JP3421072B2 - Dental filling composition - Google Patents

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a dental filling composition, and more specifically, it has a high filling amount of an inorganic filler, and the surface smoothness, gloss and transparency of the cured product, and the aesthetics and mechanical properties. TECHNICAL FIELD The present invention relates to a dental filling composition having excellent mechanical strength and durability, and also having excellent radiopacity.

[0002]

2. Description of the Related Art In recent years, a dental filling composition comprising a polymerizable monomer and an inorganic filler has been widely used for repairing various tooth defects. Such a dental filling composition is composed of an acrylic monomer and an inorganic filler such as silica or various glass powders, and the performance of these filling compositions depends on the composition, shape, particle size, and particle size distribution of the inorganic filler. Also, various inorganic fillers have been conventionally proposed because they are greatly affected by the filling amount. Initially, as the inorganic filler,
A powder having a particle size of 5 to 100 μm was used, and no problem was found in mechanical strength, but due to the presence of large particles,
A smooth surface was not obtained and dissatisfaction remained in terms of aesthetics.
On the other hand, in order to obtain a smooth surface, the particle size is 0.01 to 0.0
The use of 3 μm synthesized ultrafine particle silica was also proposed, but the filling amount was at most 50% by weight, and there were many problems in mechanical strength and durability, and sufficient satisfaction was not obtained.

In recent years, as an inorganic filler having a high filling amount and excellent mechanical strength, a hybrid type using a combination of crushed natural silica having a particle diameter of 10 μm or less and ultrafine silica has been proposed. In this case, the mechanical strength and durability are certainly high, and the cured product has a certain level of surface smoothness because it is prepared with a particle size of 10 μm or less, but it is still said that the aesthetics are comparable to those of natural teeth. Difficulty, and in addition, the use of silica causes insufficient radiopacity. It has also been proposed that the use of spherical silica having a particle size in the range of 0.1 to 1.0 μm provides a dental filling composition having excellent aesthetics and mechanical strength (special feature). Kaisho 5
8-41810). In this case, the surface smoothness and gloss can be satisfied by using relatively small particles, but the filling amount is at most 75% by weight, the mechanical strength is low, the water absorption is high, and durability remains a problem. In addition, silica is not radiopaque and has a large difference in refractive index from the polymerized acrylic monomer, making it difficult to obtain transparency similar to natural teeth. Furthermore, in order to obtain good transparency, it is proposed to use a spherical inorganic oxide having a particle size of 0.1 to 1.0 μm, which mainly contains silica and an oxide of a Group IV metal of the periodic table. (JP-A-62-89)
701). In this case, the transparency is good by adjusting the refractive index, and the surface smoothness and the gloss are not problematic. In addition, the opacity to X-ray can be satisfied by using zirconia or the like. However, the filling amount still does not reach 75% by weight, and the bending strength is 900 kg / cm ² at most, and the mechanical strength is low. Furthermore,
Particles having a particle size of 1 to 100 μm and the above-mentioned particle size of 0.1 to
Proposals have also been made to improve the fluidity and increase the content of the filler inside the tubules such as dentinal tubules by using spherical particles of 1.0 μm in combination (JP-A-61-14810).
9). However, this proposal is aimed at fluidity and a high content of filler in the thin tube, and the bending strength is at most 100.
The mechanical strength is as low as 0 kg / cm ^2, and when it is inferred from the use of particles having a considerably large average particle diameter, the surface smoothness is unsatisfactory as in the hybrid type described above. As described above, the cured product has mechanical strength and aesthetic properties comparable to those of natural teeth.
Dental filling compositions having radiopacity have not yet been obtained.

[0004]

DISCLOSURE OF THE INVENTION PROBLEMS TO BE SOLVED BY THE INVENTION The inventors of the present invention have conducted diligent research to solve the above-mentioned problems, and as a result, have found that a mixture composed of a combination of spherical inorganic oxides having a specific composition and particle size is used. The present invention has been completed by finding that such problems are solved when it is used as a filler, and the purpose thereof is that the filling amount of the inorganic filler is high and the surface smoothness of the cured product is high. Excellent in aesthetics such as gloss and transparency, mechanical strength and durability, as well as excellent X
A dental filling composition having radiopacity is provided. Other objects and effects of the present invention will be apparent from the following description.

