JP4183800B2 - Disease prevention / treatment method for organisms other than human body, information storage medium used in this method, and information-stored ceramic body - Google Patents

Description

【００３９】
表１から明らかなように、バキュロウイルス強制感染後、感染処理群の対照区（第４試験区）のエビは１０日以内に壊滅的な斃死をみたのに対し、本発明試験区の斃死率は３０〜４０％であり、これらの間に有意な差がみられた（ｐ＜０．０５）。また、無処理の対照区（健全エビ）の斃死率が２７％程度であり試験区と有意な差がみられなかった（ｐ＜０．０５）。すなわち、強制感染群も、本発明の３種の処理によってバキュロウイルスによる急性ウイルス血症を制御し、健全エビとほぼ同じ生残を示したものである。
なお、無処理の対照区（健全エビ）が２７％程度斃死したのは予備水槽から試験水槽への移槽によるストレス及び狭い試験水槽のストレスによるものである。
この試験から、クルマエビ体内に侵入したバキュロウイルスが、環境飼育水からバキュロウイルスの活性逆情報と思われる情報を受け、またはバキュロウイルスの活性逆情報と思われる情報を経口的に受け、その活性が低下したことが判明した。しかも、従来の薬剤を使用せずに、情報のみでバキュロウイルスの活性が制御されるという事実が明らかになった。
【００４０】
（実施例２）バキュロウイルス逆情報によるバキュロウイルスの活性制御作用−２
試験方法：平均体重１１．５ｇのエビを用い、実施例１と同じ処理を行い下記の５つの試験区を設定した。
第１試験区はバキュロウイルス逆転写記憶水（逆転水）を飼育槽の飼育水に使用した群
第２試験区は逆転写記憶水で作成したセラミックを用いて処理した飼育水を使用し、且つ、バキュロウイルス逆転写記憶水（逆転水）を噴霧処理の配合飼料ベレットを投与した群
第３試験区は直線磁場２にバキュロウイルス記憶済みの磁気記憶媒体を配置し、湾曲磁場３の水を飼育水槽にパイプを介してが常時循環通過させる群
第４試験区はバキュロウイルスを強制感染させた対照群
第５試験区は無処理の健全エビの対照群である。
【００４１】
試験結果：本発明試験区及び対照区におけるバキュロウイルス強制感染後のクルマエビの累積斃死尾数、累積斃死率と各日朝の残餌率を表２に示した。
【表２】

【００４２】
表２から明らかなように、バキュロウイルス強制感染後、感染処理対照区は９日で１００％斃死したのに対し、本発明による試験区３区ともに３５％程度であり、対照区との間に有意な差がみられた（ｐ＜０．０１）。試験区３の結果から、磁化記憶水を使用しなくても、飼育環境水に常時逆転処理を行えばバキュロウイルスの活性を制御できることがわかった。この処理速度は飼育水量１回転／１２時間以上である。また、非感染の無処理対照区と本発明試験区との斃死率に有意差はみられなかった。
【００４３】
（実施例３）生体防御機能向上情報によるバキュロウイルス活性の制御作用
試験方法：平均体重約１２．０ｇのエビを用い、実施例１と全く同様な処理を行い下記の５つの試験区を設置した。
対照区の２つの区は前記と同様に強制感染処理群との未処理健全群である。
本発明の３つの試験区はバキュロウイルスの逆情報ではなく、生体防御機能向上させる抗体の正情報を利用する区である。あらかじめ、１０数尾を別途飼育し、ペプチドグリカン（ＰＧ）を適正量、適正期間投与する。この処置によりエビの生体防御機能が増強することが既に確認されている。本試験では、これらのエビ数尾から血液を採取し、遠心分離処理液から磁気装置を用いて記憶水ならびに磁気記憶媒体に転写した。
第１試験区はこの記憶水を噴霧処理した飼料ペレットをクルマエビに投与した群
第２試験区はこの記憶水を用いて作成したセラミックを水槽に浸漬して飼育環境水を処理した群
第３試験区は血液の情報を記憶させた磁気記憶媒体をいったん逆転再転写して新たな磁気記憶媒体を作り、それを磁気装置の直線磁場Ｎ極側に配置して、湾曲磁場４の水を飼育水槽にパイプを介してが常時循環通過させる群。このパイプを通過した飼育環境水は生体防御機能増強の血液情報（正）→逆転（負）→再逆転（正）となる。
第４試験区はバキュロウイルスを強制感染させた対照群
第５試験区は無処理の健全エビの対照群である。
【００４４】
試験結果：本発明試験区及び対照区におけるバキュロウイルス強制感染後のクルマエビの累積斃死尾数、累積斃死率と各日朝の残餌率を表３に示した。
【表３】

【００４５】
表３に示すように、無処理対照区は１０日後の斃死率が３６．７％にとどまったのに対し、強制感染対照区は９６．７％が斃死した。一方、餌に生体防御情報記憶水を噴霧処理した試験区１、同記憶水を用いて作成したセラミックにて飼育水を処理した試験区２、及び、装置を用いて常時飼育水を循環させた試験区３の斃死率は各々４０．０％、３３．３％、及び３３．３％であり、強制感染対照区と有意な差が認められた（ｐ＜０．０５）。
同時に無処理対照区とほぼ同率の斃死率であった。
【００４６】
（実施例４）バキュロウイルス逆情報と生体防御機能正情報併用によるバキュロウイルス活性制御作用−その１
試験方法：平均体重約１２．５ｇのエビを用い、実施例１と全く同じ処理を行い５つの試験区を設定した。
本発明試験区は第１試験区〜第４試験区の４つの区で、いずれも、バキュロウイルスの情報を逆転写した記憶媒体と生体防御機能を増強させた血液からその情報を記憶させた記憶媒体を併用した区である。対照区は強制感染処理区のみである。
第１試験区はバキュロウイルス逆情報と生体防御情報の両者を記憶させた記憶水でペレットに噴霧添加処理し給餌する群
第２試験区は第１試験区と同じ２種の情報の記憶水で作成したセラミックを用い、飼育環境水を処理する群
第３試験区は第１試験区と第２試験区の併用区である。
第４試験区は飼育環境水を、２種の情報の記憶媒体を設置した磁気装置に常時循環通過させて、バキュロウイルス逆情報と生体防御情報を飼育環境水に投与する群である。
第５試験区はバキュロウイルスを強制感染させた対照群
【００４７】
試験結果：本発明試験区及び対照区におけるバキュロウイルス感染後の累積斃死尾数、累積斃死率及び残餌率（各朝）を表４に示した。
【表４】

