JP3427393B2 - Hydraulic pressure monitoring device - Google Patents

Description

Detailed Description of the Invention

[0001]

The present invention relates, for example by utilizing the centrifugal force and the force flow relates liquid pressure monitoring device of the apparatus for separating cells by size.

[0002]

2. Description of the Related Art FIG. 2 shows a conventional hydraulic pressure monitoring device. An apparatus having an eluting rotor has a portion for feeding the liquid in the pipe. The liquid is fed to the system main body 8 by the liquid feeding pump 5 sucking up the liquid contained in the beaker 7 and the piping 9. If the pressure of liquid transfer is high, the connection of the pipe may be disconnected. Therefore, the conventional technique is to install a pressure gauge 6 in the middle of the pipe 9 to measure the pressure of the liquid flowing in the pipe, and visually check whether the value is always within a normal pressure range. The pump 5 was stopped manually.

[0003]

[Problems to be Solved by the Invention] Eltriator rotor
The device with has to sterilize all tubing to handle cells. Sterilization is generally performed in an autoclave (put in a device that creates conditions of 1.2 atm, 121 ° C., 20 minutes), but in the conventional one, the pressure gauge 6 is connected to the pipe 9 so that the pressure gauge is Every six had to be autoclaved. Since the pressure gauge 6 is made of metal, it rusts and breaks down when applied to an autoclave, so that sterilization by the autoclave is practically impossible.

In addition to this, there have been troublesome operations such as the pressure gauge 6 must be constantly monitored and the liquid feed pump 5 must be manually stopped when an abnormality occurs.

The object of the present invention is to completely separate the pipe part and the pressure measuring part in order to enable autoclave sterilization, and to automatically monitor the pressure of the liquid feed and to automatically feed the liquid when an abnormality occurs. It is to stop.

[0006]

[Means for Solving the Problems] The above object is to provide a bottle in the middle of a pipe to form a liquid reservoir, and to make a liquid phase and a gas phase in the bottle. It can be achieved by measuring the capacitance of the liquid phase from the outside of the bottle by using a capacitance sensor without contact with the liquid phase by utilizing the change with pressure change. This can also be achieved by using an electrostatic capacity switch as an electrostatic capacity sensor and stopping the pumping of liquid when an abnormal pressure is reached.

[0007]

The operation is shown in FIG. Prepare the liquid in the beaker 7 and the bottle 1 in advance. The liquid prepared in the beaker 7 is once introduced into the bottle 1 from the introduction pipe 2 by the liquid feeding pump 5. Since the bottle 1 is sealed, the same amount of liquid as the introduced liquid flows through the discharge pipe 3 to the system main body. When the pressure of the flowing liquid increases, the amount of the liquid stored in the bottle 1 increases and the capacitance of the liquid stored in the bottle 1 changes.
This change amount can be sensed in a non-contact manner with the liquid by the capacitance switch 4 on the outside of the bottle, and when the abnormal pressure is reached, the liquid feed pump 5 can be turned off to stop the liquid feed.

[0008]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS FIG. 1 shows the structure of the present invention. An introduction pipe 2 and a discharge pipe 3 are connected to the bottle 1 to the bottle 1. The pipe 2 reaches the upper part of the bottle 1, and the pipe 3 reaches the bottom of the bottle 1. The other end of the introduction pipe 2 is connected to the beaker 7 via the liquid feed pump 5, and the other end of the discharge pipe 3 is connected to the system body 8. Make all these connections in a sealed manner. Further, a capacitance switch 4 is provided near the bottle 1. This switch is connected to the liquid feed pump 5.

[0009]

According to the present invention, the pipe section and the pressure measuring device can be completely independent, and autoclave sterilization is possible. In addition, it automatically monitors the fluid pressure and automatically stops liquid delivery in the event of an abnormality.

[Brief description of drawings]

FIG. 1 is a pressure monitoring device according to the present invention.

FIG. 2 is a conventional pressure monitoring device.

[Explanation of symbols]

1 is a bottle, 2 is an introduction pipe, 3 is a discharge pipe, 4 is a capacitance switch, 5 is a liquid feed pump, 6 is a pressure gauge, 7 is a beaker, 8 is a system body, and 9 is a pipe.

Front page continuation (58) Fields surveyed (Int.Cl. ⁷ , DB name) G01F 23/26 G01L 9/12 B04B 11/02 B04B 15/00

Claims (2)

(57) [Claims] 1. A beaker containing a liquid and a liquid feeding pump for the liquid.
Monitoring the piping that flows according to the operation of the pump and the pressure in the piping
And a means for adjusting the pressure of the beaker.
Between the cell separation device and the cell separation device, depending on the pressure in the pipe.
Provide a resin bottle for the liquid reservoir in which the amount of phase changes
The pipes for injecting liquid and the pipes for
Connect to the top of the resin bottle, and connect the injection side pipe to the liquid
Arranged so as not to contact the phase, and the pipe on the discharge side is
The amount of liquid phase in the resin bottle that extends to the bottom of the liquid phase
The electrostatic capacity sensor that can detect
It is provided on the outside of the resin bottle and can be detected by the capacitance sensor.
The liquid pressure in the pipe can be detected by the change in the amount of the liquid phase discharged.
A hydraulic pressure monitoring device characterized in that it is configured to output. Wherein said using the electrostatic capacity switch as an electrostatic capacitance sensor, a liquid pressure monitoring device according to claim 1, wherein to allow control the liquid feed pump in the switch.