JP3407203B2 - β-maltose hydrated crystal-containing powder, its production method and use - Google Patents

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a β-maltose hydrous crystal-containing powder, a method for producing the same, and uses thereof. More specifically, it is powdered by a spraying method, has excellent solubility in an aqueous medium, and is easy to handle. TECHNICAL FIELD The present invention relates to a powder containing β-maltose hydrous crystals, a method for producing the powder, and use of the powder in various compositions such as food and drink, cosmetics, and pharmaceuticals, which are dissolved and contained in an aqueous medium.

[0002]

2. Description of the Related Art Conventionally, a large amount of sugar has been consumed as a sweetener. However, sugar has such drawbacks that it is too sweet to meet recent tastes and is a main inducer of caries.

In recent years, it has been proposed to use various sugars in order to eliminate the drawbacks of sugar. In particular, maltose produced from starch has a weaker sweetness than sugar and may cause caries. It has features such as low amount and good flavor. Currently, food grade β-maltose hydrous crystal-containing powder is commercially available from Hayashibara Shoji Co., Ltd. under the registered trademarks “Sanmalto” and “Sanmalto S”. Is
Further expansion of the consumption can be expected.

The β-maltose hydrous crystal-containing powder is usually produced from a maltose-containing aqueous solution as a raw material by a syrup system, a cutting system or a spray system.

Among these, the honey-concentration method concentrates a raw material maltose-containing aqueous solution and gradually cools it while stirring under the condition that β-maltose hydrous crystals coexist as seed crystals to crystallize β-maltose hydrous crystals. This is a method for producing a powder, which is a prepared musket, which is separated into crystals and honey by centrifugation or the like, and the crystal part is collected and dried. Although this method can obtain extremely high-purity crystal powder, it has a drawback that the yield of β-maltose hydrous crystal powder is low because it produces honey as a by-product.

On the other hand, in the cutting method and the spraying method, usually, the raw material maltose-containing aqueous solution is concentrated and made into a mass kit, and in the cutting method, the whole amount is solidified, aged, cut and dried to obtain a powder. Or a method of producing a powder, in which, in the spraying method, a spray-dried mass kit is aged and then collected. Although these methods cannot improve the purity of maltose, the whole amount can be powdered and honey is not produced as a by-product, which is industrially advantageous.

More specifically, regarding the cutting method, usually, an aqueous solution containing maltose is concentrated, and β-maltose hydrated crystals are added as seed crystals to partially crystallize β-maltose hydrated crystals. Is solidified and aged in the form of a block, which is cut, dried and sieved to produce a stable β-maltose hydrous crystal-containing powder. Products industrially produced by this cutting method,
It is sold by Hayashibara Shoji Co., Ltd. under the registered trademark "San Marto". According to this cutting method, the whole amount of the raw material maltose can be pulverized, which is industrially advantageous, but this cutting method requires a long time of 5 to 15 days for solidifying and aging the musket in a block shape. Not only does it take a long time, but it also has the drawback of requiring complicated steps for subsequent cutting, drying and sieving.

On the other hand, as for the spraying method, conventionally, a maltose-containing aqueous solution was concentrated, and β-maltose hydrated crystals were added as seed crystals to partially crystallize the β-maltose hydrated crystals, which was then sprayed. A method for producing a powder containing β-maltose hydrous crystals by drying, pulverizing, and aging has been known (Japanese Patent Publication No. 54-3937, Japanese Patent Publication No. 27325/54). This spraying method is industrially most advantageous because it does not require a long period for solidifying and aging the musket, but it still takes 3 to 4 days for its production, and the spraying method allows smooth and continuous operation. It was difficult to produce a powder.

After that, in order to improve this, the contents of sugars other than maltose, specifically, glucose, maltotriose, and oligosaccharides having a degree of glucose polymerization of 4 or more are reduced as much as possible, and converted into an anhydride. By using an extremely high-purity maltose-containing aqueous solution having a maltose content of about 95 w / w% (hereinafter, w / w% is simply abbreviated as “%” unless otherwise specified). , A method for producing a powder containing β-maltose hydrous crystals by a spraying method in a relatively short time was established, and it was sold by Hayashibara Shoji Co., Ltd. under the registered trademark “San Marto S”. However, according to the findings that the present inventors have found for the first time, the β-maltose hydrous crystal-containing powder obtained by this spraying method is unexpectedly not always satisfactory in solubility in an aqueous medium, It was found that there is a need to further improve the sex.

[0010]

DISCLOSURE OF THE INVENTION The present invention has been made to solve the drawbacks of the above-mentioned spraying method newly found by the present inventors, and is an industrially advantageous and inexpensive spraying method. It is an object of the present invention to provide a β-maltose hydrous crystal-containing powder which has excellent solubility in an aqueous medium and is easy to handle, a method for producing the same, and an application thereof.

[0011]

[Means for Solving the Problems] In order to solve the above problems, the present inventors have studied various physical properties of powders containing β-maltose hydrous crystals, which are powdered by a spraying method, and particularly, maltose as a raw material. Focused on the relationship between the sugar composition of the contained aqueous solution and various physical properties of the obtained powder, intensive research was conducted. That is, a musket prepared from a maltose-containing aqueous solution of various sugar compositions is powdered by a spraying method, first kept in a relatively low humidity and high temperature atmosphere, and then obtained in a relatively high humidity and low temperature atmosphere. -Maltose hydrous crystal-containing powder was collected, and various properties of the powder such as hygroscopicity, stickiness, solubility, α-anomer content, and crystallinity were investigated in detail.

As a result, β-maltose hydrous powdered by a spraying method, containing maltose 86% or more and less than 93% and glucose 2% or more and a crystallinity of 62% or more and less than 72% in terms of anhydride. The crystal-containing powder was found to be a powder that has excellent solubility in an aqueous medium and is easy to handle. As a method for producing the powder, maltose is 86% or more and less than 93% and glucose is 2% as an anhydride. An aqueous solution containing the above is used as a mass kit in which β-maltose hydrated crystals are crystallized, then powdered by a spraying method, and further kept in a high temperature atmosphere with relatively low humidity,
A powder having a high α-anomer content in maltose was prepared, and then
Maintaining a relatively high humidity and low temperature atmosphere, the α-anomer content in the maltose of the sprayed powder was reduced to 7% or more and less than 14%, and the obtained crystallinity was 62% or more and 72%.
Established a method for producing a β-maltose hydrous crystal-containing powder, characterized in that the powder of less than is collected, in addition, the β-maltose hydrous crystal-containing powder obtained by the production method of the above, or in an aqueous medium. The present invention was completed by establishing a composition that was dissolved and contained.

[0013]

BEST MODE FOR CARRYING OUT THE INVENTION The maltose-containing aqueous solution used as the raw material for the powder containing β-maltose hydrous crystals of the present invention is powdered by a spraying method, and is 86% or more and less than 93% maltose and 2% glucose in terms of anhydride. Any powder containing the above and having a crystallinity of 62% or more and less than 72% and containing a β-maltose hydrous crystal can be used. As a method for producing such a maltose-containing aqueous solution, for example, Japanese Patent Publication No. 54- Japanese Patent No. 3937, Japanese Patent Publication No. 56-281
No. 53, Japanese Patent Publication No. 57-3356, and Japanese Patent No. 25
As disclosed in Japanese Patent Publication No. 18646, various starches are heated and gelatinized, and then α-amylase (EC.3.
2.1.1) or liquefaction by acid or mechanical force to the lowest possible hydrolysis rate, and then β-amylase (EC 3.2.1.2) and starch debranching enzyme (pullulanase EC 3.2.1.41 or isoamylase E
C. 3.2.1.68) to act to saccharify and produce.

The aqueous solution containing 86% or more and less than 93% of maltose and 2% or more of glucose in terms of an anhydride, as referred to in the present invention, is produced from starch as described above, and usually maltotriose is used as another sugar. And glucose degree of polymerization 4
It contains the above oligosaccharides and the like. The maltotriose and the oligosaccharide having a degree of glucose polymerization of 4 or more easily inhibit the crystallization of β-maltose hydrous crystals from the maltose-containing aqueous solution, and therefore it is desirable to reduce the content as much as possible. In particular, regarding maltotriose, The content is preferably less than 2% in terms of anhydride.

Maltotriose and glucose degree of polymerization 4
Examples of methods for reducing the content of oligosaccharides described above include Japanese Patent Publication No. 56-28154 and Japanese Patent No. 26965.
As disclosed in Japanese Patent No. 30, etc., maltotriose or an oligosaccharide having a glucose polymerization degree of 4 or more acts relatively well, and an enzyme that decomposes them to produce glucose, maltose, or the like is acted, It is possible to decrease the content of maltotriose or oligosaccharide having a degree of glucose polymerization of 4 or more and increase the content of maltose. Further, it is also possible to separate and remove maltotriose or oligosaccharides having a degree of glucose polymerization of 4 or more by using a UF membrane, a reverse osmosis membrane, activated carbon or the like, and JP-B-62-5112.
As disclosed in Japanese Patent Publication No. 0, Japanese Patent Publication No. 5-79316, and the like, maltotriose or higher oligosaccharides can be separated and removed by a chromatographic separation method using an ion exchange resin.