[0005]

The above object is a dental filling composition containing a polymerizable monomer and an inorganic filler, wherein the inorganic filler comprises a) an average particle diameter of 1.0 to 50 to 80% by weight of spherical zirconium-containing silicate particles (A) having a size of 5.0 μm, and b) a particle size of 0.5 μm or less, and a particle size of 0.
A dental filling composition characterized by using a mixture with 50 to 20% by weight of spherical silica particles (B) containing 10 to 70% by weight of spherical silica particles of 2 μm or less.

The present invention will be described in detail below. The polymerizable monomer of the present invention is not particularly limited as long as it is used in a dental filling composition, and various monomers are used, but preferably polymerizable vinyl. It is advisable to use monomers. The most typical vinyl monomer is a polymerizable vinyl monomer having an acrylic group and / or a methacrylic group.

For example, monofunctional (meth) acrylates such as methyl (meth) acrylate, ethyl (meth) acrylate, n-propyl (meth) -acrylate, and 2-hydroxyethyl methacrylate, ethylene glycol di (meth). ) Acrylate, triethylene glycol di (meth)
Acrylate, 1,4-butanediol di (meth) acrylate, 1,6-hexanediol di (meth) acrylate, glycerin di (meth) acrylate, trimethylol tri (meth) acrylate, pentaerythritol tetra (meth) acrylate, 2 , 2'-bis [p-
(Γ-methacryloxy-β-hydroxypropoxy) phenyl] propane, bisphenol A dimethacrylate, neopentyl glycol di (meth) acrylate,
2,2'-di (4-methacryloxypolyethoxyphenyl) propane, 1,2-bis (3-methacryloxy-2)
-Polyfunctional (meta) such as hydroxypropoxy) ethane
Acrylate is mentioned, and urethane (meth) acrylate monomers such as a reaction product of 2,2,4-trimethylhexamethylene diisocyanate and oxypropyl methacrylate can also be preferably used. These vinyl monomers may be used alone or as a mixture, if necessary. Further, in the present invention, a polymerization initiator may be used if necessary, and the polymerization initiator to be used is not particularly limited and a known one may be used. As the polymerization means, light energy, a peroxide and an accelerator, or the like can be used.

Another component of the dental filling composition of the present invention is an inorganic filler. The inorganic filler used in the present invention is a) spherical zirconium-containing silicate particles (A) having an average particle diameter of 1.0 to 5.0 μm and b) having a particle diameter of 0.5 μm or less, and particles. The diameter is 0.
It is necessary that the mixture is composed of at least two groups of spherical silica particles (B) containing 10 to 70% by weight of spherical silica particles of 2 μm or less. By using such particles, the filling amount of the inorganic filler is high, the mechanical strength of the cured product and the aesthetics are comparable to those of natural teeth, and the dental filling has excellent radiopacity. A composition can be obtained.

The average particle size of the present invention, which has a large particle size, is 1.0
It is necessary that spherical particles of ˜5.0 μm are zirconium-containing silicates, while spherical particles having a smaller particle diameter of 0.5 μm or less are silica. As a particle having a large particle size, a particle having a small difference in refractive index from a polymer of a monomer used is preferable in order to provide transparency comparable to that of a natural tooth, and at the same time, imparts X-ray opacity. For this purpose, silicate particles containing an element such as zirconium, barium and / or strontium are used.
Zirconium-containing silicate particles are optimal because of the ease of manufacture of spherical particles and the durability of the dental filling composition after curing. The zirconium content of the zirconium-containing silicate particles is preferably 5 to 50% by weight in terms of zirconia. When the zirconium content is less than 5% by weight in terms of zirconia, the refractive index of the polymerized monomer cannot be approached, transparency is insufficient, and clinically necessary X-ray opacity cannot be obtained. On the other hand, 50 in terms of zirconia
If it exceeds the weight percentage, the refractive index of the particles themselves becomes too high,
The refractive index of the polymerized monomer cannot be approached, and only an opaque material can be obtained. On the other hand, silica is most suitable for particles having a small particle size. First, such spherical silica having a small particle diameter has been conventionally known, and its manufacturing method has been established, and stable availability is possible. Regarding transparency, as will be described later, by including particles having a particle size of 0.2 μm or less, the particles have appropriate transparency and give natural aesthetics. In addition, the surface treatment effect of a surface treatment material such as a silane coupling agent is remarkable, and the mechanical strength and durability of the cured product are also significantly improved. In particular, in the case of particles having a small particle size, since the specific surface area thereof becomes large, the influence of the surface treatment effect on the mechanical strength and the like is large, and in this respect also, the use of silica causes other particles to contain, for example, zirconium. It is far superior to the use of silicates, titanium-containing silicates and barium glass. As such silica,
In particular, spherical silica synthesized by hydrolysis polymerization of alkoxysilane is suitable. In addition, it is preferable to use those silicas dried and calcined at 500 ° C. or higher.

