged release of biologically active somatotropin |
| US5650435A (en) | 1991-04-01 | 1997-07-22 | Madara; James L. | Modulation of inflammation related to columnar epithelia |
| EP1657233A1 (en) * | 1993-06-15 | 2006-05-17 | The Brigham & Women's Hospital, Inc. | Lipoxin compounds |
| US5441951A (en) | 1994-06-15 | 1995-08-15 | Brigham & Women's Hospital | Lipoxin compounds |
| AU7215294A (en) | 1993-06-29 | 1995-01-24 | Brigham And Women's Hospital | Modulation of inflammation related to columnar epithelia |
| US5750354A (en) | 1994-03-11 | 1998-05-12 | Brigham And Women's Hospital | Lipoxin transport system and uses therefor |
| HK1043357B (en) * | 1999-03-18 | 2005-12-09 | The Brigham And Women's Hospital, Inc. | LIPOXIN compound and its use |
| WO2000054761A2 (en) * | 1999-03-18 | 2000-09-21 | Brigham And Women's Hospital | Regulation of phospholipase d activity |
| CA2615917C (en) | 1999-03-18 | 2011-10-04 | Brigham And Women's Hospital | Use of lipoxin compounds for inhibiting of tnf-(alpha)initiated neutrophil response |
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2000
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- 2000-03-14 JP JP2000604837A patent/JP4392473B2/ja not_active Expired - Fee Related
- 2000-03-14 AU AU37451/00A patent/AU780114B2/en not_active Ceased
- 2000-03-14 DE DE60044335T patent/DE60044335D1/de not_active Expired - Lifetime
- 2000-03-14 ES ES00916331T patent/ES2344138T3/es not_active Expired - Lifetime
- 2000-03-14 CA CA002365240A patent/CA2365240C/en not_active Expired - Fee Related
- 2000-03-14 EP EP10003005A patent/EP2236140A1/en not_active Withdrawn
- 2000-03-14 US US09/525,157 patent/US6353026B1/en not_active Expired - Lifetime
- 2000-03-14 HK HK02104450.3A patent/HK1043306B/en not_active IP Right Cessation
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- 2000-03-14 CA CA2645558A patent/CA2645558C/en not_active Expired - Fee Related
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2001
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2005
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- 2007-08-13 US US11/837,903 patent/US20080064751A1/en not_active Abandoned
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| EP1162976A2 (en) | 2001-12-19 |
| DE60044335D1 (de) | 2010-06-17 |
| ES2344138T3 (es) | 2010-08-19 |
| US20050187294A1 (en) | 2005-08-25 |
| US20080064751A1 (en) | 2008-03-13 |
| US6353026B1 (en) | 2002-03-05 |
| AU780114B2 (en) | 2005-03-03 |
| HK1043306B (en) | 2010-09-17 |
| AU3745100A (en) | 2000-10-04 |
| WO2000054761A2 (en) | 2000-09-21 |
| CA2645558A1 (en) | 2000-09-21 |
| WO2000054761A9 (en) | 2001-10-25 |
| ATE466582T1 (de) | 2010-05-15 |
| WO2000054761A3 (en) | 2001-03-29 |
| US20020120013A1 (en) | 2002-08-29 |
| HK1043306A1 (en) | 2002-09-13 |
| EP2236140A1 (en) | 2010-10-06 |
| EP1162976B1 (en) | 2010-05-05 |
| CA2645558C (en) | 2012-05-15 |
| US6864288B2 (en) | 2005-03-08 |
| US20020107289A1 (en) | 2002-08-08 |
| CA2365240C (en) | 2009-01-20 |
| CA2365240A1 (en) | 2000-09-21 |
| JP2002539156A (ja) | 2002-11-19 |
| US6927238B2 (en) | 2005-08-09 |
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