One of the features of the present invention is that a maltose content of 86% or more and 93% or more in terms of anhydride is obtained by adopting a series of manufacturing methods in which the following steps are combined and increasing the crystallization rate of maltose. Less, in other words, a spraying method despite the fact that sugars other than maltose such as glucose, maltotriose, and oligosaccharides having a glucose polymerization degree of 4 or more coexist in a relatively large amount of 7% or more and less than 14%. Thus, the β-maltose hydrous crystal-containing powder having excellent solubility and easy handling can be easily produced in a relatively short time.

That is, a series of production methods are as follows: (a), a maltose-containing aqueous solution having a sugar composition used in the present invention is used as a mass kit, and then (b), a spraying method, preferably spraying using a high pressure nozzle or a rotating disk. Powdered by a drying method, preferably less than 10% water content, more preferably about 5-9
% Powder, and further, in order to increase the crystallization rate of maltose contained therein, (c), this is a relatively low humidity, high temperature atmosphere, preferably a relative humidity (RH) of less than 40%, more preferably Is less than 20%, preferably 75 ° C
And more preferably in an atmosphere of 80 to 110 ° C.
For about 4 hours, a powder having a high content of α-anomer which is a maltose isomer, preferably α-anomer in maltose
Powder with an anomer content of 35% or more, then
(D) a relatively high humidity and low temperature atmosphere, preferably an atmosphere having a relative humidity (RH) of more than 70%, more preferably 80% or more, preferably less than 50 ° C., more preferably 20 to 45 ° C. For about 5 to 10 hours to reduce the α-anomer content in the maltose to 7% or more and less than 14%, and (e) the obtained crystallinity is 62% or more 7% or more.
This is achieved by collecting powder containing less than 2% β-maltose hydrous crystals.

The above steps will be described in more detail below. In the step (a), the maltose-containing aqueous solution is concentrated to form a concentrated solution having a water content of 15 to 30%, and a suitable amount of β-maltose hydrated crystals as seed crystals, usually about 0.1 to 5%. Is co-existing and gradually cooled and stirred to produce a mass kit. At this time, the crystallization rate of the β-maltose hydrated crystal (hereinafter, unless otherwise specified, the crystallization rate means that the muskit is separated into crystals and honey, and the (crystal anhydrate weight / mass kit) Anhydrous weight) x 1
00 value. The higher the), the higher the viscosity of the musket.

Further, in the step (b), the inventors of the present invention heat and raise the temperature of a highly viscous mass kit containing β-maltose hydrous crystals within a range that does not substantially lower the crystallization rate. It was found that the β-maltose hydrous crystal-containing powder can be easily produced by the spraying method by decreasing the viscosity. That is, the present inventors have found that when the musket is heated and the temperature is raised, the viscosity immediately decreases as the temperature rises, but the produced crystals do not dissolve in a short time even if the temperature rises to some extent, and the crystallization rate It was found that the viscosity of the musket was increased by raising the temperature of the musket without substantially decreasing the crystallization rate, preferably 50,000 cp (hereinafter, particularly, in this specification, Unless otherwise noted, the viscosity cp is a value measured by using a BH type rotational viscometer and rotating at 4 rpm using a No. 7 rotor.)
It has been clarified that the spraying operation is easy and the drying efficiency can be improved.

The method of raising the temperature is not particularly limited. For example,
Pour warm water into the jacket of the auxiliary crystal machine containing the mask kit,
A known method such as directly adding steam into the auxiliary crystallizer or heating with a heat exchanger between the auxiliary crystallizer and the liquid feeding pump can be appropriately adopted. The degree of temperature rise may be such that the viscosity of the musket can be sprayed, specifically, 50,000 cp or less, preferably 40,000 cp or less, usually 2 to 15 ° C., preferably 2 to 10 ° C. It is suitable to carry out as short a time as possible so that the crystallization rate does not decrease in the range of.

In the step (c), the powder is contacted with a small amount of anhydrous crystals of α-maltose to obtain α in maltose.
-Adopting a method that promotes isomerization to the anomer can also be advantageously carried out. The maltose isomers include α-anomer and β-anomer. As the crystal form, α-maltose anhydrous crystal, β-maltose hydrous crystal, β-maltose anhydrous crystal, and α-maltose and β
-Α and β complex crystals in which maltose coexists at a constant ratio are known.

7% or more of α-anomer in maltose 1
The content of less than 4% means the content of α-anomer in maltose, regardless of whether the form is amorphous or crystalline. Generally, when the content of α-anomer in maltose is 14% or more, it means that a large amount of amorphous maltose or an anhydrous α-maltose crystal is contained, and conversely, maltose is contained. When the content of α-anomer is less than 7%, the rest is β-maltose, which means that the content of β-maltose hydrate or anhydrous crystal is high.

Further, in the step (d), the α-anomer content in maltose is reduced to 7% or more and less than 14% by keeping it for about 5 to 10 hours, and then a drying step is further added if necessary. Can also be implemented advantageously.

In the step (e), the obtained β-
The maltose hydrous crystal-containing powder was subjected to a particle size distribution test (“industrial analysis method for starch sugar”, issued in 1991, according to the method for measuring particle size distribution described in Food Chemistry Newspaper, page 118,
Using a JIS Z8801 sieve, sample 50 g
It measured by sieving for a minute. In (1), a large amount of powder having a relatively large particle size is contained, and usually 60% or more of powder exceeding 106 μm is contained, and in many cases, 40% or more of powder exceeding 150 μm and 300 μm or less is contained. Further, the powder of more than 150 μm and 300 μm or less often contains agglomerates formed by a plurality of particles adhering and agglomerating during the process of falling in the spray dryer or in the process from aging to completion of drying.

The β-maltose hydrous crystal-containing powder of the present invention thus obtained has excellent solubility in an aqueous medium,
Moreover, the powder has good storage stability and fluidity and is easy to handle.

The aqueous medium in the present invention means a liquid, paste-like, semi-solid or solid substance containing a large amount of water or water capable of dissolving and containing the powder containing β-maltose hydrous crystals. To do. In particular, the viscous aqueous medium includes, for example, sugars, starches, fats, proteins, polyphenols and emulsifiers, and specifically, for example, gelatinized starch used for fertilization, rice cake, etc.,
Wheat flour, dough prepared from starch-rich powder such as rice flour, dough, noodles, etc., raw bean paste, fish meat, grated meat such as livestock meat, liquid egg, milk cream, fermented milk, peanut paste,
Examples include fruit pulp, vegetable pulp, sugar syrup, and extract concentrate.

The β-maltose hydrous crystal-containing powder of the present invention has excellent solubility in an aqueous medium having the above-mentioned viscosity, and is used not only for this but also advantageously for use in an aqueous medium having a low viscosity. Available. Further, it has a good quality and elegant sweetness and also has an action of inhibiting the production of dextran, which is one of the causes of tooth decay, and is suitably used as a sweetener which hardly causes tooth decay.

The β-maltose hydrous crystal-containing powder of the present invention can be advantageously used as a sugar-coating agent for tablets in combination with a known binder such as pullulan, hydroxyethyl starch, polyvinylpyrrolidone and the like. Furthermore, the β-maltose hydrous crystal-containing powder of the present invention is useful in terms of osmotic pressure controllability, shapeability, luster-imparting property, moisturizing property, viscosity, sugar crystallization preventing property, aging preventing property of gelatinized starch and the like. It also has properties.

Therefore, the β-maltose hydrous crystal-containing powder of the present invention can be used as a sweetener, a taste improver, a flavor improver, a quality improver, a stabilizer, an excipient, etc. in foods, feeds, feeds,
It can be advantageously used for various compositions such as cosmetics, pharmaceuticals, and luxury items.

The β-maltose hydrous crystal-containing powder of the present invention can be used as a seasoning for sweetening various articles as a specific use. If necessary, for example, starch syrup, glucose, fructose, lactosucrose, sucrose, trehalose, isomerized sugar, honey, maple sugar, isomalt oligosaccharide, galactooligosaccharide, fructooligosaccharide, sorbitol, maltitol, lactitol, dihydrochalcone, Stevioside, α-glycosyl stevioside, rebaudioside, glycyrrhizin,
One or two other sweeteners such as L-aspartyl-L-phenylalanine methyl ester, sucralose, acesulfame K, saccharin, glycine, alanine, etc.
Combined with more than one seed, if necessary, dextrin,
It is also optionally used in combination with one or more fillers such as starch, sugar and lactose.

The β-maltose hydrous crystal-containing powder of the present invention may be used as it is or, if necessary, in combination with one or more appropriate fillers, excipients, binders, sweeteners and the like. Then, it may be optionally used by molding into various shapes such as granules, spheres, short rods, plates, cubes, tablets, films or sheets.

