JP3824890B2 - Dry bulk food / pharmaceutical dry bulk crusher - Google Patents

Description

[0001]
[Technical field to which the invention belongs]
The present invention is a freeze-drying method for pulverizing a dry bulk of a liquid material that has been dried in a drying means that adjusts food, medicine, etc. to a liquid and freeze-drys it in a drying cabinet (drying chamber) of a freeze-dryer. The present invention relates to improvement of a dry bulk crusher for foods and pharmaceuticals.
[0002]
[Prior art]
Raw materials such as food and medicine, to adjust to liquid materials, and dry bulk of the grinding of liquid material that was finished and dried by freeze-drying that by the freeze-drying machine, in the previous, usually, the adjusted liquid material A container such as a tray is filled, and the whole container is charged into a drying cabinet (drying chamber) of a freeze dryer and frozen in the container, and sublimation heat is supplied under vacuum to supply moisture in the material. Sublimate and collect the water vapor in a cold trap of the evacuation system that passes to the drying chamber, freeze-dry it, and then dry the dried liquid material together with the container from the drying chamber, The dried product is discharged to the outside as a dry bulk, and this dry bulk is put into a pulverizer and pulverized.
[0003]
[Problems to be solved by the invention]
The above-mentioned means for pulverizing the dry bulk of food / pharmaceutical liquid materials freeze-dried by a freeze-dryer is necessary to ensure that the resulting powdered product is aseptic and to prevent contamination bazaars. Even if the liquid material is charged into the storage room in a state where it is shut off from the outside, the process of unloading the dried product from the freeze-dryer drying chamber together with the container, and the dried product from the unloaded container in bulk form Each process of taking out the dried bulk and feeding the taken-out dry bulk into the inlet of the pulverizer must be performed in a state of being blocked from the outside, which poses a troublesome problem.
[0004]
Moreover, in reality, it is almost impossible to pulverize the dried bulk of the liquid material that has been dried in the dryer of the freeze dryer because of the structure of the freeze dryer. is there.
[0005]
The present invention has been made to solve the above-mentioned problems occurring in the conventional means, so that the dry bulk of the lyophilized liquid material can be pulverized substantially in the body of the lyophilizer. It aims to provide a new means to do.
[0006]
[Means for Solving the Problems]
The means of the present invention for achieving the above-mentioned object has been completed on the basis of knowledge obtained through various studies on the structure of the freeze dryer and the shape and properties of the dried bulk of the liquid material that has been dried. is there.
[0007]
In other words, the freeze dryer forms its drying chamber into an upright cylindrical tube so that the liquid material is frozen into a hollow cylindrical shape on the inner wall surface of the tube, and the moisture in the material is kept under vacuum. If the water vapor is collected by a cold trap of an evacuation system connected to the upper end side of the tube and freeze-dried, a dried product of the cylindrical liquid material that has been dried in the tube is obtained. The tube can easily fall downward from the inside of the tube due to its own weight, and a cylindrically formed collection chamber is formed below the tube so that its axial center line is aligned with that of the tube. Coordinated and airtightly connected to the lower end of the tube, so that when the dried liquid material (dry bulk) that has been dried in the tube is dropped from the tube, the liquid The dried product can be received and collected in this cylindrical collection chamber, and the dried product of the liquid material that has finished drying in the tube and dropped from the tube is extremely fragile. This is because it was easily crushed by applying impulsiveness, and the knowledge that it was possible to pulverize it into powder by blowing pressurized air from a nozzle was obtained. .
[0008]
And from this, in the cylindrical recovery chamber connected to the lower end side of the upright cylindrical tube as the freeze dryer dryer, provided with a discharge port for discharging the pressure inside it to the outside, Drying of the liquid material that has been freeze-dried in an upright cylindrical tube by installing a fusible nozzle on the inner surface side of the peripheral wall of the recovery chamber, which blows out compressed air toward the inside of the recovery chamber When the product is dropped into the collection chamber and blown with blown air from the fusible nozzle provided on the inner wall of the collection chamber, the dried product of the liquid material dropped into the collection chamber is crushed and crushed into powder. This is because the dried product thus obtained can be taken out from the outlet together with the exhaust of the compressed air.
