CN110090364B - Wall-attached charging type ultrasonic positive inotropic treatment device - Google Patents
Wall-attached charging type ultrasonic positive inotropic treatment device Download PDFInfo
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- CN110090364B CN110090364B CN201910362076.1A CN201910362076A CN110090364B CN 110090364 B CN110090364 B CN 110090364B CN 201910362076 A CN201910362076 A CN 201910362076A CN 110090364 B CN110090364 B CN 110090364B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
Abstract
The invention discloses an adherence charging type ultrasonic positive inotropic therapy device, which comprises an ultrasonic irradiation probe, an integrated module and a charging type display control panel which are sequentially and electrically connected; an inverter and an ultrasonic generator which are electrically connected are embedded in the integrated module; an ultrasonic transducer is embedded in the ultrasonic irradiation probe; the ultrasonic transducer is electrically connected with the ultrasonic generator; the ultrasonic transducer comprises a plurality of piezoelectric crystals, the piezoelectric crystals are circularly and radially distributed on the bendable flaky body, and the piezoelectric crystals are connected in series by a lead; the upper surface and the lower surface of the piezoelectric crystal are both connected with the electrodes; the lower end of the piezoelectric crystal is sequentially provided with a matching layer and a sound transmission window; a temperature sensor connected with the display controller is embedded in the center of the inner edge of the sound-transmitting window; the charging display control panel is provided with a plurality of control keys connected with the display controller.
Description
Technical Field
The invention belongs to the technical field of medical devices, and particularly relates to an adherence charging type ultrasonic positive inotropic therapy device.
Background
Research shows that the ultrasonic irradiation has the function of changing the permeability of cell membranes of cardiac muscle and skeletal muscle and the ion transport channels related to muscle strength, thereby affecting the depolarization and repolarization processes of the cell membranes of the cardiac muscle and the skeletal muscle and the Ca related to the muscle strength in cells++Ion concentration distribution and influence the myofibrillar contractile function in cardiac and skeletal muscle cells and lead to different muscle strength changes. With ultrasonic irradiation it is possible to produce two opposite muscle force effects, namely: it can not only enhance the contractile function of cardiac muscle and skeletal muscle cells, but also reduce the contractile function of cardiac muscle and skeletal muscle cells.
The existing ultrasonic positive inotropic therapy device can not be tightly attached to the irradiated body part, so that the ultrasonic attenuation is caused, and the treatment effect is far from the expectation.
Disclosure of Invention
The present invention aims to solve or improve the above problems by providing an adherence-charged ultrasonic positive inotropic therapy device.
In order to achieve the purpose, the invention adopts the technical scheme that:
an adherence charging type ultrasonic positive inotropic treatment device comprises an ultrasonic irradiation probe, an integration module and a charging type display control panel which are sequentially and electrically connected through a USB data drive line;
an inverter and an ultrasonic generator which are electrically connected are embedded in the integrated module; an ultrasonic transducer is embedded in the ultrasonic irradiation probe; the ultrasonic transducer is electrically connected with the ultrasonic generator; a display controller and a rechargeable power supply are integrated in the rechargeable display control panel; the display controller is respectively connected with the ultrasonic generator and the rechargeable power supply;
the ultrasonic transducer comprises a plurality of piezoelectric crystals, the piezoelectric crystals are circularly and radially distributed on the bendable flaky body, and the piezoelectric crystals are connected in series by a lead; the upper surface and the lower surface of the piezoelectric crystal are both connected with the electrodes; the lower end of the piezoelectric crystal is sequentially provided with a matching layer and a sound transmission window; a temperature sensor connected with the display controller is embedded in the center of the inner edge of the sound-transmitting window; the charging display control panel is provided with a plurality of control keys connected with the display controller.
Preferably, the display controller is an ARM processor.
Preferably, the end part of the ultrasonic irradiation probe is uniformly filled with sound absorption material.
Preferably, the sound-transmitting window is a convex lens or a concave lens.
Preferably, at least one matching layer is arranged below the piezoelectric crystal.
Preferably, the temperature sensor is a KW-WDCGQ miniature temperature sensor with the size of 0.5mm multiplied by 0.5 mm.
