JP3326059B2 - Skin cosmetics - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an excellent skin cosmetic which has no sticky feeling at the time of use, has a high moisturizing effect, and can maintain the effect for a long time.

[0002]

2. Description of the Related Art Moisture retention in skin is an indispensable factor for keeping skin healthy, and many cosmetics, pharmaceuticals and the like for moisturizing are commercially available. Also, researches on substances related to moisturizing have been actively conducted, and various moisturizing agents have been provided. Among them, glycerin, propylene glycol and water-soluble polyhydric alcohols represented by sorbitol as water-retaining moisturizers have been used for water retention,
It is widely used in cosmetics and pharmaceuticals because of its excellent hygroscopicity.

[0003] However, although the conventional humectants have a certain effect, they have a strong sticky feeling at the time of use and are not preferred in terms of sensuality. In addition, there has been a demand for a skin cosmetic that can maintain a higher moisturizing effect by maintaining the moisturizing effect only for a short time after application.

[0004]

SUMMARY OF THE INVENTION An object of the present invention is to provide a moisturizing agent for skin cosmetics which has no sticky feeling during use and maintains a high moisturizing effect for a long time.

[0005]

Means for Solving the Problems To achieve the above object, the skin cosmetic of the present invention has the following constitution. That is, the present invention is a skin cosmetic comprising at least one kind of α, α-trehalose-6,6 ′ difatty acid ester and at least one kind of water-soluble polyhydric alcohol. .

[0006]

Embodiments of the present invention will be described below in detail.

The α, α-trehalose used in the present invention
The 6,6 ′ difatty acid ester forms a liquid crystal when mixed with water or water and a polyhydric alcohol. Since the liquid crystal has a characteristic that an amphiphilic substance associates and arranges in a high order and can retain a large amount of water in its structure, the skin cosmetic of the present invention shows excellent moisturizing properties.

[0008] α, α-trehalose in the present invention
6,6 ′ difatty acid ester is a known substance and has been reported to have an antitumor effect (Japanese Patent Publication No. 62-5911).
No. 7). However, it was not known that this substance shows a moisturizing effect when used in combination with a polyhydric alcohol. In addition, this substance can be obtained by using a usual method for producing a sucrose fatty acid ester, and a straight or branched chain, saturated or unsaturated fatty acid can be used as a constituent fatty acid. The number 8 to 22 are preferred, and more preferably 10 to 18 (USP2
89990).

The amount of the α, α-trehalose-6,6 ′ difatty acid ester was determined to be a range in which the object of the present invention is to avoid stickiness during use and to maintain a high moisturizing effect for a long time. It is preferably 0.0001 to 20% by weight (hereinafter simply abbreviated as%), more preferably 0.001 to 10%, based on the total amount of the skin cosmetic of the present invention.

The water-soluble polyhydric alcohol used in the present invention is a compound having two or more hydroxyl groups in a molecule, and specific examples thereof include glycerin, diglycerin, polyglycerin, propylene glycol, dipropylene glycol,
Compounds such as butylene glycol, polyethylene glycol, sucrose, fructose, maltitol, xylitol, sorbitol, maltose, and maltotriose are listed, and one or more of these are used.

The mixing ratio of α, α-trehalose-6,6 ′ difatty acid ester and water-soluble polyhydric alcohol used in the present invention is effective for obtaining the effects of the present invention and for efficiently forming the liquid crystal. , Approximately 1: 1000 to 1: 1
Is preferred.

The skin cosmetic of the present invention contains, in addition to the above components, pigments, fragrances, preservatives, surfactants, alcohols, liquid paraffin, pigments, antioxidants, water-soluble polymers and the like. It can be appropriately blended within the range achieved.

[0013] The skin cosmetic of the present invention comprises a cream, an emulsion,
Formulations such as lotions and foundations can be made, and an appropriate amount thereof is applied to the skin of the face or body parts.

[0014]

EXAMPLES Hereinafter, the present invention will be described in detail with reference to Examples, Comparative Examples, and Test Examples, but the present invention is not limited thereto.
In addition, (1) liquid crystal formation test, (2) moisture retention test,
(3) The method of the sensory test is as follows.

(1) Liquid Crystal Forming Test At room temperature, a small amount of a sample was placed on a slide glass, and observed under a crossed Nicols under a polarizing microscope structure image to determine the presence or absence of liquid crystal formation.

(2) Moisturizing test After washing the face, the sample was applied, and after 0, 2, 4, 8, and 24 hours,
Electric conductivity by skin electric resistance meter (unit: micromho)
Was measured and the moisture retention was evaluated.

(3) Sensory test A sensory test was conducted by 20 female panelists, and the items of "moist feeling", "stickiness" and "persistence of moist feeling" were "appropriately moist" and "sticky". No "," The moist feeling is maintained ".

Test Example 1 and Comparative Example 1 were prepared according to a conventional method with the following formulation, and (1) a liquid crystal forming property test was performed.

Test Example 1 • α, α-trehalose-6,6 ′ dilaurate 10.0 (%) • Glycerin 10.0 • Purified water 80.0

Comparative Example 1 Glycerin 10.0 (%) Purified water 90.0

As a result of the liquid crystal forming property test, Test Example 1 showed a structure image peculiar to the liquid crystal structure, whereas Comparative Example 1 did not show any. Thus, α, α-trehalose-6, It is clear that 6 'dilaurate forms liquid crystals.

