JP3805914B2 - Pore shrinkage - Google Patents

Description

【００１３】
試験例１
実施例１及び比較例１のローションを、男性３名（２４〜３３歳）の鼻部の左右に、それぞれ５０ｍｇずつ１４日間塗布した。なお、試験開始前に鼻部、毛穴パック処理を行った。試験開始前及び終了時に鼻部写真撮影及びＤＳＡ（Ｈｉｒｏｘ社製）による６０倍鼻部拡大撮影を行い、毛穴の目立ち改善度判定及び直径、周囲長、面積変化の測定を行った。毛穴の目立ち改善度は、試験開始前及び終了時の鼻部の写真を比較し、２：改善、１：やや改善、０：変化なし、−１：やや悪化、−２：悪化、の判定基準で目視により判断し、３人の平均値として表した。また毛穴の直径、周囲長、面積変化は、試験開始前及び終了時の６０倍鼻部拡大撮影画像を画像解析ソフト（ＭＥＤＩＡ ＣＹＢＥＲＮＥＴＩＣＳ ＩＭＡＧＥ−ＰＲＯ ＰＬＵＳ Ｖｅｒ．３．０）にて解析し、各毛穴（１人当たり２０個）の試験開始前に対する終了時の平均増加率（％）を求め、３人の平均値として表した。
【００１６】
毛穴目立ち改善度は、比較例１の０に対し、実施例１は１．０であり、本発明品の鼻部での毛穴目立ち抑制効果が認められた。
【００１９】
【発明の効果】
本発明の毛穴収縮剤、毛穴目立ち抑制化粧料を用いれば、毛穴を収縮させ、または毛穴パック処理と並行処理しても毛穴拡大傾向が減少し、根本的に毛穴を目立たせなくすることができる。[0001]
BACKGROUND OF THE INVENTION
TECHNICAL FIELD The present invention relates to a pore shrinkage agent and a pore conspicuousness inhibiting cosmetic comprising the same as an active ingredient.
[0002]
[Prior art]
A pore (follicle pore) is a gap that exists between the hair and the surface of the skin, but if the pore is too large or if a black plug (a mixture of horny and sebum) enters the pore, the pore becomes noticeable. It is not preferable in appearance. Conventional methods for suppressing the conspicuous pores include methods such as concealing pores (filling, blurring, etc.) by applying cosmetics having the same color as the skin, and pore pack treatment (removing square plugs, suppressing sebum secretion, etc.).
[0003]
[Problems to be solved by the invention]
However, concealing pores does not provide a fundamental solution, and pore pack treatment is effective for removing plugs and the like, and the conspicuous pores are temporarily suppressed, but the effect is not maintained for a long time. For this reason, there has been a demand for a pore contraction agent that continuously reduces pores and makes the pores inconspicuous.
[0004]
[Means for Solving the Problems]
The inventors have found that sulfated polysaccharide effectively contracts pores. That is, this invention provides the pore shrinkage | contraction agent which uses a sulfated polysaccharide as an active ingredient, and the pore conspicuous suppression cosmetic containing this pore shrinkage agent.
[0005]
DETAILED DESCRIPTION OF THE INVENTION
The sulfated polysaccharide used in the present invention has a structure in which a part of hydroxyl groups of the polysaccharide is ester-bonded with sulfuric acid. The sulfated polysaccharide is preferably dextran sulfate, heparin and carrageenan . The sulfuric acid content in the sulfated polysaccharide is preferably 10 to 45% by weight (hereinafter simply expressed as%). The molecular weight of the sulfated polysaccharide is preferably 500,000 or less. These sulfated polysaccharides are known to have intestinal environment improving action, anticoagulant action, cartilage elasticity, strength maintaining action, etc., but were not known to have pore contraction action at all.
[0007]
The pore shrinkage agent of the present invention is a mixture of one or more of such sulfate polysaccharides. The blending amount of the sulfated polysaccharide is preferably 0.0005 to 10%, particularly preferably 0.01 to 5%.
[0008]
The pore conspicuousness-suppressing cosmetic of the present invention contains such a pore shrinkage agent and can be used as either an external preparation or an internal preparation, but an external preparation, particularly a skin external preparation, is preferred. In addition to pore shrinkage, cosmetics for suppressing the conspicuous pores include oily bases, moisturizers, UV absorbers, alcohols, chelates, pH adjusters, preservatives, thickeners, fragrances, etc. It can be produced according to a conventional method by blending pigments used for inhibition, keratoplug removers, sebum inhibitors and the like. As for the compounding quantity of the pore shrinkage agent in a pore conspicuous suppression cosmetic, 0.0005 to 5% is preferable.
[0009]
It is preferable to apply and use the cosmetic composition for suppressing pore conspicuity of the present invention on a portion of the skin where pores are particularly conspicuous, for example, the peripheral part of the nose, cheeks, forehead and the like. Further, it is more preferable to apply and use after the peel-off type pore pack treatment.
[0011]
Example 1 and Comparative Example 1
Lotions (porosity conspicuous cosmetics) with the formulation shown in Table 1 were produced according to a conventional method.
[0012]
[Table 1]

[0013]
Test example 1
The lotion of Example 1 and Comparative Example 1, the right and left nose of 3 males (24-33 years old), was applied between each 50mg by 14 days. In addition, the nose part and the pore pack process were performed before the test start. Before and after the test, nose photography and DSA (manufactured by Hirox) were used for 60-fold nose enlargement, and the degree of improvement in conspicuous pores and diameter, circumference, and area changes were measured. The degree of improvement in conspicuous pores was determined by comparing photographs of the nose before the start of the test and at the end of the test, and criteria for 2: improvement, 1: slight improvement, 0: no change, -1: slight deterioration, -2: deterioration. It was judged visually and expressed as an average value of three people . The pore diameter, perimeter, and area change were analyzed with image analysis software (MEDIA CYBERNETICS IMAGE-PRO PLUS Ver. 3.0) for 60 times nose enlarged images before and after the start of the test. The average increase rate (%) at the end of the test before (20 per person) was calculated and expressed as the average value of three persons .
[0016]
The degree of improvement in conspicuous pores was 1.0 in Comparative Example 1, while that in Example 1 was 1.0, and the effect of suppressing conspicuous pores in the nose of the product of the present invention was recognized.
[0019]
【The invention's effect】
If the pore shrinkage agent or pore conspicuousness suppressing cosmetic of the present invention is used, the pore enlargement tendency is reduced even if the pores are contracted or processed in parallel with the pore pack treatment, and the pores can be made essentially inconspicuous. .

Claims (1)

A pore contractor comprising one or more selected from the group consisting of dextran sulfate and heparin as an active ingredient.