Preferably, the frequency of the ultrasonic wave emitted by the inverter, the ultrasonic generator and the ultrasonic transducer is 3.6Mhz-5Mhz, and the intensity is 1w/cm2-3w/cm2。
The adherent charging type ultrasonic positive inotropic treatment device provided by the invention has the following beneficial effects:
the ultrasonic transducer is independently arranged in the ultrasonic irradiation probe, and the plurality of piezoelectric crystals are annularly distributed on the concentric circle, so that the feasibility of freely adjusting the three-dimensional curved surface of the irradiated part of the human body is improved, and the device is more convenient to fix on the surface of the part of the body to be treated so as to be convenient for continuous treatment; meanwhile, the ultrasonic irradiation probe is tightly attached to the body part to be irradiated, so that the ultrasonic attenuation is reduced, and the treatment effect is improved.
Drawings
Fig. 1 is a structural diagram of an adherence charging type ultrasonic positive inotropic treatment device.
Fig. 2 is a schematic block diagram of an adherence charging type ultrasonic positive inotropic treatment device.
Fig. 3 is a schematic block diagram of an adherence charging type ultrasonic positive inotropic treatment device.
Fig. 4 is a chart of experimental results of beagle open-chest ultrasonic irradiation of the anchorage-dependent charging type ultrasonic positive inotropic therapy device.
Fig. 5 is an in vitro irradiation experiment of basic myocardial cells of an adherence charging type ultrasonic positive inotropic therapy device.
Fig. 6 is an in vitro skeletal muscle group irradiation experiment of an adherence charging type ultrasonic positive inotropic therapy device.
Fig. 7 is an adherent charging type ultrasonic positive inotropic therapy device beagle open chest in vivo heart ultrasonic irradiation experiment.
Wherein, 1, ultrasonic transducer; 2. an ultrasonic generator; 3. a display controller; 4. a temperature sensor; 5. an inverter; 6. a rechargeable power supply; 7. an integration module; 8. a wire; 9. a USB data drive line; 10. a sound absorbing material; 11. an electrode; 12. a piezoelectric crystal; 13. a matching layer; 14. an acoustic window; 15. charging type display control panel.
Detailed Description
The following description of the embodiments of the present invention is provided to facilitate the understanding of the present invention by those skilled in the art, but it should be understood that the present invention is not limited to the scope of the embodiments, and it will be apparent to those skilled in the art that various changes may be made without departing from the spirit and scope of the invention as defined and defined in the appended claims, and all matters produced by the invention using the inventive concept are protected.
According to an embodiment of the present application, referring to fig. 1, the wall-attached rechargeable ultrasonic positive inotropic therapy device of the present scheme includes an ultrasonic irradiation probe, an integrated module 7 and a rechargeable display control panel 15, which are sequentially and electrically connected through a USB data driving wire 9, wherein the USB data driving wire 9 is used for supplying power and transmitting data.
The integrated module 7 can be fixed on the back of the rechargeable display control panel 15, or the rechargeable display control panel 15 is fixed on the integrated module 7, and the two structures are fixed together for carrying and operation.
Meanwhile, the ultrasonic irradiation probe is independent into a single structure, so that the weight of the equipment can be effectively reduced, the ultrasonic irradiation probe is in close contact with a back irradiation patient, the attenuation of ultrasonic waves is avoided, and the ultrasonic irradiation probe cannot be pressed on the patient too heavily. The operation is convenient, and the therapeutic effect of the ultrasonic wave is also improved.
The ultrasonic irradiation probe, the integrated module 7, and the charging-type display control panel 15 are described in detail below.
Referring to fig. 3, an ultrasonic transducer 1 is embedded in the ultrasonic irradiation probe through a PCB board, and an inverter 5 and an ultrasonic generator which are electrically connected are embedded in an integrated module 7; the ultrasonic transducer 1 is electrically connected to the ultrasonic generator.
The display controller 3 and the charging power supply 6 are integrated in the charging display control panel 15; the display controller 3 is respectively connected with the ultrasonic generator 2 and the rechargeable power supply 6; the input end of the ultrasonic generator 2 is sequentially connected with the inverter 5 and the rechargeable power supply 6, and the output end of the ultrasonic generator is connected with the ultrasonic transducer 1.
Referring to fig. 2, the ultrasonic transducer 1 includes a plurality of piezoelectric crystals 12, the plurality of piezoelectric crystals 12 are annularly distributed on at least two concentric circles, each piezoelectric crystal 12 is circularly and radially distributed on a bendable sheet-shaped body, and the piezoelectric crystals 12 are connected in series by a wire 8.
