JP3533721B2 - Cosmetics - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic composition containing betaine and carrageenan, having a high softening effect and a moisturizing effect, satisfying an excellent feeling of use, and having high durability.

[0002]

2. Description of the Related Art The stratum corneum, which is the outermost layer of skin, tends to dry under weather conditions such as low temperature and low humidity in winter, so that the skin becomes bulky or rough. Excessive use of detergents and solvents also makes the skin bulky and rough. Such roughening and roughness of the skin is caused by the loss of a water-absorbing water-soluble component called NMF (natural moisturizing factor) in the stratum corneum, the decrease in moisture in the stratum corneum, and the softness of the stratum corneum. It is thought to be caused by loss of sex.

[0003] For this reason, conventionally, in cosmetics intended to soften the skin, a large amount of water is given to the stratum corneum,
And in order to keep the applied moisture for a long time,
Various moisturizing ingredients are blended. In particular, since the NMF component contains an organic acid (carboxylic acid), amino acid, urea, etc., various organic acids, amino acids or urea are blended in the cosmetic to replenish the lost NMF component to the skin. That is being done.

For example, as a compound containing an organic acid as one of the NMF components, a compound utilizing the softening action of the stratum corneum of α-oxyacid has been proposed (JP-A-55-19).
291). However, the resulting softening effect is temporary and not permanent. In addition, there is a disadvantage that the pH at which the α-oxyacid exerts the softening action of the stratum corneum is in a low range (pH 2 to 4) where normal skin physiology is inhibited.

[0005] On the other hand, there has been reported an example in which an alkali such as sodium hydroxide, potassium hydroxide, triethanolamine or the like is added to a solution of an α-oxy acid in order to utilize the α-oxy acid in a neutral pH range. Have been. However, when a large amount of alkali is added, the stability of the solution is reduced, and it becomes difficult to maintain the cosmetic at a stable quality. In addition, since the preferred natural pH of the skin is weakly acidic, about 4 to 6, the use of a large amount of alkali is rather harmful to the skin. Furthermore, it has been reported that prolonged continuous use of amines causes an allergic reaction. For this,
It has been proposed to use a basic amino acid as the alkali to be used in combination with the α-oxyacid (Japanese Patent Application Laid-Open No. 58-8 / 1983).
007 publication).

[0006] It has also been proposed to mix succinic acid or a salt thereof as an organic acid of the NMF component in cosmetics together with urea and amino acids (Japanese Patent Laid-Open No. 5-163129).

[0007] Furthermore, it is reported that as a component using an amino acid or a derivative thereof as one of the NMF components, a protein hydrolyzate such as yoquinin or a certain peptide has a moisturizing effect and a softening effect ( JP-A-62-99315, JP-A-2-178207).

[0008] In addition, as a moisturizer or softener,
In addition to the NMF-related components as described above, water-soluble polyhydric alcohols, especially propylene glycol and a molecular weight of 200 to 40
About 0 polyethylene glycol is widely used.

In addition, since betaine has an effect of increasing the turnover speed of the stratum corneum and preventing skin roughness, it has been proposed to incorporate it into cosmetics (Japanese Patent Laid-Open No. 1-2).
No. 75511).

[0010]

However, the conventional NMF-related components such as the above-mentioned organic acids such as α-oxy and amino acids or derivatives thereof have a sticky feeling, and therefore, the cosmetics containing these compounds cannot be used. Has a problem that a satisfactory feeling of use cannot be obtained.

Water-soluble polyhydric alcohols such as propylene glycol and polyethylene glycol need to be incorporated in a large amount in cosmetics in order to obtain a sufficient moisturizing effect.
In that case, there is a problem that a sticky feeling is generated.
In addition, there was concern about the use of a large amount in terms of safety (allergy).

[0012] As for betaine, cosmetics containing it have an excellent moisturizing effect, but it has been desired to improve moistness, smoothness or smoothness in use. .

The present invention is to solve the above-mentioned problems of the prior art, and has a moisturizing effect, a moist feeling,
It is an object of the present invention to provide a cosmetic which improves both smoothness and smoothness in use and further enhances their sustainability.

