JP3231221B2 - Guide wire - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a guidewire having a function of guiding a catheter or the like to a target site in a living body and a function of collecting biological information.

[0002]

2. Description of the Related Art There is known a catheter in which a sensor or a transducer is provided at a distal end portion and through which a temperature and a potential in a living body can be detected at an outer end of a body.
In this catheter, a connector for relaying a detection signal output from a sensor or the like and transmitted via a conducting wire to an external device such as a monitor device is provided at an outer end (base end side). And this connector was much larger than the diameter of the catheter for reasons such as easy handling.

[0003] By the way, PTCA (Percutaneous Tra
In catheters used for nsluminal coronary angioplasty (percutaneous coronary angioplasty), etc., a guidewire is incorporated into the catheter prior to insertion of the catheter into the blood vessel, and the guidewire tip is inserted together with the catheter so that the tip of the guidewire precedes. It has been practiced to guide a part to the vicinity of a target part, a vascular stenosis part.

[0004] Here, PTCA catheters have a wide variety of variations depending on the size of the stenosis site, the blood vessel diameter, and the like, and in some cases, it is necessary to replace the catheter after inserting the blood vessel. In addition, even when a plurality of indwelling devices called stents for securing an inner diameter in a blood vessel are installed, the catheter may be withdrawn and inserted several times from the blood vessel.

[0005] Therefore, it has been studied to provide a guide wire, which can be shared in most cases, with a biological information collecting function, rather than providing a catheter with the aforementioned biological information collecting function.

However, as described above, it is necessary to install a connector at the outer end of the guide wire, and since the size of the connector is far larger than the diameter of the guide wire, the catheter is inserted from the outer end of the guide wire. Cannot be inserted or removed, thereby impairing the original function of the guidewire.

Therefore, when inserting the catheter,
Once withdrawing the guide wire having the biological information collection function from the blood vessel, re-insert the normal guide wire into the same blood vessel,
Since it is necessary to insert the catheter into the target site along the guide wire, the burden on the patient increases, the risk of complications such as vascular perforation accompanying the replacement of the guide wire increases, and the operation time and labor are increased. Cause an increase.

[0008]

SUMMARY OF THE INVENTION An object of the present invention is to provide a guidewire having a function of collecting biological information without impairing the original function of the guidewire.

[0009]

This and other objects are achieved by the present invention which is defined below as (1) to (8).

(1) A guide wire having a biological information collecting function, a wire main body made of a flexible solid wire, and an information detecting section provided at a distal end of the wire main body and detecting biological information. , Provided on the surface of the wire body,
A signal transmission member for transmitting information obtained by the information detection unit as an electric signal; and a terminal provided at a base end of the wire main body, surrounding a periphery of the wire main body, and being electrically connected to the signal transmission member. The terminal is provided such that the outer diameter of the proximal end of the guide wire does not exceed the outer diameter of the intermediate portion in the longitudinal direction of the guide wire, and the outer diameter is substantially constant from the proximal end to the intermediate portion. A guide wire configured to allow a catheter for a blood vessel to be easily inserted from the base end portion of the guide wire.

(2) The guide wire according to (1), wherein the signal transmission member includes a plurality of conductors, and a plurality of the terminals are provided corresponding to the respective conductors.

(3) The conductor has an insulating coating layer,
The guide wire according to the above (2), wherein the terminal is formed by removing a part of the insulating coating layer.

(4) The guide wire according to (2) or (3), wherein the conductive wire is spirally wound around an outer peripheral portion of the wire main body.

(5) The guide wire according to the above (2), wherein the terminal is connected to the conductive wire, and is formed of a ring-shaped conductive member surrounding the outer periphery of the wire main body.

(6) The guide wire according to any one of (2) to (5), wherein the terminals are provided at predetermined intervals along a longitudinal direction of the wire main body.

(7) The guide wire according to any one of (1) to (6), wherein the wire main body is made of a superelastic alloy.

[0017]

(8) The guide wire according to any one of (1) to (7), wherein a base end of the guide wire has a structure connectable to a connector having a contact member that contacts the terminal. .

