JP3582796B2 - Cancer treatment equipment - Google Patents

Description

[0001]
[Industrial applications]
The present invention relates to a cancer treatment apparatus that emits weak ultrasonic waves toward an affected part of a cancer, thereby effectively eliminating the cancer in the affected part.
[0002]
[Prior art]
Conventionally, as a method of treating cancer by ultrasonic waves, a paper was published in which a powerful ultrasonic wave of 2 W or more per square centimeter was irradiated for 30 minutes at a temperature of 37 to 43 degrees Celsius to suppress the growth of cancer cells. (Nature Vol. 267 12 May
1977).
[0003]
By the way, since cancer cells are generally known to be weak to heat, such a cancer treatment method suppresses the growth of cancer by assisting the heating of the affected part with ultrasonic waves.
[0004]
[Problems to be solved by the invention]
However, in such a cancer treatment method, the affected area must be constantly heated or the entire body must be heated. Therefore, there is a problem that the apparatus is complicated and the cost is high. Could have a deleterious effect on normal cells.
[0005]
[Means for Solving the Problems]
The present invention provides a capsule composed of an ultrasonic transducer constituting one half of a capsule and a synthetic resin constituting the other half, and mounted in the capsule, and the ultrasonic transducer has a frequency of 20 kHz to 100 MHz. An oscillation circuit that applies an oscillation output that generates an output of 0.5 mW to 0.5 W per square centimeter from a vibration surface of the ultrasonic transducer, and an electric power applied to the oscillation circuit. A power supply for supplying, the capsule being embedded in the body, and irradiating ultrasonic waves from the capsule to treat cancer, wherein the capsule comprises two ultrasonic vibrators constituting a half capsule A capsule made of a synthetic resin; an ultrasonic vibrator attached to an inner surface of the capsule made of the synthetic resin; The ultrasonic oscillator has an oscillation output that generates an output of 0.5 mW to 0.5 W per square centimeter at a frequency of 20 kHz to 100 MHz from the vibrating surface of the ultrasonic oscillator at a frequency of 20 kHz to 100 MHz. An oscillation circuit to be applied and a power supply mounted in the synthetic resin capsule and supplying power to the oscillation circuit, the synthetic resin capsule is embedded in the body, and ultrasonic waves are irradiated from the synthetic resin capsule. And to treat cancer.
[0006]
[Action]
According to the present invention, an oscillation circuit and a power supply are mounted in a capsule composed of an ultrasonic transducer constituting a half capsule and a synthetic resin constituting the other half or two ultrasonic transducers constituting a half capsule. Or an ultrasonic oscillator, an oscillation circuit, and a power supply are mounted in a capsule made of a synthetic resin, and the frequency is 20 kHz to 100 MHz from the oscillation circuit to the ultrasonic oscillator, and the sound pressure is 1 square centimeter from the ultrasonic oscillator. Oscillation output that generates a weak ultrasonic wave of 0.5 mW to 0.5 W per unit is applied, and power is supplied to the oscillation circuit from a power supply. When weak ultrasonic waves act on the cancer cells for a time, the proliferation of the cancer cells is suppressed by the weak ultrasonic vibration, and normal cells around the cancer cells are activated.
[0007]
Therefore, in the affected area irradiated with the ultrasonic waves, the cancer cells gradually decrease and the surrounding normal cells increase.
[0008]
【Example】
The present inventors have proposed that the pigment epithelial cells of the human eye artificially cancerated by the SV40 virus gene are divided into two and proliferated under the same conditions, and the weakened continuous wave of ultrasonic waves is applied to one of the cancerated cells. Was continuously grown without irradiating ultrasonic waves to the other cancerated cells. The number of proliferation of cancerous cells without ultrasonic irradiation was as shown by the dotted line A in FIG. In contrast to the increase, the number of cancerated cells irradiated with the ultrasonic wave was suppressed by 15% on the second day, as shown by the solid line B in FIG. Decreased cancer cell growth by 31%.
[0009]
Furthermore, they found that normal cells of the pigmented epithelial cells of the chick embryo used in the comparative experiment were activated by ultrasound and increased.
[0010]
It is considered that by irradiating weakened ultrasonic waves to cancerous cells, the growth of cancer cells can be suppressed, but normal cells themselves are activated.
[0011]
Therefore, in order to obtain effective ultrasonic conditions for cancer cells, when ultrasonic waves having different frequencies and sound pressures were irradiated to the cancer cells, the sound pressure was 0.5 mW to 0.5 W per square centimeter, It has been found that ultrasonic waves having a frequency of 20 kHz to 100 MHz act very effectively on cancer cells and that the activation of normal cells is remarkable.
[0012]
FIG. 2 is a block diagram of a cancer treatment apparatus according to another embodiment of the present invention. An oscillation circuit 10 is connected to a battery 9 provided as a power supply, and the battery 9 and the oscillation circuit 10 constitute a half of a flat capsule. An ultrasonic transducer 11 to be formed and a capsule 12 made of a synthetic resin constituting the other half of the flat capsule are mounted in a capsule 13 bonded at the joint portion with an adhesive, and a frequency of 20 kHz to 100 MHz is supplied from the oscillation circuit 10. An oscillation output from the ultrasonic vibrator 11, which generates an ultrasonic wave having a sound pressure of 0.5 mW to 0.5 W per square centimeter, is applied to the ultrasonic vibrator 11 constituting one half of the capsule. Electric power is applied to the circuit 10, and the surface of the capsule 13 is coated with a material having good compatibility with the living body as needed.
[0013]
In the capsule-type cancer treatment apparatus of this embodiment configured as described above, when the oscillation circuit 10 is operated and the capsule 13 is implanted in the patient so that the ultrasonic transducer 11 faces the affected part, the ultrasonic transducer 11 moves to the affected part. Ultrasonic waves with a frequency of 20 kHz to 100 MHz and an acoustic pressure of 0.5 mW to 0.5 W per square centimeter are irradiated to suppress the growth of cancer cells in the affected area, and the capsule can be miniaturized. By simply perforating the skin surface, it can be easily implanted in the body, and the operation is simple and does not burden the patient.
[0014]
In the embodiment of FIG. 2, the half capsule 12 is made of a synthetic resin. However, this capsule 12 may be made of an ultrasonic vibrator.
[0015]
FIG. 3 is a structural view of a cancer treatment apparatus according to another embodiment of the present invention. Ultrasonic vibrators 15 and 16 are fixed to the inner surface of a synthetic resin capsule 14 at positions facing each other. A power supply 17 and an oscillation circuit 18 are mounted inside, and the output of the oscillation circuit 18 is connected to the ultrasonic vibrators 15 and 16, the frequency of the oscillation circuit 10 is 20 kHz to 100 MHz, and the sound pressure from the ultrasonic vibrators 15 and 16 is Is configured such that an oscillation output of generating an ultrasonic wave of 0.5 mW to 0.5 W per square centimeter is applied to the ultrasonic vibrators 15 and 16, and power is applied from the battery 9 to the oscillation circuit 10. I have.
[0028]
The present embodiment having such a configuration also has the same effect as the embodiment of FIG. 2 described above, and in the embodiment of FIG. 3, two ultrasonic transducers 15 and 16 are provided to face each other. Two or more ultrasonic transducers may be provided so that ultrasonic waves are generated from other parts.
[0029]
【The invention's effect】
As described above, in the present invention, by irradiating a patient with cancer cells with weak ultrasonic waves for a long time, the growth of cancer cell cancer is reliably suppressed, and normal cells near the affected area are activated. The advantage is that
[Brief description of the drawings]
FIG. 1 is a diagram comparing the growth of cancer cells irradiated with ultrasonic waves and that of non-irradiated cancer cells in order to explain the method of the present invention.
FIG. 2 is a configuration diagram of a cancer treatment apparatus according to an embodiment of the present invention.
FIG. 3 is a configuration diagram of a cancer treatment apparatus according to another embodiment of the present invention.
[Explanation of symbols]
Reference Signs List 9 Battery 10 Transmitter 11 Capsule-shaped ultrasonic transducer 12 Capsule made of synthetic resin 13 Capsule 14 Capsule made of synthetic resin 15, 16 Ultrasonic transducer 17 Power supply 18 Oscillation circuit