Furthermore, the sweetness of the powder containing hydrous crystals of β-maltose of the present invention is in good harmony with various substances having other tastes such as sourness, salt, taste, astringency, umami, bitterness, and various foods and drinks. It can be used for sweetening, taste improvement, and quality improvement. Specifically, for example, amino acids, peptides, soy sauce, powdered soy sauce, miso, powdered miso, moromi,
Hishio, sprinkle, mayonnaise, dressing, vinegar,
Three cup vinegar, powdered sushi vinegar, Chinese broth, Tentsuyu, noodle soup, sauce, ketchup, grilled meat sauce, curry roux, stew broth, soup broth, dashi broth, nucleic acid-based seasoning, complex seasoning, mirin, new mirin, It can be advantageously used as various seasonings such as table sugar and coffee sugar. Also, for example, rice crackers, hail, rice cakes, manju,
Japanese sweets such as uiro, bean paste, yokan, mizuyo, nishikidama, jelly, castella, candy, etc., bread, biscuits, crackers, cookies, pies, pudding, butter cream, custard cream, cream puffs, waffles, sponge cakes. , Donut, chocolate, chewing gum,
Western sweets such as caramel and candy, ice cream, frozen desserts such as sorbet, syrup pickles of fruit, syrups such as ice honey, flower paste, peanut paste, fruit paste, pastes such as spreads, jam, marmalade, syrup pickles, sugar fruit Processed foods of fruits, vegetables, etc., Fukugami pickles, Bettara pickles, Senmai pickles,
Pickles such as rakuke pickles, pickled pickles, pickled pickles such as Chinese cabbage pickles, livestock products such as ham and sausages, fish ham, fish sausages, fish meat products such as kamaboko, chikuwa, tempura, sea urchin, Various delicacies such as salted squid, vinegared konbu, simmered squid, dried swelling syrup, seaweed, wild vegetables, sardines, small fish, prepared fish such as shellfish, boiled beans, potato salad, prepared foods such as kelp rolls, yogurt , Dairy products such as cheese, fish meat, meat, fruits, vegetables bottling, canned products, sake, synthetic liquor, liquor such as liquor, coffee, tea, cocoa, juice, carbonated drinks,
Lactic acid drinks, soft drinks such as lactic acid bacteria drinks, pudding mixes, hot cake mixes, instant foods such as instant shiruko, instant soup, and further baby food, therapeutic foods, drinks,
It can be advantageously used for various foods and drinks such as peptide foods, frozen foods and health foods.

Further, it can also be used for the purpose of improving the palatability of feed, feed and the like for domestic animals, poultry, other bees, silkworms, fish and other domestic animals. In addition, tobacco, toothpaste, lipstick, lip balm, oral solution, tablets, troches,
Liver oil drop, mouth-cooling agent, mouth-flavoring agent, as a sweetener for various solid substances such as mouthwash, or a taste improver thereof.
It can be advantageously used as a corrigent, a quality improver, a stabilizer and the like.

The β-maltose hydrous crystal-containing powder of the present invention is stable and high by blending it as a quality improver and / or stabilizer into health foods, pharmaceuticals and the like containing active ingredients, active ingredients or physiologically active substances. It is possible to obtain a quality liquid, pasty or solid health food or medicine. Examples of the active ingredients and physiologically active substances include interferon-α, interferon-β, interferon-γ, TNF-α, TNF-β, macrophage migration inhibitory factor, colony stimulating factor, transfer factor, lymphokines such as interleukin, Insulin, growth hormone, prolactin, erythropoietin,
Hormones such as egg cell stimulating hormone, BCG vaccine,
Japanese encephalitis vaccine, measles vaccine, live polio vaccine, pox seedling, tetanus toxoid, hub antitoxin, biologics such as human immunoglobulin, penicillin, erythromycin, chloramphenicol, tetracycline, streptomycin, antibiotics such as kanamycin sulfate, Vitamins such as thiamine, riboflavin, L-ascorbic acid, α-glycosyl ascorbic acid, liver oil, carotenoid, ergosterol, tocopherol, rutin, α-glycosyl rutin, naringin, α-glycosyl naringin, hesperidin, α-glycosyl hesperidin,
Lipase, elastase, urokinase, protease, β-amylase, isoamylase, glucanase,
Enzymes such as lactase, ginseng extract, bamboo extract, plum extract, pine extract, terrapin extract, chlorella extract,
Examples thereof include extracts such as aloe extract and propolis extract, viable bacteria such as virus, lactic acid bacterium and yeast, royal jelly and the like.

The method for incorporating the β-maltose hydrous crystal-containing powder of the present invention into the various compositions described above may be incorporated in the steps until the completion of these compositions. For example, mixing, dissolving, Known methods such as melting, dipping, infiltration, spraying, coating, coating, spraying, pouring, crystallization, and solidification are appropriately selected. The amount thereof is usually 1% or more, preferably 2% or more, more preferably 5 to 9% by weight of the composition.
It is preferable to add 9%.

The present invention will be described in detail below by using concrete experiments.

[0037]

[Experiment] <Effect of raw sugar composition on physical properties of various β-maltose crystal-containing powders> The effect of raw sugar composition on physical properties of various β-maltose crystal-containing powders was investigated by a spraying method. As the test powder, various raw material maltose-containing aqueous solutions having different sugar compositions were prepared and used as a powder containing β-maltose hydrous crystals by a spraying method. The maltose-containing aqueous solution is commercially available purified maltose (registered trademark "San Marto S" by Hayashibara Shoji Co., Ltd.), or this purified maltose contains glucose (special grade reagent sold by Wako Pure Chemical Industries, Ltd.), maltotriose, maltotetraose. And / or maltopentaose (both are reagents manufactured by Hayashibara Biochemical Laboratory Co., Ltd.) was used to prepare maltose-containing aqueous solutions having various compositions.

The β-maltose hydrous crystal-containing powder was prepared by the spraying method as follows. That is, the maltose-containing aqueous solution as a raw material was concentrated to a water content of 25% and then transferred to an auxiliary crystallizer, and 1% of β-maltose hydrated crystal was added as a seed crystal. While slowly stirring, the temperature was gradually lowered to 30 ° C. The β-maltose hydrous crystal was partially crystallized over 18 hours to obtain a musket. The crystallization rate of the musket was 36 to 43%. After the completion of the auxiliary crystallization, for the musket having a viscosity of more than 50,000 cp, the viscosity is increased to about 45,000 cp without substantially reducing the crystallization rate by heating before sending with a high-pressure pump. It was lowered and sprayed using a pressure nozzle. The temperature of the hot air for drying at the time of spraying is 75 ° C, the hot air blowing method is a vertical downward flow in the spray dryer, and the amount of air blown is such that the water content of the dry powder when taken out from the spray dryer is about 8.5%. Adjusted to.

The obtained powder is immediately seeded with α-
Maltose anhydrous crystal 0.2% mixed and contacted, temperature 9
Stored in a thermo-hygrostat at 0 ° C. and 20% relative humidity (RH) for 2 hours, and then kept in a thermo-hygrostat at 30 ° C. and 80% relative humidity (RH) for 5 hours to ripen and β- A maltose-containing hydrous crystal-containing powder was obtained. This powder was subjected to various physical property tests described below.

In the physical property test, as a control, purified maltose (registered trademark "San Marto S" manufactured by Hayashibara Shoji Co., Ltd.), reagent β-maltose hydrous crystal (manufactured by Hayashibara Biochemical Laboratory Co., Ltd., trade name "Maltose HHH") ) And α
-Anhydrous maltose crystals (registered trademark "Fine Tose", sold by Hayashibara Shoji Co., Ltd.) were used.

The physical property test was conducted by the following methods. A. For sugar composition analysis, KS-801 column (Showa Denko)
Alternatively, liquid chromatography using a CH04SS column (manufactured by MCI) was performed, and the sugar composition was determined from the area ratio of the chromatogram.

B. In the hygroscopicity test, the sample placed in an aluminum cup was not covered, but it was placed in a desiccator adjusted to RH75.2% (equilibrium with saturated sodium chloride aqueous solution) and allowed to stand at 25 ° C for 3 days. Measure
The rate of weight increase (%) with respect to the original sample was determined and taken as hygroscopicity.

C. The adhesiveness is determined by visually observing the condition of the sample in the aluminum cup taken out after being left for 3 days in the hygroscopicity test,
If the sample was solidified by absorbing moisture as compared with that before the test, it was determined to have the adhesiveness.

D. For the solubility test (i), as the solubility test in water, 5 ml of deionized water at 25 ° C. was placed in a plastic test tube, and 1 g of maltose crystal-containing powder having various sugar compositions was added at once to the powder to complete the test. It was submerged in water and sealed, and this was held in a constant temperature bath at 50 ° C., and the dissolved state of the powder was visually observed every 20 minutes. For the evaluation, the time (minutes) required until the powder was completely dissolved and became transparent was obtained. As a criterion for evaluation, it was judged that the shorter the time it took for the powder to melt and disappear, the better the solubility.

(Ii) As a solubility test for an aqueous solution containing dextrin, 5 ml of an aqueous solution of dextrin (product name "Paindex # 1" manufactured by Matsutani Chemical Industry Co., Ltd.) with a concentration of 17% having viscosity was placed in a plastic test tube. To this, 1 g of powder containing maltose crystals of various sugar compositions was added in the same manner as in the case of the above-mentioned (i) solubility test in water, and the powder was completely submerged in water and tightly plugged.
The powder was kept in a constant temperature bath at 0 ° C., and the state of the powder was visually observed.
The evaluation criteria were the same as in the case of the water solubility test (i).

E. Maltose isomers were analyzed by dissolving the sample in anhydrous pyridine and subjecting it to TMS treatment to obtain 2% OV.
Gas chromatography using -17 Chromosolve W (AW-DMCS) was performed, and the α, β-anomer ratio was determined from the area ratio of the chromatogram.