The zirconium-containing silicate particles (A) used in the present invention need to have an average particle diameter of 1.0 to 5.0 μm, preferably 1.0 to 3.0 μm. If the average particle size of the particles (A) exceeds 5.0 μm, the smoothness and gloss of the surface of the cured product will be poor, and if the average particle size of the particles (A) is less than 1.0 μm, the surface of the cured product will be poor. The smoothness and gloss are good, but the difference in particle size from the silica particles (B) described below is small, so that the filling amount of the inorganic filler cannot be increased, the mechanical strength is low, and the water absorption property is low. Also, only a filling composition having a problem of durability such as discoloration can be obtained. The reason why the inorganic filler of the present invention gives a high filling amount is considered to be because the smaller particles (B) are sufficiently filled in the gaps formed by the larger particles (A). It is not preferable that the difference in particle size from (B) is small. The zirconium-containing silicate particles described above are synthesized, for example, by hydrolytic polymerization of tetraethyl silicate and tetrabutyl zirconate, but are not limited to this production method. Next, the silica particles (B) of the present invention are sufficiently filled in the gaps of the zirconium-containing silicate particles (A) as described above, and in order to increase the filling amount of the inorganic filler, The particle size needs to be substantially 0.5 μm or less, and more preferably 0.05 to 0.
It is preferably in the range of 5 μm. When the number of particles having a particle size smaller than 0.05 μm in the particles (B) increases,
The specific surface area of the particles (B) tends to increase, the filling amount tends to decrease, and the mechanical strength tends to decrease. Further, the silica particles (B) of the present invention have a wavelength of visible light (about 0.4-0.
10 to 70 of silica particles having a particle diameter of 0.2 μm or less, which is smaller than half of 7 μm) based on the total amount of the particles (B).
It is essential to include the weight%. When the content of the silica particles having a particle diameter of 0.2 μm or less is less than 10% by weight, the cured product of the dental filling composition tends to have a reduced visible light transmittance, and the cured product has a reduced transparency. The aesthetics comparable to the natural tooth which is the object of the invention cannot be obtained. On the other hand, the 0.2
If the content of silica particles having a particle diameter of μm or less exceeds 70% by weight, the specific surface area increases and the filling amount decreases, so that the excellent mechanical strength and durability aimed at by the present invention cannot be obtained. Of the silica particles (B), 0.2 μm
A silica particle having the following particle diameter is (B-1),
When the silica particles having a particle diameter of more than 0.2 μm and not more than 0.5 μm are referred to as (B-2), the particles are the same as the above-mentioned relationship between the zirconium-containing silicate particles (A) and the silica particles (B). When the difference between the particle diameters of (B-2) and particles (B-1) is large, the particles (B-
Since 1) is sufficiently filled and a higher filling amount can be obtained, the average particle diameter of the particles (B-2) is smaller than that of the particles (B
It is preferably at least twice the average particle diameter of -1).
Various methods are used to measure the particle size, particle size distribution, and particle content of zirconium-containing silicate particles and silica particles. As a typical example, a scanning or transmission electron micrograph is used. Examples include, but are not limited to, methods, laser diffraction methods, centrifugal sedimentation methods, and the like.

The zirconium-containing silicate particles (A) and silica particles (B) of the present invention have a spherical shape so that a high filling amount of the inorganic filler and the smoothness of the surface of the cured product of the dental filling composition. It is also suitable for gloss. Furthermore, the zirconium-containing silicate particles (A) of the present invention need to be contained in an amount of 50 to 80% by weight based on the whole inorganic filler, and if it is less than 50% by weight, the filling amount will decrease, and The X-ray opacity cannot be obtained clinically, and the silica particles (B) to fill the voids of the particles (A) are insufficient if the amount exceeds 80% by weight. On the contrary, the filling amount tends to decrease, and
Since the number of relatively large particles increases, the smoothness and gloss of the surface of the cured product also deteriorate, and the aesthetics becomes unsatisfactory. On the other hand, the silica particles (B) of the present invention are 50 to 20% by weight, and 50% by weight, based on the whole inorganic filler.
If it exceeds, the specific surface area of the particles (B) will be large, the filling amount will be low and the mechanical strength will decrease, and if it is less than 20% by weight, the voids of the particles (A) cannot be sufficiently filled and the mechanical strength , The aesthetics are also unsatisfactory. It should be noted that other non-spherical inorganic particles may be added within a range that does not impair the effects of the present invention, and the mixing ratio thereof is preferably 10% by weight or less based on the whole inorganic filler.

