JP3263119B2 - Release paper for patches - Google Patents
Release paper for patchesInfo
- Publication number
- JP3263119B2 JP3263119B2 JP11078192A JP11078192A JP3263119B2 JP 3263119 B2 JP3263119 B2 JP 3263119B2 JP 11078192 A JP11078192 A JP 11078192A JP 11078192 A JP11078192 A JP 11078192A JP 3263119 B2 JP3263119 B2 JP 3263119B2
- Authority
- JP
- Japan
- Prior art keywords
- release paper
- film
- patch
- desiccant
- plaster layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicinal Preparation (AREA)
- Laminated Bodies (AREA)
Description
【０００１】[0001]
【産業上の利用分野】本発明は、例えばテープ剤に代表
されるような貼付剤の膏体層に貼付けられ、使用時にお
いて剥離される貼付剤用の剥離紙に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a release paper for a patch which is applied to a plaster layer of a patch such as a tape and peeled off at the time of use.
【０００２】[0002]
【従来の技術】テープ剤、パップ剤プラスターなどの貼
付剤は、経口投与に比して、薬物の肝臓での代謝による
分離を防ぐことができる点や、胃腸障害を起こしにくい
点、あるいは長時間の効果を期待できる点などにおいて
有利である。従って、貼付剤に広い範囲の薬剤が利用さ
れつつあるが、多くの薬剤は水分の存在で不安定である
場合が多い。そこで、最近では上記の貼付剤の利点を活
用すべく、水分に不安定な薬剤を含有する貼付剤の安定
性を確保するために、アルミ袋等に貼付剤と共に乾燥剤
を封入する方法が採られている。2. Description of the Related Art Patches such as tapes, cataplasms and plasters can prevent separation of drugs due to metabolism in the liver, are less likely to cause gastrointestinal disorders, or have a longer duration than oral administration. This is advantageous in that the effect can be expected. Therefore, a wide range of drugs are being used in patches, but many drugs are often unstable in the presence of moisture. Therefore, recently, in order to utilize the advantages of the above-mentioned patch, in order to ensure the stability of the patch containing a drug unstable to water, a method of enclosing a desiccant together with the patch in an aluminum bag has been adopted. Have been.
【０００３】[0003]
【発明が解決しようとする課題】しかし、このように乾
燥剤を一緒に封入する方法では、防湿性が充分でない場
合が多く、薬剤の安定性の維持が確実でない。また、乾
燥剤を一緒に封入するのでは包装形態としてもかさばる
など運搬上好ましくなく、また、いちいち乾燥剤を投入
するために製作工程も繁雑になるという欠点が生じてい
た。そして、脱臭剤や脱酸素剤などについても、乾燥剤
と同様の課題があった。However, in such a method in which a desiccant is enclosed together, the moisture-proof property is often insufficient, and it is not reliable to maintain the stability of the drug. Further, if the desiccant is enclosed together, it is not preferable in terms of transportation, such as a bulky package, and the production process becomes complicated since the desiccant is charged each time. Then, the same problem as that of the desiccant has been encountered for the deodorant and the oxygen scavenger.
【０００４】[0004]
【課題を解決するための手段】従って、本発明は貼付剤
の確実な防湿性や、防臭性、酸化防止効果を確保するこ
とによって、水に不安定な薬剤の安定性を確実にするこ
とはもとより、薬剤の分解を低減させて品質維持を図る
と共に、包装形態としてもかさばることなく、製作や運
搬に便利な貼付剤用の剥離紙を得ることを目的とする。
かかる目的を達成するために、貼付剤の膏体層に貼付け
られ、使用時において剥離される貼付剤用の剥離紙であ
って、水通過性を有する台紙と剥離性のあるフィルムと
の間に乾燥剤と活性炭とを粘着剤を用いて封入してサン
ドイッチ状に構成した。また、紙、織布または不織布の
フィルムに乾燥剤を含浸せしめ、或いはその繊維の隙間
に乾燥剤を封入せしめると共に、フィルムの膏体層に接
する側の面にシリコンコートを施して構成した。さら
に、プラスチックフィルム、硬質ゴムまたはパルプのフ
ィルムに乾燥剤を封入せしめ、フィルムの膏体層に接す
る側の面にシリコンコートを施して構成した。そして、
アルミニウムフィルムの膏体層に接する側の面にシリコ
ンコートを施すと共に、その反対の面にプラスチックフ
ィルムに練り込ませた乾燥剤または活性炭がーティング
されるよう構成した。SUMMARY OF THE INVENTION Accordingly, the present invention is to secure the stability of water-unstable drugs by ensuring the reliable moisture-proofing, deodorizing and antioxidant effects of the patch. In addition, it is an object of the present invention to obtain a release paper for a patch which is easy to manufacture and transport without reducing the decomposition of the drug and maintaining the quality, and not bulky as a packaging form.