[0009]
Therefore, in the means of the present invention, as means for achieving the above-described object, the drying chamber for charging the liquid material to be dried described in claim 1 and the circulation of the heat medium attached to the drying chamber are provided. It consists of a jacket for the ring and an evacuation system equipped with a vacuum pump and a cold trap connected to the drying chamber. The liquid material charged in the drying chamber is frozen, and moisture in the material is removed from the liquid material. The drying cabinet of the freeze dryer that is sublimated and dried is formed into an upright cylindrical tube that freezes the liquid material on the inner wall surface, and a duct that leads to the vacuum exhaust system is connected to the upper end of the tube, and the outer circumference of the tube to So設a jacket for circulating a heat medium, the lower end of the tube, the collection chamber pointing accept dry bulk of the liquid material has finished dried within the tube, the inner diameter of the tube and Hobodo diameter to large Diameter Exhaust that is formed in a cylindrical shape with a diameter, and is arranged and connected so that its axial center line is substantially aligned with the axial center line of the tube, and communicates with the appropriate part of the peripheral wall of this cylindrical recovery chamber A liquid material that is provided in the inner wall of the peripheral wall with a jet nozzle that ejects a jet of air toward the recovery chamber and falls into the recovery chamber from the tube by the air jet that is ejected from the jet nozzle. The present invention proposes a dry bulk grinding apparatus for freeze-dried foods and chemicals, characterized in that the dry bulk of this product is crushed and discharged from an exhaust port.
[0010]
Further, in addition thereto, the duct leading to the vacuum exhaust system connected to the upper end of the upright cylindrical tube to form a drying oven lyophilizer according to claim 2, collecting chamber through the lumen of said tube A blower nozzle that discharges the pressure air toward the nozzle is installed, and the dry bulk pulverization by the jet of air from the jet nozzle provided in the recovery chamber is discharged from the discharge nozzle and the inside of the recovery chamber through the lumen of the tube. The pulverization apparatus for dry bulk of freeze-dried food / drugs according to claim 1, wherein the apparatus is carried out in a flow of pressure air discharged from an exhaust port.
[0011]
Moreover, the collection chamber of the main body portion provided by connecting the lower end of the upright cylindrical tube to form a drying oven lyophilizer according to claim 3, formed into a substantially corresponding tubular to said tube, and In the bottom part of the tube, an enlarged diameter part larger than the inner diameter of the tube is formed, and the exhaust port is opened to a part that deviates laterally from a position directly below the tube at a position close to the periphery of the bottom plate of the enlarged diameter part. A dry bulk crusher for freeze-dried food / drugs according to claim 1 or claim 2 and a lower end of an upright cylindrical tube forming a dryer of the freeze-dryer according to claim 4 Cyclone intake or cyclone intake with a cyclone in which an exhaust port is provided at the bottom of a cylindrical collection chamber connected to the side, and the exhaust port is separated into powder and air by a centrifugal method Characterized by connecting Claim 1 or claim 2 lyophilized dry bulk pulverizer food and chemicals according, and the pressure air and pulverized material provided on the bottom of the collection chamber to form a drying oven lyophilizer according to claim 5 The freeze-dried product according to claim 1 or 2, wherein an exhaust port for discharging is connected to an intake port of a cyclone or a pulverizer with a cyclone that is separated into powder and air by a centrifugal method. It proposes a dry bulk crusher for food and medicines.
[0012]
DETAILED DESCRIPTION OF THE INVENTION
The dry bulk crushing apparatus for freeze-dried foods and chemicals according to the means of the present invention is a freeze dryer for drying a liquid material into a dry bulk. The liquid material is frozen in a cylindrical shape on the inner wall surface of an upright cylindrical tube. Then, a freeze-dryer in the form of being freeze-dried by supplying sublimation heat under vacuum is used and combined with an upright cylindrical tube serving as a drying warehouse for the freeze-dryer.
[0013]
Therefore, as shown in FIG. 1, an upright cylindrical tube 1, a jacket 2 for circulating a heat medium surrounding the outer periphery thereof, and a vacuum exhaust system in which the lumen of the tube 1 is equipped with a vacuum pump / cold trap. The main part “a” of the freeze-drying apparatus for freeze-drying the liquid material inserted into the lumen of the cylindrical tube 1 is constituted by the duct 3 connected to the upper end side of the tube 1 so as to be communicated with each other via the valve 30. This is mounted on a machine frame F installed at a desired location.