The zirconium-containing silicate particles (A) and silica particles (B) of the present invention can be directly mixed and kneaded with a polymerizable monomer to prepare a dental filling composition. It is preferable to previously mix and use the particles (A) and (B) before mixing with the polymerizable monomer in order to obtain a higher filling amount of the inorganic filler. The preliminary mixing method of the particles is not particularly limited such as wet mixing and dry mixing, but mixing in a polar solvent such as alcohols and glycols is effective as the wet mixing method. Further, as the dry mixing method, various kinds of commonly used mixers can be used, and among the air flow type mixers for mixing particles in an air flow, a jet mill type, an air blender type or a jet ohmizer is particularly used. A mold or the like can be preferably used. The reason why the use of the premixed particles gives a high filling amount of the inorganic filler is not always clear, but it is presumed that the particles have a particle distribution in which the smaller particles are easily filled in the spaces between the larger particles. .

The inorganic filler of the present invention is preferably subjected to surface treatment in advance in order to improve dispersibility and mixing with a polymerizable monomer. As such surface treatment,
Organic silicon compound-based surface treatment agents (silane coupling agents) such as γ-methacryloxypropyltrimethoxysilane, vinyltriethoxysilane, vinyltrichlorosilane, and vinylacetoxysilane are preferably used, and the surface treatment method is a usual method. It is possible. Then, the inorganic filler and the polymerizable monomer may be mixed and kneaded to prepare a dental filling composition. The preparation can be carried out by an ordinary method, but it is preferable that the inorganic filler is blended in an amount of 80% by weight or more based on the whole filling composition from the viewpoint of mechanical strength and the like. Further, the composition of the present invention may contain a polymerization inhibitor, a colorant,
An ultraviolet absorber or the like can be added.

[0014]

EXAMPLES Hereinafter, the present invention will be specifically described by way of examples, but the present invention is not limited to the following examples unless it exceeds the gist. In the following Examples and Comparative Examples, spherical zirconium-containing silicate particles synthesized by hydrolytic polymerization of tetraethyl silicate and tetrabutyl zirconate and spherical silica particles synthesized by hydrolytic polymerization of alkoxysilane were used. After the surface treatment of each inorganic particle and the polymerizable monomer were prepared by the method [1], a filling composition was prepared by mixing and kneading, and a test piece was prepared by the method [2]. The measurement was performed.

[1] Surface treatment of each inorganic particle is carried out by mixing and stirring 4% by weight of γ-methacryloxypropyltrimethoxysilane (manufactured by Shin-Etsu Chemical Co., Ltd.) in a water-ethanol solvent with respect to each inorganic particle. Silane-treated inorganic particles were prepared by drying in a hot air drier at 80 ° C. for 2 hours and at 105 ° C. for 5 hours.

Preparation of Polymerizable Monomer Dimethacryloxyethyl trimethylhexamethylene di-
Camphorquinone (Aldri) as a photopolymerization initiator was added to a monomer mixture containing urethane (UDMA: Shin Nakamura Chemical Co., Ltd.) and triethylene glycol dimethacrylate (TEGDMA: Shin Nakamura Chemical Co., Ltd.) in a ratio of 70:30 (% by weight).
ch) 0.5% by weight, N, N-dimethylaminoethyl methacrylate (manufactured by Tokyo Kasei) 0.5 as a polymerization accelerator
Weight% was added to prepare a polymerizable monomer mixture.

[2] 1. Preparation of test piece 1) The compressive strength filling composition was filled into a hole of a stainless steel mold having a hole with an inner diameter of 3 mm and a height of 6 mm, and the upper and lower surfaces were pressure-contacted with a glass plate, and a visible light irradiator Econolite (Yoshida) was used. Light) from both upper and lower surfaces for 40 seconds. The test piece was released from the mold.

2) Bending strength The filling composition was filled in the holes of a stainless steel mold having a thickness of 2 mm, a width of 2 mm, and a length of 25 mm, and the upper and lower surfaces were pressure-contacted with a glass plate, and a photopolymerizer light ace for industrial use ( Light irradiation was performed for 120 seconds on each of the upper and lower surfaces by Yoshida).
The test piece was released from the mold.