In order to achieve such an object, a release paper for a patch which is stuck to the plaster layer of the patch and peeled off at the time of use, between a backing sheet having water permeability and a peelable film. A desiccant and activated carbon were sealed using an adhesive to form a sandwich. Further, a film of paper, woven fabric or non-woven fabric is impregnated with a desiccant, or a desiccant is sealed in the gaps between the fibers, and the film is coated with a silicon coat on the surface in contact with the plaster layer. Further, a desiccant was sealed in a plastic film, hard rubber or pulp film, and a silicone coat was applied to a surface of the film in contact with the plaster layer. And
A silicon coat was applied to the surface of the aluminum film in contact with the plaster layer, and a desiccant or activated carbon kneaded into a plastic film was coated on the opposite surface.
【０００５】[0005]
【作用】剥離紙に保持した乾燥剤等により防湿性、防臭
性、酸化防止性を確保して、製薬剤の安定性を確保す
る。[Function] The desiccant and the like held on the release paper ensure the moisture-proof property, the deodorant property, and the antioxidant property, thereby ensuring the stability of the chemical preparation.
【０００６】[0006]
【実施例】以下、本発明の実施例について説明する。図
１に示されるように、貼付剤１に剥離紙２が貼付けてあ
る。貼付剤１は、例えば布や不織布等の適当な支持体３
の内面に膏体層４を形成した構成である。膏体層４は基
剤、粘着剤等の薬剤や膏体を含んでいる。剥離紙２は、
水通過性のある台紙５と剥離性のあるフィルム６との間
に乾燥剤７と活性炭８を合成のり等の粘着剤を用いて封
入してサンドイッチ状に構成したものである。剥離性の
あるフィルム６は、通常剥離紙として用いられている全
ての材質が使用でき、例えば、紙、グラシン紙、織布、
不織布などの他、ポリエチレン（ＰＥ）、ポリエチレン
テレフタレート（ＰＥＴ）などのプラスチックフィル
ム、硬質ゴム、或はアルミニウムなどの剥離性のあるフ
ィルムなどを使用する。特に、膏体層４に接する側の面
にシリコンコートを施してあると、剥離性が良く、好都
合である。 台紙５は、例えば、紙、グラシン紙、織
布、不織布などの他、ポリエチレン（ＰＥ）、ポリエチ
レンテレフタレート（ＰＥＴ）などのプラスチックフィ
ルム等の水透過性のある包材が使用される。 また、乾
燥剤７には、例えばシリカゲルや塩化カルシウム、シリ
カアルミナゲルなどを粉粒状や薄い板状にしたものを用
いることができる。Embodiments of the present invention will be described below. As shown in FIG. 1, a release paper 2 is attached to a patch 1. The patch 1 is made of a suitable support 3 such as cloth or non-woven fabric.
Is a configuration in which a plaster layer 4 is formed on the inner surface. The plaster layer 4 contains a medicine such as a base and an adhesive, and a plaster. The release paper 2
A desiccant 7 and activated carbon 8 are sealed between a water-permeable backing sheet 5 and a releasable film 6 using an adhesive such as synthetic glue to form a sandwich. As the film 6 having releasability, all materials usually used as release paper can be used. For example, paper, glassine paper, woven fabric,
In addition to a nonwoven fabric, a plastic film such as polyethylene (PE) or polyethylene terephthalate (PET), a peelable film such as hard rubber, or aluminum is used. In particular, if a silicon coat is applied to the surface in contact with the plaster layer 4, the peelability is good and it is convenient. For the mount 5, for example, a water-permeable packaging material such as a plastic film such as polyethylene (PE) and polyethylene terephthalate (PET) is used in addition to paper, glassine paper, woven fabric, and nonwoven fabric. As the desiccant 7, for example, silica gel, calcium chloride, silica-alumina gel, or the like in the form of powder or a thin plate can be used.
【０００７】図２は、紙、織布、不織布などからなるフ
ィルム６に乾燥剤７を直接含浸せしめるか、或はその繊
維の隙間に封入せしめると共に、フィルム６の膏体層４
に接する側の面にシリコンコート９を施した剥離紙２の
実施例を示している。図３は、ポリエチレン（ＰＥ）、
ポリエチレンテレフタレート（ＰＥＴ）などのプラスチ
ックフィルム、硬質ゴム、或はパルプなどからなるフィ
ルム６に乾燥剤７を封入せしめ、フィルム６の膏体層４
に接する側の面にシリコンコート９を施した剥離紙２の
実施例を示している。図４は、アルミニウムフィルム１
０の膏体層４に接する側の面にシリコンコート９を施す
と共に、その反対の面にポリエチレン等に練り込ませた
乾燥剤７や活性炭８をコーティング（塗布）した剥離紙
２の実施例を示している。そして、以上のような乾燥剤
７や活性炭８の代わりに、或はこれらと一緒に、例えば
活性酸化鉄等の脱酸素剤を用いることもできる。何れに
しても、乾燥剤、活性炭、もしくは脱酸素剤の何れか一
つ、或は任意の組合せで混合、併用して封入したり、含
浸、塗布することにより、それらを剥離紙２に保持せし
めたものである。FIG. 2 shows that a film 6 made of paper, woven fabric, non-woven fabric or the like is directly impregnated with a desiccant 7 or is filled in the interstices of the fibers.