[0014]
Then, as shown in the chain line in the embodiment shown in FIG. 2, the liquid material is injected into the inlet b for injecting the liquid material into the lumen of the upright cylindrical tube 1 serving as the drying container. The pipe 5 to be led is connected to the lower end side of the tube 1 above the valve V2 provided on the lower end side of the tube 1, and the injection port b is provided at the connection port, or is shown by a solid line in FIG. As shown in the embodiment, the injection port b is formed in the dispensing nozzle 50 and disposed in the duct 3 connected to the upper end side of the tube 1, and the liquid material is supplied to the dispensing nozzle 50. The downstream side of the pipe 5 to be led is connected.
[0015]
In addition, the liquid material fed into the tube 1 is frozen in a cylindrical shape with a hollow center on the inner wall surface 1a of the tube 1, so that the excess liquid material is discharged out of the tube 1 without being frozen. The tube 6 is provided at the bottom of the tube 1 so as to be connected to a portion located above the above-described valve V2 provided therein, so that the liquid material fed into the tube 1 can be supplied to the inside of the tube 1. The wall surface 1a is frozen in a cylindrical shape, the moisture in the material is sublimated from the frozen liquid material, collected and removed by a vacuum exhaust system, and freeze-dried apparatus W for freeze-drying is configured.
[0016]
And, when the dried product (dry bulk) of the liquid material that has been dried in the tube 1 is dropped from the tube 1 to the lower end side of the upright cylindrical tube 1 serving as a drying warehouse thereof, A collection chamber 4 for receiving and collecting it is connected in an airtight manner.
[0017]
When the recovery chamber 4 is connected, if the valve V2 is provided at the bottom of the recovery chamber 4, the valve V1 provided on the lower end side of the tube 1 shown by the chain line in FIG. 2 may be omitted. In this case, the drain pipe 6 for discharging the unfrozen liquid material is provided at a position immediately above the valve V2 at the bottom of the recovery chamber 4, as shown by the solid line in FIG. .
[0018]
The recovery chamber 4 is a cylinder having a capacity and length that can be received as it is even when the liquid material that has been dried in the tube 1 falls in a cylindrical shape that follows the shape of the lumen of the tube 1. It is formed in a shape and connected to the lower end side of the tube 1, and an exhaust port 4 a opened to the outside is opened in this, and the dry bulk of the liquid material falling into the recovery chamber 4 is crushed Jet nozzles n are provided on the inner surface side.
[0019]
In the embodiment shown in FIG. 1, the exhaust port 4a is provided at the bottom of the collection chamber 4, but as in the embodiment shown in FIG. You may provide in an appropriate place.
[0020]
In addition, in the embodiment shown in FIGS. 1 and 2, the jet nozzle n installed on the inner surface side of the recovery chamber 4 in order to pulverize the dry bulk of the liquid material recovered in the recovery chamber 4 is also a recovery chamber. Although it is provided in the body portion of the body 4, it may be installed in an appropriate place, for example, in the case where it is installed in a portion close to the bottom of the peripheral wall of the collection chamber 4 as in the embodiment shown in FIG.
[0021]
At this time, in the case where the exhaust port 4a is provided at the bottom of the recovery chamber 4, the bottom of the recovery chamber 4 is set to the inner diameter of the tube 1 and the main portion 40 of the recovery chamber 4 as in the embodiment shown in FIG. The bottom wall 42 of the recovery chamber 4 that is the bottom surface of the expanded diameter portion 41 is located immediately below the inner wall surface 1a of the tube 1 and the inner surface of the main body 40. Even if the dry bulk of the liquid material that has been dried from the inside of the tube 1 falls in a frozen state, the exhaust port 4a is clogged or clogged. It is effective to prevent it from occurring.
[0022]
In the case where the valve V1 for maintaining the airtightness in the main part a is provided at the bottom of the collection chamber 4 connected to the lower end side of the tube 1, as in the embodiment of FIGS. The connection pipe 43 is connected to an exhaust port 4a provided at the bottom of the recovery chamber 4, and valves V1 and V2 are provided above and below the connection pipe 43, respectively, and the recovery chamber 4 and the tube 1 are hermetically sealed by the upper valve V1. The lower valve V2 may be an open / close valve for discharging the unfrozen liquid material and the pulverized material described later.