【００４８】
表４に示すように、バキュロウイルス強制感染後、対照区は１０日後には９０％以上が斃死した。これに対し、ウイルス性と生体防御の２情報を与えられた餌区とセラミック区はほぼ３０％の斃死率、餌とセラミック併用区では２０％以下の斃死となった。さらに、２情報を磁気装置を使用して飼育環境水を処理した区は１５％以下の斃死率となった。試験区はすべて、対照区と比べ斃死率において有意な差が認められた（ｐ＜０．０５）。
【００４９】
（実施例５）バキュロウイルス逆情報と生体防御機能増強正情報併用によるバキュロウイルス活性制御作用−その２
試験方法：平均体重約１４．０ｇのエビを用い、実施例１と同様の処理を行い５つの試験区を設定した。第１試験区〜第４試験区は本発明２よる試験区であり、対照区は強制感染処理区のみである。
第１試験区はバキュロウイルスの逆情報と生体防御機能増強正情報を併用して作成したセラミックを飼育環境水に使用すると同時に、この両情報記憶水でペレット処理し投与する群（実施例４の試験区３と同じ）
第２試験区はバキュロウイルス逆情報と生体防御機能増強正情報を記憶した磁気記憶媒体とパイプを磁気装置に設置し、常時外気を送りこんで、飼育環境水を曝気する区である。
第３試験区は第２試験区の変形で、送気パイプの中間に水箱をおきその箱の水を曝気した後の空気を飼育環境水に送気して再曝気する区である。なお、この水箱には情報記憶用磁気記憶媒体水を使用した。
第４試験区は第１試験区と第３試験区の併用、すなわち餌処理、セラミックによる飼育環境水処理及び情報記憶用磁気記憶媒体水経由の曝気による飼育環境水処理を行う区である。
【００５０】
試験結果：本発明試験区及び対照区におけるバキュロウイルス感染後の累積斃死尾数、累積斃死率及び残餌率（各朝）を表５に示した。
【表５】

【００５１】
表５に示すように、バキュロウイルス強制感染後、感染対照区は１０日以内に９０％以上が斃死したのに対し、餌処理とセラミックによる飼育環境水処理を併用した第１試験区では２０％の斃死率であった。曝気により飼育環境水を処理した第２試験区では２５％以下の斃死率であった。さらに、送気パイプの中間に人工生体水を設置した第３試験区では１０％の斃死率であった。また、餌、セラミック及び情報記憶用磁化水使用の曝気を併用した４試験区では１５％以下の斃死率であった。これら本発明試験区のすべてが対照区と比べ、斃死率において有意な差がみられた（ｐ＜０．０５）。
【００５２】
（実施例６）生体防御機能増強剤情報によるバキュロウイルスの活性制御作用
試験方法：平均体重約１３．０ｇのエビを用い、実施例１と全く同様な処理を行い下記の５つの試験区を設定した。対照区は強制感染処理群と未処理健全群の２区である。第１試験区〜第３試験区は本発明の試験区であり、いずれも、生体防御機能増強剤ペプチドグリカンの情報を直接正転写で記憶させたものを利用する区である。また、対照区は強制感染処理群と未処理健全群の２区である。
第１試験区は磁気装置、磁気記憶媒体及び磁気記憶水を使用してペプチドグリカン情報転写液を調整し、それをもってペレットを処理し投与する区
第２試験区はペプチドグリカン情報記憶液を用いてセラミックスを作成し、それを使用して飼育環境水を処理する区
第３試験区はペプチドグリカン情報記憶済みの磁気記憶媒体を配置した磁気装置にパイプを設置し外気を人口生体水通過後飼育環境水に通気する区である。
第４試験区はバキュロウイルスを強制感染させた対照群
第５試験区は無処理の健全エビの対照群である。
【００５３】
試験結果：本発明試験区及び対照区におけるバキュロウイルス感染後の累積斃死尾数、累積斃死率及び残餌率（各朝）を表６に示した。
【表６】