3) Water absorption filling composition with a thickness of 3 mm, a width of 15 mm and a length of 20 mm
After filling the holes of the stainless steel mold with the above, and pressing both upper and lower surfaces with glass plates, a test piece was prepared by the same polymerization method as in 2), and each surface was further polished with No. 240 SiC polishing paper.

4) The transparent filling composition was filled into a hole of a stainless steel mold having a hole having an inner diameter of 20 mm and a thickness of 1 mm, and the upper and lower surfaces were pressed with a glass plate, followed by the same polymerization method as in 2). A test piece was prepared. The compressive strength, flexural strength and transparency test pieces were immersed in 37 ° C. water for 24 hours immediately after production, and then subjected to each test. Further, the water absorption rate test piece was stored in the atmosphere at 37 ° C. after the production until the weight reached a constant value and tested.

5) Surface gloss and smoothness The filling composition is cured into a flat plate shape by light irradiation for 20 seconds, and the polished surface by the white point (made by Matsukaze) of the light irradiation plane is visually observed and surface gloss. The test piece was used for measuring roughness (Rmax).

6) The X-ray opaque filling composition was filled into the holes of a stainless steel mold having holes with an inner diameter of 10 mm and a thickness of 1 mm, and the upper and lower surfaces were pressed with glass plates and then the same as 2). A test piece was prepared by the polymerization method.

2. Test method 1) Compressive strength An Instron universal tester (MODEL 4206) was used and the test was performed at a crosshead speed of 2 mm / min. 2) Bending strength Using an Instron universal testing machine (MODEL 4206), the crosshead speed was 0.5 mm / min.

3) Water absorption rate Stored in the air at 37 ° C, when the weight reached a constant value (m ₁ ), immersed in water at 37 ° C and weighed after 24 hours (m ₂ ).
Was measured and the water absorption rate was calculated from the following formula. (M ₂ −m ₁ ) / surface area of test piece 4) Using a transparent color difference meter (MODEL TC-1 manufactured by Tokyo Denshoku),
Lightness (L _W ) when a standard white plate is placed behind the test piece
If, measured lightness (L _B) in the case of placing the standard blackboard behind, was calculated from the following equation. _{(1-L B / L W} ) × 100 In this test method, the more transparency is a large value is high. A value of 25 or more was judged to be excellent, a value of less than 25 to 20 or more was judged to be good, and a value of less than 20 was judged to be defective. 5) Surface gloss and smoothness The surface gloss of the white point polished surface of the test piece was observed with the naked eye, and the polished surface was measured with a surface roughness measuring device (Surfcom 100A manufactured by Tokyo Seimitsu Co., Ltd.) at a standard length of 0.25 mm. The surface roughness (Rmax) was measured. 6) An X-ray opaque X-ray device (Softex SCMB12) was used to photograph the test piece. Human tooth enamel and dentin of the same thickness were also photographed at the same time, and when visually observed, those superior to enamel were excellent, those from enamel to dentin were good, and those inferior to dentin were bad. It was judged.

Examples 1 to 5 The zirconium-containing glass particles shown in Table 1 and the amorphous silica particles shown in Table 2 were mixed and kneaded with the above-mentioned polymerizable monomer in the amount ratio shown in Table 4. Thus, the filling composition was prepared, and the test was performed according to the above items. The results are shown in Table 4. The maximum particle size and average particle size described in Table 1 and Table 2 were determined from the particle size and the number of particles observed in the unit visual field of the scanning electron micrograph of the inorganic filler particles.

Comparative Examples 1 to 8 The inorganic filler particles A, B and C shown in Table 1, Table 2 and Table 3 are mixed and kneaded with the above-mentioned polymerizable monomer in the amount ratio shown in Table 5. Thus, the filling composition was prepared, and the test was performed according to the above items. Each particle was subjected to silane surface treatment in advance according to the surface treatment of each inorganic particle. The maximum particle size and the average particle size are shown in Example 1.
Measured in the same way as ~ 5. The results are shown in Table 5.

