JP3502622B2 - Simple method for determination of volatile organic compounds in gases - Google Patents

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a method for quantifying the amount of volatile organic compounds in a gas. More specifically, the present invention identifies at least one or more volatile organic compounds present in a gas such as indoor air simply and accurately by using a retention index obtained based on the detection position of saturated hydrocarbon. The present invention relates to a simple method for quantifying the amount of volatile organic compounds in a gas that can be quantified.

[0002]

2. Description of the Related Art Interest in indoor air pollution has been increasing in recent years. The amount of volatile organic compounds in the indoor air is convenient for understanding the degree of pollution in the room,
Therefore, accurate evaluation and measurement of volatile organic compounds in indoor air have become extremely important. As a method for analyzing volatile organic compounds in indoor air, a certain amount of indoor air is sucked into the adsorbent and the contained volatile organic compounds are adsorbed to the adsorbent, and then, for example, by heat desorption or solvent desorption. A method is known in which the adsorbed volatile organic compound is desorbed and the desorbed product is measured by gas chromatography or gas chromatography / mass spectrometry. In this method, for each detected substance after measurement, the detected substance is identified using the mass spectrum analysis and the measurement result of the standard substance, and the quantification is individually performed using the measurement result of the standard substance. . Alternatively, a batch conversion quantitative method is also known in which the representative substances are quantified and the quantified values for each detected substance are collectively converted from the results.

[0003]

However, in the above method, after each measurement, the detected substance is identified using the mass spectrum and the measurement result of the standard substance, and the measurement result of the standard substance is determined. When performing quantification individually, it is sometimes necessary to perform identification by mass spectrum analysis or confirmation with a standard substance for each hundreds of detected substances, and further quantification using the measurement results with the standard substance is necessary. Therefore, it takes a lot of time. On the other hand, the method of batch conversion quantification using the quantified value of the representative substance instead of individual quantification makes it difficult to grasp the exact concentration because the detection intensity differs for each compound even at the same concentration. There was a problem. Therefore, there has been a strong demand for a practical analytical method for obtaining the amount of volatile organic compounds in indoor air, which is free from these problems.

The present invention solves the above-mentioned problems of the prior art, and easily and accurately eliminates the need to individually identify and quantify volatile organic compounds present in hundreds of kinds of indoor air. The present inventor, whose purpose is to provide an analytical method capable of qualitatively and quantitatively determining, the relative intensity ratio and the retention index of the detection intensity with respect to the reference substance obtained for various volatile organic compounds, as a result of extensive studies. The present invention has been completed by finding that the above object can be achieved by using.

[0005]