Test Example 2 and Comparative Example 2 were prepared in the usual manner according to the following formulation, and (2) a moisture retention test and (3) a sensory test were carried out.

Test Example 2-Ethanol 10.0 (%)-α, α-trehalose-6,6 'dilaurate 0.1-Glycerin 20.0-Purified water 69.9

Comparative Example 2-Ethanol 10.0 (%)-Glycerin 20.0-Purified water 70.0

FIG. 1 shows the results of the moisture retention test of Test Example 2 and Comparative Example 2, and Table 1 shows the results of the sensory test.

[0026]

[Table 1]

As shown in FIG. 1 and Table 1, Test Example 2 was superior to Comparative Example 2 in both moisture retention (see FIG. 1) and sensory characteristics, and was particularly excellent in that "no stickiness". . From the above results, α, α-trehalose-6,6
'It is clear that the difatty acid ester suppresses the stickiness of the water-soluble polyhydric alcohol and maintains the moisturizing effect.

Hereinafter, Examples 1 to 3 and Comparative Examples 3 and 4 were prepared in the usual manner according to the following formulation, and (3) a sensory test was carried out.

Example 1 Emulsion (1) Sorbitan sesquioleate 0.15 (%) polyoxyethylene (20EO) 0.5 sorbitan monooleate cetanol 1.0 petrolatum 2.0 squalane 5.0 butyl paraben 0.1 (2) α, α-trehalose-6,6 ′ 0.9 dimyristate glycerin 10.0 dipropylene glycol 8.0 methyl paraben 0.1 xanthan gum 0.2 sodium cetyl sulfate 0.3 purified water 71 .75

Example 2 Foundation (1) Cetanol 3.0 (%) Vaseline 5.0 Glyceryl monostearate 2.5 Stearic acid 3.0 Butylparaben 2.0 Polyoxyethylene (10EO) 1.0 Stearyl ether (2) sorbitol 10.0 1,3-butylene glycol 12.0 α, α-trehalose-6,6 ′ 0.5 dipalmitic acid ester Compound powder 15.0 Sodium cetyl sulfate 1.2 Purified water 44. 8

Example 3 Cream (1) Cetanol 2.5 (%) Glyceryl monostearate 2.0 Stearic acid 2.5 Lanolin 2.0 Squalane 5.0 Liquid paraffin 5.0 Butylparaben 0.2 (2) Maltitol 16.0 α, α-trehalose-6,6 ′ 0.05 distearate carboxyvinyl polymer 0.2 purified water 64.55

Comparative Example 3 Emulsion (1) Cetanol 1.0 (%) Vaseline 2.0 Squalane 5.0 Butylparaben 0.1 (2) Sodium cetyl sulfate 0.5 Dipropylene glycol 18.0 Methylparaben 0.1 Xanthan gum 0.2 Purified water 73.1

Comparative Example 4 Emulsion (1) Cetanol 1.0 (%) Vaseline 2.0 Squalane 5.0 Butylparaben 0.1 (2) Sodium cetyl sulfate 0.5 α, α-trehalose-6,6′0 .5 Distearate methyl paraben 0.1 Xanthan gum 0.2 Purified water 90.6

Table 2 shows Examples 1-3 and Comparative Examples 3-4.
5 shows the results of a sensory test.

[0035]

[Table 2]

As shown in Table 2, the emulsions, foundations and creams of the present invention were all excellent in all respects as compared with the comparative examples. In particular, it was extremely superior to the comparative example in that "there was no stickiness". On the other hand, Comparative Example 3 had a "moist feeling" but was inferior in sustainability, was hardly said to have a sufficient moisturizing effect, and had a strong "sticky feeling", which was not preferable in terms of sensory characteristics. Comparative Example 4 had no "sticky feeling" but was inferior to "moist feeling" and "persistence of moist feeling".

[0037]

As described above, the skin cosmetic of the present invention is excellent in moisturizing effect, suppresses "stickiness" due to polyhydric alcohol in the sense of function, and is excellent in that those effects last for a long time. It is clear.

[Brief description of the drawings]

FIG. 1 is a graph showing the results of a moisture retention test of Test Example 2 and Comparative Example 2.

[Explanation of symbols]

 ■: Test example 2 ●: Comparative example 2

Continuation of front page (56) References JP-A-9-131078 (JP, A) JP-A-8-53339 (JP, A) JP-A-8-53326 (JP, A) JP-A-6-239717 (JP) JP-A-5-168893 (JP, A) JP-A-5-137994 (JP, A) JP-A-5-126688 (JP, A) JP-A-62-191236 (JP, A) 60-258195 (JP, A) JP-A-60-183032 (JP, A) JP-A-60-114335 (JP, A) Table 9-503499 (JP, A) (58) Fields investigated (Int. A61K ^7/ 00-7/50 JICST file (JOIS)

Claims (1)

(57) [Claims] 1. A skin cosmetic comprising at least one kind of α, α-trehalose-6,6 ′ difatty acid ester and at least one kind of water-soluble polyhydric alcohol.