The circular piezoelectric crystals 12 are selected and arranged in an annular shape, so that the feasibility of freely adjusting the three-dimensional curved surface of the irradiated part of the human body is improved, and the device is more convenient to fix on the surface of the part of the body to be treated so as to be convenient for continuous treatment; meanwhile, the ultrasonic irradiation probe is tightly attached to the body part to be irradiated, so that the ultrasonic attenuation is reduced, and the treatment effect is improved.
The piezoelectric crystal 12 is one of core elements for emitting ultrasonic waves, and is cut out in a certain manner and in a certain direction from a piezoelectric single crystal or is made of piezoelectric ceramics through polarization.
The upper and lower surfaces of the piezoelectric crystal 12 are connected with the electrodes 11, the electrodes 11 are silver layers covered on the two surfaces of the piezoelectric crystal 12, in order to make the voltage supplied to the piezoelectric crystal 12 uniform, the electrodes 11 on the upper surface of the piezoelectric crystal 12 are connected with the live wire to lead to the circuit, and the ground wire is connected with the common point of the circuit on the bottom surface to form a loop.
The lower end of the piezoelectric crystal 12 is provided with a matching layer 13 and an acoustic window 14 in sequence. The sound-transmitting window 14 is a convex lens or a concave lens, and is used for focusing beams emitted by the ultrasonic transducer 1 to meet specific requirements of ultrasonic irradiation parts.
At least one matching layer 13 is arranged, the number of the layers is determined according to the actual situation, and one or more matching layers 13 are required to be added in front of the wafer in order to solve the acoustic matching between the skin and the piezoelectric crystal 12 material due to the large difference of the acoustic characteristic impedance of the skin of a human body and the piezoelectric crystal 12 material.
The sound absorption material 10 is uniformly filled on the shell of the probe, the sound absorption material 10 is closed-cell foam plastic, and the sound energy radiated backwards is almost completely absorbed so as to eliminate backward interference. The sound absorbing material 10 is also a damping material for the vibration of the piezoelectric crystal 12 to shorten the vibration period.
A temperature sensor 4 connected with the display controller 3, wherein the temperature sensor 4 is a KW-WDCGQ micro temperature sensor 4 with the size of 0.5mm multiplied by 0.5mm, is embedded in the center of the inner edge of the sound-transmitting window 14.
During ultrasonic irradiation, a portion of the acoustic energy is converted to thermal energy due to attenuation of the energy during the transmission of the acoustic waves, resulting in an increase in the temperature of the cardiac and skeletal muscles. Previous studies have shown that the contractile performance of cardiac and skeletal muscles can be improved when ultrasound-generated energy is used to improve differential heating in the range of biological activities (<44 ℃). When the ultrasonic wave continuously irradiates the cardiac muscle and the skeletal muscle, the cardiac muscle and the skeletal muscle can be continuously heated. Ultrasonic irradiation can produce side effects if the myocardial and skeletal muscle temperatures continue to increase above a certain threshold. Therefore, the KW-WDCGQ micro temperature sensor 4 is adopted to monitor the change of the temperature in real time, the temperature is controlled in a biological activity safety range, and the safety condition which needs to be considered in ultrasonic irradiation treatment is provided.
In the ultrasonic irradiation treatment process, the temperature sensor 4 can monitor the temperature of the contact position of the ultrasonic irradiation probe and the surface of a human body in real time, meanwhile, the temperature threshold is set through the display control panel, once the temperature exceeds the threshold, the alarm is given through the display screen on the rechargeable display control panel 15, the alarm mode can give out alarm sound through the built-in loudspeaker, meanwhile, the display screen flickers to warn that the current temperature value exceeds the preset value, the ultrasonic treatment should be stopped in time, and the temperature is known to be reduced to the range value of the normal temperature.
The charging display control panel 15 is provided with a plurality of control keys connected with the display controller 3. Wherein, the display controller 3 is an ARM processor.
A plurality of control keys are embedded or integrated on the charging display control panel 15, including a power switch, an irradiation start and stop switch, an irradiation time setting key, an ultrasonic emission frequency adjusting key, an ultrasonic power adjusting key and a threshold temperature setting.