F. The crystallinity of the powder is measured by using the X-ray diffractometer Geiger Flex RDA-IIB (using Cu and Kα rays) (manufactured by Rigaku Denki Co., Ltd.) based on the powder X-ray diffraction pattern by the method of Ruland. (Actor
Chris Crografica: Acta Crystallo
graphica, Vol. 14, p. 1180, 1961.
Year). Among the measured powders, typical powder X-ray diffraction patterns are shown in FIGS. 1 to 5.

The test results for the sugar composition of the starting maltose-containing aqueous solution and the hygroscopicity, stickiness, solubility, α-anomer content, and crystallinity of each powder obtained are shown as physical properties of various maltose crystal-containing powders. Summarized in 1.

[0049]

[Table 1]

As is clear from Table 1, the test No. Oligosaccharides containing maltose 86% or more and less than 93% and glucose 2% or more, and maltotriose and glucose polymerization degree 4 or more as other sugars, which are obtained by the spraying methods of 3 to 6 and are equivalent to anhydrous. Containing 7% or more and less than 14% of α-anomer in maltose as a maltose isomer and having a crystallinity of 62% or more and less than 72% β-maltose hydrous crystal-containing powder have low hygroscopicity and stickiness. It was found that the product has good storage stability, is easy to handle, and has excellent solubility in water and an aqueous medium such as a viscous dextrin-containing aqueous solution. On the other hand, the test No. Maltose content of 1 and 2 is 82.4% and 8
As low as 4.2%, the degree of crystallinity of maltose isomers in which α-anomer content in maltose exceeds 14% is 62%.
The β-maltose hydrous crystal-containing powder obtained by the spraying method of less than was a highly unstable powder having high hygroscopicity, stickiness, and poor storage stability, although it had excellent solubility in an aqueous medium. .

On the other hand, the test No. Maltose content of 7 is 9
It is as high as 4.1%, the α-anomer content in maltose as a maltose isomer is less than 7%, and the crystallinity is 7%.
The β-maltose hydrous crystal-containing powder obtained by the spraying method exceeding 2% has low hygroscopicity and no stickiness,
The powder had poor solubility in an aqueous medium.

Test No. used as a control. 8 "San Marto S" is a powder obtained by a spraying method.
However, the maltose purity was as high as 95.0% and the crystallinity was 74.5%, which showed high hygroscopicity and almost no stickiness, but poor solubility in an aqueous medium. In addition, the test No. 9 "Maltose HHH"
Is a crystalline powder obtained by mashing a musket. This powder is a very high purity maltose, which has a high maltose purity of 99.6% and a high crystallinity of 82.6%, and has almost no hygroscopicity and no sticking property, but is soluble in an aqueous medium. It was inferior in sex. Furthermore, test N
o. Unlike the other samples, 10 "Fine Tose" is an α-maltose anhydrous crystalline powder. This powder has a high α-anomer content in maltose, and the properties of the powder are significantly different from other powders mainly containing β-maltose hydrous crystals, and the hygroscopicity is high in spite of the high crystallinity. The powder was high and had a strong sticking property, was inferior in storage stability and was an unstable powder, and further, was poor in solubility in an aqueous medium.

From the above results, in the production of the β-maltose crystal-containing powder by the spraying method,
A β-maltose crystal having excellent solubility in an aqueous medium and easy handling when produced according to a series of production methods of the present invention using an aqueous solution containing maltose 86% or more and less than 93% and glucose 2% or more as a raw material It has been found that a powder containing can be obtained.

Accordingly, β-containing maltose of 86% or more and less than 93% and glucose of 2% or more and a crystallinity of 62% or more and less than 72%, obtained by adopting the present invention, in terms of anhydride. The maltose crystal-containing powder has excellent solubility in an aqueous medium, is easy to handle, and can be produced in a high yield.In addition, it requires less work time when dissolved in an aqueous medium and used. It can be greatly shortened and can be said to be extremely valuable in industry.

Hereinafter, the present invention will be described in more detail with reference to specific examples, but the present invention is not limited to these examples.

[0056]

[Example A-1-a] <Preparation of maltose-containing aqueous solution>
Commercially available bacterial liquefied α-amylase (trade name “Spitase HS”, in a suspension of potato starch 1 part by weight and water 4 parts by weight)
Add Nagase Sangyo Co., Ltd.) and raise the temperature to 90 ° C to heat and gelatinize, then immediately heat to 130 ° C to stop the enzyme reaction,
A liquefied liquid of DE1.8 was obtained. The starch liquefaction solution was rapidly cooled to 55 ° C., and starch debranching enzyme (isoamylase prepared by culturing Pseudomonas bacteria, sold by Hayashibara Biochemical Laboratories, Inc.) was added at 100 units per 1 g of starch and β-amylase derived from soybean ( Trade name "# 1500", sold by Nagase & Co., Ltd. 50 units per 1 g of starch, and maltose-producing α-amylase (trade name "Maltogenase", sold by Novo Nordisk Co., Ltd.) 10 units per 1 g of sugar In addition, saccharification was performed for 40 hours while maintaining the pH at 5.0. According to a conventional method, this was decolorized by treatment with activated carbon and desalted by treatment with an ion exchange resin for purification, and concentrated under reduced pressure to obtain a maltose-containing aqueous solution. The sugar composition of the maltose-containing aqueous solution is
Glucose was 3.8%, maltose was 92.5%, maltotriose was 1.1%, and maltotetraose was 2.6% or more.

[0057]

[Example A-1-b] <Preparation of β-maltose hydrous crystal-containing powder> The maltose-containing aqueous solution obtained in Example A-1-a was concentrated to a water content of 29% and then transferred to an auxiliary crystal can for seed crystals. As a result, 1% of hydrous β-maltose crystals were added, and the temperature of the musket was gradually lowered to 29 ° C. with slow stirring, and β-maltose hydrous crystals were partially crystallized over 12 hours. The crystallization rate of the Muskit was 37%.
The mass kit after the completion of the auxiliary crystals was sent by a high-pressure pump and sprayed in a spray dryer using a rotating disk. At this time, the temperature of the hot air for drying was 70 ° C., the hot air was blown vertically in parallel in the spray dryer, and the amount of air was adjusted so that the moisture content of the dry powder when taken out from the spray dryer was 7.5%. did.

This powder was immediately mixed and contacted with 0.2% of anhydrous α-maltose crystals, and the temperature was 85 ° C. and the relative humidity (R
H) kept at 20% for 3 hours, and then kept at 30 ° C. and relative humidity (RH) 80% for 5 hours for aging to perform β-maltose having a crystallinity of 71.4% and a water content of 6.1%. The water-containing crystal-containing powder, in terms of the anhydride, with respect to the raw material potato starch,
Obtained with a yield of 96%. This powder contains 92.5% maltose, 3.8% glucose, 1.1% maltotriose, and 2.6% oligosaccharides having a glucose polymerization degree of 4 or more, in addition to maltose isomerization. As a body, it contained 7.8% of α-anomer in maltose and was excellent in solubility in an aqueous medium. Moreover, 25
The powder showed almost no hygroscopicity even when stored under conditions of ° C and relative humidity (RH) of 75.2%, had excellent storage stability, good flowability, and was easy to handle. In addition, as a result of measuring the particle size distribution of the present powder, it was found that the particles contained powder in which fine particles were aggregated, and 41% of particles having a size of 150 μm or more and 300 μm or less were included.

Further, the present powder is excellent in solubility in an aqueous medium as a sweetener, a taste improver, a quality improver, a stabilizer, a discoloration preventing agent, a bulking agent, an excipient, a binder and the like. Therefore, for example, not only a liquid substance containing a large amount of water or water, but also a paste-like substance, a semi-solid substance or a solid substance,
Including, food and drink, favorite food, feed, food, cosmetics,
It can be advantageously used for various compositions such as pharmaceuticals. Furthermore, as it is, or as needed, it is mixed with a filler, an excipient, a binder and the like to give granules, spheres, short rods, plates, cubes,
It is also optional to use it by forming it into various shapes such as tablets.

[0060]

[Example A-2-a] <Preparation of maltose-containing aqueous solution>
Commercially available bacterial liquefaction type α-amylase (trade name “Spitase H” was added to a suspension of 1 part by weight of corn starch and 3 parts by weight of water.
S ”, sold by Nagase & Co., Ltd.) was heated to 90 ° C., gelatinized by heating, and immediately heated to 130 ° C. to stop the enzyme reaction to obtain a liquefied solution of DE2.5. 55 of this starch liquefaction liquid
50 units of starch debranching enzyme (isoamylase prepared by culturing Pseudomonas bacterium, sold by Hayashibara Biochemical Laboratories Co., Ltd.) and β derived from soybean
20 units of amylase (trade name "# 1500", sold by Nagase & Co., Ltd.) was also added and saccharified for 40 hours while maintaining pH 5.0 to obtain a high-purity maltose-containing saccharified solution having a maltose content of 84.6% based on solids. Obtained. The sugar composition of the maltose-containing saccharified solution was as follows: glucose 3.5%, maltose 84.
6%, maltotriose 8.2%, and maltotetraose more than 3.7%.

To this saccharified solution, Taka-amylase A was further added in an amount of 50 units per gram of sugar, and the pH was kept at 5.5, and the enzymatic reaction was allowed to proceed for another 20 hours. According to a conventional method, this was decolorized by treatment with activated carbon, desalted by treatment with an ion exchange resin, purified, and concentrated under reduced pressure to obtain a maltose-containing aqueous solution. The sugar composition of the maltose-containing aqueous solution was glucose 5.
6%, maltose 91.2%, maltotriose 1.3
%, And 1.9% or more of maltotetraose.