【００５４】
表６に示すように、バキュロウイルス強制感染対照区は９日後に全滅した。無処理健全区は３０％が斃死しその間に有意な差がみられた。試験区は何れも５０％程度の斃死率となり感染対照区と有意な差がみられたが、無処理健全区とは有意な差がみられなかった。
【００５５】
上記の説明では主としてエビの養殖におけるバキュロウイルス感染症に本発明を応用した実施例を示したが、本発明はこれに限定されるものではなく、ブリのイリドウイルス感染症及び連鎖球菌症、ヒラメのヘルペスウイルス感染症、アユのシュードモナス病及び冷水症、アワビのウイルス性筋萎縮症、ブタのマイコプラズマ症（ＳＥＰ）、オーエスキー病、生殖器、呼吸器症候群、ニワトリの大腸菌症、マイコプラズマ症（ＣＤＲ）などの予防や種々の生物のいろいろな疾病の治療に広く応用することができるものである。
【００５６】
【効果】
本発明はウイルス等の病原体（抗原）の活性を抑制するための、抗原の逆情報波動、並びに、生物の免疫機能を増強させる抗体の正情報波動を利用して疾病を予防し、治療するので化学薬剤の直接投与を一切用いずに生物を健全に育成することができる。従って、化学薬剤の使用による公衆衛生上の問題が解消される。
【００５７】
また、実験例から明らかなように、ウイルスに強制感染させ、放置しておけば数日で１００％死滅してしまう生物群が、本発明の方法によれば感染していない生物群と同等の生存率を示すところから、その疾病予防・治療効果は絶大であり、これまでに例を見ないものである。
従って、生物、特に魚介甲殻類の養殖において、著しい経済効果がもたらされる。
【００５８】
抗原や抗体の情報波動を記憶させた磁気記憶媒体を使用する場合は、有害な抗原を直接扱う必要がないので安全であり、また、記憶済みの磁気記憶媒体を反復して使用できるので効率がよい。
【図面の簡単な説明】
【図１】 本発明の方法に使用される磁気装置の概略構成図
【図２】 本発明の方法の実施例を示す概略図
【図３】 抗原の情報を記憶させた磁気記憶媒体の生成工程説明図
【図４】 本発明の方法の他の実施例を示す概略図
【図５】 本発明の方法に使用される他の磁気装置の概略構成図
【符号の説明】
１、１ａ、１ｂ…磁石
２…直線磁場
３…湾曲磁場
４、４ａ…抗原
４ｂ…抗原の情報を記憶させた磁気記憶媒体
５…媒体
６…抗体
７…曲線磁場
８…外側曲線磁場
９…枠[0001]
[Industrial application fields]
The present invention relates to a disease prevention / treatment method for living organisms that promotes the activity by treating information from antigens and antibodies obtained through magnetism, and an information storage medium and information-stored ceramic body used in this method.
[0002]
[Prior art]
In recent years, with the development of seafood crustacean aquaculture, viral and bacterial diseases frequently occur, causing serious damage. In the case of viral diseases, there has been significant economic damage, particularly due to iridovirus infections such as red sea bream, sea bream, amberjack, yellowtail, and shrimp baculovirus infections, but no therapeutic drugs have been developed yet. . Regarding bacterial infections, the economic damages caused by nodular diseases, vibrio infections, and edwarda infections are significant. Various antibiotics and synthetic antibacterial agents have been used as therapeutic agents for these bacterial diseases, but in recent years, resistant bacteria have emerged against antibiotics, and a sufficient therapeutic effect cannot be obtained. In addition, since there is a problem in public health due to the residual of the drug used in fish and shellfish in the body, prevention of epidemics that does not depend on chemotherapy is strongly desired.
[0003]
On the other hand, techniques for increasing the immune function of seafood shellfish to reduce damage are already known, and some have been put into practical use. As immune function enhancers, there are polysaccharides such as peptide glucan derived from bifidobacteria and β-1,3-glucan derived from mushrooms, and development is ongoing. However, since these drugs administer the drug directly to the organism, the drug is consumed each time, and the cost is high. In addition, direct administration of a drug does not only provide a sufficient preventive / therapeutic effect, but also has many adverse effects caused by abuse or misuse.
[0004]
[Problems to be solved by the invention]
As described above, many diseases have occurred in the cultivation of seafood shellfish, and the damage caused by this has reached 25 billion yen in Japan alone. Not only economic damage, but also sound management based on aquaculture technology such as seed production, compound feed, breeding management and aquaculture facility equipment that has been accumulated over many years due to illness greatly fluctuated from the bottom, even the survival of the industry It is the current time that is in danger. The reasons for this include the emergence of resistant bacteria due to misuse of drugs, the development of chemical drugs and vaccines that cannot keep up with the occurrence of new viruses, the stress of environmental degradation and high-density production, and the decline in immune function.
[0005]
In terms of the growth of seafood shellfish, cultivating fisheries and marine ranch projects are being promoted as national measures aimed at restoring depleted resources. However, there have been frequent cases of artificial hatching mass-produced seedlings and discharge juveniles that form the basis of this project that have been infected with viruses and bacteria before release. If even a small part of a large number of juveniles is infected, it is impossible to discharge the whole because it is functionally difficult to perform biopsy and identification of the infection, and it will be discarded. This is because, compared to aquaculture that can be managed after the fact, it cannot be managed by breeding, and it is not allowed to release the plague to nature.
[0006]
Therefore, the first object of the present invention is to reduce the antigenic activity of living organisms and enhance immune function without direct administration of drugs or vaccines, thereby to make living organisms, particularly seafood crustaceans healthy and safe. It is to provide a method for preventing and treating diseases of living organisms.
[0007]
The second object of the present invention is to provide a magnetic storage medium and magnetized water for information storage used in the above disease prevention / treatment methods.
[0008]
A third object of the present invention is to provide a ceramic body of an information storage medium used for the above disease prevention / treatment method.
[0008]
[Means for Solving the Problems]
In order to achieve the first object, the first disease prevention / treatment method according to the present invention comprises: Has the magnetic force necessary to store material information in a magnetic storage medium A magnetic storage medium storing a pathogen, a foreign substance for a living body, an antigen or the like or information thereof is arranged near the north pole of the linear magnetic field generated between the N and S poles of the magnet. Magnetic storage medium in a curved magnetic field generated outside the magnetic field After placing , A medium of the bending magnetic field or a substance containing the medium Take out non-human It is characterized by being administered in a living organism or a living environment.
[0009]
The second disease prevention / treatment method according to the present invention comprises: Has the magnetic force necessary to store material information in a magnetic storage medium Activated leukocytes and other cells, antibodies, biological defense function enhancers, or magnetic memory storing these information in the vicinity of the north pole of the linear magnetic field generated between the opposing faces of the north and south poles of the magnet While placing an object such as a medium, the magnetic storage medium is placed in the linear magnetic field closer to the S pole than these objects. After placing The medium placed near the S pole of the linear magnetic field or a substance containing the medium Take out non-human It is characterized by being administered in a living organism or a living environment.
[0010]
A third disease prevention / treatment method according to the present invention is characterized by performing the above two methods in combination.
[0011]
the above Disease prevention and treatment The magnetic storage medium for information storage used in the method is an iron oxide film or an iron oxide film coated with cobalt; and a saturated solution in which a permanent magnet mainly composed of neodymium and iron is dissolved in dilute hydrochloric acid. A 1% dilactyl dilactate 1% solution is mixed at a ratio of 10% by volume, dried and crystallized at 120 ° C. or lower, magnetized, then pulverized, infiltrated with an aqueous solution of the powder, and dried. And are preferably bonded together.
[0012]
Also, above Disease prevention and treatment For information storage used in the method Magnetic storage media Is mixed with a solution of a permanent magnet mainly composed of neodymium, iron and boric acid in dilute hydrochloric acid, and an equivalent amount of 1% sodium dilactyl germanate solution is mixed with this solution and dried at 120 ° C. or lower. 1% aqueous solution of powder that has been crystallized, magnetized and then pulverized Magnetic storage medium water for information storage Is preferred.
[0013]
The above information is stored Magnetic storage medium water The medium such as this as it is Non-human It may be used by being administered in a living organism or an environment of a living organism, but it may be used as a ceramic body diluted with water, kneaded into a ceramic material, dried and fired.
[0014]
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings.
Substances such as elements, compounds, life forms, antigens, and antibodies each have a unique wavelength waveform. Therefore, information on these substances is stored in magnetic storage media. To the body The present invention has been made by repeating various experiments under the idea that if it can be stored (transferred) and reproduced, it can be used for various useful purposes.
[0015]
For this invention, first, a magnetic device as shown in FIG. 1 was prepared in order to store information on a substance in a magnetic storage medium using strong magnetism.
This device uses a permanent magnet 1 such as a horseshoe magnet in which the N pole and the S pole are opposed to each other with a predetermined interval. From the N pole to the S pole of the magnet 1, the N pole is changed to the S pole. A linear magnetic field 2 in which the magnetic lines of force are directed straight is generated.
In addition, a curved magnetic field 3 is generated outside the linear magnetic field 2 and the magnetic field lines are curved from the N pole toward the S pole.
[0016]
Various experiments were performed using the apparatus shown in FIG.
First, as Experiment 1, an aquatic product such as shrimp infected with a virus is placed near the north pole of the linear magnetic field 2, and the magnetic storage medium is placed near the south pole. Magnetic storage medium water Put. After about 60 seconds Magnetic storage medium water When (memory water) was taken out and put into the breeding water of virus-infected shrimp, it died earlier than virus-infected shrimp in normal breeding water.
[0017]
On the other hand, in Experiment 2, a blood cell collected from shrimp blood whose biological defense function was enhanced with a biological defense (immunity) enhancer was placed near the north pole of the linear magnetic field 2 and magnetized near the south pole of the linear magnetic field 2. As a storage medium Magnetic storage medium water After about 60 seconds Magnetic storage medium water When (memory water) was taken out and placed in the breeding water of virus-infected shrimp, the survival rate was equivalent to that of normal shrimp in normal breeding water.
[0018]
This means that if an antigen or antibody is placed near the north pole of the linear magnetic field 2 and a magnetic storage medium is placed near the south pole, the unique information possessed by the antigen or antibody is stored in the magnetic storage medium as a positive transfer. Moreover, it is considered that the information stored in the storage medium is reproduced in the breeding tank and acts on the shrimp in the breeding tank.
[0019]
However, as an experiment 3 related to the experiment 1, an aquatic product such as shrimp infected with a virus is placed near the north pole of the linear magnetic field 2 and a curved magnetic field 3 generated outside the linear magnetic field 2 of the magnet 1. Magnetic storage media Body After about 60 seconds, when this medium was put into the breeding water of virus-infected shrimp, as in Experiment 2, the survival rate was the same as that of normal shrimp in normal breeding water.
[0020]
Further, only the storage medium storing the antigen of the living organism and the information of this antigen is placed near the N pole of the linear magnetic field 2, and the magnetic storage medium is stored in the bending magnetic field 3 as described above. Body When this storage medium was placed in the breeding water of virus-infected shrimps, the survival rate was the same as that of normal shrimps, as in Experiment 2.
[0021]
This is because a magnetic storage medium storing an antigen of an organism or antigen information is placed near the north pole of the linear magnetic field 2, and the magnetic storage medium is placed in the curved magnetic field 3 outside the linear magnetic field 2. Body Put it in the curved magnetic field 3 Magnetic storage medium water In a medium such as the above, information against the antigen (hereinafter referred to as reverse information) is stored as reverse transcription, that is, stored as information having an antiviral function and reproduced in a shrimp breeding environment. Conceivable.
[0022]
Next, embodiments of the present invention will be illustrated.
In the first embodiment, as shown in FIG. 2, a pathogen such as a virus, a life form having a pathogen, or a magnetic storage medium (hereinafter referred to as “antigen 4”) in which such information is stored near the north pole of the linear magnetic field 2. And a magnetic storage medium in the bending magnetic field 3 Body 5 For about 60 seconds. By doing so, the information of the antigen 4 is reversely transferred to the medium 5 of the bending magnetic field 3, and the medium 5 becomes a substance having information having a resistance to the antigen 4.
Thus, the disease caused by the pathogen of the organism can be prevented by mixing this substance with the feed of the organism and administering it, adding it to ceramics and putting it into the breeding tank, or using it as breeding water in the breeding tank. Healed.
[0023]
In the above-described embodiment, it is more preferable to use a magnetic storage medium in which information on the antigen is stored as the antigen placed near the north pole of the linear magnetic field 2 than to use the antigen itself. This is because antigens are generally harmful and are safe to use in the form of storage media rather than being handled directly.
As shown in FIG. 3, the magnetic storage medium in which such information is stored has a natural antigen 4a such as a virus or pathogen placed near the north pole of the linear magnetic field 2, and the magnetic storage medium 4b is placed on the south pole side. Can be generated by placing. That is, the information on the raw antigen 4a is transferred to the magnetic storage medium 4b in the linear magnetic field 2 to obtain the magnetic storage medium 4b in which the information on the raw antigen 4a is stored.
[0024]
In the second embodiment of the present invention, as shown in FIG. 4, the biological defense function enhancer or the biological tissue in which the biological defense function is enhanced near the north pole of the linear magnetic field 2 of the magnet 1, or these substances A magnetic storage medium in which an object such as a magnetic storage medium (hereinafter referred to as antibody 6) that stores the information is placed in the linear magnetic field 2 closer to the S pole than the antibody 6 is stored. Body 5 For about 10-60 seconds. After that, the medium 5 is treated in the same manner as described above. Non-human It is administered in a living organism or living environment.
That is, in this embodiment, the information on enhancing the biological defense function is stored in the magnetic field in the linear magnetic field 2. To the body Positive transfer.
[0025]
In this case as well, the antibody 6 itself such as a biological defense function enhancer or a biological tissue with enhanced biological defense function may be directly placed near the north pole of the linear magnetic field 2, but preferably the information of the antibody 6 is forward-transcribed. A magnetic storage medium stored in (1) may be placed. This magnetic storage medium is obtained by placing the antibody 6 near the north pole of the linear magnetic field 2 of the magnetic device and placing the magnetic storage medium near the south pole in the same manner as in FIG. The magnetic storage medium stores information on the antibody 6.
[0026]
The magnet apparatus shown in FIGS. 1 to 4 shows a preferable example used in the method of the present invention, and the present invention is not limited to this. For example, as shown in FIG. 5, a pair of left and right magnets 1a and 1b are arranged so that their north and south poles face each other at a predetermined interval, and a straight line is formed between the opposing faces of the opposite north and south poles. It is also possible to use a magnet device in which a magnetic field 2 is generated and a curved magnetic field 3 along the linear magnetic field 2 is generated outside the linear magnetic field 2.
[0027]
5 further generates a curved magnetic field 7 from the north pole of each magnet 1a, 1b to the south pole, and a curved magnetic field 3 from the north pole of the magnet 1a to the south pole of the magnet 1b. However, the region where the medium 5 for reverse transfer is placed is the curved magnetic field 3 from the N pole of the magnet 1a toward the S pole of the magnet 1b.
In the apparatus of FIG. 5, the linear magnetic field 2, the curved magnetic field 3, and the outer curved magnetic field 8 are partitioned by a frame 9.
[0028]
When the apparatus of FIG. 5 is used, when taking out the stored medium of the linear magnetic field 2, it is necessary to remove the magnets 1 a and 1 b so as not to be affected by the outer curved magnetic field 8. For the same reason, in order to take out the medium of the bending magnetic field 3 to which the information of the antigen 4 is reversely transferred, it is necessary to remove the magnets 1a and 1b or to take out from the direction opposite to the direction of the magnetic field of the bending magnetic field 3.
[0029]
The magnetic storage medium for information storage used in the method of the present invention is an iron oxide film or an iron oxide film coated with cobalt; a permanent magnet mainly composed of neodymium and iron is dissolved in diluted hydrochloric acid, and a saturated solution thereof On the other hand, 1% solution of dilactyl digermanate 2% sodium lactate is mixed in a ratio of 10% by volume, dried and crystallized at 120 ° C. or less, magnetized, and pulverized. A sheet obtained by laminating a sheet which has been infiltrated or coated and dried is preferable.
[0030]
For the information storage used in the method of the present invention Magnetic storage medium water Is mixed with a solution of a permanent magnet mainly composed of neodymium, iron and boric acid in dilute hydrochloric acid, and an equivalent amount of 1% sodium dilactyl germanate solution is mixed with this solution and dried at 120 ° C. or lower. A 1% aqueous solution of powder that has been crystallized and magnetized and then ground is preferred.
[0031]
The medium 5 in which the antigen 4 is stored by reverse transcription and / or the medium 5 in which the antibody 6 is stored by forward transcription is used as it is. Non-human Although it may be administered in a living organism or a living environment, a ceramic body kneaded in a ceramic material, dried and fired may be administered in a living environment via water.
The ceramic body in this case has the following forms.
[0032]
In the first form, a magnetic storage medium in which information such as antigen 4 or information such as antigen is stored is arranged near the north pole of the linear magnetic field 2 generated between the N pole and S pole facing surfaces of the magnet 1. For storing information as the medium 5 in the bending magnetic field 3 generated outside the linear magnetic field 2 Magnetic storage medium water Put this Magnetic storage medium water Is a ceramic body obtained by mixing and drying the ceramic material.
This ceramic body is a ceramic body that stores the reverse information of the antigen 4.
[0033]
In the second mode, an object such as a magnetic storage medium storing information such as antibody 6 or the antibody is placed near the linear magnetic field 2N pole generated between the N pole and S pole facing surfaces of the magnet 1. For storing information as the medium 5 in the linear magnetic field 2 closer to the S pole than these objects Magnetic storage medium water Put this Magnetic storage medium water Is a ceramic body obtained by mixing and drying the ceramic material.
This ceramic body is a ceramic body that stores positive information of the antibody 6.
[0034]
In the third embodiment, the magnetic storage medium storing the antigen 4 or the antigen information is arranged near the north pole of the linear magnetic field 2 generated between the facing surfaces of the north and south poles of the magnet 1. For information storage as a medium 5 in a bending magnetic field 3 generated outside the linear magnetic field 2 Magnetic storage medium water Put this Magnetic storage medium water The ceramic is obtained by placing it near the south pole of the linear magnetic field 2 on which an object such as the magnetic storage medium storing the antibody 6 or antibody information is placed, and then mixing and drying and firing the ceramic material. Is the body.
This ceramic body is a ceramic body that stores the reverse information of the antigen 4 and the positive information of the antibody 6.
[0035]
Examples of the present invention will be given below.
In addition, all of the experimental examples (Examples 1 to 6) listed here were conducted by Prof. Yukinori Takahashi of the National Fisheries University Department of Bioproduction, Department of Epidemiology, as a commissioned test study.
[0036]
(Example 1) Activity control action of baculovirus by baculovirus reverse information-1
Test method
For about 10 days, baculovirus was forcibly infected from about 300 healthy prawns with an average weight of about 12.5 g, which were preliminarily raised for about 10 days. From this treated and untreated shrimp, selection was made to remove shrimp with abnormal activity due to stress, etc., and the following five test zones of 30 fish were organized and accommodated in each 200 liter water tank.
The three groups of the present invention test area use memory water obtained by reverse transcription of the information wave of baculovirus with a curved magnetic field 4.
The first test group is a group using baculovirus reverse transcription memory water (reversed water) for breeding water in the breeding tank
The second test group was a group administered with mixed feed pellets sprayed with baculovirus reverse transcription memory water (reverse water)
The third test group is a group using breeding water treated with ceramics made with reverse transcription memory water
The fourth test group is a control group forcibly infected with baculovirus.
The 5th test zone is an untreated healthy shrimp control group
It is.
[0037]
The forced infection method consists of peeling the crust of the cranio-thoracic region of three crawfish prawns that weighed about 10 g, and homogenized in 40 ml of sterile seawater, followed by centrifugation (10,000 × g, 10 min, 4 min. The environmental infectious solution was adjusted at a ratio of 1 ml of the supernatant obtained at ℃) to 2,000 ml of seawater. The shrimp during the pre-breeding were immersed in this for 2 hours to force infection. The reverse transfer storage water was prepared by placing the supernatant near the north pole of the linear magnetic field 2 of the apparatus and placing the storage water in the curved linear magnetic field 3 of the magnet 1.
After group formation in each ward, the animals were reared for 10 days while maintaining the baculovirus activation temperature at a rearing water temperature of 22 ° C., and the feeding and moribund conditions were observed. The moribund shrimp was confirmed to be moribund by baculovirus by PCR and pathological examination.
[0038]
Test results: Table 1 shows the cumulative number of dead prawns, the cumulative drowning rate, and the daily remaining food rate of each morning prawn after forced infection with baculovirus in the test group and the control group of the present invention.
[Table 1]