That is, the present invention uses the detection intensity ratio with respect to a reference substance and the retention index for one or more volatile organic compounds obtained by the following first to third steps. And a simple quantification method for the amount of volatile organic compounds in a gas, which comprises the following 4th to 9th steps. [First Step] A solution containing a reference substance and one or more kinds of volatile organic compounds is brought into contact with an adsorbent, and the reference substance and the volatile organic compound are adsorbed on the adsorbent, and then the reference substance and the volatile organic compound are adsorbed. A step of desorbing the compound from the adsorbent, performing gas chromatograph-mass spectrometry or gas chromatographic measurement on the obtained desorbed product, and obtaining a detection intensity ratio with respect to a reference substance and a retention time for each volatile organic compound, [second Process] A solution containing two or more kinds of linear saturated hydrocarbons is contacted with an adsorbent, the linear saturated hydrocarbons are adsorbed on the adsorbent, and then the linear saturated hydrocarbons are desorbed from the adsorbent to obtain Gas chromatograph-mass spectrometry or gas chromatographic measurement is performed on the desorbed product thus obtained to obtain a retention time for each linear saturated hydrocarbon, [third step] A step of obtaining a retention index for each volatile organic compound from the retention time for each volatile organic compound determined in the above step and the retention time for each linear saturated hydrocarbon determined in the second step, [fourth step] After contacting a certain amount of the gas to be measured with the adsorbent to adsorb the volatile organic compound in the gas to the adsorbent, the adsorbed volatile organic compound is desorbed, and the desorbed product obtained is gas chromatograph- A step of performing mass spectrometry or gas chromatographic measurement to determine the detection intensity and retention time for each detected substance, [Fifth step] A solution containing one or more kinds of linear saturated hydrocarbons is contacted with an adsorbent, After the chain saturated hydrocarbon is adsorbed on the adsorbent, the linear saturated hydrocarbon is desorbed from the adsorbent, and the desorbed product obtained is subjected to gas chromatography-mass spectrometry or gas chromatography. A step of performing a mattograph measurement to obtain a retention time for each straight chain saturated hydrocarbon, [Sixth step] A retention time for each detected substance obtained in the fourth step, and each straight chain saturation obtained in the fifth step A step of obtaining a retention index for each detected substance from the retention time for hydrocarbons, [seventh step] a retention index for each volatile organic compound determined in the third step, and each detected substance determined in the sixth step Step of identifying each detected substance from the retention index, [Eighth step] A solution containing a plurality of concentration levels of the reference substance was brought into contact with the adsorbent, and the reference substance was adsorbed on the adsorbent and then adsorbed. Desorb the reference substance, perform gas chromatograph-mass spectrometry or gas chromatographic measurement on the obtained desorbed substance, and obtain the detection intensity at each concentration level to obtain the concentration of each reference substance. The step of obtaining the relationship between the level and the detection intensity, [9th step] the detection intensity ratio of each volatile organic compound obtained in the 1st step to the reference substance, and the detected substance obtained in the 4th step From the detection intensity, the identification result of each detected substance obtained in the seventh step, and the relationship between each concentration level of the reference substance obtained in the eighth step and the detection intensity, each volatile organic compound in the gas to be measured The process of determining the concentration.

[0006]

BEST MODE FOR CARRYING OUT THE INVENTION As a gas containing an amount of a volatile organic compound to be measured by the simple quantification method of the present invention,
Room air is an example. As this indoor air, general detached houses and condominiums, offices, schools and hospitals, movie theaters,
Examples include public facilities such as halls and department stores, and air inside vehicles such as trains and automobiles.

The amount of volatile organic compounds to be measured by the simple quantitative method of the present invention is not particularly limited,
Usually, it is an organic compound that has a boiling point of up to 400 ° C. and exists in a gaseous state or a particulate state in a gas such as indoor air.

The adsorbent used in the first step, the second step, the fourth step, the fifth step, the eighth step, etc. is not particularly limited, but it is a carbon molecular sieve-based adsorbent or a graphite carbon black-based adsorbent. Adsorbent, silica gel, 2,6-diphenylene oxide adsorbent, styrene /
Examples thereof include a divinylbenzene-based adsorbent, an octadecyl group chemically bonded adsorbent and a disc-shaped adsorbent carrying the same, quartz wool and its disc-shaped adsorbent, and activated carbon.

In the first step of the present invention, a solution containing a reference substance and one or more kinds of volatile organic compounds is contacted with an adsorbent, and the reference substance and the volatile organic compound are adsorbed on the adsorbent, The reference substance and volatile organic compound are desorbed from the adsorbent, and the obtained desorbed product is subjected to gas chromatograph-mass spectrometry or gas chromatograph measurement, and the detection intensity ratio and retention time of the reference substance for each volatile organic compound and the retention time are determined. This is the process of seeking. A solution containing a reference substance and one or more volatile organic compounds is
A solution which simultaneously contains a predetermined amount of a reference substance and one or more kinds of volatile organic compounds in a solvent, and the solvent used here is methanol, a methanol / water mixed liquid, carbon disulfide, carbon disulfide. / Alcohol mixed liquid is illustrated, but it is not limited to this. Toluene or the like is preferable as the reference substance. The one or more kinds of volatile organic compounds are volatile organic compounds assumed to be contained in the gas to be measured, and may contain several hundred kinds of volatile organic compounds. The effect of the present invention becomes more remarkable as the number of types of volatile organic compounds to be measured increases. The concentration of the reference substance and each volatile organic compound in the solution containing the reference substance and one or more volatile organic compounds is preferably 10 to 500 μg / ml. If the concentration is too low, there is a large error in the detection peak area measurement, and the accuracy of the detection intensity ratio may be lost. On the other hand, if the concentration is excessive, the accuracy of the ratio of detected intensities may be lost in the same manner as the allowable amount of the analyzer is exceeded.

