JP4198195B2 - 負鎖rnaウイルスの、それらの遺伝子の再配列による弱毒化およびそれらの使用 - Google Patents

負鎖rnaウイルスの、それらの遺伝子の再配列による弱毒化およびそれらの使用 Download PDF

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JP4198195B2
JP4198195B2 JP54828198A JP54828198A JP4198195B2 JP 4198195 B2 JP4198195 B2 JP 4198195B2 JP 54828198 A JP54828198 A JP 54828198A JP 54828198 A JP54828198 A JP 54828198A JP 4198195 B2 JP4198195 B2 JP 4198195B2
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JP2001527409A5 (cg-RX-API-DMAC7.html
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ワーツ,ゲイル
アンドリュー ボール,エル
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ザ ユーエイビー リサーチ ファンデイション
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
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    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20241Use of virus, viral particle or viral elements as a vector
    • C12N2760/20243Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20261Methods of inactivation or attenuation

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP54828198A 1997-05-02 1998-05-01 負鎖rnaウイルスの、それらの遺伝子の再配列による弱毒化およびそれらの使用 Expired - Fee Related JP4198195B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4547197P 1997-05-02 1997-05-02
US60/045,471 1997-05-02
PCT/US1998/008938 WO1998050529A1 (en) 1997-05-02 1998-05-01 Attenuation of negative stranded rna viruses by rearrangement of their genes and uses thereof

Related Child Applications (1)

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JP2007242099A Division JP2008022859A (ja) 1997-05-02 2007-09-19 遺伝子の再配列による(−)鎖rnaウイルスの弱毒化およびそれらの使用法

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JP2001527409A JP2001527409A (ja) 2001-12-25
JP2001527409A5 JP2001527409A5 (cg-RX-API-DMAC7.html) 2005-11-24
JP4198195B2 true JP4198195B2 (ja) 2008-12-17

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JP54828198A Expired - Fee Related JP4198195B2 (ja) 1997-05-02 1998-05-01 負鎖rnaウイルスの、それらの遺伝子の再配列による弱毒化およびそれらの使用
JP2007242099A Pending JP2008022859A (ja) 1997-05-02 2007-09-19 遺伝子の再配列による(−)鎖rnaウイルスの弱毒化およびそれらの使用法