[0039]
As is clear from Table 1, the shrimp in the control group (4th test group) of the infection-treated group after catastrophic infection with baculovirus showed devastating death within 10 days, whereas the mortality rate in the test group of the present invention Was 30-40%, with a significant difference between them (p <0.05). Moreover, the mortality rate of the untreated control group (healthy shrimp) was about 27%, and no significant difference was observed with the test group (p <0.05). That is, the forced infection group also controlled the acute viremia caused by the baculovirus by the three treatments of the present invention, and showed almost the same survival as the healthy shrimp.
In addition, about 27% of untreated control plots (healthy shrimp) were drowned due to the stress caused by the transfer from the reserve tank to the test tank and the stress of the narrow test tank.
From this test, baculovirus that invaded the prawns received information that seems to be the reverse information of baculovirus activity from the environment breeding water or the information that seems to be the reverse information of baculovirus activity orally. It turned out that it fell. Moreover, the fact that baculovirus activity is controlled only by information without using conventional drugs has been revealed.
[0040]
(Example 2) Activity control action of baculovirus by baculovirus reverse information-2
Test method: Using shrimp having an average body weight of 11.5 g, the same treatment as in Example 1 was performed to set the following five test sections.
The first test group is a group using baculovirus reverse transcription memory water (reversed water) for breeding water in the breeding tank
The second test group was a group in which breeding water treated with ceramic prepared with reverse transcription memory water was used, and baculovirus reverse transcription memory water (reversal water) was sprayed with a mixed feed beret.
The third test group is a group in which a magnetic storage medium in which a baculovirus is stored is arranged in the linear magnetic field 2 and the water of the curved magnetic field 3 is constantly circulated through a breeding tank through a pipe.
The fourth test group is a control group forcibly infected with baculovirus.
The fifth test zone is an untreated healthy shrimp control group.
[0041]
Test results: Table 2 shows the cumulative number of dead prawns, the cumulative drowning rate of the prawns after the baculovirus forced infection in the test group of the present invention and the control group, and the remaining food rate in the morning of each day.
[Table 2]