[0019]

The background of the use of the guide wire having the biological information collecting function will be described. The treatment of coronary artery stenosis due to arteriosclerosis, which causes ischemic heart disease, is changing from the conventional mainstream surgical AC bypass operation to the above-mentioned minimally invasive treatment by PTCA operation.

When performing PTCA, X-ray angiography using a contrast agent is performed, and a dilation operation of a stenosis site is performed using a balloon catheter. At this time, the blood flow in the coronary artery is interrupted by the expansion of the balloon, and the myocardium is temporarily in an ischemic state. If this ischemia continues for a long time, it may lead to acute myocardial infarction.

For monitoring the ischemic level, the ST elevation of the electrocardiogram is usually observed, but the observation of the ST elevation by the intracardiac electrocardiogram in the coronary artery reflects myocardial ischemia more accurately. Therefore, when performing the PTCA operation, it is preferable to directly monitor the intracoronary electrocardiogram.

For these reasons, a guide wire having a function of detecting and collecting biological information such as intracardiac potential is extremely useful as a guide wire for inserting a PTCA catheter or the like. In addition, in the PTCA operation, the guide wire is inserted percutaneously from, for example, the femoral artery, and reaches the coronary artery through a long way while selecting a branch of a complicated blood vessel. Is more preferred.

A guide wire according to the present invention includes an information detecting section provided at a distal end for detecting biological information, a signal transmitting member for transmitting information obtained by the information detecting section as an electric signal, and a guide end at a proximal end. It is provided with a terminal that conducts with the provided signal transmission member, whereby biological information can be collected from outside the body, and the outer diameter of the proximal end of the guide wire is smaller than the outer diameter of the middle part in the longitudinal direction of the guide wire. Since the terminals are provided so as not to exceed, the original function of the guidewire, that is, the function of inserting the catheter from the proximal end side of the guidewire and guiding the catheter to the target site is not impaired.

Such a guide wire according to the present invention has a PT
Even when used for other than CA surgery, the same action and effect are exhibited.

[0025]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, a guide wire according to the present invention will be described in detail based on a preferred embodiment shown in the accompanying drawings.

FIG. 1 is an overall external view of the case where the guidewire of the present invention is applied to an intracardiac potential collection guidewire functioning as a coronary potential measurement lead, and FIG. 2 is a view of the guidewire shown in FIG. FIG. 3 is an enlarged perspective view showing a configuration of a base end portion of the guide wire shown in FIG. 1, and FIG. 4 is an equivalent circuit of a potential detection system of the guide wire shown in FIG. FIG. 5 is a side view showing a state in which a connector is attached to the base end of the guide wire.

As shown in FIG. 1, the guide wire 1A of the present invention has a wire main body (core wire) 2 which mainly forms the guide wire 1A. And guide wire 1A
Is composed of a distal end portion 21, an intermediate portion 22, and a proximal end portion 23 along its longitudinal direction.

The wire body 2 is a flexible wire material, and its constituent materials are not particularly limited, and various plastics and various metals can be used, but it is preferable that the wire main body 2 is made of a superelastic alloy. . Thereby, a guide wire excellent in torque transmission and kink resistance (bending) can be obtained without increasing the diameter of the guide wire.

Here, the superelastic alloy is generally called a shape memory alloy, and refers to an alloy that exhibits superelasticity at a use temperature.
Superelasticity refers to the property of recovering almost the original shape even when deformed (bent, stretched, compressed) to the area where ordinary metal plastically deforms at the use temperature, that is, at least the living body temperature (around 37 ° C.). . Preferred compositions of the superelastic alloy include a Ti-Ni alloy of 49 to 58 atomic% Ni, 3
8.5-41.5% by weight Zn-Cu-Zn alloy, 1-1
0 wt% X of Cu-Zn-X alloy (X is Be, Si,
At least one of Sn, Al, and Ga), 36 to 3
A superelastic body such as a Ni-Al alloy of 8 atomic% Al may be used. Of these, particularly preferred is the Ti-Ni
Alloy.