[0014]

Means for Solving the Problems The present inventors have found that by blending betaine and carrageenan together in cosmetics,
Greater softening effect and moisturizing effect than when betaine is used alone can be obtained, and cosmetics can be made moderately viscous in a weakly acidic region that is favorable for the skin, giving a moist feeling, a smooth feeling, or a smooth feeling. They have found that they can be greatly improved, and have completed the present invention.

That is, the present invention provides glycine betaine 0.0
Containing a 1 to 10% by weight and carrageenan 0.01 to 10 wt%, pH provides a 4.0-6.0 Der Ru cosmetics.

Hereinafter, the present invention will be described in detail.

The cosmetic of the present invention contains both betaine and carrageenan as essential components. Here, betaine includes N-trialkyl substitution of various amino acids.
Body, for example, glycine betaine, γ-butyrobetaine,
Homarine, trigonelline, beta-alanine betaine, carnitine, homoserine betaine, Ant Pureu phosphorus, valine betaine, lysine betaine, ornithine betaine, alanine betaine, Taurobetain, Sutakidorin, glutamic betaines, such as phenylalanine betaine ani
In the present invention, glycine betaine is used.
Need to be used. By using glycine betaine
This is preferable because a greater softening effect can be obtained. Commercially available products can be used as such betaine, and for example, amino coat manufactured by Asahi Foods Co., Ltd. can be used as glycine betaine. In the present invention, grayed
In addition to ricin betaine, one type of other betaine may be used, or a plurality of types may be used in combination.

The content of betaine in the cosmetic is not particularly limited, but is usually 0.01 to 10% by weight.
If it is less than 0.01% by weight, it is difficult to obtain a sufficient moisturizing effect and softening effect, and even if it exceeds 10% by weight, it is not possible to obtain a moisturizing effect and softening effect according to the compounding amount.

On the other hand, the carrageenan used in the present invention is a natural polysaccharide, and includes κ-carrageenan, ι-carrageenan, λ-carrageenan, etc., depending on the raw materials and extraction method.
In the present invention, any of them can be used. Also, one kind of carrageenan may be used,
A plurality of types may be used together. From the viewpoint of improving the feeling of use of the cosmetic, it is preferable to use ι-carrageenan having a large thickening effect.

The content of carrageenan in the cosmetic is not particularly limited, and can be appropriately adjusted according to the dosage form of the cosmetic.
The content is preferably set to 10 to 10% by weight, more preferably 0.05 to 3% by weight.

In the present invention, it is preferable that betaine and carrageenan are contained as described above, and that the pH is weakly acidic, which is about 4.0 to 6.0, which is the original pH of the skin. This makes it possible to maintain the skin in a normal state. In addition, it is possible to suppress ceramidase activity, suppress degradation of ceramide (an intercellular lipid that plays an important role in moisturizing the skin), and maintain a moist state of the skin. In addition, when the pH is set in such a range, the conventional cosmetics containing no carrageenan cannot be adjusted to an appropriate viscosity, and satisfy the moist feeling, smooth feeling, or feeling of use such as smoothness. Although it could not be obtained, carrageenan has a high thickening action in such a pH range, so that in the present invention, a preferable viscosity and a feeling of use can be obtained. In the present invention,
In order to adjust the pH of the cosmetic to such a range, a phosphate buffer, a succinate buffer, or the like can be used.

The cosmetic of the present invention can further contain various components in addition to betaine and carrageenan.

For example, an acidic polysaccharide derived from a callus culture of a plant belonging to the genus Polyanthes can be contained. This is preferable because the moisturizing effect and the softening effect of the cosmetic can be improved. This acidic polysaccharide is described in the claims of JP-A-64-10997 and Japanese Patent Publication No. 5-29329, and its production method is, for example, tuberose as an acidic polysaccharide. -Polysaccharide: When TPS is obtained, Linsmeier-
Callus was induced using a medium supplemented with 10 ⁻⁵ M auxin and 10 ⁻⁶ M cytokinin as plant hormones in Skoog's basal medium, and 3% sucrose as a carbon source. The culture is further performed with shaking using a liquid medium containing the same components as the callus culture medium. Thereafter, the culture solution is concentrated using a rotary evaporator or the like, and a solvent such as ethanol or acetone is added to the concentrated solution.
Separate and acquire PS.