The contact between the adsorbent and the solution containing the reference substance and one or more kinds of volatile organic compounds may be carried out, for example, by passing the solution through an adsorbent tube filled with the adsorbent, or adsorbent filled with the adsorbent. Examples include a method of adding the solution to a tube or a cartridge, and the reference material and the volatile organic compound are adsorbed by the adsorbent by such a method. The reference substance and the volatile organic compounds adsorbed on the adsorbent are then desorbed from the adsorbent. Examples of the desorption method include a heating method (heat desorption method) and a solvent desorption method. In the case of the heat desorption method, the heating temperature is not particularly limited, but usually 150 to 300 ° C., especially 25
About 0 ° C. is used. In the case of desorption with a solvent, the solvent used for the desorption is not particularly limited, but carbon disulfide, carbon disulfide containing alcohol, acetone, dichloromethane and the like are preferable. The desorbed product thus obtained is measured by gas chromatography or gas chromatography / mass spectrometry, and the detection intensity ratio of each volatile organic compound to the reference substance and the retention time are obtained. Examples of methods for obtaining the detection intensity ratio with the reference substance include the ratio of the peak area of the reference substance to the peak area of the volatile organic compound and the concentration of the reference substance and the volatile organic compound in the solution. However, it is not limited to these. Ordinary conditions are adopted as the measurement conditions in the gas chromatograph method or the gas chromatograph / mass spectrometry method. The obtained detection intensity ratio does not change as long as the analyzer and the analytical column are the same, and once obtained, it is not necessary to obtain it each time after measurement, and it can be continuously used. The variation range of the intensity ratio is ± 20%.

In the second step of the present invention, a solution containing two or more kinds of linear saturated hydrocarbons is contacted with an adsorbent, the linear saturated hydrocarbons are adsorbed on the adsorbent, and then the linear saturated hydrocarbon is adsorbed. In this step, hydrogen is desorbed from the adsorbent, and the desorbed material obtained is subjected to gas chromatograph-mass spectrometry or gas chromatograph measurement to determine the retention time for each linear saturated hydrocarbon. The contact between the solution containing two or more kinds of linear saturated hydrocarbons and the adsorbent can be carried out, for example, by passing the solution through an adsorbent tube filled with the adsorbent, or by adsorbing the adsorbent with an adsorbent tube or cartridge. Examples include a method of adding a solution, and the linear saturated hydrocarbon is adsorbed by the adsorbent by such a method. Examples of the straight chain saturated hydrocarbon include hexane, heptane, octane, nonane, decane, undecane, dodecane, tridecane, tetradecane, pentadecane, and hexadecane. A solution containing a linear saturated hydrocarbon is a solution containing two or more kinds of such linear saturated hydrocarbons in a solvent at the same time. Examples of the solvent used here include methanol, acetone and the like. However, it is not limited to this. The concentration of the linear saturated hydrocarbon in the solution is 10 to 500 μg / m
1 is preferred. If the concentration is too low, the error in the detection position may be large, and the accuracy of the retention index required in the third step may be lost. Index accuracy may be lost. The linear saturated hydrocarbon adsorbed on the adsorbent is then desorbed from the adsorbent, and the desorbed product is measured by gas chromatography or gas chromatography / mass spectrometry, and the retention time for each linear saturated hydrocarbon is determined. Desired. The desorption method and conditions, and the conditions for gas chromatography or gas chromatography / mass spectrometry are the same as those in the first step.