An electrode group (information detector) 3 composed of a plurality of electrodes 31 for collecting intracardiac potential (biological information) is provided at the distal end 21 of the wire main body 2. The electrodes 31 are arranged at predetermined intervals (preferably at equal intervals) along the longitudinal direction of the wire main body 2.

In this case, each electrode 31 is formed of the same metal ring as the terminal 51 at the base portion 23 described later.
The corresponding conductor 41 is electrically connected, for example, by welding. In addition, a coating layer or an adhesive layer is provided on the outer peripheral portion of the wire main body 2 between the adjacent electrodes 31 so that each conductive wire 41 is brought into close contact with the wire main body 2. Thereby, the outer surface of the coating layer or the adhesive layer and the outer peripheral surface of the electrode 31 constitute a substantially continuous surface, and the insertion of the guidewire 1A into the blood vessel can be performed easily and smoothly.

As shown in FIG. 2, the distal end portion 21 of the wire main body 2 is tapered according to characteristics such as contact resistance and bending resistance, and its outer diameter gradually decreases toward the distal end. ing. By forming the taper 211 at the distal end portion 21 in this manner, when the guide wire 1A is inserted into the blood vessel from the distal end portion 21 side and reaches a target site (such as a coronary artery), the guide wire 1A may be bent or branched. It can flexibly cope with a complicated blood vessel shape, and can easily insert and withdraw a guide wire.

A plurality of terminals 5 for extracting the potential detected by each of the electrodes 31 are provided at the base end 23 of the wire body 2.
1 is provided. Then, as shown in FIG. 4, each terminal 51 and the corresponding electrode 31 are electrically connected to each other by a conductor 41 which is a signal transmission member. In the case of this embodiment, for example, it has twelve electrodes 31, twelve terminals 51, and twelve conductive wires 41 connecting these.

As shown in FIG. 3, each conductive wire 41 extends over substantially the entire length of the wire
It is installed almost in parallel. Each terminal 51 includes a metal ring (ring-shaped conductive member) 52 surrounding the wire main body 2 and each conductive wire 41. These metal rings 52 are arranged at predetermined intervals (preferably at equal intervals) along the longitudinal direction of the wire body 2,
The corresponding conductor 41 is electrically connected, for example, by welding.

The metal ring 52 may be formed by fitting a ring-shaped member to the wire body 2 or by forming a thin metal film on the outer periphery of the wire body 2 by, for example, plating, vapor deposition, sputtering, or the like. In addition, metal ring 5
Examples of the metal constituting No. 2 include noble metals such as gold and platinum or alloys thereof, stainless steel, copper, aluminum,
Titanium or an alloy thereof is given.

The terminal 5 made of such a metal ring 52
1, the base end portion 23 of the guide wire 1A
, Electrical signals can be extracted from all directions on the outer periphery. Further, by selecting the width of the metal ring 52, the surface area of the terminal 51 can be appropriately set.

Although not shown, the metal ring 5
Each of the wires 4 is provided on the outer peripheral portion of the wire body 2 except for the mounting portion of the wire 2.
There is provided a coating layer or an adhesive layer for bringing 1 into close contact with the wire main body 2. As a result, the outer surface of the coating layer or the adhesive layer and the outer peripheral surface of the metal ring 52 constitute a substantially continuous surface, and the outer diameter of the guide wire 1A is
To the intermediate portion 22. Therefore, a catheter such as a PTCA catheter and a guiding catheter can be easily inserted from the proximal end portion 23 of the guide wire 1A.

The proximal end 23 of such a guide wire 1A
A connector 6 for extracting a signal detected by the electrode group 3 and transmitted through the conducting wire 41 and relaying the signal to an external device (not shown) such as an electrocardiograph is detachably mounted.

FIG. 5 shows a state where the connector 6 is attached to the base end 23 of the guide wire 1A. Connector 6
Has a terminal group 62 including a plurality of contact members 63 symmetrically arranged via a guide wire 1A.