[0023]
Further, when the exhaust port 4a is opened at the upper and lower intermediate portions of the circumferential wall of the recovery chamber 4 as in the embodiment shown in FIG. 3, the jet nozzles n are disposed below the exhaust port 4a. The crushing and crushing by the jet from the jet nozzle n that is arranged on the bottom side of the collection chamber 4 and is exposed to the dry bulk of the liquid material that tends to accumulate on the bottom of the collection chamber 4 is performed efficiently. To be
[0024]
The dry bulk of the liquid material pulverized by the jet blown from the jet nozzle n is discharged from the exhaust port 4a opened in the recovery chamber 4 together with the jet from the jet nozzle n and taken out. Therefore, as in the embodiment shown in FIG. 2 or FIG. 4, the transport cylinder 70 is connected to the exhaust port 4a via the valve V2, and the centrifugal cyclone 71 is connected to the tip end thereof. By connecting the inlet 72a of the pulverizer 72 combined with the cyclone 71 as in the embodiment of FIG. 1 or FIG. 3, the powder is taken out from the outlet of the cyclone 71 as a dry powder product.
[0025]
At this time, the powder 1 produced by pulverizing the dry bulk of the liquid material in the recovery chamber 4 rises by the jet of air ejected from the jet nozzle n, and is connected to the upper end side of the recovery chamber 4. May flow into the lumen and the duct 3.
[0026]
For this reason, an air discharge nozzle m that discharges pressurized air under the control of the valve V4 as shown by a chain line in FIG. It is effective to keep the air pressure higher than that in the collection chamber 4.
[0027]
As the discharge nozzle m provided in this way, as shown in the embodiment shown in FIG. 3, the dispensing nozzle 50 provided for dispensing the liquid material to the inner wall surface 1a of the tube 1 is compressed by the switching valve V5. Alternatively, the dispensing nozzle 50 may be used in common by connecting to a pressure source such as a cylinder filled with air.
[0028]
Further, when a liquid material is dispensed on the inner wall surface 1a of the tube 1 and frozen, distilled water is sprayed onto the inner wall surface 1a of the tube 1 to form a thin ice layer. In addition, when the liquid material is frozen on the ice film, when the frozen liquid material is dried, it can be easily detached from the inner wall surface 1a of the tube 1. In this case, a nozzle provided for freezing this distilled water may be connected to a pressure source via a switching valve similar to that described above, and this nozzle may be used in common to discharge compressed air.
[0029]
1 to 4, t1 is a tank for collecting the unfrozen liquid material taken out by the drain pipe 6, P2 is a pump for pumping the collected liquid material into the tank t1, and t2 is pumped by the pumping pump P2. A second tank for storing the liquid material, V5 is a switching valve provided in the pipe 5 so as to connect the second tank and the pipe 5 to the dispensing nozzle 50 so as to be switchable, and 2b is a heat medium circulating in the jacket 2. A heat exchanger for exchanging heat, 2c is its piping, 2a is a refrigerator for cooling the inside of the heat exchanger 2b, and 2d is a heater for heating the heat medium.
[0030]
Reference numeral 8 denotes a support member provided on the lower end side of the inner wall surface 1a of the tube 1 so that the dry bulk of the liquid material that has been dried in the tube 1 does not slide downward. In the example shown in FIG. 1, the inner wall 1a is provided so as to enter and exit. However, as shown in the example shown in FIG. When the drying bulk is pushed down by the air pressure from the side, when the drying bulk is allowed to pass through, and a jet nozzle is provided on the inclined wall and the lower end of the drying bulk is gradually moved by this compressed air. In some cases, the powder is crushed and sequentially sent to the collection chamber 4.
[0031]
【The invention's effect】
As described above, the dry bulk pulverization apparatus for freeze-dried foods and chemicals according to the present invention forms a drying chamber in an upright cylindrical tube, freezes the liquid material on the inner wall surface thereof, and then under vacuum. The cylindrical recovery chamber was airtightly connected to the lower end side of the upright cylindrical tube, and the recovery chamber was pressurized by providing an exhaust port. A jet nozzle that ejects air is installed, and the dry bulk of the liquid material dried in the tube is dropped into the collection chamber and pulverized by the jet of air from the jet nozzle, and then powdered with air from the exhaust port Therefore, the liquid material can be pulverized in the body of the freeze-drying apparatus, and contamination hazards can be surely prevented and the liquid material can be pulverized.
[Brief description of the drawings]
FIG. 1 is a partially cutaway front view of an apparatus for crushing a dry bulk of a liquid material according to the means of the present invention.