In the irradiation treatment process, after the charging display controller 33 is started, the irradiation time, the emission frequency, the emission power and the threshold temperature are all set as default values, and parameters such as the irradiation time, the emission frequency and the threshold temperature can be set respectively if special requirements exist.
Wherein, the frequency of the ultrasonic wave emitted by the inverter 55, the ultrasonic generator 22 and the ultrasonic transducer 11 is 3.6Mhz to 5Mhz, and the intensity is 1w/cm2-3w/cm2。
The device of the invention mainly aims at patients with special requirements to carry out ultrasonic irradiation treatment on cardiac muscle and skeletal muscle for a long time through the body surface so as to achieve the purpose of enhancing the contraction function of the cardiac muscle and the skeletal muscle. The function principle is that when the ultrasonic wave is changedWhen the ultrasonic waves emitted by the energy device are adjusted to have sufficient energy to penetrate the heart muscle and bone, the function of the sound waves can be exerted by producing low temperature heating, microcirculation changes, excitation, stable cavitation, microflow or chemical effects, etc. Due to this known property of ultrasound, myocardial and skeletal muscle tissue will absorb this differential heating according to their own viscosity. Thus, the cell membranes within the myocardium and skeletal muscle can absorb more energy than the cytoplasm. Thus, the sarcoplasmic reticulum in the heart and skeletal muscle cells will absorb energy and be heated in preference to the cytoplasm. Thereby causing the cell membrane permeability and myodynamia ion transport channel function of the cardiac muscle and the skeletal muscle to be changed, affecting the process of depolarization and repolarization of the cell membrane of the cardiac muscle and the skeletal muscle and the Ca related to the myodynamia in the cell++Ion concentration distribution. It is this biological effect that affects the contractile function of myofibrils in cardiac and skeletal muscle cells and leads to different muscle strength changes.
The ultrasonic irradiation device is mainly characterized in that specific ultrasonic irradiation parameters are adopted to carry out ultrasonic irradiation treatment on cardiac muscle or skeletal muscle to induce positive muscle strength of the cardiac muscle and the skeletal muscle.
Because the action difference of positive muscle force of cardiac muscle and skeletal muscle induced by different ultrasonic irradiation frequencies and different ultrasonic powers is larger, the ultrasonic irradiation with improper frequency and power can play opposite roles, and even the muscle force of cardiac muscle and skeletal muscle is reduced. Therefore, the selection of the ultrasonic irradiation frequency, the sound wave intensity and the irradiation time is crucial to the ultrasonic irradiation treatment. Experiments prove that the optimal sound wave frequency of the positive inotropic force of the cardiac muscle and the skeletal muscle induced by ultrasonic irradiation is 3.6Mhz to 5Mhz, and the sound wave intensity is 1w/cm2-3w/cm2Irradiation time (4min-6min), temperature threshold of 37 ℃ and the like.
Referring to fig. 4-7, the ultrasonic irradiation parameters provided by the present invention are used to prove that the left ventricular contraction function is most obviously enhanced, the aortic blood flow is increased, the overall heart work is improved, and the method is more favorable for inducing cardiac muscle and skeletal muscle to generate positive muscle force and simultaneously reducing the possibility of generating negative muscle force through the basic myocardial cell in vitro irradiation experiment, the isolated skeletal muscle group irradiation experiment and the beagle open chest in vivo heart ultrasonic irradiation experiment.
According to one embodiment of the present application, the following is a method of using the adherently charged ultrasonic positive inotropic treatment device of the present invention:
And 2, the medical care personnel hold the ultrasonic irradiation probe to irradiate the body part to be irradiated and treated, and the ultrasonic wave continuously irradiates cardiac muscle and skeletal muscle, so that the temperature of the skin on the surface of the medical care personnel continuously rises.
And 3, when the temperature exceeds a set threshold value, alarming is carried out on the rechargeable display control panel 15, the medical staff stops irradiating the cardiac muscle and the skeletal muscle (or stops generating ultrasonic waves under the control of the display controller 3), and the ultrasonic irradiation is continuously started until the temperature is reduced to be within a normal temperature range.
The ultrasonic irradiation probe is independent into a single structure, so that the weight of equipment can be effectively reduced, the ultrasonic irradiation probe is in close contact with a back irradiation patient, the attenuation of ultrasonic waves is avoided, and the ultrasonic irradiation probe cannot be pressed on the patient too heavily. The operation is convenient, and the therapeutic effect of the ultrasonic wave is also improved.