The contact member 63 is made of a metal material having a hemispherical tip. The contact member 63 is supported by the support member 64 so as to be movable (expandable and contractible) in the radial direction of the guide wire 1A. It is urged toward the guide wire 1A by the stored coil spring 65. Each contact member 63 is arranged at a position where each terminal 51 comes into contact with the corresponding contact member 63 in a state where the base end of the guide wire 1 </ b> A is in contact with the inner wall 67 at the distal end of the shell 61.

Thus, when the connector 6 is mounted on the base end portion 23, each terminal 51 is sandwiched by the opposing contact members 63, and reliable electric contact between the terminals 51 and the contact members 63 is obtained.

The signal extracted from the contact member 63 is transmitted to a monitor such as an electrocardiograph via a conductor 66 connected to the coil spring 65. In the guide wire 1 </ b> A, the wire main body 2 may be formed of a hollow member, and each conductive wire 41 may be housed in the hollow portion of the wire main body 2.
In this case, in the distal end portion 21 and the proximal end portion 23, each conductive wire 41 penetrates the wall of the wire main body 2 from the inside,
Connected to electrode 31 and terminal 51, respectively.

FIG. 6 is a partially enlarged perspective view showing another embodiment of the guide wire according to the present invention, and FIG. 7 is a partially enlarged perspective view showing a configuration example of a lead wire used for the guide wire shown in FIG. The guide wire 1B shown in FIG. 6 is used for the same purpose as the guide wire 1A. The guide wire 1 </ b> B has a plurality of (12 in this embodiment) conductive wires 42 spirally wound around an outer peripheral portion of the same wire main body 2 as described above. That is, in this embodiment,
Twelve conductive wires 42 are arranged in parallel, and are wound around 12 wires in close contact with the outer periphery of the wire main body 2. With such a configuration, the number of signal lines can be increased without impairing the flexibility of the guide wire 1B.

As shown in FIG. 7, the conducting wire 42 has a clad structure, and includes a central carbon steel wire 43, a copper foil layer 44 covering the outer periphery thereof, a gold plating layer 45 covering the outer periphery thereof, and An insulating layer 46 made of a resin such as polyester, which covers the outer periphery, is used. Copper foil layer 44
Has a function of lowering the impedance of the conducting wire 42.

The conducting wire 42 having such a configuration hardly affects the mechanical properties of the guide wire 1B and impairs the properties of the guide wire 1B exhibited by the wire body 2 made of a superelastic alloy or the like. There is no. In addition, by using a clad material for the conductive wire 42 as a winding,
There is an advantage that breakage when winding the conductive wire 42 around the wire main body 2 is prevented, and that the impedance can be reduced to about the same level as when a normal copper wire is used. In addition, the conducting wire 42 used for the guide wire 1B is
It goes without saying that the present invention is not limited to the configuration shown in FIG.

As described above, the twelve conductive wires 42 wound around the wire main body 2 with the twelve wires are covered with the insulating layer 46, and therefore each of the twelve independent signal transmission lines of the intracardiac potential is provided. Act as

Further, as shown in FIG.
In the base end portion 23, in a state where the twelve conductive wires 42 are wound around the wire main body 2, the insulating layer 46 of a part (position where the terminal 53 is desired to be formed) of each of the conductive wires 42 is peeled off for approximately one round. Then, the gold plating layer 45 inside is exposed. The exposed portions (shown by oblique lines in FIG. 6) are used as signal extracting terminals 53 and 54. The terminal 53 in FIG. 6 is an exposed portion of the gold plating layer of the first conductive wire 42, the terminal 54 is an exposed portion of the gold plated layer of the second conductive wire 42. A terminal is formed by the exposed portion of the layer.

As described above, the terminals 53 and the like formed by peeling off the insulating layer 46 are arranged at predetermined intervals (preferably at equal intervals) along the longitudinal direction of the wire main body 2. In order to increase the area of the terminal, for example, a ring-shaped conductive member such as the metal ring 52 may be attached to the exposed portion of the gold plating layer.

At the base end 23 of the guide wire 1, the terminals 53 and the like are formed by peeling off the insulating layer 46 of the conductor 42, so that the outer diameter of the base end 23 is
Of the guide wire 1B
A catheter such as a PTCA catheter and a guiding catheter can be easily inserted from the base end portion 23, and the connector 6 can be easily and reliably mounted as described above.