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US (1) US6136585A (cg-RX-API-DMAC7.html)
EP (1) EP1005535B1 (cg-RX-API-DMAC7.html)
JP (2) JP4198195B2 (cg-RX-API-DMAC7.html)
AU (1) AU739597B2 (cg-RX-API-DMAC7.html)
CA (1) CA2288434C (cg-RX-API-DMAC7.html)
WO (1) WO1998050529A1 (cg-RX-API-DMAC7.html)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596529B1 (en) * 1997-05-02 2003-07-22 Uab Research Foundation Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof
AU739597B2 (en) * 1997-05-02 2001-10-18 Uab Research Foundation, The Attenuation of negative stranded RNA viruses by rearrangement of their genes and uses thereof
US20030082209A1 (en) * 2000-07-05 2003-05-01 Skiadopoulos Mario H. Attenuated human-bovine chimeric parainfluenza virus (PIV) vaccines
EP1137759A2 (en) * 1998-12-07 2001-10-04 U.S. Medical Research Institute of Infectious Diseases Live attenuated venezuelan equine encephalitis vaccine
US6764685B1 (en) * 2000-03-21 2004-07-20 Medimmune Vaccines, Inc. Recombinant parainfluenza virus expression systems and vaccines
IL163646A0 (en) * 2002-02-21 2005-12-18 Vironovative Bv Recombinant parainfluenza virus expression systemsand vaccines comprising heterologous antigens derived from metapneumovirus
CA2477037C (en) * 2002-02-21 2014-12-09 Mount Sinai School Of Medicine Recombinant negative strand virus rna expression systems and vaccines
MXPA05013141A (es) 2003-06-09 2006-03-17 Wyeth Corp Metodo mejorado para la recuperacion de arn virus de cadena negativa, no segmentados, a partir de adnc.
EP1756287B1 (en) * 2004-04-09 2015-02-25 Wyeth LLC Synergistic attenuation of vesicular stomatitis virus, vectors thereof and immunogenic compositions thereof
US8097419B2 (en) 2006-09-12 2012-01-17 Longhorn Vaccines & Diagnostics Llc Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009
US8652782B2 (en) 2006-09-12 2014-02-18 Longhorn Vaccines & Diagnostics, Llc Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids
US8080645B2 (en) 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
US9481912B2 (en) 2006-09-12 2016-11-01 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and identifying nucleic acid sequences in biological samples
CA2921063C (en) 2006-09-15 2020-01-28 Ottawa Hospital Research Institute Oncolytic rhabdovirus
EP2069485A4 (en) * 2007-07-13 2011-05-25 Medimmune Llc PREPARATION OF NEGATIVE STRAND RNA VIRUSES BY ELECTROPORATION
US9683256B2 (en) 2007-10-01 2017-06-20 Longhorn Vaccines And Diagnostics, Llc Biological specimen collection and transport system
US11041215B2 (en) 2007-08-24 2021-06-22 Longhorn Vaccines And Diagnostics, Llc PCR ready compositions and methods for detecting and identifying nucleic acid sequences
US10004799B2 (en) 2007-08-27 2018-06-26 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
CA2697373C (en) * 2007-08-27 2019-05-21 Longhorn Vaccines & Diagnostics, Llc Immunogenic compositions and methods
WO2009085355A2 (en) 2007-10-01 2009-07-09 Longhorn Vaccines & Diagnostics Llc Biological specimen collection and transport system and methods of use
US11041216B2 (en) 2007-10-01 2021-06-22 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples
JP5045416B2 (ja) * 2007-12-17 2012-10-10 富士通株式会社 光導波路素子およびそれを用いた光学装置
US20090162321A1 (en) * 2007-12-20 2009-06-25 Wyeth Methods for packaging propagation-defective vesicular stomatitis virus vectors using a stable cell line that expresses g protein
US20090175900A1 (en) * 2007-12-20 2009-07-09 Wyeth Methods for packaging propagation-defective vesicular stomatitis virus vectors
CA3207612A1 (en) 2012-01-26 2013-08-01 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
EP3294448A4 (en) 2015-05-14 2018-12-12 Longhorn Vaccines and Diagnostics, LLC Rapid methods for the extraction of nucleic acids from biological samples
US12485166B2 (en) 2020-02-06 2025-12-02 Longhorn Vaccines And Diagnostics, Llc Vaccines for the treatment and prevention of zoonotic infections
US12403189B2 (en) 2020-10-20 2025-09-02 Longhorn Vaccines And Diagnostics, Llc Immunogenic antigens

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9710363A (pt) * 1996-07-15 2000-01-11 Us Gov Health & Human Serv "vìrus sincicial respirátorio recombinante infeccioso isolado, partìcula do mesmo, processos para estimular o sistema imunológico de um indivìduo para induzir proteção contra o vìrus sincicial respiratório e para produzir uma partìcula de vìrus sincicial respiratório recombinante, vacina para induzir proteção contra o vìrus sincicial respiratório recombinante composição e ceta de vìrus sincicial respiratório recombinante"
AU739597B2 (en) * 1997-05-02 2001-10-18 Uab Research Foundation, The Attenuation of negative stranded RNA viruses by rearrangement of their genes and uses thereof

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Publication number Publication date
AU739597B2 (en) 2001-10-18
EP1005535A1 (en) 2000-06-07
EP1005535A4 (en) 2002-07-17
CA2288434C (en) 2012-01-03
EP1005535B1 (en) 2015-11-11
AU7278198A (en) 1998-11-27
JP2008022859A (ja) 2008-02-07
US6136585A (en) 2000-10-24
JP2001527409A (ja) 2001-12-25
WO1998050529A1 (en) 1998-11-12
CA2288434A1 (en) 1998-11-12

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