[0062]

[Example A-2-b] <Preparation of powder containing β-maltose hydrous crystals> The maltose-containing aqueous solution obtained in Example A-2-a was concentrated to a water content of 26% and transferred to an auxiliary crystallizer to give seed crystals. As a result, 1% of β-maltose hydrated crystal was added, the temperature of the musket was gradually lowered to 30 ° C. with slow stirring, and the β-maltose hydrated crystal was partially crystallized over 14 hours. The crystallization rate of the mask was 41%.
The mass kit after the completion of the auxiliary crystals was sent by a high-pressure pump and sprayed in a spray dryer using a rotating disk. The temperature of the hot air for drying was 75 ° C., the blowing of the hot air was a vertically downward cocurrent flow in the spray dryer, and the amount of the blown air was adjusted so that the water content of the dry powder when taken out from the spray dryer was 8.5%.

This powder was immediately mixed and contacted with 0.2% of anhydrous α-maltose crystals, and the temperature was 90 ° C. and the relative humidity (R
H) held at 25% for 2 hours, then held at 30 ° C. and 80% relative humidity (RH) for 5 hours for aging to perform β-maltose hydrate having a crystallinity of 70.4% and a water content of 6.1%. The crystal-containing powder was obtained at a yield of 95% in terms of anhydride with respect to the raw material corn starch. This powder contained 95.6% maltose, 5.6% glucose, 1.3% maltotriose, and 1.9% oligosaccharides having a degree of glucose polymerization of 4 or more, in addition to maltose isomerization, in addition to maltose isomerization. It contained 9.2% of α-anomer in maltose as a body and was excellent in solubility in an aqueous medium. Moreover,
The powder showed almost no hygroscopicity even when stored at 25 ° C. and a relative humidity (RH) of 75.2%, had excellent storage stability, good flowability, and was easy to handle. In addition, as a result of measuring the particle size distribution of the present powder, it was found that particles having agglomerated fine particles were contained in the particles and that particles having a particle size of 150 μm or more and 300 μm or less were
% Was included.

Further, the present powder is excellent in solubility in an aqueous medium as a sweetener, a taste improving agent, a quality improving agent, a stabilizer, a discoloration preventing agent, a filler, an excipient, a binder and the like. Therefore, for example, not only a liquid substance containing a large amount of water or water, but also a paste-like substance, a semi-solid substance or a solid substance,
Including, food and drink, favorite food, feed, food, cosmetics,
It can be advantageously used for various compositions such as pharmaceuticals. Furthermore, as it is, or as needed, it is mixed with a filler, an excipient, a binder and the like to give granules, spheres, short rods, plates, cubes,
It is also optional to use it by forming it into various shapes such as tablets.

[0065]

[Example A-3-a] <Preparation of maltose-containing aqueous solution>
Commercially available bacterial liquefied α-amylase (trade name “Spitase H” was added to a suspension of 3 parts by weight of corn starch and 7 parts by weight of water.
S ”, sold by Nagase & Co., Ltd.) was heated to 90 ° C., gelatinized by heating and immediately heated to 130 ° C. to stop the enzyme reaction, and a DE4.3 liquefied liquid was obtained. 55 of this starch liquefaction liquid
50 units of starch debranching enzyme (isoamylase prepared by culturing Pseudomonas bacteria, sold by Hayashibara Biochemical Laboratories Co., Ltd.) after being rapidly cooled to ℃, β-amylase derived from soybean (trade name “# 1500”) Also, 20 units of Nagase Sangyo Co., Ltd. was added and the mixture was saccharified for 40 hours while maintaining the pH at 5.0 to obtain a saccharified solution having a maltose content of 84.6% based on solids. According to a conventional method, this was decolorized by treatment with activated carbon, desalted by treatment with an ion exchange resin, purified, and concentrated under reduced pressure to obtain a maltose-containing aqueous solution having a sugar concentration of 45%, which was used as a fractionation raw material.

The fractionation resin used for the fractionation was an alkali metal type strongly acidic cation exchange resin (sold by Organo Corporation, trade name "Amberlite XT-1007 (Na ⁺ type)", crosslinking degree 6%). Use a stainless steel column with an inner diameter of 5.4 cm filled with a water suspension and connect the two columns so that the aqueous sugar solution flows in series to make the total length of the resin layer 1
It was set to 0 m.

While maintaining the temperature in the column at 55 ° C., 5 v / v% of the raw sugar solution was added to the resin,
Fractionation is carried out by flowing warm water at 5 ° C with SV0.3, and the maltotriose-rich fraction is separated and removed to have a high maltose content and a high maltose content including oligos and the like. Fractions were collected. Then, according to the usual method,
The product was decolorized by treatment with activated carbon, desalted by treatment with an ion exchange resin, purified, and concentrated under reduced pressure to obtain a maltose-containing aqueous solution. The sugar composition of this maltose-containing aqueous solution was glucose 6.0%, maltose 90.1%, maltotriose 0.8%, and maltotetraose 3.1% or more.

[0068]

[Example A-3-b] <Preparation of β-maltose hydrous crystal-containing powder> The maltose-containing aqueous solution obtained in Example A-3-a was concentrated to a water content of 24% and then transferred to an auxiliary crystallizer to seed crystals. As a result, 1% of β-maltose hydrated crystals was added, and the temperature of the musket was gradually lowered to 29 ° C. with slow stirring, and β-maltose hydrated crystals were partially crystallized over 15 hours. The crystallization rate was 40%. Since the mass kit after the completion of the eutectic has a high viscosity, it is heated by a high-pressure pump when the solution is sent, and the crystallization rate is reduced to about 40,000c.
While lowering the viscosity to p, it was sprayed in a spray dryer using a pressure nozzle. The temperature of the hot air for drying at this time is 75
C., hot air was blown vertically downward in the spray dryer, and the amount of blown air was adjusted so that the water content of the dry powder when taken out from the spray dryer was 9.0%.

This powder was immediately mixed and contacted with 0.2% of anhydrous α-maltose crystals, and the temperature was 85 ° C. and the relative humidity (R
H) held at 20% for 2 hours, then held at 35 ° C. and relative humidity (RH) 75% for 5 hours for aging to perform β-maltose having a crystallinity of 69.0% and a water content of 6.4%. The water-containing crystal-containing powder was obtained in a yield of 89% in terms of anhydride with respect to the raw material corn starch. This powder contains glucose 6.0%, maltotriose 0.8%, and oligosaccharide 3.1% having a glucose polymerization degree of 4 or more together with maltose 90.1% in terms of an anhydride, and maltose isomerization It contained 9.9% of α-anomer in maltose as a body and was excellent in solubility in an aqueous medium. Moreover,
It is a powder that exhibits almost no hygroscopicity even when stored at 25 ° C. and a relative humidity (RH) of 75.2%, has excellent storage stability, has good flowability, and is easy to handle. In addition, as a result of measuring the particle size distribution of the present powder, it was found that particles containing agglomerated fine particles in particles, and particles of 150 μm or more and 300 μm or less
% Was included.

The powder is also excellent in solubility in an aqueous medium, as a sweetener, a taste improver, a quality improver, a stabilizer, a discoloration inhibitor, a filler, an excipient, a binder and the like. Therefore, for example, not only a liquid substance containing a large amount of water or water, but also a paste-like substance, a semi-solid substance or a solid substance,
Including, food and drink, favorite food, feed, food, cosmetics,
It can be advantageously used for various compositions such as pharmaceuticals. Furthermore, as it is, or as needed, it is mixed with a filler, an excipient, a binder and the like to give granules, spheres, short rods, plates, cubes,
It is also optional to use it by forming it into various shapes such as tablets.

[0071]

[Example A-4-a] <Preparation of aqueous solution containing maltose>
Commercially available bacterial liquefied α-amylase (trade name “Spitase H” in a suspension of 1 part by weight of corn starch and 2 parts by weight of water.
S ”, sold by Nagase & Co., Ltd.) was heated to 90 ° C., gelatinized by heating and immediately heated to 130 ° C. to stop the enzyme reaction, and a DE4.3 liquefied liquid was obtained. 55 of this starch liquefaction liquid
50 units of starch debranching enzyme (isoamylase prepared by culturing Pseudomonas bacteria, sold by Hayashibara Biochemical Laboratories Co., Ltd.) after being rapidly cooled to ℃, β-amylase derived from soybean (trade name “# 1500”) 10 units of Nagase Sangyo Co., Ltd. were also added and saccharification was carried out for 40 hours while maintaining the pH at 5.0 to obtain a saccharified solution having a maltose content of 74.1% based on solids. According to a conventional method, this was decolorized by treatment with activated carbon, desalted by treatment with an ion exchange resin, purified, and concentrated under reduced pressure to obtain a maltose-containing aqueous solution having a sugar concentration of 45%, which was used as a fractionation raw material.

The fractionation resin used for the fractionation was an alkali metal type strongly acidic cation exchange resin (sold by Organo Corporation, trade name "Amberlite XT-1007 (Na ⁺ type)", crosslinking degree 6%). Use a stainless steel column with an inner diameter of 5.4 cm filled with a water suspension and connect the two columns so that the aqueous sugar solution flows in series to make the total length of the resin layer 1
It was set to 0 m.