The third step of the present invention is to determine each volatile organic compound from the retention time for each volatile organic compound determined in the first step and the retention time for each linear saturated hydrocarbon determined in the second step. Is a step of obtaining a retention index for. The retention index is a relative information of retention time, and is exemplified by PTRI obtained by using the following formula. _{PTRI = 100 ((T A -T} Z) / (T Z + 1 -T Z)) + 100
Z (where T _A is the retention time of the target compound, T _Z is the retention time of the straight chain saturated hydrocarbon eluted immediately before the target compound, T _{Z
Z + 1} represents the retention time of the linear saturated hydrocarbon that elutes immediately after the target compound, and Z represents the carbon number of the linear saturated hydrocarbon that elutes immediately before the target compound. ) The obtained retention index does not change even if the analytical device is different if the analytical column is of the same system. Once obtained, it is not necessary to obtain it each time after measurement, and it can be used continuously. . The range of fluctuation of the retention index is ± 1.
5%. As described above, the first to third steps do not have to be repeated for each measurement target, and once measured, the detection intensity ratio and the retention index obtained in each subsequent measurement can be used.

In the fourth step of the present invention, a fixed amount of the gas to be measured is brought into contact with the adsorbent to adsorb the volatile organic compound in the gas to the adsorbent, and then the adsorbed volatile organic compound is desorbed. In this step, the obtained desorbed substance is subjected to gas chromatograph-mass spectrometry or gas chromatograph measurement to obtain the detection intensity and retention time for each detected substance. As a method of bringing a fixed amount of the gas to be measured into contact with the adsorbent, a method of sucking a fixed amount of the gas to be measured into a column filled with the adsorbent and passing the gas through the column is exemplified. In this way, the volatile organic compound in the gas is adsorbed by the adsorbent. The amount of suction is not particularly limited, but suction of 1 to 29000 L is usually preferable at a rate of 0.05 to 20 L / min.

The volatile organic compounds in the gas adsorbed on the adsorbent are then desorbed from the adsorbent, and the desorbed substances are measured by gas chromatography or gas chromatograph / mass spectrometry, and each detected substance, that is, gas. For the volatile organic compounds contained therein, the detection intensity and retention time are required.

In the fifth step of the present invention, a solution containing one or more kinds of linear saturated hydrocarbons is contacted with an adsorbent, the linear saturated hydrocarbons are adsorbed to the adsorbent, and then the linear saturated hydrocarbons are adsorbed. In this step, hydrogen is desorbed from the adsorbent, and the desorbed material obtained is subjected to gas chromatograph-mass spectrometry or gas chromatograph measurement to determine the retention time for each linear saturated hydrocarbon. For linear saturated hydrocarbon solutions (for example, type of linear saturated hydrocarbon, solvent and concentration, etc.), contact method with adsorbent, desorption method and conditions, gas chromatography or gas chromatography / mass spectrometry The conditions are the same as in the case of the second step. However, this step is performed for each measurement of the gas to be measured.

In the sixth step of the present invention, the retention time for each detected substance is calculated from the retention time for each detected substance obtained in the fourth step and the retention time for each linear saturated hydrocarbon obtained in the fifth step. This is a process of obtaining an index. The method for obtaining the retention index is the same as in the third step, and PTRI is a representative example of the retention index. The seventh step of the present invention is the third step.
This is a step of identifying each detected substance from the retention index for each volatile organic compound determined in the step and the retention index for each detected substance determined in the sixth step. The detection compound is identified by comparing the retention index obtained in the sixth step with the retention index obtained in the third step and searching for a component having a matching numerical value. That is, a detected substance having a retention index equal to or close to the retention index of a certain component A obtained in the third step is identified as the component A. In this way, the identification of a large number of detected substances can be easily performed only by comparing with the retention index obtained in the third step.