[0027]

[Table 1]

[0028]

[Table 2]

[0029]

[Table 3]

[0030]

[Table 4]

[0031]

[Table 5]

As is apparent from Tables 4 and 5, the spherical zirconium-containing silicate particles (A) are contained in an amount of 50 to 80% by weight.
Moreover, the filling composition of the example using the mixed inorganic particles in which the spherical silica particles (B) were blended in the range of 50 to 20% by weight had a filling amount of the filler of 80 as compared with the filling composition shown in the comparative example. Despite the high weight percentage, the strength after curing was high and the water absorption was also very low. In addition, the surface has high gloss, smoothness and transparency, and has excellent aesthetics.
Furthermore, a dental filling composition having clinically sufficient radiopacity and a balance in all respects was obtained.

Example 6 30% by weight of spherical zirconium-containing silicate particles A-I described above and spherical particles having a particle size of 0.4 μm or less and 0.2 μm or less, and further having a particle size of 0.2 μm or less. Spherical silica particles B having an average particle diameter of 0.11 μm and mean particle diameter of 0.2 to 0.4 μm of 0.33 μm
-IV was mixed in advance at a weight ratio of 62/38 by a jet mill type air flow type mixer. The obtained premixed particles were surface-treated by the method [1], and a dental filling composition was prepared using the surface-treated mixed particles thus obtained and the polymerizable monomer [1]. The filler content in the entire composition was 88% by weight. Using the obtained dental filling composition, a test piece is prepared by the above method [2],
When the physical properties were measured, the compressive strength was 3820 kg /
cm ² , bending strength 1550 kg / cm ² , water absorption rate 0.5
It is 7 mg / cm ² , and the transparency is excellent at 30.3,
The surface gloss and smoothness were excellent, and the X-ray opacity was also excellent.

Example 7 The above-mentioned spherical zirconium-containing silicate particles A-IV and spherical silica particles B-V containing 60% by weight of spherical particles having a particle diameter of 0.3 μm or less and 0.2 μm or less were weighed. Ratio 5
The mixture was preliminarily mixed at a ratio of 5/45 by a jet mill type air flow type mixer. The obtained premixed particles were surface-treated by the method [1], and a dental filling composition was prepared using the surface-treated mixed particles thus obtained and the polymerizable monomer [1]. The filler content in the entire composition was 86% by weight. Using the obtained dental filling composition, a test piece was prepared by the method described in [2] above, and its physical properties were measured. Compressive strength 3610 kg / cm ² , bending strength 1510 kg / cm ² , water absorption 0 0.62 mg / cm
² , the transparency was excellent at 38.7, the surface gloss and the smoothness were excellent, and the X-ray opacity was also excellent.

[0035]

EFFECTS OF THE INVENTION According to the present invention, in the dental filling composition in which the zirconium-containing silicate particles and the silica particles specified in the present invention are mixed with the polymerizable monomer in a specific ratio, spherical large particles are used. Since the small particles that do not affect the transparency are efficiently filled in the gaps between them, the filling amount of the inorganic filler can be increased, the mechanical strength is high and the water absorption is low, and the gloss of the surface of the cured product and A well-balanced dental filling composition that has excellent smoothness, high transparency, and aesthetics comparable to natural teeth, and also has X-ray opacity that is clinically necessary, and can be used in all areas. The thing is obtained.

─────────────────────────────────────────────────── ─── Continuation of the front page (56) Reference JP-A-4-210609 (JP, A) JP-A-3-258707 (JP, A) JP-A-2-132102 (JP, A) JP-A-63- 88110 (JP, A) JP 61-171404 (JP, A) JP 61-148109 (JP, A) JP 58-41810 (JP, A) JP 62-89701 (JP, A) JP 60-233007 (JP, A) Special Table 61-501090 (JP, A) (58) Fields investigated (Int.Cl. ⁷ , DB name) A61K 6/00

Claims (3)

(57) [Claims] 1. A dental filling composition comprising a polymerizable monomer and an inorganic filler, wherein the inorganic filler is a) spherical zirconium having an average particle diameter of 1.0 to 5.0 μm. The content of the silicate particles (A) is 50 to 80% by weight, and b) the particle diameter is 0.5 μm or less, and the particle diameter is 0.
A dental filling composition characterized by using a mixture with 50 to 20% by weight of spherical silica particles (B) containing 10 to 70% by weight of spherical silica particles of 2 μm or less. 2. The dental filling composition according to claim 1, wherein the inorganic filler is blended in an amount of 80% by weight or more based on the whole filling composition. 3. The dental filling composition according to claim 1, wherein spherical zirconium-containing silicate particles containing 5 to 50% by weight of zirconium in terms of zirconia are used.