[0042]
As is apparent from Table 2, after the baculovirus forced infection, the infection control treatment group died 100% in 9 days, whereas the test group 3 according to the present invention was about 35%, There was a significant difference (p <0.01). From the results of the test group 3, it was found that the activity of baculovirus can be controlled by constantly reversing the breeding environment water without using magnetized memory water. This treatment speed is 1 rotation / 12 hours or more of breeding water. In addition, there was no significant difference in the mortality rate between the uninfected untreated control group and the test group of the present invention.
[0043]
(Example 3) Control action of baculovirus activity by biological defense function improvement information
Test method: Using shrimp having an average weight of about 12.0 g, the same treatment as in Example 1 was performed, and the following five test sections were set up.
The two wards of the control ward are untreated healthy groups with the forced infection treatment group as described above.
Three test groups of the present invention are groups using not the reverse information of baculovirus but the normal information of the antibody that improves the biological defense function. Ten or more fish are raised separately in advance, and peptidoglycan (PG) is administered in an appropriate amount for an appropriate period. It has already been confirmed that this treatment enhances the shrimp's defense function. In this test, blood was collected from several of these shrimps and transferred from the centrifugally treated solution to storage water and magnetic storage medium using a magnetic device.
The first test group was a group in which the feed pellets sprayed with this memory water were administered to prawns
The second test group is a group that treated the breeding environment water by immersing the ceramic created using the stored water in the aquarium.
Third test Ward A magnetic storage medium in which blood information is stored is reversely retransferred to create a new magnetic storage medium, which is placed on the linear magnetic field N pole side of the magnetic device, and the water of the curved magnetic field 4 is piped to the breeding aquarium A group that always circulates through. The breeding environment water that has passed through this pipe is changed to blood information (positive) → reverse (negative) → re-reverse (positive) for enhancing the biological defense function.
The fourth test group is a control group forcibly infected with baculovirus.
The fifth test zone is an untreated healthy shrimp control group.
[0044]
Test results: Table 3 shows the cumulative number of dead prawn tails, the cumulative drowning rate of the prawns after the baculovirus forced infection in the test group of the present invention and the control group, and the remaining food rate in the morning of each day.
[Table 3]