While maintaining the temperature in the column at 55 ° C., 5 v / v% of the starting sugar aqueous solution was added to the resin.
Fractionation is carried out by flowing warm water at 5 ° C with SV0.3, and the maltotriose-rich fraction is separated and removed to have a high maltose content and a high maltose content including oligos and the like. Fractions were collected. Then, according to the usual method,
The product was decolorized by treatment with activated carbon, desalted by treatment with an ion exchange resin, purified, and concentrated under reduced pressure to obtain a maltose-containing aqueous solution. The sugar composition of the maltose-containing aqueous solution was glucose 9.8%, maltose 87.4%, maltotriose 1.0%, and maltotetraose 1.8% or more.

[0074]

[Example A-4-b] <Preparation of β-maltose hydrous crystal-containing powder> The maltose-containing aqueous solution obtained in Example A-4-a was concentrated to a water content of 20% and then transferred to an auxiliary crystallizer to seed crystals. As a result, 1% of β-maltose hydrated crystal was added, and the temperature of the musket was gradually lowered to 32 ° C. with slow stirring to partially crystallize β-maltose hydrated crystal over 16 hours. The crystallization rate was 39%. Since the muskite after the completion of the auxiliary crystal has a high viscosity, it is heated by a high-pressure pump at the time of sending the liquid, and the crystallization rate is not reduced to about 45,000.
While lowering the viscosity to cp or less, it was sprayed in a spray dryer using a rotating disk. At this time, the temperature of the hot air for drying was 90 ° C., the blowing of the hot air was vertical downward co-current in the spray dryer, and the amount of air blown was such that the moisture content of the dry powder when taken out from the spray dryer was 9.5%. Adjusted to.

This powder was immediately mixed and contacted with 0.2% of anhydrous α-maltose crystals, and the temperature was 90 ° C. and the relative humidity (R
H) held at 20% for 3 hours and then at 30 ° C. and 80% relative humidity (RH) for 5 hours for aging to perform β-maltose having a crystallinity of 64.6% and a water content of 6.8%. A water-containing crystal-containing powder was obtained with a yield of 80% in terms of anhydride with respect to the raw material corn starch. This powder contains maltose 87.4%, glucose 9.8%, maltotriose 1.0%, and oligosaccharides 1.8% having a glucose polymerization degree of 4 or more, in addition to maltose isomerization. It contained 12.7% of α-anomer in maltose as a body and was excellent in solubility in an aqueous medium. Moreover, even when stored under the conditions of 25 ° C. and relative humidity (RH) of 75.2%, it exhibits almost no hygroscopicity, and has excellent heat retention stability,
The powder had good flowability and was easy to handle. Further, as a result of measuring the particle size distribution of the present powder, it was found that the particles contained powder in which fine particles were aggregated, and particles of 150 μm or more and 300 μm or less were included in 53%.

The powder is also excellent in solubility in an aqueous medium as a sweetener, a taste improver, a quality improver, a stabilizer, a discoloration inhibitor, a bulking agent, an excipient, a binder and the like. Therefore, for example, not only a liquid substance containing a large amount of water or water, but also a paste-like substance, a semi-solid substance or a solid substance,
Including, food and drink, favorite food, feed, food, cosmetics,
It can be advantageously used for various compositions such as pharmaceuticals. Furthermore, as it is, or as needed, it is mixed with a filler, an excipient, a binder and the like to give granules, spheres, short rods, plates, cubes,
It is also optional to use it by forming it into various shapes such as tablets.

[0077]

Example B-1 <Sweetener> 0.5 part by weight of the powder containing hydrous crystals of β-maltose obtained by the method of Example A-1-b, 0.5 part by weight of anhydrous sorbitol crystals, α-glycosyl stevioside ( Toyo Seito Sugar Co., Ltd. sells the registered trademark "αG Suite" 0.01 parts by weight and L-aspartyl-L-phenylalanine methyl ester (Ajinomoto Co. sells the registered trademark "Aspartame") 0.01 parts by weight. The mixture was mixed and subjected to a granule molding machine to obtain a granular sweetener. This product has excellent sweetness, has a sweetness about twice that of sucrose, and is substantially low in calories. This sweetener has excellent stability without decomposition of the high-intensity sweeteners mixed in it, and as a low-calorie sweetener, it is a low-calorie food and drink for obese people, diabetics, etc. whose calorie intake is restricted. It is suitable for sweetening things. Further, the present sweetener is suitable for sweetening foods and beverages that suppress tooth decay because it produces less acid due to cavities-inducing bacteria and less insoluble glucan.

[0078]

Example B-2 <Hard candy> 50 parts by weight of sucrose and 50 parts by weight of the powder containing the β-maltose hydrous crystals obtained by the method of Example A-2-b are dissolved in 100 parts by weight of water and mixed by heating. Then, the mixture was heated and concentrated under reduced pressure until the water content was less than 2%, and 0.6 part by weight of citric acid and an appropriate amount of lemon flavor and color were mixed and molded according to a conventional method to obtain a product. This product is a stable, high-quality hard candy with good crispness, color tone, taste and flavor, no sucrose crystallization, little hygroscopicity, and no sagging.

[0079]

[Example B-3] <Chewing gum> 3 parts by weight of a gum base are heated and melted to a softness, and 2 parts by weight of anhydrous crystalline maltitol (registered trademark "Mabit", sold by Hayashibara Shoji Co., Ltd.) and 2 parts by weight of xylitol. Part, Example A-3
2 parts by weight of the powder containing β-maltose hydrous crystals obtained by the method of -b, and 1 part by weight of hydrous crystalline trehalose (registered trademark "Treha", sold by Hayashibara Shoji Co., Ltd.) were further added, and an appropriate amount of flavor and colorant were added. Were mixed and kneaded by a roll according to a conventional method, molded and packaged to obtain a product. The product has a good texture, taste and flavor, and is suitable as a chewing gum with low caries and low calories.

[0080]

Example B-4 <Sugared condensed milk> 2 parts by weight of the powder containing the β-maltose hydrous crystals obtained by the method of Example A-4-b and 2 parts by weight of sucrose were dissolved in 100 parts by weight of raw milk, and a plate heater was used. The product was sterilized by heating in, then concentrated to a concentration of 70%, and aseptically canned to obtain a product. This product has a mild sweetness and good flavor, and can be advantageously used for seasoning fruits, coffee, cocoa, tea and the like.

[0081]

[Example B-5] <Lactic acid bacterium beverage> 175 parts by weight of skim milk powder, 60 parts by weight of β-maltose hydrous crystal-containing powder obtained by the method of Example A-2-b, and lactosucrose-rich powder (Hayashibara Co., Ltd.) Commercial sales, registered trademark "milk fruit oligo") 5
Dissolve 0 parts by weight of water in 1,150 parts by weight, and mix at 30 ° C at 65 ° C.
After sterilizing for minutes and cooling to 40 ° C, according to a conventional method,
30 parts by weight of a lactic acid bacterium starter was inoculated and cultured at 37 ° C. for 8 hours to obtain a lactic acid bacterium beverage. This product has a good flavor, contains oligosaccharides, and is suitable as a lactic acid bacterium beverage having not only a stable lactic acid bacterium-promoting effect but also a bifidobacteria growth-promoting action and an intestinal-regulating action.

[0082]

[Example B-6] <Powder juice> Example A- was used with respect to 33 parts by weight of orange juice powder produced by spray drying.
Powder 5 containing β-maltose hydrous crystals obtained by the method of 4-b
0 parts by weight, anhydrous crystalline maltitol (Hayashibara Shoji registered trademark "Mabit") 10 parts by weight, anhydrous citric acid 0.65 parts by weight, malic acid 0.1 parts by weight, ascorbic acid 2-glucoside crystal powder ( Hayashibara Shoji Co., Ltd.)
2 parts by weight, 0.1 part by weight of sodium citrate, pullulan (Hayashibara Shoji Co., Ltd., trade name "PF-20") 0.5
Part by weight and an appropriate amount of powdered fragrance are well mixed and stirred, pulverized into a fine powder, charged into a fluidized bed granulator, and exhausted at a temperature of 4
The temperature was set to 0 ° C., and an appropriate amount of a 70% aqueous solution in which the powder containing β-maltose hydrous crystals obtained by the method of Example-4-b was dissolved in water was sprayed as a binder, granulated for 30 minutes, weighed, and packaged. Got the product. This product contains about 30% fruit juice
It is a powdered juice. In addition, this product has no off-taste or off-flavor and has high commercial value as high-quality juice.

[0083]

[Example B-7] <Coffee drink> 100 parts by weight of roasted coffee beans were crushed and extracted with 1,000 parts by weight of hot water to obtain 860 parts by weight of an extract. This solution 450
Water containing 90 parts by weight of β-maltose hydrated crystal-containing powder obtained by the method of Example A-1-b and 4 parts by weight of water containing 4 parts by weight of baking soda.
00 parts by weight was added and mixed uniformly to prepare a neutral pH coffee beverage, which was then filled in a can according to a conventional method and heat-sterilized at 120 ° C. for 30 minutes to produce a canned coffee beverage. . This product is a high-quality coffee drink with good aroma and taste. Also, put this product in the vending machine,
Even after holding at 60 ° C. for 1 month, its good flavor was well maintained. In addition, this product is a high-quality coffee drink that has a good aroma and taste even if it is cooled and stored for summer.