Each of the detected substances identified as described above is quantified by the steps 8 to 9 described below. The eighth step of the present invention was obtained by contacting a solution containing a plurality of concentration levels of a reference substance with an adsorbent, causing the adsorbent to adsorb the reference substance, and then desorbing the adsorbed reference substance. This is a step of obtaining the relationship between each concentration level of the reference substance and the detection intensity by performing gas chromatograph-mass spectrometry or gas chromatograph measurement on the desorbed substance and obtaining the detection intensity at each concentration level. As the solution of the reference substance, a methanol solution containing the reference substance such as toluene, a carbon disulfide solution containing the reference substance,
A carbon disulfide / alcohol mixed solution containing a reference substance may be mentioned, but the present invention is not limited thereto. Multiple concentration levels of the reference substance are selected, but 1
It is preferably 3 points or more within the widest possible range of 0 to 500 μg / ml. The method of contact with the adsorbent, the method and conditions of desorption, and the conditions of gas chromatography or gas chromatography / mass spectrometry are the same as in the case of the first step. In this way, the relationship between each concentration level of the reference substance and the detected intensity is obtained, and this relationship is usually represented by a calibration curve with one as the vertical axis and the other as the horizontal axis.

In the ninth step of the present invention, the detection intensity ratio of each volatile organic compound obtained in the first step to the reference substance, the detection intensity of each detected substance obtained in the fourth step,
The concentration of each volatile organic compound in the gas to be measured is obtained from the identification result of each detected substance obtained in the seventh step and the relationship between each concentration level of the reference substance obtained in the eighth step and the detected intensity. It is a process. In this step, for example, the detection intensity of each detected substance obtained in the fourth step (the volatile organic compound name identified in the seventh step is known) is
The detection intensity ratio for each volatile organic compound obtained in the step is used to convert to the detection intensity of the reference substance, and the converted value and each concentration level of the reference substance obtained in the eighth step and the detection intensity Each concentration is obtained using a relationship (for example, a calibration curve). In addition, the relationship between each concentration level of the reference substance obtained in the eighth step and the detection intensity (for example, a calibration curve), using the detection intensity ratio for each volatile organic compound obtained in the first step, The relationship (for example, a calibration curve) between each concentration level of each volatile organic compound and the detection intensity was obtained, and this relationship and each detected substance obtained in the fourth step (the volatile organic compound name identified in the seventh step was identified) The detection intensity for each of the detected substances obtained in the fourth step (the volatile organic compound name is identified in the seventh step) and From the relationship between each concentration level of the reference substance obtained in the 8th step and the detection intensity (for example, a calibration curve), the reference substance conversion concentration of each component is obtained, and the detection intensity of the reference substance and each component obtained in the 1st step There is also a method of multiplying the ratio to obtain each concentration, etc. That. By doing so, it is possible to obtain a value with an accuracy almost equivalent to the concentration quantified by the calibration curve adjusted with the reagent standard product.

The greatest feature of the present invention is that the qualitative determination of hundreds of volatile organic compounds in a gas such as indoor air without performing individual mass spectrum analysis and the like, and the detection with reference substances By using the intensity ratio, it is possible to obtain a quantitative value with the same accuracy as the quantitative determination using a reagent standard, and to easily and accurately determine the amount of volatile organic compounds.

The present invention will be described below with reference to examples.
The examples do not limit the method according to the invention.

Example (1) First step Methanol / water solution (SU containing 100 μg / ml each of toluene and the volatile organic compounds shown in Table 1)
PELCO mixed standard solution for indoor air analysis) is adsorbent T
After passing through enaxGR (adsorbent by mixing 2,6-diphenylene oxide and activated carbon, manufactured by GL Sciences Inc.) to adsorb toluene and volatile organic compounds to the adsorbent, using a heat desorption device CP2020, Desorption was performed by the thermal desorption method, and the obtained desorbed material was subjected to gas chromatography-mass spectrometry to determine the detection intensity ratio with toluene and the retention time for each volatile organic compound.
The gas chromatograph-mass spectrometry was performed using QP-5000 (manufactured by Shimadzu Corporation) under the following conditions. Column: DB-5 (0.25 id x 60 m x 0.2
5 μm film (J & W) Temperature: 40 ° C. (5 minutes) Temperature rise at −10 ° C./min −250 ° C.
(15 minutes) Carrier gas: Helium (1 ml / min)

(2) Second and third steps Adsorbent Tenax GR was passed through a methanol solution containing hexane, heptane, octane, nonane, decane, undecane, dodecane, tridecane, tetradecane, pentadecane and hexadecane, respectively, at 100 μg / ml. The straight chain saturated hydrocarbon of was adsorbed, desorption and gas chromatograph-mass spectrometry were similarly performed, and the retention time for each straight chain saturated hydrocarbon was determined. The retention index (PTRI) for each volatile organic compound was determined from this retention time and (1) the retention time for each volatile organic compound obtained in the first step. Table 1 shows the detection intensity ratios with toluene and the retention index (PTRI) thus obtained.