The ultrasonic transducer 1 is independently arranged in the ultrasonic irradiation probe, and the plurality of piezoelectric crystals 12 are annularly distributed on the concentric circle, so that the feasibility of freely adjusting the three-dimensional curved surface of the irradiated part of the human body is improved, and the device is more convenient to fix on the surface of the part of the human body to be treated so as to be convenient for continuous treatment; meanwhile, the ultrasonic irradiation probe is tightly attached to the body part to be irradiated, so that the ultrasonic attenuation is reduced, and the treatment effect is improved.
While the embodiments of the invention have been described in detail in connection with the accompanying drawings, it is not intended to limit the scope of the invention. Various modifications and changes may be made by those skilled in the art without inventive step within the scope of the appended claims.
Claims (1)
1. An adherence charging type ultrasonic positive inotropic treatment device is characterized in that: the ultrasonic irradiation probe, the integrated module and the rechargeable display control panel are sequentially and electrically connected through a USB data drive wire;
an inverter and an ultrasonic generator which are electrically connected are embedded in the integrated module; an ultrasonic transducer is embedded in the ultrasonic irradiation probe; the ultrasonic transducer is electrically connected with the ultrasonic generator; a display controller and a rechargeable power supply are integrated in the rechargeable display control panel; the display controller is respectively connected with the ultrasonic generator and the rechargeable power supply;
the ultrasonic transducer comprises a plurality of piezoelectric crystals, the piezoelectric crystals are circularly and radially distributed on the bendable flaky body, and the piezoelectric crystals are connected in series by a lead; the upper surface and the lower surface of the piezoelectric crystal are both connected with electrodes; the lower end of the piezoelectric crystal is sequentially provided with a matching layer and a sound transmission window; a temperature sensor connected with a display controller is embedded in the center of the inner edge of the sound-transmitting window; the rechargeable display control panel is provided with a plurality of control keys connected with the display controller;
the circular piezoelectric crystals 12 are arranged in an annular shape, so that the feasibility of freely adjusting the three-dimensional curved surface of the irradiated part of the human body is improved, and the device is more convenient to fix on the surface of the part of the body to be treated so as to be convenient for continuous treatment; meanwhile, the ultrasonic irradiation probe is tightly attached to the body part to be irradiated, so that the ultrasonic attenuation is reduced, and the treatment effect is improved;
the piezoelectric crystal 12 is one of core elements, is used for transmitting ultrasonic waves, and is formed by cutting a piezoelectric single crystal in a certain mode and a certain direction or is formed by polarizing piezoelectric ceramics;
the upper and lower surfaces of the piezoelectric crystal 12 are both connected with the electrode 11, the electrode 11 is a silver layer covered on both surfaces of the piezoelectric crystal 12, in order to make the voltage supplied to the piezoelectric crystal 12 uniform, the electrode 11 on the upper surface of the piezoelectric crystal 12 is connected with the live wire to lead to the circuit, the ground wire is connected with the common point of the circuit so as to form a loop on the bottom surface;
the electrodes 11 are silver layers covered on two sides of the piezoelectric crystal 12, in order to make the voltage supplied to the piezoelectric crystal 12 uniform, the electrodes 11 on the upper surface of the piezoelectric crystal 12 are connected with the live wire to lead to the circuit, and the ground wire is connected with the common point of the circuit on the bottom surface to form a loop;
the sound absorption material 10 is uniformly filled on the shell of the probe, the sound absorption material 10 is closed-cell foam plastic, and the sound energy radiated backwards is almost completely absorbed so as to eliminate backward interference; the sound absorbing material 10 is also a damping material of the vibration of the piezoelectric crystal 12 to shorten the vibration period;
the display controller is an ARM processor;
the end part of the ultrasonic irradiation probe is uniformly filled with sound absorption materials;
the sound transmission window is a convex lens or a concave lens;
at least one matching layer is arranged below the piezoelectric crystal;
the temperature sensor is a KW-WDCGQ micro temperature sensor, and the size of the temperature sensor is 0.5mm multiplied by 0.5 mm;
the frequency of the ultrasonic wave emitted by the inverter, the ultrasonic generator and the ultrasonic transducer is 3.6Mhz to 5Mhz, and the intensity is 1w/cm2-3w/cm2。
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