JP4238131B2 - 非シアノアクリレートレオロジー改良剤を有する塞栓用組成物 - Google Patents

非シアノアクリレートレオロジー改良剤を有する塞栓用組成物 Download PDF

Info

Publication number
JP4238131B2
JP4238131B2 JP2003521688A JP2003521688A JP4238131B2 JP 4238131 B2 JP4238131 B2 JP 4238131B2 JP 2003521688 A JP2003521688 A JP 2003521688A JP 2003521688 A JP2003521688 A JP 2003521688A JP 4238131 B2 JP4238131 B2 JP 4238131B2
Authority
JP
Japan
Prior art keywords
composition
poly
composition according
cyanoacrylate
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2003521688A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005500414A (ja
JP2005500414A5 (https=
Inventor
スティーブン ポーター,
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Original Assignee
Boston Scientific Ltd Barbados
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Ltd Barbados filed Critical Boston Scientific Ltd Barbados
Publication of JP2005500414A publication Critical patent/JP2005500414A/ja
Publication of JP2005500414A5 publication Critical patent/JP2005500414A5/ja
Application granted granted Critical
Publication of JP4238131B2 publication Critical patent/JP4238131B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10Esters
    • C08F20/26Esters containing oxygen in addition to the carboxy oxygen
    • C08F20/32Esters containing oxygen in addition to the carboxy oxygen containing epoxy radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/36Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Polymerisation Methods In General (AREA)
  • Graft Or Block Polymers (AREA)
  • Dental Preparations (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Surgical Instruments (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
JP2003521688A 2001-08-20 2002-07-09 非シアノアクリレートレオロジー改良剤を有する塞栓用組成物 Expired - Lifetime JP4238131B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/933,316 US7687053B2 (en) 2001-08-20 2001-08-20 Embolic compositions with non-cyanoacrylate rheology modifying agents
PCT/US2002/021532 WO2003016364A1 (en) 2001-08-20 2002-07-09 Embolic compositions with non-cyanoacrylate rheology modifying agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008288650A Division JP2009072610A (ja) 2001-08-20 2008-11-11 非シアノアクリレートレオロジー改良剤を有する塞栓用組成物の使用

Publications (3)

Publication Number Publication Date
JP2005500414A JP2005500414A (ja) 2005-01-06
JP2005500414A5 JP2005500414A5 (https=) 2006-01-05
JP4238131B2 true JP4238131B2 (ja) 2009-03-11

Family

ID=25463727

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2003521688A Expired - Lifetime JP4238131B2 (ja) 2001-08-20 2002-07-09 非シアノアクリレートレオロジー改良剤を有する塞栓用組成物
JP2008288650A Pending JP2009072610A (ja) 2001-08-20 2008-11-11 非シアノアクリレートレオロジー改良剤を有する塞栓用組成物の使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008288650A Pending JP2009072610A (ja) 2001-08-20 2008-11-11 非シアノアクリレートレオロジー改良剤を有する塞栓用組成物の使用

Country Status (7)