2 shows an embodiment of the release paper 2 in which a silicon coat 9 is applied to the surface in contact with the release paper 2. FIG. 3 shows polyethylene (PE),
A desiccant 7 is encapsulated in a film 6 made of a plastic film such as polyethylene terephthalate (PET), hard rubber, or pulp, and a plaster layer 4 of the film 6 is formed.
2 shows an embodiment of the release paper 2 in which a silicon coat 9 is applied to the surface in contact with the release paper 2. FIG. 4 shows an aluminum film 1
In the embodiment of the release paper 2, a silicone coat 9 is applied to the surface in contact with the plaster layer 4, and a desiccant 7 or activated carbon 8 kneaded in polyethylene or the like is coated (applied) on the opposite surface. Is shown. Instead of the drying agent 7 and the activated carbon 8 as described above, or together with these, a deoxidizing agent such as activated iron oxide can be used. In any case, any one of a desiccant, activated carbon, or a deoxidizer, or any combination thereof is mixed, used in combination, encapsulated, impregnated, or applied to hold them on the release paper 2. It is a thing.
【０００８】そして、貼付剤１の膏体層４と剥離紙２の
フィルム６を合わせるように貼付け、使用時において
は、剥離紙２を剥離し、露出した貼付剤１の膏体層４を
人体皮膚に貼付けて使用する。しかして、以上のような
ものにあっては、乾燥剤等を剥離紙に保持せしめたこと
によって、膏体層の薬剤と常に近い一定の部位でその作
用を発揮させることができるため、従来にない極めて優
れた防湿、或は防臭、防酸化効果をあげることができ、
特に、乾燥剤と活性炭の併用による薬剤の分解物量の低
減効果は著しく優れており、これにより、膏体層４に水
に不安定な薬剤を含めることができるといった利点があ
る。Then, the adhesive layer 4 of the adhesive patch 1 and the film 6 of the release paper 2 are adhered together so that the adhesive layer 4 is peeled off in use. Use by attaching to the skin. However, in the above, since the desiccant or the like is held on the release paper, the effect can be exerted at a constant site always close to the medicine of the plaster layer. Not very good moisture-proof, or deodorant, anti-oxidant effect,
In particular, the combined use of a desiccant and activated carbon has a remarkably excellent effect of reducing the amount of decomposed products of the drug, which has the advantage that the plaster layer 4 can contain a drug that is unstable in water.
【０００９】[0009]
【発明の効果】本発明によれば、乾燥剤を剥離紙に保持
させることにより、薬剤の安定性の向上を図ることがで
きる。そして、包装形態としてもかさばることなく、小
型包装が可能となるので、製作や運搬に極めて便利であ
る。また、乾燥剤の他に活性炭を剥離紙に保持させる
と、脱臭効果酸化防止効果も図ることができる。更に、
乾燥剤に活性炭を組み合わせて保持せしめると、薬剤の
分解を一層低減することができ、製剤安定性を高めると
いった利点がある。According to the present invention, the stability of the drug can be improved by holding the desiccant on the release paper. And since a small packaging is attained without being bulky also in a packaging form, it is very convenient for manufacture and transportation. When activated carbon is held on the release paper in addition to the desiccant, the deodorizing effect and the antioxidant effect can be achieved. Furthermore,
When activated carbon is held in combination with the desiccant, there is an advantage that the decomposition of the drug can be further reduced and the stability of the preparation is enhanced.
【図１】剥離紙を貼付けた貼付剤の断面図FIG. 1 is a cross-sectional view of a patch to which a release paper is attached.
【図２】他の実施例の貼付剤の断面図FIG. 2 is a cross-sectional view of a patch of another embodiment.
【図３】他の実施例の貼付剤の断面図FIG. 3 is a cross-sectional view of a patch of another embodiment.
【図４】他の実施例の貼付剤の断面図FIG. 4 is a cross-sectional view of a patch of another embodiment.