The mixing ratio of such an acidic polysaccharide is usually preferably 0.0001 to 10% by weight of the cosmetic, more preferably 0.001 to 5% by weight. If the compounding ratio is less than 0.0001% by weight, the effect is not sufficiently exhibited, which is not preferable.

Further, the cosmetic of the present invention can contain at least one of carboxylic acid, amino acid and urea, which are NMF components, whereby the moisturizing effect and the softening effect can be improved. It is preferred.

As the carboxylic acid, various monocarboxylic acids or polycarboxylic acids such as di- or tricarboxylic acids can be used. Among them, dicarboxylic acids such as succinic acid, malic acid and tartaric acid, citric acid It is preferable to include a tricarboxylic acid such as an acid, and it is particularly preferable to include succinic acid.

The amino acids include H ₂ N (CH ₂ )
_n COOH (n = 3-9), lysine, histidine, arginine, ornithine, canavanine, glutamic acid, aspartic acid, serine, alanine, glycine, leucine,
Amino acids and salts thereof such as isoleucine, proline, threonine, valine, methionine, cystine, cysteine, and hydroxyproline can be given, among which basic amino acids such as lysine, histidine and arginine are preferable, and arginine is particularly preferable from the viewpoint of flexibility. preferable.
In addition, the mixing ratio of the basic amino acid is preferably basic amino acid: betaine = 1: 0.01 to 99 in terms of the weight ratio of betaine to the cosmetic.

In the present invention, if necessary, other humectants, thickeners, preservatives, surfactants, oils, antioxidants,
Chelating agents, ultraviolet absorbers, powders, pigments, medicinal ingredients, fragrances, etals, purified water, and the like can be contained within a range that does not impair the effects of the present invention.

The cosmetic of the present invention is not particularly limited in terms of dosage form, and can be formed into lotions, emulsions, creams, packs, jellies, foundations and the like.
In addition, various phase modes such as a homogeneous solution system, an emulsion system, and a two-layer system can be adopted. In this case, the production method can be a conventional method.

[0030]

The cosmetic of the present invention containing both betaine and carrageenan has significantly improved moisturizing and softening effects as compared to the case of containing them alone.

The carrageenan used in the present invention has a high concentration of betaine and other components in the cosmetic even in the weakly acidic region of about 4.0 to 6.0, which is the original pH of the skin. Even in such a case, the cosmetic of the present invention can be adjusted to a desired viscosity because it exhibits a stable and high thickening action. In addition, the use of carrageenan greatly improves the moist feeling, smooth feeling, or smoothness of use, and furthermore, these effects last for a long time.

[0032]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be specifically described below based on embodiments.

Example 1 and Comparative Examples 1 and 2 The components shown in Table 1 were blended according to a conventional method to produce lotions of Examples and Comparative Examples.

The softening effect of the obtained lotion was evaluated as follows. First, the human forearm was washed with soap, and the vibration frequency was measured with a tactile sensor (temperature 22).
° C, humidity 75%), then apply lotion 5 μm / cm ²
And left for 1 hour, the vibration frequency was measured again, and the frequency change before and after application was determined.

Table 1 shows the results. In the table, it is shown that the greater the frequency change is, the greater the flexibility effect is. From this result, 0.70% by weight of betaine
It can be seen that the lotion of Example 1 containing 0.25% by weight of carrageenan and carrageenan has a greater softening effect than the lotion of the comparative example not containing betaine or carrageenan.

[0036]

[Table 1] (Unit:% by weight) Example 1 Comparative Example 1 Comparative Example 2 Betaine * a 0.07-0.70 ι-carrageenan * b 0.20 0.25-κ-carrageenan * c 0.05--TPS 2.00 2.00 2.00 Arginine 1.00 1.00 1.00 Amber Acid 1.00 1.00 1.00 Glycerin 5.00 5.00 5.00 Disodium monohydrogen phosphate 1.00 1.00 1.00 Urea 1.00 1.00 1.00 Purified water Balance Balance Balance pH 4.0 4.0 4.0 Frequency change (Hz) -155 -32 -58 (Note) * a Glycine betaine, amino coat manufactured by Asahi Kasei Kogyo Co., Ltd. * b l-carrageenan, Soagina MV320 manufactured by Mitsubishi Rayon Co., Ltd. * c κ-carrageenan, soagina MV101 manufactured by Mitsubishi Rayon Co., Ltd. Comparative Examples 3 to 11 The components shown in Tables 2 and 4 were blended by a conventional method to produce lotions of Examples and Comparative Examples.