Country Link
US (2) US7687053B2 (https=)
EP (1) EP1425319B1 (https=)
JP (2) JP4238131B2 (https=)
AT (1) ATE374219T1 (https=)
CA (1) CA2452505A1 (https=)
DE (1) DE60222680T2 (https=)
WO (1) WO2003016364A1 (https=)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070032853A1 (en) * 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
AU2002316053A1 (en) * 2001-05-01 2002-11-11 A.V. Topchiev Institute Of Petrochemical Synthesis Two-phase, water-absorbent bioadhesive composition
US7687053B2 (en) * 2001-08-20 2010-03-30 Boston Scientific Scimed, Inc. Embolic compositions with non-cyanoacrylate rheology modifying agents
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7094369B2 (en) 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7131997B2 (en) 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
US7053134B2 (en) 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
US7459142B2 (en) * 2002-06-06 2008-12-02 Micro Therapeutics, Inc. High viscosity embolizing compositions comprising prepolymers
US8425549B2 (en) 2002-07-23 2013-04-23 Reverse Medical Corporation Systems and methods for removing obstructive matter from body lumens and treating vascular defects
US7449236B2 (en) 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7588825B2 (en) 2002-10-23 2009-09-15 Boston Scientific Scimed, Inc. Embolic compositions
DE602004015574D1 (de) * 2003-02-26 2008-09-18 Micro Therapeutics Inc Emboliezusammensetzungen enthaltend pyrogenes silicium
US20050025707A1 (en) * 2003-02-27 2005-02-03 Patterson William R. Fumed silica embolic compositions
WO2005067990A1 (en) * 2004-01-07 2005-07-28 Boston Scientific Santa Rosa Corporation Methods, compositions, and devices for embolizing body lumens
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US9675476B2 (en) 2004-05-25 2017-06-13 Covidien Lp Vascular stenting for aneurysms
AU2010236494B2 (en) 2004-05-25 2013-05-30 Covidien Lp Vascular stenting for aneurysms
JP2008502378A (ja) 2004-05-25 2008-01-31 チェストナット メディカル テクノロジーズ インコーポレイテッド フレキシブルな血管閉鎖デバイス
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US20070078207A1 (en) * 2005-09-30 2007-04-05 Jonn Jerry Y Stabilizer cyanoacrylate formulations
US7501179B2 (en) 2005-12-21 2009-03-10 Boston Scientific Scimed, Inc. Block copolymer particles
US20070184087A1 (en) * 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
US8152833B2 (en) 2006-02-22 2012-04-10 Tyco Healthcare Group Lp Embolic protection systems having radiopaque filter mesh
WO2007134239A2 (en) * 2006-05-12 2007-11-22 Cordis Corporation Balloon expandable bioabsorbable drug eluting flexible stent
EP2020967B1 (en) * 2006-05-12 2020-09-23 Cardinal Health Switzerland 515 GmbH Baloon expandable bioabsorbable drug eluting stent
CN101917927A (zh) * 2007-11-12 2010-12-15 维勒医学有限公司 医用级氰基丙烯酸酯的单瓶制剂
US7972373B2 (en) * 2007-12-19 2011-07-05 Advanced Technologies And Regenerative Medicine, Llc Balloon expandable bioabsorbable stent with a single stress concentration region interconnecting adjacent struts
JP5610542B2 (ja) 2008-04-21 2014-10-22 コヴィディエン リミテッド パートナーシップ ブレードボール塞栓装置および送達システム
WO2009140437A1 (en) 2008-05-13 2009-11-19 Nfocus Neuromedical, Inc. Braid implant delivery systems
US10143455B2 (en) 2011-07-20 2018-12-04 Covidien LLP Enhanced ultrasound visualization of intravascular devices
EP2398402B1 (en) 2009-02-20 2016-04-20 Covidien LP Devices for venous occlusion for the treatment of venous insufficiency
US8409269B2 (en) 2009-12-21 2013-04-02 Covidien Lp Procedures for vascular occlusion
US8998947B2 (en) 2010-09-10 2015-04-07 Medina Medical, Inc. Devices and methods for the treatment of vascular defects
JP6087281B2 (ja) 2010-09-10 2017-03-01 メディナ メディカル,インコーポレイテッド 血管異常を治療するデバイス及び方法
CN103237526B (zh) 2010-12-06 2015-12-02 科维蒂恩有限合伙公司 脉管重塑装置
US20120245674A1 (en) 2011-03-25 2012-09-27 Tyco Healthcare Group Lp Vascular remodeling device
US10196543B2 (en) 2011-03-31 2019-02-05 Adhezion Biomedical, Llc Fast bonding hair/eyelash extension adhesive compositions based on medical grade high viscosity cyanoacrylates
BR112013028603A2 (pt) 2011-05-11 2017-01-17 Covidien Lp dispositivo de remodelagem vascular
WO2013049448A1 (en) 2011-09-29 2013-04-04 Covidien Lp Vascular remodeling device
US9072620B2 (en) 2011-11-04 2015-07-07 Covidien Lp Protuberant aneurysm bridging device deployment method
US9011480B2 (en) 2012-01-20 2015-04-21 Covidien Lp Aneurysm treatment coils
US8808620B1 (en) 2012-02-22 2014-08-19 Sapheon, Inc. Sterilization process design for a medical adhesive
US9452070B2 (en) 2012-10-31 2016-09-27 Covidien Lp Methods and systems for increasing a density of a region of a vascular device
CN108354645B (zh) 2012-11-13 2026-03-13 柯惠有限合伙公司 封堵装置
US10076336B2 (en) 2013-03-15 2018-09-18 Covidien Lp Delivery and detachment mechanisms for vascular implants
US10736758B2 (en) 2013-03-15 2020-08-11 Covidien Occlusive device
WO2015073704A1 (en) 2013-11-13 2015-05-21 Covidien Lp Galvanically assisted attachment of medical devices to thrombus
CN105899136A (zh) * 2014-01-07 2016-08-24 柯惠有限合伙公司 包含非聚结性不透射线的纳米颗粒的氰基丙烯酸酯组合物
CN106604751A (zh) * 2014-04-11 2017-04-26 柯惠Lp公司 带标记的手术器械及其制造方法
US9713475B2 (en) 2014-04-18 2017-07-25 Covidien Lp Embolic medical devices
US9814466B2 (en) 2014-08-08 2017-11-14 Covidien Lp Electrolytic and mechanical detachment for implant delivery systems
US10314593B2 (en) 2015-09-23 2019-06-11 Covidien Lp Occlusive devices