[0045]
As shown in Table 3, in the untreated control group, the death rate after 10 days was only 36.7%, whereas in the forced infection control group, 96.7% died. On the other hand, test group 1 in which biological defense information storage water was sprayed on food, test group 2 in which breeding water was treated with ceramic made using the storage water, and breeding water was circulated constantly using the device. The mortality rate in test group 3 was 40.0%, 33.3%, and 33.3%, respectively. Intention Difference was observed (p <0.05).
At the same time, the death rate was almost the same as the untreated control.
[0046]
(Example 4) Baculovirus activity control action by combined use of baculovirus reverse information and biological defense function positive information-part 1
Test method: Using shrimp having an average body weight of about 12.5 g, exactly the same treatment as in Example 1 was performed to set five test sections.
The test group of the present invention is divided into four sections, the first test section to the fourth test section, all of which have a storage medium that reversely transcribes baculovirus information and a memory that stores the information from blood with enhanced biological defense functions. It is a ward that uses a medium together. The control group is only the compulsory infection treatment group.
The first test group is a group that sprays and feeds pellets with stored water in which both baculovirus reverse information and biological defense information are stored.
The second test zone is a group that treats the breeding environment water using ceramics made from the same two types of memory as the first test zone.
3rd test zone Is the first This is a combination of 1 test zone and 2nd test zone.
The fourth test zone is a group in which the breeding environment water is constantly circulated through a magnetic device in which two kinds of information storage media are installed, and baculovirus reverse information and biological defense information are administered to the breeding environment water.
The fifth test group is a control group forcibly infected with baculovirus.
[0047]
Test results: Table 4 shows the number of cumulative moribund tails, cumulative mortality and residual food rate (each morning) after baculovirus infection in the test group of the present invention and the control group.
[Table 4]