Then, the initial pH of the obtained lotion was measured. In addition, (i) moist feeling,
(ii) smoothness, (iii) smoothness, (iv) non-stickiness, (v) smoothing effect, based on the judgment of good or bad when 20 specialized panelists applied to the face, according to the following evaluation criteria: The evaluation was performed on a scale (◎, △, Δ, ×). further,
(vi) Persistence of smoothness and (vii) Persistence of smoothness were similarly evaluated in four steps based on the judgment by a specialized panelist according to the following criteria. The results are shown in Tables 5 to 7.

[Evaluation criteria for feeling of use] ◎: 15 to 20 persons judged good in use ：: 10 to 14 persons judged that the usability was good Δ: 5 to 9 persons judged good feeling of use ×: Less than 4 people judged good feeling of use [Sustainability evaluation criteria] ◎: 15 to 20 persons judged that the feeling of use was persistent ：: 10 to 14 persons judged that the feeling of use was persistent Δ: 5 to 9 persons determined that the feeling of use was persistent. ×: 4 or less judged that the feeling of use was persistent.

[0039]

[Table 2] Ingredients Example (% by weight) 2 3 4 5 6 7 8 9 κ-Karachidanan 0.20--0.20 0.20 0.05-0.05 ι-Karachidanan-0.20-0.05-0.20 0.20-λ-Karachidanan--0.20-0.05-0.05 0.20 Xanthan gum- − − − − − − − − Locust bean gum − − − − − − − − − Guar gum − − − − − − − − − Chitosan − − − − − − − − Pectin − − − − − − − − − Alginate sorter − − − − -----Human peroxyethyl cellulose--------Carboxoxyvinyl polymer--------Glycerin 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 Urea 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Betaine 0.35 0.35 0.35 0.35 0.35 0.35 0.35 0.35 Succinic acid 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Disodium hydrogen phosphate 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.0 0 Ethanol 4.00 4.00 4.00 4.00 4.00 4.00 4.00 4.00 Purified water Balance Balance Balance Balance Balance Balance Balance Balance Total Balance 100 100 100 100 100 100 100 100

[0040]

[Table 3] Ingredients Example (% by weight) 10 11 12 13 14 15 16 κ-Karachidanan---0.05 0.05 0.05 0.05 ι-Karachidanan 0.05 0.20 0.20 0.20 0.20 0.20 0.20 λ-Karachidanan 0.20------Xanthancam-0.05--- --Locust Bean Cam--0.05----Guar Gum-------Chitosan-------Pectin-------Sorting Alginate-------Human Peroxyethyl Cellulose--- ----Carboxyvinyl polymer disodium hydrogen 1.00 1.00 1.00 1.00 1.00 1.00 1.00 ethanol 4.00 4.00 4.00 4.00 4.00 4.00 4.00 purified water balance Ha Bu lance Ha Bu lance Ha Bu lance Ha Bu lance Ha Bu lance Ha Bu lance a total of 100 100 100 100 100 100 100

[0041]

[Table 4] Component Comparative Example (% by weight) 3 4 5 6 7 8 9 9 10 11 κ-Karachidanan--------0.05 ι-Karachidanan--------0.20 λ-Karachidanan------- --Xanthan camp 0.20--------Locust bean gum-0.20-------Guar gum--0.20------Chitosan---0.20-----Pectin----0.20 ----Sorter alginate------0.20---Human peroxyethyl cellulose------0.20--Carboxoxyvinyl polymer-------0.20-Glycerin 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 Urea 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Betaine 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00-Succinic acid 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Phosphoric acid 1 Disodium hydrogen 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 Ethanol 4.00 4.00 4.00 4.00 4.00 4.00 4.00 4.00 4.00 Purified water Balanced Balanced Balanced Balanced Balanced Balanced Balanced Balanced Balanced Total 100 100 100 100 100 100 100 100 100

[0042]