FIGS. 8 and 9 are views showing a use state when the guide wire 1A of the present invention is used for PTCA operation. 8 and 9, reference numeral 100 indicates an aortic arch, reference numeral 101 indicates a right coronary artery of the heart, and reference numeral 102.
Denotes a right coronary artery opening, and reference numeral 103 denotes a vascular stenosis.
Reference numeral 104 denotes a guiding catheter for securely guiding the guidewire 1A from the femoral artery to the right coronary artery 101, and reference numeral 105 denotes a balloon catheter for expanding a stenosis having a balloon 106 which can be expanded and contracted at the distal end. .

As shown in FIG. 8, the distal end portion 21 of the guide wire 1A is projected from the distal end of the guiding catheter 104, and the right coronary artery 101 is inserted through the right coronary artery opening 102.
Insert inside. Further, the guide wire 1A is advanced, and the distal end portion 21 stops at a position beyond the blood vessel stenosis portion 103. Thereby, a passage for the balloon catheter 105 is secured.

Next, as shown in FIG.
Balloon catheter 1 inserted from the base end 23 side of A
05 is protruded from the distal end of the guiding catheter 104, further advanced along the guide wire 1 </ b> A, inserted into the right coronary artery 101 through the right coronary artery opening 102, and the balloon 106 is positioned at the position of the vascular stenosis 103. Stop when you reach it.

Next, a balloon inflation fluid is injected from the proximal end side of the balloon catheter 105, and the balloon 106 is inflated.
To expand the blood vessel stenosis part 103. As a result, the blood flow in the right coronary artery 101 is cut off, and the myocardium temporarily enters an ischemic state.

In order to grasp the ischemic state, as shown in FIG. 9, the electrode 31 of the distal end portion 21 of the guide wire 1A protruding from the distal end of the balloon catheter 105 by a predetermined length.
Detects the cardiac potential in the coronary artery by
The electrocardiogram in the coronary artery can be monitored by an electrocardiograph (not shown) via the connector 6 connected to each terminal 51 of the base end portion 23 of the device. The guide wire 1B can be used similarly.

FIG. 10 is an overall external view and a partially enlarged perspective view showing another embodiment of the guide wire of the present invention. The guide wire 1C shown in FIG.
An ultrasonic transducer 71 for acoustically observing a blood vessel wall or the like is provided on the distal end portion 21 as an information detecting unit for detecting biological information. The ultrasonic transducer 71 includes a distal end portion 21, an intermediate portion 22, and a proximal end portion 23. It is a guide wire.

The wire main body 2 of the guide wire 1C has a hollow outer shaft 24 and an inner shaft 2 inserted through the outer shaft 24 and rotatable with respect to the outer shaft 24.
5 is comprised.

At the tip portion 21, the inner shaft 25
An ultrasonic transducer 71 for transmitting and receiving an ultrasonic wave is fixed to the tip of the. This ultrasonic transducer 7
1 is connected to one end of a conductor 72 serving as a signal transmission member, and the conductor 72 is housed in a hollow portion formed in the inner shaft 25.

On the other hand, at the base end 23, a pair of terminals 73 made of the same metal ring as described above are provided on the outer peripheral surface of the inner shaft 25 at predetermined intervals in the longitudinal direction of the wire main body 2. . Conductive wires 72 are connected to these terminals 73, respectively. The signal output from the ultrasonic transducer 71 is transmitted to the proximal end side via the conducting wire 72 and is extracted from the terminal 73. There may be a plurality of ultrasonic transducers, in which case the conductor 7
2 and the terminal 73
Double the number.

The outer diameter of the metal ring forming the terminal 73 is preferably smaller than the outer diameter of the outer shaft 24. In such a base end portion 23, when collecting biological information,
A connector (not shown) provided with a contact member that comes into contact with both terminals 73 is mounted.