[0023]

[Table 1]

(3) Fourth step The air in the living room of the newly built condominium is treated with the adsorbent Tena.
After suctioning and absorbing 3 L to xGR at a rate of 100 ml / min, the thermal desorption device CP2020 was used to desorb by desorption, and the resulting desorbed product was subjected to gas chromatography-mass spectrometry. The detection intensity and retention time for each detected substance were determined. The conditions for gas chromatography-mass spectrometry are the same as in (1) Step 1.

(4) Fifth Step, Sixth Step, Seventh Step Adsorbent Tenax GR contains hexane, heptane, octane, nonane, decane, undecane, dodecane, tridecane, tetradecane, pentadecane and hexadecane at 100 μg / ml each. These linear saturated hydrocarbons were adsorbed through a methanol solution, and desorption and gas chromatograph-mass spectrometry were performed in the same manner to determine the retention time for each linear saturated hydrocarbon. The retention index (PTRI) for each detected substance was determined from this retention time and the retention time for each detected substance obtained in the (3) fourth step. The results are shown in Table 2.

By comparing the retention index of the substance detected in the room air thus obtained with the retention index obtained in the third step (2), the identification (qualitative) of each detected substance is obtained. I went. The results are shown in Table 2. In addition, the method of identifying the compound from the mass spectrum as in the conventional method was also performed, and the results of comparing the two are also shown in Table 2. As is clear from Table 2, the method of the present invention gave the same qualitative results as the conventional method.

(4) Steps 8 and 9 Toluene 10 μg / ml, 50 μg / ml, 100 μg
/ Ml, 200μg / ml methanol solution to make,
After adsorbing to the adsorbent Tenax GR, the detection intensity of toluene at each concentration was obtained in the same manner as in (1) Step 1. A calibration curve was created from the detection intensity and the concentration thus obtained. For each substance qualified in the 7th step of (4), the quantitative conversion to toluene was carried out from this calibration curve. Then, the quantitative value for each substance was obtained by multiplying the detection intensity ratio obtained in (1), and the total amount of volatile organic compounds was obtained by summing all the quantitative values. The results are shown in Table 2. Table 2 also shows the comparison results obtained by the conventional method of quantifying the qualitative compounds using a calibration curve with reagents.
It has been found that the method of the present invention can obtain almost the same results as the conventional method.

[Table 2]

[0028]

The simple quantification method of the total amount of volatile organic compounds in the gas of the present invention enables the volatile organic compounds present in the indoor air, which sometimes reaches several hundred kinds, to be individually identified and quantified. , Which can be easily and accurately qualitatively and quantitatively determined.

─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Ayumi Hasegawa 1 9 Kita-sode, Sodegaura-shi, Chiba Sumika Chemical Analysis Service Co., Ltd. (56) References JP2003-139755 (JP, A) JP8- 313510 (JP, A) JP-A-5-72191 (JP, A) JP-A-5-93719 (JP, A) (58) Fields investigated (Int.Cl. ⁷ , DB name) G01N 30/00-30 / 96

Claims (7)