[Table 5] Example 2 3 4 5 6 7 8 9 Initial pH 4.40 4.40 4.40 4.41 4.40 4.39 4.40 4.40 Moist feeling ○ ○ ○ ○ ○ ○ ○ ○ Smooth feeling ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ Smoothness ○ ○ ○ ○ ○ ◎ ○ ○ Non-stickiness ◎ ◎ ◎ ○ ○ ◎ ○ ○ Smoothing effect ○ ○ ○ ○ ○ ◎ ○ ○ Smoothness persistence ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ Smoothness persistence ○ ○ ○ ○ ○ ◎ ○ ○

[0043]

[Table 6] Example 10 11 12 13 14 15 16 Initial pH 4.41 4.40 4.41 4.36 4.42 4.44 4.47 Moist feeling ○ ○ ○ ○ ◎ ◎ ◎ Smooth feeling ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ Smoothness ○ ○ ○ ○ ◎ ◎ ○ Non-stickiness ○ ○ ○ ◎ ◎ ○ ○ Smoothing effect ○ ○ ○ ◎ ◎ ◎ ◎ Smooth feeling lasting ◎ ◎ ◎ ◎ ◎ ◎ ◎ Smoothness sustainability ○ ○ ○ ○ ◎ ◎ ○

[0044]

[Table 7] Comparative Example 3 4 5 6 7 8 9 10 11 Initial pH 4.40 4.38 4.34 4.40 4.43 4.45 4.44 4.40 4.20 Moist feeling ○ ○ ○ ○ ○ ○ ○ ○ △ Smooth feeling △ △ △ △ △ △ × △ ◎ Smoothness △ △ △ △ △ △ × △ ○ Non-stickiness △ △ △ △ △ △ × △ ◎ Smoothing effect △ △ △ × △ △ △ × △ Smoothness persistence × × × × × × × × × Smoothness persistence × × × × × × × × × As a result, Comparative Examples 3 to 10 containing no carrageenan
Is inferior in smoothness, smoothness, non-greasiness, and smoothing effect, and Comparative Example 11 containing no betaine is inferior in moist feeling and smoothing effect. Feeling, smooth feeling, smoothness,
It can be seen that both the non-stickiness and the smoothing effect are good, and that their persistence is also excellent.

Reference Example 1 In order to examine the pH dependency of the thickening action of carrageenan used in the present invention, pH 4 and pH 7 were adjusted so that l-carrageenan (Soagina MV320, manufactured by Mitsubishi Rayon Co., Ltd.) was a 1% by weight aqueous solution. , PH 9 (70 ° C.), stirred and dissolved, and the viscosity and pH at room temperature were measured. Note that a 5 mM succinate buffer was used for preparing a pH 4 solution, a 5 mM phosphate buffer was used for preparing a pH 7 solution, and a 5 mM borate buffer was used for preparing a pH 9 solution. Also, instead of carrageenan,
Xanthan gum (Neosoft, manufactured by Sanei Chemical Industry Co., Ltd.) and carboxyvinyl polymer (Carbopol, manufactured by BFG Inc.), which are generally used as water-soluble thickeners, are used. And were measured. The results are shown in FIG. Numerical values in the figure are measured values of pH.

From FIG. 1, the aqueous solution of ι-carrageenan is
Compared to other aqueous solutions of thickeners, the preferred pH for the skin is 4 to
6, especially in the acidic range of pH 4-5, the viscosity becomes high. Therefore, it can be seen that the cosmetic of the present invention using carrageenan can increase the viscosity to a desired viscosity in a pH range preferable for the skin and achieve a good feeling in use.

Reference Example 2 In order to compare the thickening effect and feeling of use of carrageenan used in the present invention with various other thickeners, the evaluation compositions shown in Table 8 were used with the various thickeners shown in Table 9. And their viscosities were measured. The feeling of use was evaluated on a four-point scale in the same manner as described above by a specialized panelist. In this case, the feeling of use was a comprehensive evaluation of (i) moist feeling, (ii) smooth feeling, (iii) smoothness, (iv) non-stickiness, and (v) smoothing effect. Further, the viscosity of the prepared composition was measured (temperature: 25 ° C., 12 rpm, 60 seconds). Table 9 shows these results.
Shown in