A rod-shaped torque transmitting member 74 is fitted into the proximal end of the inner shaft 25. On the outer periphery of the torque transmitting member 74, irregularities 75 extending in the longitudinal direction are formed, and the frictional force between the irregularities 75 and the inner surface of the inner shaft 25 causes the rotational force of the torque transmitting member 74 to move inward. The power is transmitted to the shaft 25. And the outer shaft 24
With the inner shaft 2 at the proximal end 23
When a rotational force is applied to 5, the rotational force is transmitted to the distal end portion 21 and the ultrasonic transducer 71 rotates. By synchronizing this rotation with the transmission / reception cycle of ultrasonic waves,
A radial image of a blood vessel can be obtained.

Even in such a guide wire 1C,
Similarly to the above, the outer diameter of the proximal end portion 23 does not exceed the outer diameter of the intermediate portion 22.
From 3, it is possible to easily insert a catheter such as a PTCA catheter and a guiding catheter,
Attachment of the connector to the base end 23 can also be performed easily and reliably.

The guide wire 1C is connected to the aforementioned PTCA
When used for surgery, after diagnosing the degree of progress of the vascular stenosis portion 103 of the coronary artery, or after performing dilation treatment of the vascular stenosis portion 103 with a balloon catheter 105 or the like, the state of the blood vessel is displayed as an image. This is very useful for diagnosing whether or not dilatation treatment with the balloon catheter 105 is possible and for predicting restenosis.

In the above-mentioned guide wires 1A to 1C, the diameter is not particularly limited. When the guide wire is used for inserting a PTCA catheter, the diameter (average) is as follows.
It is preferably about 0.25 to 0.65 mm, and 0.3
More preferably, it is about 6 to 0.45 mm.

Although the guide wire of the present invention has been described based on the illustrated embodiments, the present invention is not limited to these embodiments. For example, the information detection unit that detects biological information is not limited to the above-described one, and may be, for example, a thermocouple, a temperature sensor such as a thermistor, a pressure sensor that measures blood pressure, and the like.

In the present invention, the wire body may be made of a solid member or a hollow member, and may be made of the above-described superelastic alloy, piano wire, or the like.
In addition to metal materials such as stainless steel and tungsten, those made of various resin materials such as polyimide, polyester, polyolefin (polypropylene, polyethylene), fluororesin, and polyurethane may be used. Further, the wire main body may be formed of a laminate in which a plurality of layers having different materials or physical characteristics are laminated. Furthermore, in order to adjust the flexibility of the wire main body, for example, a spiral slit or groove can be formed on the whole or a part (for example, a tip portion) of the wire main body.

[0066]

As described above, according to the guidewire of the present invention, the entire function of the guidewire is removed, particularly when the catheter needs to be replaced after the approach to the target site is completed. Without removing the catheter from the proximal end side without any trouble, it is possible to collect biological information such as potential, temperature, pressure, ultrasonic image, etc. without impairing the function of replacing the catheter while leaving the guide wire. .

For this reason, when the guide wire of the present invention is used in, for example, PTCA, it is not necessary to replace the guide wire, so that the burden on the patient is greatly reduced and the operation time (diagnosis time) is reduced. In addition, it is possible to reduce the trouble of the operation, and it is possible to avoid the risk of complications such as vascular perforation due to the replacement of the guide wire.

Further, when the signal transmission member is composed of a plurality of conductors and a plurality of terminals are provided corresponding to each conductor, more information can be collected. Also,
When the terminal is formed by peeling off a part of the insulating coating layer of the conductor, the terminal can be easily formed without increasing the outer diameter of the base end.

When the conductor is spirally wound around the outer periphery of the wire main body, a guide wire which does not impair flexibility can be obtained. In particular, when the wire main body is made of a superelastic alloy, the effect is remarkable.

Further, when the terminal is formed of a ring-shaped conductive member surrounding the outer periphery of the wire main body, there is no direction for extracting a signal when the connector is mounted or the like.
Also, the surface area of the terminal can be set appropriately.