[0048]
As shown in Table 4, after baculovirus forced infection, more than 90% of the control group died after 10 days. On the other hand, the bait and ceramic groups, which were given two information on virality and biological defense, had a mortality rate of approximately 30%, and the bait and ceramic combination group had a mortality rate of 20% or less. Furthermore, the ward death rate of 15% or less was obtained in the section where the breeding environment water was processed using the magnetic device for the two pieces of information. All test groups showed a significant difference in mortality compared to the control group (p <0.05).
[0049]
(Example 5) Baculovirus activity control action by combined use of reverse information of baculovirus and positive information enhancing biological defense function-Part 2
Test method: Using shrimp having an average body weight of about 14.0 g, the same treatment as in Example 1 was performed to set five test sections. The first test group to the fourth test group are test groups according to the present invention 2, and the control group is only the forced infection treatment group.
In the first test group, the ceramic prepared by combining the reverse information of baculovirus and the positive information on the enhancement of biological defense function is used for breeding environment water, and at the same time, the pellet is treated with both information storage waters and administered (Example 4). (Same as Test Zone 3)
The second test section is a section in which a magnetic storage medium and pipes storing baculovirus reverse information and biological defense function enhancement positive information are installed in a magnetic device, and outside air is constantly sent to aerate the breeding environment water.
The third test zone is a modification of the second test zone, in which a water box is placed in the middle of the air supply pipe and the air after the water in the box is aerated is sent to the breeding environment water and re-aerated. This water box is for information storage. Magnetic storage medium water It was used.
The 4th test zone is a combination of the 1st test zone and the 3rd test zone, that is, for food treatment, breeding environment water treatment with ceramics and information storage. Magnetic storage medium water It is a ward where the breeding environment water treatment is performed by aeration.
[0050]
Test results: Table 5 shows the number of cumulative moribund tails, cumulative mortality and residual food rate (each morning) after baculovirus infection in the test group of the present invention and the control group.
[Table 5]

[0051]
As shown in Table 5, after baculovirus forced infection, 90% or more of the infected control group died within 10 days, whereas 20% in the first test group that used both the bait treatment and the ceramic environmental water treatment. The drowning rate. The mortality rate was 25% or less in the second test area where the breeding environment water was treated by aeration. Furthermore, the mortality rate was 10% in the third test section in which artificial biological water was installed in the middle of the air supply pipe. In addition, the mortality rate was 15% or less in the four test sections combined with aeration using bait, ceramic, and magnetized water for information storage. All of the test groups of the present invention showed a significant difference in the mortality rate compared with the control group (p <0.05).
[0052]
(Example 6) Activity control action of baculovirus by information on biological defense function enhancer
Test method: Using shrimp having an average body weight of about 13.0 g, the same treatment as in Example 1 was performed to set the following five test sections. There are two control zones: the forced infection treatment group and the untreated healthy group. The first test group to the third test group are the test groups of the present invention, and all of them use the information obtained by directly storing the information on the biological defense function enhancer peptidoglycan by the positive transcription. In addition, the control group has two groups, a forced infection treatment group and an untreated healthy group.
In the first test section, a peptidoglycan information transfer solution is prepared using a magnetic device, a magnetic storage medium, and magnetic storage water, and the pellet is processed and administered therewith.
In the second test section, ceramics were prepared using peptidoglycan information storage solution, and it was used to treat the breeding environment water.
The third test section is a section in which a pipe is installed in a magnetic device in which a magnetic storage medium in which peptidoglycan information has been stored is arranged, and the outside air is ventilated to the breeding environment water after passing the artificial water.
The fourth test group is a control group forcibly infected with baculovirus.
The fifth test zone is an untreated healthy shrimp control group.
[0053]
Test results: Table 6 shows the number of cumulative moribund tails, cumulative mortality and remaining food rate (each morning) after baculovirus infection in the test group of the present invention and the control group.
[Table 6]