US10478194B2 (en) 2015-09-23 2019-11-19 Covidien Lp Occlusive devices
WO2017165833A1 (en) 2016-03-24 2017-09-28 Covidien Lp Thin wall constructions for vascular flow diversion
US10828037B2 (en) 2016-06-27 2020-11-10 Covidien Lp Electrolytic detachment with fluid electrical connection
US10828039B2 (en) 2016-06-27 2020-11-10 Covidien Lp Electrolytic detachment for implantable devices
US11051822B2 (en) 2016-06-28 2021-07-06 Covidien Lp Implant detachment with thermal activation
US10478195B2 (en) 2016-08-04 2019-11-19 Covidien Lp Devices, systems, and methods for the treatment of vascular defects
US10576099B2 (en) 2016-10-21 2020-03-03 Covidien Lp Injectable scaffold for treatment of intracranial aneurysms and related technology
US10675036B2 (en) 2017-08-22 2020-06-09 Covidien Lp Devices, systems, and methods for the treatment of vascular defects
US11065136B2 (en) 2018-02-08 2021-07-20 Covidien Lp Vascular expandable devices
US11065009B2 (en) 2018-02-08 2021-07-20 Covidien Lp Vascular expandable devices
US10912569B2 (en) 2018-08-22 2021-02-09 Covidien Lp Aneurysm treatment coils and associated systems and methods of use
US10905432B2 (en) 2018-08-22 2021-02-02 Covidien Lp Aneurysm treatment coils and associated systems and methods of use
WO2020131976A2 (en) 2018-12-17 2020-06-25 Covidien Lp Devices, systems, and methods for the treatment of vascular defects
US11498165B2 (en) 2019-11-04 2022-11-15 Covidien Lp Systems and methods for treating aneurysms
US11931041B2 (en) 2020-05-12 2024-03-19 Covidien Lp Devices, systems, and methods for the treatment of vascular defects
CN112870428B (zh) * 2021-01-21 2022-05-27 北京冠合医疗科技有限公司 一种显影清晰的栓塞材料及其制备方法
US12364793B2 (en) 2021-03-16 2025-07-22 Covidien Lp Injectable biopolymer compositions and associated systems and methods
CN115364272B (zh) * 2022-09-09 2023-08-08 江西博恩锐尔生物科技有限公司 柔软度可调的血管栓塞剂及其制备方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE616638A (https=) 1961-04-20
US3896077A (en) * 1966-10-10 1975-07-22 Fred Leonard Underwater adhesive
US3728375A (en) 1971-05-12 1973-04-17 Eastman Kodak Co Cyanoacrylate adhesive compositions
US4406878A (en) * 1978-08-02 1983-09-27 Eastman Kodak Company Iodinated contrast agent for radiography
DE2850918A1 (de) * 1978-11-24 1980-06-04 Bayer Ag Roentgenopake dentalwerkstoffe auf basis von organischen kunststoffen in pastoeser form
IL63876A0 (en) 1980-10-20 1981-12-31 Population Res Inc Radiopaque cyanoacrylates
US4713235A (en) 1981-05-26 1987-12-15 Crx Medical, Inc. Radiopaque cyanoacrylates
CA1225585A (en) * 1983-06-30 1987-08-18 Maria T. Litvinova Composition for embolization of blood vessels
US5322499A (en) 1985-09-20 1994-06-21 Liprie Sam F Continuous sheated low dose radioactive core adapted for cutting into short sealed segments
GB8729140D0 (en) 1987-12-14 1988-01-27 Lingner & Fischer Gmbh Adhesive
US5326552A (en) * 1992-12-17 1994-07-05 Sterling Winthrop Inc. Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants
ES2152990T3 (es) 1993-09-09 2001-02-16 Schering Ag Principios activos y microparticulas que contienen gases.
US5795331A (en) 1994-01-24 1998-08-18 Micro Therapeutics, Inc. Balloon catheter for occluding aneurysms of branch vessels
DE69503844T2 (de) 1994-06-08 1999-04-22 Taoka Chemical Co., Ltd., Osaka Klebemittelzusammensetzung auf Alphacyanoacrylat Basis
US5739205A (en) 1994-06-08 1998-04-14 Taoka Chemical Company, Limited α-cyanoacrylate adhesive composition
JPH08259899A (ja) * 1995-03-23 1996-10-08 Three Bond Co Ltd シアノアクリレート系接着剤組成物
US5795922A (en) * 1995-06-06 1998-08-18 Clemson University Bone cement composistion containing microencapsulated radiopacifier and method of making same
US5591195A (en) 1995-10-30 1997-01-07 Taheri; Syde Apparatus and method for engrafting a blood vessel
US5882334A (en) 1995-12-04 1999-03-16 Target Therapeutics, Inc. Balloon/delivery catheter assembly with adjustable balloon positioning
US5702361A (en) 1996-01-31 1997-12-30 Micro Therapeutics, Inc. Method for embolizing blood vessels
US5817343A (en) 1996-05-14 1998-10-06 Alkermes, Inc. Method for fabricating polymer-based controlled-release devices
AU2745497A (en) * 1996-05-31 1998-01-05 Micro Therapeutics, Inc. Compositions for use in embolizing blood vessels
US5925683A (en) * 1996-10-17 1999-07-20 Target Therapeutics, Inc. Liquid embolic agents
US6020004A (en) 1997-04-17 2000-02-01 Amgen Inc. Biodegradable microparticles for the sustained delivery of therapeutic drugs
US6037366A (en) * 1997-09-11 2000-03-14 Prohold Medical Technologies, Inc. Composition for creating vascular occlusions
US6476069B2 (en) * 1997-09-11 2002-11-05 Provasis Therapeutics Inc. Compositions for creating embolic agents and uses thereof
US6538026B1 (en) 1997-09-11 2003-03-25 Provasis Therapeutics, Inc. Compositions useful for remodeling body spaces
US6476070B2 (en) * 1997-09-11 2002-11-05 Provasis Therapeutics Inc. Compositions useful for remodeling body spaces
US6015541A (en) 1997-11-03 2000-01-18 Micro Therapeutics, Inc. Radioactive embolizing compositions
US6015424A (en) 1998-04-28 2000-01-18 Microvention, Inc. Apparatus and method for vascular embolization
US6203779B1 (en) * 1999-03-19 2001-03-20 Charlie Ricci Methods for treating endoleaks during endovascular repair of abdominal aortic aneurysms
US7687053B2 (en) * 2001-08-20 2010-03-30 Boston Scientific Scimed, Inc. Embolic compositions with non-cyanoacrylate rheology modifying agents