When the terminals are provided at predetermined intervals along the longitudinal direction of the wire main body, it becomes easy to extract a signal by mounting a connector or the like. Also,
When the signal transmission member is inserted into the hollow portion of the wire main body, detachment or disconnection of the signal transmission member from the wire main body is less likely to occur.

When the information detecting section is installed rotatably with respect to at least the outer peripheral portion of the wire main body, multi-directional biological information can be collected at the guide wire insertion site by rotating the information detecting section. Can be.

[Brief description of the drawings]

FIG. 1 is an overall external view of a case where a guidewire of the present invention is applied to an intracardiac potential collection guidewire functioning as a coronary artery potential measurement lead.

FIG. 2 is an enlarged perspective view showing a configuration of a distal end portion of the guide wire shown in FIG.

FIG. 3 is an enlarged perspective view showing a configuration of a base end portion of the guide wire shown in FIG.

FIG. 4 is a circuit diagram showing an equivalent circuit of a potential detection system of the guide wire shown in FIG.

FIG. 5 is a side view showing a state where a connector is attached to a base end portion of the guide wire.

FIG. 6 is a partially enlarged perspective view showing another embodiment of the guide wire of the present invention.

FIG. 7 is a partially enlarged perspective view showing a configuration example of a conductive wire used for the guide wire shown in FIG. 6;

FIG. 8 is a schematic diagram for explaining an example of using the guide wire of the present invention.

FIG. 9 is a schematic diagram for explaining an example of using the guide wire of the present invention.

FIG. 10 is an overall external view and a partially enlarged perspective view showing another embodiment of the guide wire of the present invention.

[Explanation of symbols]

 1A to 1C Guide wire 2 Wire body 21 Tip 22 Intermediate portion 23 Base end 24 Outer shaft 25 Inner shaft 3 Electrode group 31 Electrode 41, 42 Conductive wire 43 Carbon steel wire 44 Copper foil layer 45 Gold plated layer 46 Insulating layer 5 Terminal group REFERENCE SIGNS LIST 51 terminal 52 metal ring 53, 54 terminal 6 connector 61 shell 62 terminal group 63 contact member 64 support member 65 coil spring 66 conductive wire 67 tip inner wall 71 ultrasonic transducer 72 conductive wire 73 terminal 74 rotational force transmitting member 75 unevenness 100 aortic arch 101 right crown shape Artery 102 right coronary artery opening 103 vascular stenosis 104 guiding catheter 105 balloon catheter 106 balloon

Claims (8)

(57) [Claims] 1. A guide wire having a biological information collecting function, comprising: a wire main body made of a flexible solid wire; an information detecting unit provided at a distal end of the wire main body for detecting biological information; A signal transmission member provided on the surface of the wire main body and transmitting the information obtained by the information detection unit as an electric signal; and a signal transmission member provided on the base end of the wire main body, surrounding the outer periphery of the wire main body, and transmitting the signal. A terminal that is electrically connected to the member, the terminal is provided such that an outer diameter of a base end of the guide wire does not exceed an outer diameter of a middle portion in a longitudinal direction of the guide wire, and the terminal is provided from the base end. A guide wire having a substantially constant outer diameter toward an intermediate portion so that a catheter for a blood vessel can be easily inserted from the base end portion of the guide wire. 2. The guide wire according to claim 1, wherein the signal transmission member includes a plurality of conductors, and a plurality of the terminals are provided corresponding to the respective conductors. 3. The guide wire according to claim 2, wherein the conductor has an insulating coating layer, and the terminal is formed by peeling a part of the insulating coating layer. 4. The guide wire according to claim 2, wherein the conductive wire is spirally wound around an outer peripheral portion of the wire main body. 5. The guide wire according to claim 2, wherein the terminal is connected to the conductor and is formed of a ring-shaped conductive member surrounding an outer periphery of the wire main body. 6. The guide wire according to claim 2, wherein the terminals are provided at predetermined intervals along a longitudinal direction of the wire main body. 7. The guidewire according to claim 1, wherein the wire main body is made of a superelastic alloy. 8. The guidewire according to claim 1, wherein the base end of the guidewire is configured to be connectable to a connector having a contact member that contacts the terminal.