[0048]

Table 8 Composition for evaluation (% by weight) Succinic acid 1.55 Arginine 2.00 95% ethanol 5.00 Thickener 0.40 Purified water Balance pH 4.0

[0049]

[Table 9] Thickener Viscosity (cps) Usability Carrageenan (κ) * 1 10,000 or more ○ ○ (ι) * 2 2900 ○ 〃 (ι) * 3 4420 ○ 〃 (ι) * 4 6890 ○ 〃 (ι) * 5 5250 ○ Xanthan gum * 6 1300 △ 〃 * 7 1300 △ 〃 * 8 1100 △ Locust bean gum * 9 50 △ 〃 * 10 20 △ 〃 * 11 30 △ 〃 * 12 90 △ Guar gum * 13 50 △ 〃 * 14 40 △ Chitosan * 15 10 △ pectin * 16 50 △ sodium alginate * 17 20 △ hydroxyethylcellulose * 18 60 × hydroxypropylcellulose * 19 30 × carboxyvinyl polymer * 20 30 △ acrylic acid resin * 21 5 △ (Note) * 1 Soagina MV101, manufactured by Mitsubishi Rayon Co., Ltd. * 2 Soagina MV220, manufactured by Mitsubishi Rayon Co., Ltd. * 3 Soagina MV201, manufactured by Mitsubishi Rayon Co., Ltd. * 4 Soagina MV320, manufactured by Mitsubishi Rayon Co., Ltd. * 5 Soagina MV330, manufactured by Mitsubishi Rayon Co., Ltd. * 6 KELTOROL, manufactured by Dainippon Pharmaceutical Co., Ltd. * 7 Neosoft XK, manufactured by Sanei Chemical Industry Co., Ltd. * 8 Echogum T, manufactured by Dainippon Pharmaceutical Co., Ltd. * 9 Genugum RL-200J, Copenhagen Pectin Factory Co. * 10 Meyprodyn 200, May Hall Co., Ltd. * 11 Meypro-LBG, May Hall Co., Ltd. * 12 Soarcast A200, Mitsubishi Rayon Co., Ltd. * 13 Meyprogat 120, May Hall ( * 14 Jagur C-13S, manufactured by Rhone Plan Co., Ltd. * 15 SK-10, Chemical Co., Ltd. * 16 Genupectin typeVIS, Copenhagen pectin factory Co., Ltd. * 17 Kimitsu Co., Ltd. * 18 850K, Daicel Chemical Industries Co., Ltd., * 19 NISSOH (Ltd.) * 20 Carbopol 941, B. F. G. FIG. * 21 PEMULEN TR-2, BF GOODRIC
The results in Table 9 manufactured by Company H show that carrageenan exerts an excellent thickening effect in the composition for evaluation. In particular, ι
-It is understood that the thickening effect of carrageenan is excellent.

[0050]

According to the cosmetic of the present invention, a moisturizing effect and
Moist feeling, smooth feeling, or smoothness can be improved together, and their sustainability can be improved.

[Brief description of the drawings]

FIG. 1 is a diagram showing the relationship between pH and viscosity of each thickener.

Continuation of front page (56) References JP-A-59-182898 (JP, A) JP-A-6-247826 (JP, A) JP-A-6-16529 (JP, A) JP-A-5-339141 (JP) JP-A-5-194186 (JP, A) JP-A-5-163129 (JP, A) JP-A-5-51311 (JP, A) JP-A-1-275511 (JP, A) (58) Field surveyed (Int. Cl. ⁷ , DB name) A61K ^7/ 00-7/50

Claims (5)

(57) [Claims] 1. Glycine betaine 0.01 to 10% by weight
And 0.01 to 10% by weight of carrageenan, pH
Is 4.0 to 6.0. 2. The cosmetic according to claim 1, which contains an acidic polysaccharide derived from a callus culture of a plant belonging to the genus Polyanthes. 3. The cosmetic according to claim 1, which comprises a carboxylic acid, an amino acid, and urea. 4. The cosmetic according to claim 3, which contains a basic amino acid as the amino acid. 5. The cosmetic according to claim 4, wherein the content ratio of the basic amino acid to glycine betaine is 1: 0.01 to 99 by weight.