Also Published As

Publication number Publication date
EP1425319B1 (en) 2007-09-26
EP1425319A1 (en) 2004-06-09
JP2005500414A (ja) 2005-01-06
DE60222680T2 (de) 2008-06-12
DE60222680D1 (de) 2007-11-08
WO2003016364A1 (en) 2003-02-27
JP2009072610A (ja) 2009-04-09
CA2452505A1 (en) 2003-02-27
ATE374219T1 (de) 2007-10-15
US20030039696A1 (en) 2003-02-27
US20100144895A1 (en) 2010-06-10
US7687053B2 (en) 2010-03-30

Similar Documents

Publication Publication Date Title
JP4238131B2 (ja) 非シアノアクリレートレオロジー改良剤を有する塞栓用組成物
JP6710746B2 (ja) ポリマー治療組成物
CA2481365C (en) Occlusive composition comprising a poly (2-cyanoacrylate) monomer
CA2360533C (en) Compositions comprising cyanoacrylates and an opacifying agent
US20040197302A1 (en) Prepolymeric materials for site specific delivery to the body
JP2003534406A (ja) 重合可能な組成物および使用法

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20041025

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20041025

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050630

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050630

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20071116

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20071204

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20080229

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20080307

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080403

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080513

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20080811

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20080821

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20081111

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20081209

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20081219

R150 Certificate of patent or registration of utility model

Ref document number: 4238131

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20111226

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20111226

Year of fee payment: 3

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: R3D02

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: R3D04

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20111226

Year of fee payment: 3

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: R3D04

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20111226

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121226

Year of fee payment: 4

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121226

Year of fee payment: 4

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20131226

Year of fee payment: 5

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313117

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R371 Transfer withdrawn

Free format text: JAPANESE INTERMEDIATE CODE: R371

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313117

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313117

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R371 Transfer withdrawn

Free format text: JAPANESE INTERMEDIATE CODE: R371

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313117

R360 Written notification for declining of transfer of rights

Free format text: JAPANESE INTERMEDIATE CODE: R360

R360 Written notification for declining of transfer of rights

Free format text: JAPANESE INTERMEDIATE CODE: R360

R371 Transfer withdrawn

Free format text: JAPANESE INTERMEDIATE CODE: R371

R360 Written notification for declining of transfer of rights

Free format text: JAPANESE INTERMEDIATE CODE: R360

R360 Written notification for declining of transfer of rights

Free format text: JAPANESE INTERMEDIATE CODE: R360

R371 Transfer withdrawn

Free format text: JAPANESE INTERMEDIATE CODE: R371

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term