[0054]
As shown in Table 6, the baculovirus-infected control group was annihilated after 9 days. In the untreated healthy area, 30% drowned and there was a significant difference between them. All the test plots had a mortality rate of about 50%, showing a significant difference from the infected control plot, but no significant difference from the untreated healthy plot.
[0055]
In the above description, an example in which the present invention is applied mainly to baculovirus infection in shrimp culture has been shown, but the present invention is not limited thereto, and yellowtail iridovirus infection, streptococcal disease, flounder Herpesvirus infection, ayu pseudomonas disease and cold water disease, abalone viral muscle atrophy, porcine mycoplasmosis (SEP), Aujeszky's disease, genital organs, respiratory syndrome, chicken colibacillosis, mycoplasmosis (CDR) It can be widely applied to prevention and treatment of various diseases of various organisms.
[0056]
【effect】
Since the present invention uses the reverse information wave of antigen to suppress the activity of a pathogen (antigen) such as a virus and the positive information wave of an antibody that enhances the immune function of a living organism to prevent and treat a disease. It is possible to grow a living organism without using any direct administration of chemical agents. Therefore, public health problems due to the use of chemical agents are eliminated.
[0057]
In addition, as is clear from the experimental examples, a group of organisms that are forcibly infected with a virus and die 100% in a few days if left untreated are equivalent to a group of organisms that are not infected according to the method of the present invention. Because of its survival rate, its disease prevention and treatment effects are tremendous, and it has never been seen before.
Therefore, a significant economic effect is brought about in the cultivation of living organisms, particularly fish and shellfish.
[0058]
When using a magnetic storage medium that stores information waves of antigens and antibodies, it is safe because there is no need to handle harmful antigens directly, and it is efficient because the stored magnetic storage medium can be used repeatedly. Good.
[Brief description of the drawings]
FIG. 1 is a schematic configuration diagram of a magnetic device used in the method of the present invention.
FIG. 2 is a schematic diagram showing an embodiment of the method of the present invention.
FIG. 3 is an explanatory diagram of a production process of a magnetic storage medium storing antigen information.
FIG. 4 is a schematic diagram showing another embodiment of the method of the present invention.
FIG. 5 is a schematic configuration diagram of another magnetic device used in the method of the present invention.
[Explanation of symbols]
1, 1a, 1b ... Magnet
2 ... Linear magnetic field
3 ... Bending magnetic field
4, 4a ... antigen
4b: Magnetic storage medium storing antigen information
5 ... Medium
6 ... Antibodies
7… Curve magnetic field
8 ... Outer curve magnetic field
9 ... Frame

Claims (9)

Close to the north pole of the linear magnetic field generated between the opposing faces of the north and south poles of the magnet having the magnetic force necessary to store the substance information in the magnetic storage medium, A magnetic storage medium storing these pieces of information is arranged , and after placing the magnetic storage medium in a curved magnetic field generated outside the linear magnetic field, the curved magnetic field medium or a substance containing the medium is taken out and a person is removed. Disease prevention / treatment methods for organisms other than the human body, characterized by being administered in an organism other than the above or in an animal breeding environment Activated leukocytes and other cells and antibodies near the north pole of the linear magnetic field generated between the opposing faces of the north and south poles of the magnet having the magnetic force necessary to store the substance information in the magnetic storage medium An object such as a biological defense function enhancer or a magnetic storage medium storing these pieces of information is placed, and after placing the magnetic storage medium in the linear magnetic field closer to the S pole than these objects, the S pole of the linear magnetic field A method for preventing or treating a disease of a living organism other than a human body, characterized in that the medium placed close to the medium or a substance containing the medium is taken out and administered to a living organism other than a human or a living environment of the living organism. A material containing the medium or the medium was placed in the curved magnetic field of claim 1, wherein the material comprising the medium or the medium were placed in S-pole side of the said linear magnetic field according to claim 2, the non-human organism Or a disease prevention / treatment method for living organisms other than the human body, characterized by being administered simultaneously in the living environment of the living organism The magnetic storage medium placed near the north pole of the linear magnetic field is an iron oxide film or an iron oxide film coated with cobalt; a permanent magnet mainly composed of neodymium and iron is dissolved in dilute hydrochloric acid, and the saturated solution Then, 1% solution of dilactyl germanate 2% sodium lactate is mixed at a ratio of 10% by volume, dried and crystallized at 120 ° C. or lower, magnetized and then pulverized, and the aqueous solution of the powder is infiltrated or And a magnetic storage medium placed near the curved magnetic field or the linear magnetic field S pole, in which a permanent magnet mainly composed of neodymium, iron, or boric acid is dissolved in dilute hydrochloric acid. 1% aqueous solution of dilactylgermanate dilactylate and 1% sodium lactate solution mixed with this, dried and crystallized at 120 ° C. or less to magnetize the crystal, and then pulverized powder Biological method of disease prevention and treatment, except the human body according to claim 1, 2, 3, wherein a is Iron oxide film or iron oxide film coated with cobalt; 10% by volume of 1% solution of dilactyl dilactate 2% sodium lactate in a saturated solution in which a permanent magnet mainly composed of neodymium and iron is dissolved in dilute hydrochloric acid It is mixed at a ratio, dried and crystallized at 120 ° C. or less, magnetized, then pulverized, infiltrated with an aqueous solution of the powder, and a dried sheet; Magnetic storage media for information storage of life forms A permanent magnet mainly composed of neodymium, iron, and boric acid is dissolved in dilute hydrochloric acid and mixed with an equal amount of 1% dilactyl germanate dilactate solution. The mixture is dried and crystallized at 120 ° C or lower. Magnetic storage medium water for information storage of living organisms, characterized in that it is a 1% aqueous solution of powder that has been magnetized and then pulverized Close to the north pole of the linear magnetic field generated between the opposing faces of the north and south poles of the magnet having the magnetic force necessary to store the substance information in the magnetic storage medium, The magnetic storage medium storing these pieces of information is arranged, and the magnetic storage medium water for information storage is placed in the curved magnetic field generated outside the linear magnetic field, and the magnetic storage medium water is mixed with the ceramic material. Information-stored ceramic body dried and fired Activated leukocytes and other cells, antibodies, near the linear magnetic field N pole generated between the opposing faces of the N pole and S pole of the magnet having the magnetic force necessary to store the substance information in the magnetic storage medium , with placing an object such as a magnetic storage medium storing biological defense function enhancers or their information, placing the linear magnetic field in the information storing magnetic storage medium water S poles nearer these objects, the magnetic storage medium water Information-stored ceramic body made by mixing and drying and firing ceramic materials Close to the north pole of the linear magnetic field generated between the opposing faces of the north and south poles of the magnet having the magnetic force necessary to store the substance information in the magnetic storage medium, An object such as a magnetic storage medium in which a magnetic storage medium storing these pieces of information is disposed, and an information storage magnetic storage medium water placed in a curved magnetic field outside the linear magnetic field is stored in an antibody or antibody information. An information-stored ceramic body that is placed near the S pole of a linear magnetic field and then mixed with a ceramic material and dried and fired

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