Claims (3)

A capsule made up of an ultrasonic vibrator constituting one half of the capsule and a synthetic resin constituting the other half, and mounted in the capsule, and the ultrasonic vibrator is provided with the ultrasonic vibrator at a frequency of 20 kHz to 100 MHz. An oscillating circuit for applying an oscillating output that generates an output of 0.5 mW to 0.5 W per square centimeter from the vibrating surface of the vibrator; a power supply mounted in the capsule and supplying power to the oscillating circuit; A cancer treatment apparatus, wherein the capsule is embedded in a body, and the capsule is irradiated with ultrasonic waves to treat cancer. 2. The cancer treatment apparatus according to claim 1, wherein the capsule is constituted by two ultrasonic transducers constituting a half capsule. A capsule made of a synthetic resin, an ultrasonic vibrator mounted facing the inner surface of the synthetic resin capsule, and a frequency of 20 kHz to 100 MHz mounted in the synthetic resin capsule. An oscillation circuit for applying an oscillation output that generates an output of 0.5 mW to 0.5 W per square centimeter from a vibration surface of the ultrasonic transducer, and an oscillation circuit mounted in the synthetic resin capsule, A cancer treatment apparatus comprising a power supply for supplying power to a circuit, wherein the capsule of the synthetic resin is embedded in a body, and is irradiated with ultrasonic waves from the capsule of the synthetic resin to treat cancer.

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