１ 貼付剤 ２ 剥離紙 ３ 支持体 ４ 膏体層 ５ 台紙 ６ フィルム ７ 乾燥剤 ８ 活性炭 ９ シリコンコート １０ アルミニウムフィルム REFERENCE SIGNS LIST 1 adhesive 2 release paper 3 support 4 plaster layer 5 mount 6 film 7 desiccant 8 activated carbon 9 silicon coat 10 aluminum film
───────────────────────────────────────────────────── フロントページの続き (56)参考文献 特開 昭63−185919（ＪＰ，Ａ) 特開 昭55−106160（ＪＰ，Ａ) 特開 平５−25039（ＪＰ，Ａ) 特開 平２−305572（ＪＰ，Ａ) 特開 平２−92629（ＪＰ，Ａ) 実開 平１−83027（ＪＰ，Ｕ) 実開 昭61−7535（ＪＰ，Ｕ) 特公 昭63−26004（ＪＰ，Ｂ１) (58)調査した分野(Int.Cl.7，ＤＢ名) A61K 9/70 A61F 13/00 - 13/02 B32B 27/00 ──────────────────────────────────────────────────続 き Continuation of the front page (56) References JP-A-63-185919 (JP, A) JP-A-55-106160 (JP, A) JP-A-5-25039 (JP, A) JP-A-2- 305572 (JP, A) JP-A-2-92629 (JP, A) JP-A-1-83027 (JP, U) JP-A-61-7535 (JP, U) JP-B-63-2604 (JP, B1) (58) Field surveyed (Int.Cl. 7 , DB name) A61K 9/70 A61F 13/00-13/02 B32B 27/00
Claims (4)
おいて剥離される貼付剤用の剥離紙であって、水通過性Release paper for patches that is peeled off in
を有する台紙と剥離性のあるフィルムとの間に乾燥剤とA desiccant between the backing and the release film
活性炭とを粘着剤を用いて封入してサンドイッチ状に構Activated carbon is sealed with an adhesive to form a sandwich.
成されていることを特徴とする貼付剤用剥離紙。Release paper for a patch characterized by being formed.
おいて剥離される貼付剤用の剥離紙であって、紙、織布Release paper for patches that are peeled off in the
または不織布のフィルムに乾燥剤を含浸せしめ、或いはOr impregnating a desiccant into a nonwoven film, or
その繊維の隙間に乾燥剤を封入せしめると共に、フィルFill the gap between the fibers with a desiccant and fill
ムの膏体層に接する側の面にシリコンコートを施したこSilicone coating on the side that contacts the plaster layer
とを特徴とする貼付剤用剥離紙。And a release paper for patches.
おいて剥離される貼付剤用の剥離紙であって、プラスチRelease paper for a patch that is peeled off at
ックフィルム、硬質ゴムまたはパルプのフィルムに乾燥Dry to black film, hard rubber or pulp film
剤を封入せしめ、フィルムの膏体層に接する側の面にシAnd seal it on the side of the film that is in contact with the plaster layer.
リコンコートを施したことを特徴とする貼付剤用剥離Peeling off patch characterized by having been recon-coated
紙。paper.
おいて剥離される貼付剤用の剥離紙であって、アルミニRelease paper for patches that are peeled off
ウムフィルムの膏体層に接する側の面にシリコンコートSilicon film on the side of the film that contacts the plaster layer
を施すと共に、その反対の面にプラスチックフィルムにAnd apply a plastic film on the opposite side
練り込ませた乾燥剤または活性炭がコーティングされてKneaded desiccant or activated carbon coated
いることを特徴とする貼付剤用剥離紙。Release paper for patches.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11078192A JP3263119B2 (en) | 1992-04-03 | 1992-04-03 | Release paper for patches |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11078192A JP3263119B2 (en) | 1992-04-03 | 1992-04-03 | Release paper for patches |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0656653A JPH0656653A (en) | 1994-03-01 |
| JP3263119B2 true JP3263119B2 (en) | 2002-03-04 |
Family
ID=14544457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11078192A Expired - Fee Related JP3263119B2 (en) | 1992-04-03 | 1992-04-03 | Release paper for patches |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3263119B2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070158227A1 (en) * | 2004-01-30 | 2007-07-12 | Satoshi Amano | Plaster enclosing packaging bag |
| JP2008260780A (en) * | 2008-06-09 | 2008-10-30 | Nitto Denko Corp | Sheet-type adhesive material |
| CN105816271A (en) * | 2015-01-05 | 2016-08-03 | 陕西远光高科技有限公司 | Medical functional silica gel dressing material |
| CN106539644A (en) * | 2017-01-03 | 2017-03-29 | 上海孩子国科教设备有限公司 | Sticking structure |
-
1992
- 1992-04-03 JP JP11078192A patent/JP3263119B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0656653A (en) | 1994-03-01 |
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