[0084]

Example B-8 <Custard Cream> 100 parts by weight of corn starch, 50 parts by weight of β-maltose hydrous crystal-containing powder obtained by the method of Example A-2-b, hydrous crystal trehalose (Hayashibara Shoji Co., Ltd., Registered trademark "Treha") 6
Thoroughly mix 0 parts by weight, 40 parts by weight of sugar, and 1 part by weight of salt, add 280 parts by weight of chicken egg, stir, and gradually add 1,000 parts by weight of boiled milk, and further heat to stir. Then, when the cornstarch was completely gelatinized and the whole became semi-transparent, the heat was turned off, this was cooled, an appropriate amount of vanilla flavor was added, and the product was weighed, filled and packaged. This product is a high-quality custard cream with a smooth luster, a good flavor, and suppressed starch aging.

[0085]

Example B-9 <Uiro> 90 parts by weight of rice flour, 20 parts by weight of corn starch, and anhydrous crystalline maltitol (produced by Co., Ltd.)
Hayashibara Shoji, registered trademark "Mabit") 70 parts by weight, β-maltose hydrous crystal-containing powder containing 50 parts by weight obtained by the method of Example A-1-b, and pullulan (Hayashibara Shoji Co., Ltd., trade name " 4 parts by weight of PF-20 ″) were uniformly mixed to produce iuirojin. Uironin, an appropriate amount of matcha and water were kneaded, put in a container and steamed for 60 minutes to produce matcha uiro. This product has good shine, mouthfeel, and flavor. In addition, the aging of starch is suppressed, the shelf life is good, and it is also suitable as a low-calorie uiro.

[0086]

[Example B-10] <Fertilization> 4 parts by weight of rice cake powder was dissolved in 6 parts by weight of water, and the mixture was poured into a wooden frame covered with a wet cloth, steamed at 100 ° C for 20 minutes, and then applied. Example A-1
A β-maltose hydrous crystal-containing powder (2 parts by weight) obtained by the method (b) and sugar (2 parts by weight) were added, and the mixture was sufficiently kneaded and then molded to obtain a fertilizer. This product has a good flavor, and the aging of gelatinized sticky rice starch is suppressed, and the shelf life thereof can be greatly extended.

[0087]

[Example B-11] <Anne> To 10 parts by weight of the raw azuki bean,
According to a conventional method, water was added and boiled, then astringent, then drained and water-soluble impurities were removed to obtain about 21 parts by weight of red bean paste. 14 parts by weight of this raw bean paste, Example A-
Powder 3 containing β-maltose hydrous crystals obtained by the method 3-b
1 part by weight and 7 parts by weight of water were added and boiled, and a small amount of salad oil was added thereto and kneaded so as not to break the crushed bean paste to obtain about 35 parts by weight of bean paste. This product is color burned,
It is stable without water separation, feels good and has a good flavor, and is suitable as a confectionery material such as sweet bean paste, steamed bun, dumplings, buns, and frozen desserts.

[0088]

Example B-12 <Bread> 100 parts by weight of wheat flour, 2 parts by weight of yeast, 5 parts by weight of sugar, 5 parts by weight of powder containing β-maltose hydrous crystals obtained by the method of Example A-1-b, and inorganic food In a conventional manner, 0.1 part by weight was kneaded with water, the medium seeds were fermented at 26 ° C. for 2 hours, and then aged and baked for 30 minutes. This product is a high-quality bread with good hue and sudachi, moderate elasticity and mild sweetness.

[0089]

[Example B-13] <Bread> 100 parts by weight of rice flour (marketed by Gojojo Nutry Co., Ltd., trade name "Koujou Aoi"),
18 parts by weight of gluten (sold by Chiba Milling Co., Ltd., trade name "Glurich A"), 3 parts by weight of sugar, 4 parts by weight of hydrous crystalline trehalose (sales by Hayashibara Shoji, trade name "treha"), Example A-2 8 parts by weight of the powder containing β-maltose hydrous crystals obtained by the method of -b, 2 parts by weight of salt, 2.5 parts by weight of marine yeast (sold by Sankyo Foods Co., Ltd.), 10 parts by weight of fresh cream, 5 parts by weight of unsweetened condensed milk Part, shortening 4 parts by weight, water 8
5 parts by weight was put into a mixer, kneaded at 23 ° C. for 6 minutes at a low speed and 3 minutes at a medium speed, temporarily stopped, and then further kneaded at a medium speed for 4 minutes to prepare a dough. Then, this was fermented for 50 minutes as floor time. The dough is divided and rounded and molded, and after 20 minutes of bench time, 40 ° C,
Fermentation was performed in a proofer having a humidity of 80% for 50 minutes. After the fermentation, 4 in an oven at 230 ℃ on the upper heat and 200 ℃ on the lower heat
It was baked for 5 minutes to prepare a rice flour bread. This product has a large volume increase, swells plumply, and has a good color tone.
The cross section was nice and the taste was good. Furthermore, the texture of the bread after being left in the refrigerator (5 ° C.) for 1 week showed almost no change, no dryness due to curing was observed, and the storability was good.

[0090]

Example B-14 <Icing> 1.2 parts by weight of an emulsifier (sugar ester) was heated and mixed with 10 parts by weight of the powder containing the β-maltose hydrous crystals obtained by the method of Example A-2-b, and then, 107 parts by weight of water-containing crystalline trehalose (trade name “Treha”, sold by Hayashibara Shoji Co., Ltd.) was mixed, and 7.5 parts by weight of oil and fat was further mixed while maintaining at 45 ° C. to produce icing. This product contains trehalose microcrystals, has good moldability, is non-sticky, and is an icing with little change over time.

[0091]

[Example B-15] <Bonbon> 3 parts by weight of the powder containing the β-maltose hydrous crystal obtained by the method of Example A-3-b, trehalose hydrous crystal (registered trademark “Treha” by Hayashibara Shoji Co., Ltd.) 300 By weight, 115 parts by weight of water were mixed, heated to boil to Bx70, the product temperature was cooled to 80 ° C., 40 parts by weight of brandy were mixed, and then molded according to a conventional method to obtain a bonbon. This product is a high-quality bonbon that contains trehalose microcrystals, has a rich brandy flavor, and has a small daily change.

[0092]

[Example B-16] <Ham> 15 parts by weight of salt and 3 parts by weight of potassium nitrate are uniformly rubbed into 1,000 parts by weight of pork thigh meat, and the mixture is deposited in a cold room for 24 hours. This was added to a salting solution consisting of 500 parts by weight of water, 100 parts by weight of salt, 3 parts by weight of potassium nitrate, 40 parts by weight of powder containing β-maltose hydrous crystals obtained by the method of Example A-4-b, and spices in a cold room. It was immersed for a day, then washed with cold water, wrapped with a string, smoked, cooked, cooled and packaged according to a conventional method to obtain a product. This product is a high quality ham with good color and flavor.

[0093]

[Example B-17] <Tsukudani> 250 parts by weight of kelp cut with sand and acid-treated, 212 parts by weight of soy sauce, 318 parts by weight of amino acid solution, and β-obtained by the method of Example A-3-b While adding 35 parts by weight of maltose hydrous crystal-containing powder and 20 parts by weight of sugar, the mixture was further boiled by adding 12 parts by weight of sodium glutamate and 8 parts by weight of caramel to obtain kelp Tsukudani. This product is a low cariogenic Tsukudani. Moreover, not only the taste and aroma, but also the color and luster are appetizing.

[0094]

[Example B-18] <Bath agent> 10 parts by weight of powder containing β-maltose hydrous crystals obtained by the method of Example A-1-b was mixed with 1 part by weight of yuzu peel juice, A powder containing Yuzu skin extract was obtained. 5 parts by weight of this powder, 9 salt of roasted salt
0 parts by weight, hydrous crystalline trehalose (registered trademark "Treha" by Hayashibara Shoji Co., Ltd.) 2 parts by weight, silicic acid anhydride 1 part by weight and α-glucosyl hesperidin (Hayashibara Shoji Co., Ltd., trade name "αG hesperidin") 0.5 parts by weight and 2 parts by weight of ascorbic acid 2-glucoside crystal powder (available from Hayashibara Shoji Co., Ltd.) were mixed to produce a bath agent. This product has a rich yuzu scent and is suitable for bathing in water of 100 to 10,000.
It is a high-quality bath agent that can be used after diluting it by 0 times, and after bathing, the skin is moist and smooth and does not cool in hot water.

[0095]

[Example B-19] <Cosmetic cream> Polyoxyethylene glycol monostearate 2 parts by weight, self-emulsifying glyceryl monostearate 5 parts by weight, Example A-1-
5 parts by weight of β-maltose hydrous crystal-containing powder obtained by the method of b, 1 part by weight of α-glucosyl rutin (Hayashibara sales, registered trademark “αG rutin”), ascorbic acid 2-glucoside crystal powder (Hayashibara, Inc.) 1 part by weight, 1 part by weight of liquid paraffin, 10 parts by weight of glyceryl trioctanoate and an appropriate amount of a preservative are dissolved by heating according to a conventional method, and 2 parts by weight of L-lactic acid, 5 parts by weight of 1,3-butylene glycol and 66 parts by weight of purified water was added, the mixture was homogenized and emulsified, and an appropriate amount of perfume was further added and mixed with stirring to produce a cosmetic cream. The product has antioxidant properties and high stability, and can be advantageously used as a high-quality sunscreen, skin-refining agent, skin-whitening agent and the like.