(57) [Claims] 1. Using the detection intensity ratio and retention index of one or more kinds of volatile organic compounds with a reference substance, which are obtained by the following first to third steps, and having the following fourth to ninth steps. A simple method for quantifying the amount of a volatile organic compound in a gas, which is characterized in that [First Step] A solution containing a reference substance and one or more kinds of volatile organic compounds is brought into contact with an adsorbent, and the reference substance and the volatile substance are volatilized. After adsorbing the volatile organic compound to the adsorbent, desorbing the reference substance and the volatile organic compound from the adsorbent, and subjecting the obtained desorbed material to gas chromatograph-mass spectrometry or gas chromatograph measurement, for each volatile organic compound Of the detection intensity ratio with respect to the reference substance and the retention time, [Second step] A solution containing two or more kinds of linear saturated hydrocarbons is brought into contact with an adsorbent to obtain the linear saturated hydrocarbons. Was adsorbed on the adsorbent, the linear saturated hydrocarbon was desorbed from the adsorbent, the obtained desorbed product was subjected to gas chromatograph-mass spectrometry or gas chromatographic measurement, and the retention time for each linear saturated hydrocarbon was determined. Step to be determined, [Third step] From the retention time for each volatile organic compound determined in the first step and the retention time for each linear saturated hydrocarbon determined in the second step, the retention for each volatile organic compound is determined. Step of obtaining index, [Fourth step] After contacting a certain amount of the gas to be measured with the adsorbent to adsorb the volatile organic compound in the gas to the adsorbent, desorb the adsorbed volatile organic compound , A step of performing gas chromatograph-mass spectrometry or gas chromatograph measurement on the obtained desorbed product to obtain the detection intensity and retention time for each detected product, Step] A solution containing one or more kinds of linear saturated hydrocarbons is contacted with an adsorbent, the linear saturated hydrocarbons are adsorbed on the adsorbent, and then the linear saturated hydrocarbons are desorbed from the adsorbent to obtain Gas chromatograph-mass spectrometry or gas chromatographic measurement is performed on the desorbed product thus obtained to obtain a retention time for each linear saturated hydrocarbon, [Sixth step] Retention time for each detected substance obtained in the fourth step. And a step of obtaining a retention index for each detected substance from the retention time for each linear saturated hydrocarbon obtained in the fifth step, [Seventh step] Retention index for each volatile organic compound obtained in the third step And a step of identifying each detected substance from the retention index for each detected substance obtained in the sixth step, [8th step] contacting a solution containing a plurality of concentration-level reference substances with an adsorbent, After adsorbing the quasi-substance to the adsorbent, desorb the adsorbed reference substance, perform gas chromatograph-mass spectrometry or gas chromatograph measurement on the obtained desorbed product, by determining the detection intensity for each concentration level, A step of obtaining the relationship between each concentration level of the reference substance and the detected intensity, [9th step] the detection intensity ratio of the reference substance for each volatile organic compound obtained in the 1st step, obtained in the 4th step From the detection intensity of each detected substance, the identification result of each detected substance obtained in the seventh step, and the relationship between each concentration level of the reference substance obtained in the eighth step and the detected intensity, The step of obtaining the concentration of each volatile organic compound. 2. The simple quantitative method according to claim 1, wherein the volatile organic compound has a boiling point of 400 ° C. or less and is present in a gas in a gaseous or particulate form. 3. The simple quantitative method according to claim 1, wherein the gas is room air. 4. The retention index PT obtained by the following formula:
The simplified quantification method according to claim 1, wherein the method is RI. _{PTRI = 100 ((T A -T} Z) / (T Z + 1 -T Z)) + 100
Z (where T _A is the retention time of the target compound, T _Z is the retention time of the straight chain saturated hydrocarbon eluted immediately before the target compound, T _{Z
Z + 1} represents the retention time of the linear saturated hydrocarbon that elutes immediately after the target compound, and Z represents the carbon number of the linear saturated hydrocarbon that elutes immediately before the target compound. ) 5. The simple quantitative method according to claim 1, wherein the desorption from the adsorbent is a desorption by heating or a solvent. 6. The simple quantitative determination according to claim 1, wherein the linear saturated hydrocarbon is hexane, heptane, octane, nonane, decane, undecane, dodecane, tridecane, tetradecane, pentadecane and hexadecane. Law. 7. The simple quantitative method according to claim 1, wherein the relationship between each concentration level of the reference substance and the detected intensity is a calibration curve.