FIG. 2 is a partially cutaway front view of another embodiment.
FIG. 3 is a partially cutaway front view of still another embodiment of the same.
FIG. 4 is a partially cutaway front view of a further different embodiment.
[Explanation of symbols]
F: Machine frame, W: Freeze-drying device, V1, V2, V3, V4 ... Valve, V5, V6 ... Switching valve, a ... Main part, b ... Injection port, n ... Jet nozzle, m ... Air discharge nozzle, O1・ O2 ... orifice, P2 ... pumping pump, t1 ... recovery tank, t2 ... second tank, 1 ... tube, 1a ... inner wall surface, 2 ... jacket, 2a ... refrigerator, 2b ... heat exchanger, 2c ... piping, 2d DESCRIPTION OF SYMBOLS ... Heater, 3 ... Duct, 30 ... Valve, 4 ... Collection chamber, 4a ... Exhaust port, 40 ... Main part, 41 ... Diameter expansion part 42 ... Bottom wall, 5 ... Piping, 50 ... Dispensing nozzle, 6 ... Drain Liquid pipe, 70 ... conveying cylinder, 71 ... cyclone, 72 ... pulverizer, 72a ... intake port, 8 ... support member.

Claims (5)

It consists of a drying chamber for charging the liquid material to be dried, a jacket for circulating the heat medium attached to the drying chamber, and a vacuum exhaust system equipped with a vacuum pump and a cold trap connected to the drying chamber, Freeze the liquid material to be charged in the drying chamber, sublimate the moisture in the material from the liquid material, and dry it. The drying chamber of the freeze dryer is formed as an upright cylindrical tube that freezes the liquid material on the inner wall surface. Then , a duct communicating with the vacuum exhaust system is connected to the upper end side of the tube, and a jacket for circulating the heat medium is installed on the outer periphery of the tube, and drying is completed in the tube on the lower end side of the tube. the collection chamber pointing accept dry bulk of the liquid material, forming the inner and Hobodo diameter to a larger diameter inner diameter as the cylindrical of the tube, as the axis line it aligned substantially in the axial line of the tube Coordinate and connect this An exhaust port communicating with the outside is provided at an appropriate portion of the peripheral wall of the recovery chamber, and a jet nozzle that ejects an air jet into the recovery chamber is installed on the inner surface side of the peripheral wall, and is ejected from the jet nozzle. An apparatus for crushing a dry bulk of a freeze-dried food / drug, characterized in that a dry bulk of a liquid material falling from the inside of a tube into a collection chamber by an air jet is crushed and discharged from an exhaust port. A duct leading to the vacuum exhaust system connected to the upper end of the upright cylindrical tube to form a drying oven freeze dryer So設the吐風nozzle for discharging the pressure air directed into the collection chamber through the lumen of said tube Then, the dry bulk pulverization by the jet of air from the jet nozzle provided in the recovery chamber is discharged from the air discharge nozzle and flows from the lumen of the tube through the recovery chamber to the exhaust port. The apparatus for pulverizing a dry bulk of a freeze-dried food / drug according to claim 1, wherein The main portion of the collection chamber is provided by connecting the lower end of the upright cylindrical tube to form a drying oven lyophilizer, the formed substantially corresponding cylindrical shape tube, and, on the bottom of it, the tube 2. An enlarged diameter portion having a diameter larger than the inner diameter is formed, and an exhaust port is opened to a portion that is laterally disengaged from a position immediately below the tube at a position close to the periphery of the bottom plate of the enlarged diameter portion. The dry bulk crusher for freeze-dried foods and medicines according to claim 2. An exhaust port is provided at the bottom of a cylindrical collection chamber that is connected to the lower end of an upright cylindrical tube that forms the drying cabinet of the freeze dryer , and the exhaust port is separated into powder and air by a centrifugal method. 3. A freeze-dried dry bulk pulverizer for foods and chemicals according to claim 1 or 2, wherein an intake port of a cyclone for wind selection or an intake port of a pulverizer with a cyclone is connected. At the bottom of the recovery chamber that forms the drying cabinet of the freeze dryer, the pressure air and the exhaust outlet for discharging the pulverized material are separated into powder and air by a centrifugal method. 3. A dry bulk pulverizing apparatus for freeze-dried food / drugs according to claim 1 or 2, wherein the apparatus is connected to an inlet.

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