[0096]

[Example B-20] <Toothpaste> Dibasic calcium phosphate 4
5 parts by weight, sodium lauryl sulfate 1.5 parts by weight, glycerin 25 parts by weight, poxyethylene sorbitan laurate 0.5 part by weight, β-obtained by the method of Example A-2-b
A toothpaste was obtained by mixing 10 parts by weight of the powder containing maltose-containing crystals, 0.02 part by weight of saccharin and 0.05 part by weight of preservative with 13 parts by weight of water. This product has improved taste and sensation without deteriorating the detergency of the surfactant and has a good feeling after use.

[0097]

[Example B-21] <Solid preparation for liquid food> Example A-3
Powder 10 containing β-maltose hydrous crystals obtained by the method b)
0 parts by weight, trehalose hydrous crystals 200 parts by weight, maltotetraose high content powder 200 parts by weight, powder egg yolk 270
Parts by weight, 209 parts by weight skim milk powder, sodium chloride 4.4
Parts by weight, potassium chloride 1.8 parts by weight, magnesium sulfate 4 parts by weight, thiamine 0.01 parts by weight, sodium ascorbate 0.1 parts by weight, vitamin E acetate 0.6 parts by weight and nicotinic acid amide 0.04 parts by weight. Was prepared, and 25 g of the composition was filled in a moisture-proof laminated pouch and heat-sealed to obtain a product. This product is a liquid food with an excellent intestinal action, in which an appropriate sweetness is added by β-maltose hydrous crystal-containing powder and trehalose hydrous crystal. One bag is dissolved in about 150 to 300 ml of water to give a liquid food, which is used orally or by a tube-like method for nasal cavity, stomach, intestine, etc. and can be advantageously used for energy supply to the living body.

[0098]

Example B-22 <Tablet> Aspirin (50 parts by weight) was thoroughly mixed with β-maltose hydrous crystal-containing powder obtained by the method of Example A-4-b (14 parts by weight) and corn starch (4 parts by weight), and 4. Tableted by tableting machine according to the method
A tablet of 25 mm and one tablet of 680 mg was produced. This product is
It utilizes the shapeability of β-maltose hydrous crystal-containing powder, has no hygroscopicity, has sufficient physical strength, and is extremely good in disintegration in water.

[0099]

[Example B-23] <Sugar-coated tablet> An uncoated tablet having a weight of 150 mg was used as a core, and 40 parts by weight of powder containing β-maltose hydrous crystals obtained by the method of Example A-4-b was added to pullulan (produced by Co., Ltd.). Hayashibara Shoji, product name "PF-20") 2 parts by weight, water 30 parts by weight, talc 25 parts by weight and titanium oxide 3
The tablet weight is about 230m using the parting solution.
Sugar coating until g, then 65 parts by weight of the same powder containing hydrous crystals of β-maltose, 1 part by weight of pullulan (Hayashibara Shoji Co., Ltd., trade name "PF-20") and 34 parts by weight of water. It was sugar-coated with the liquid and further polished with a wax liquid to obtain a sugar-coated tablet having an excellent glossy appearance. This product has excellent impact resistance and maintains high quality for a long time.

[0100]

As is clear from the above description, the present invention is pulverized by the spraying method, contains 86% or more and less than 93% of maltose and 2% or more of glucose in terms of anhydride, and has a crystallinity of The β-maltose hydrous crystal-containing powder containing 62% or more and less than 72% contains 7% or more and less than 14% of the α-anomer in maltose as a maltose isomer,
It has excellent solubility in aqueous media and excellent storage stability.
It is a powder with good flowability and easy handling. Further, these β-maltose hydrous crystal-containing powders contain sugars other than maltose such as glucose, maltotriose and oligosaccharides having a glucose polymerization degree of 4 or more in a relatively large amount of 7% or more and less than 14%. Nevertheless, it is easy to manufacture by a spraying method, continuous, can be manufactured in a short time, and has a high powder yield, so that it is easy to reduce the cost.

Therefore, the present invention is utilized not only in the starch sugar manufacturing industry but also in the starch sugar manufacturing industry, since the powder containing β-maltose hydrous crystals excellent in solubility in an aqueous medium can be easily manufactured at low cost. It is convenient for the person on the side because improvement of workability can be expected, and the industrial significance to the relevant industries such as food and drink, cosmetics, and pharmaceutical manufacturing industry is extremely great.

[Brief description of drawings]

FIG. 1 Maltose content is 86.2% in terms of anhydride.
The powder X-ray diffraction pattern of the β-maltose hydrous crystal-containing powder having a crystallinity of 62.1%.

[Fig. 2] Maltose content is 91.3% in terms of anhydride.
The powder X-ray diffraction pattern of the powder containing β-maltose hydrous crystals having a crystallinity of 70.8%.

[Fig. 3] Maltose content is 95.0% in terms of anhydride.
Powder X-ray diffraction pattern of purified maltose (registered trademark "San Marto S") having a crystallinity of 74.5%.

FIG. 4 Maltose content is 99.6% in terms of anhydride.
Powder X-ray diffraction pattern of a reagent β-maltose hydrous crystal (trade name "maltose HHH") having a crystallinity of 82.6%.

FIG. 5: Maltose content is 98.5% in terms of anhydride.
Powder X-ray diffraction pattern of anhydrous α-maltose crystal (registered trademark “Fine Tose”) having a crystallinity of 76.3%.

─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. ⁷ Identification code FI A61K 7/00 A61K 7/00 K N 7/16 7/16 7/50 7/50 9/20 9/20 9/28 9 / 28 47/34 47/34 47/36 47/36 47/42 47/42 47/44 47/44 // C13F 1/02 C13F 1/02 (58) Fields surveyed (Int.Cl. ⁷ , DB Name) C13K 1/00-11/00 C13F 1/00-5/00

Claims (13)

(57) [Claims] 1. A powder produced by a spraying method, converted into an anhydride,
Maltose containing 86 w / w% or more and less than 93 w / w% and 2 w / w% or more of glucose to be a maltose isomer
And the content of α-anomer in maltose is 7 w / w% or more 1
Β-maltose hydrous crystal-containing powder having a crystallinity of 62% or more and less than 72% at less than 4 w / w% . 2. Further, as another carbohydrates, beta-maltose hydrated crystal-containing powder of claim 1 containing a maltotriose and glucose polymerization degree of 4 or more oligosaccharides. 3. The β-maltose according to claim 1 or 2, which contains 60 w / w% or more of powder having a particle size of more than 106 μm, preferably 40 w / w% or more of a powder of more than 150 μm and 300 μm or less in a particle size distribution test. Powder containing hydrous crystals. 4. A powder having a particle size of more than 150 μm and not more than 300 μm contains an aggregate composed of a plurality of fine particles.
The β-maltose hydrous crystal-containing powder described. 5. The β-maltose hydrous crystal-containing powder according to any one of claims 1 to 4, which is excellent in solubility in an aqueous medium. 6. Maltose 86 w / w% in terms of anhydride
An aqueous solution containing at least 93 w / w% and at least 2 w / w% glucose is used as a mass kit in which β-maltose hydrous crystals are crystallized, and then powdered by a spraying method,
Further, by keeping the atmosphere at a high temperature at a relative humidity (RH) of less than 40% to obtain a powder having a high content of α-anomer in maltose, and then keeping the atmosphere at a low temperature exceeding a relative humidity (RH) of 70% , the maltose contained in maltose α-anomer content of 7 w / w %
It is reduced to less than 14 w / w % as described above, and a powder having a crystallinity of 62% or more and less than 72% is collected to contain the β-maltose hydrous crystal according to any one of claims 1 to 5. Powder manufacturing method. 7. The β-maltose hydrous crystal according to claim 6, wherein, when spraying the musket, the musket is heated in a range not substantially lowering the crystallization rate to reduce the viscosity and spraying. A method for producing a contained powder. Upon 8. kept hot atmosphere at a relative humidity (RH) less than 40%, according to claim 6 or <br/> characterized by causing the powder obtained in the spray method are contacted with α- anhydrous maltose crystals 7. The method for producing a powder containing β-maltose hydrous crystals according to 7. 9. β- according to any one of claims 1 to 5.
A composition comprising a maltose hydrous crystal-containing powder or a β-maltose hydrous crystal-containing powder obtained by the production method according to claim 6 dissolved in an aqueous medium. 10. The composition according to claim 9, wherein the aqueous medium is water, a liquid containing a large amount of water or a paste, a semi-solid, or a solid. 11. An aqueous medium containing one or two selected from sugars, starch, lipids, proteins, polyphenols and emulsifiers.
The composition according to claim 9 or 10, containing one or more species. 12. The composition according to claim 9, which is a food or drink, a cosmetic or a pharmaceutical product. 13. A food, a cosmetic, or a pharmaceutical product is a sweetener, a hard candy, a chewing gum, a sweetened condensed milk,
Lactic acid bacteria drink, powdered juice, coffee drink, custard cream, uiro, fertilizer, bean paste, bread, icing,
The composition according to claim 12, which is a bonbon, ham, boiled radish, bath preparation, cosmetic cream, toothpaste, solid preparation for liquid food, tablet or dragee.