JP3185344B2 - In-vivo probe for nuclear magnetic resonance equipment - Google Patents
In-vivo probe for nuclear magnetic resonance equipmentInfo
- Publication number
- JP3185344B2 JP3185344B2 JP10089592A JP10089592A JP3185344B2 JP 3185344 B2 JP3185344 B2 JP 3185344B2 JP 10089592 A JP10089592 A JP 10089592A JP 10089592 A JP10089592 A JP 10089592A JP 3185344 B2 JP3185344 B2 JP 3185344B2
- Authority
- JP
- Japan
- Prior art keywords
- magnetic resonance
- probe
- nuclear magnetic
- coil
- interest
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- Magnetic Resonance Imaging Apparatus (AREA)
Description
【０００１】[0001]
【産業上の利用分野】本発明は、被検体中の水素や燐等
からの核磁気共鳴（以下、ＮＭＲという）信号を測定
し、核の密度分布や緩和時間分布等を映像化するＮＭＲ
装置用プローブのうち、特に体腔内に挿入可能なＮＭＲ
装置用体腔内プローブに関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an NMR spectrometer which measures nuclear magnetic resonance (hereinafter referred to as "NMR") signals from hydrogen, phosphorus and the like in an object to visualize the density distribution and relaxation time distribution of nuclei.
NMR probe that can be inserted into body cavities especially among device probes
The present invention relates to an intracorporeal probe for a device.
【０００２】[0002]
【従来の技術】従来、ＮＭＲ装置では、被検体（例え
ば、人）の関心部位を取り巻く各種の頭部用コイルや腹
部用コイル，心臓等の動きの影響を受けにくい表面コイ
ル等を用い被検体の検査，撮像が行われてきた。2. Description of the Related Art Conventionally, an NMR apparatus uses various kinds of head coils and abdominal coils surrounding a site of interest of a subject (for example, a person), surface coils that are hardly affected by movement of the heart, and the like. Inspection and imaging have been performed.
【０００３】これらのコイルには、生体内の微小部分を
高感度高空間解像度で画像化することができないという
問題があった。[0003] These coils have a problem that a minute portion in a living body cannot be imaged with high sensitivity and high spatial resolution.
【０００４】これに対して、生体の胃，食道，腸等の体
腔内に小型コイルを挿入することにより高感度高空間解
像度で画像化するＮＭＲ装置用体腔内プローブが提案さ
れている。例えば、直腸挿入のＮＭＲ装置用体腔内プロ
ーブとして特開平2−277440号公報がある。On the other hand, an intracavity probe for an NMR apparatus has been proposed which inserts a small coil into a body cavity such as a stomach, an esophagus, and an intestine of a living body to image with high sensitivity and high spatial resolution. For example, Japanese Patent Application Laid-Open No. 2-277440 discloses an in-body probe for a rectal-inserted NMR apparatus.
【０００５】[0005]
【発明が解決しようとする課題】上記、従来の技術にお
けるＮＭＲ装置用体腔内プローブは、シャフト上に設け
られたストライプで体腔内への挿入量を表示することに
より、小型コイルの位置決めがなされており、小型コイ
ルと関心領域の位置関係が不明確であった。従って、小
型コイルを適切に関心領域に配置することができないと
いう問題があった。本発明の目的は、従来技術による問
題を解決したＮＭＲ装置用体腔内プローブを提供するこ
とにある。In the above-mentioned prior art intracavity probe for an NMR apparatus, a small coil is positioned by displaying the amount of insertion into the body cavity by a stripe provided on a shaft. Thus, the positional relationship between the small coil and the region of interest was unclear. Therefore, there is a problem that the small coil cannot be appropriately arranged in the region of interest. SUMMARY OF THE INVENTION It is an object of the present invention to provide an intracavity probe for an NMR apparatus which solves the problems of the prior art.
【０００６】[0006]
【課題を解決するための手段】上記目標を達成する基本
的な特徴は、関心領域の核スピンを高周波磁場により励
起もしくは、前記関心領域の核スピンからの核磁気共鳴
信号を検出する体腔内に挿入可能な小型コイルを備える
ＮＭＲ装置用体腔内プローブにおいて、前記小型コイル
の位置を示すマーカを設けたことにある。A basic feature of achieving the above object is that a nuclear spin in a region of interest is excited by a high-frequency magnetic field, or in a body cavity for detecting a nuclear magnetic resonance signal from the nuclear spin in the region of interest. A marker for indicating the position of the small coil is provided in an intracavity probe for an NMR apparatus having a small coil that can be inserted.
【０００７】[0007]
【作用】関心領域の核スピンを高周波磁場により励起も
しくは、前記関心領域の核スピンからの核磁気共鳴信号
を検出する体腔内に挿入可能な小型コイルを備える核磁
気共鳴装置用体腔内プローブにおいて、前記小型コイル
の位置を示すマーカを設けたので、前記小型コイルを適
切に関心領域に配置することができる。An intracavity probe for a nuclear magnetic resonance apparatus including a small coil that can be inserted into a body cavity for exciting a nuclear spin in a region of interest by a high-frequency magnetic field or detecting a nuclear magnetic resonance signal from the nuclear spin in the region of interest, Since the marker indicating the position of the small coil is provided, the small coil can be appropriately arranged in the region of interest.
【０００８】[0008]
【実施例】以下、本発明の実施例を図により説明する。
図１は本発明の一実施例を示す体腔内プローブ先端の断
面図である。コイルカバー１０内には、小型コイル１が
設置され、更に小型コイル１の内側にはマーカ２が設置
されている。マーカ２は、縦緩和時間が被検体（５００
ms程度）よりも十分に短い、塩化マンガン水溶液（５０
ms程度）で充たされ十字型をしている。マーカ２が十字
型であるのは、撮像されたマーカ２の形状から小型コイ
ル１の方向が分かるようにするためである。例えば、撮
像されたマーカ２の形状が十字型をしている場合、小型
コイル１は撮像断面と水平であり、傾いた一本線をして
いる場合、小型コイル１は撮像断面と直交し傾いている
など小型コイル１の位置のみならず方向まで分かる。マ
ーカ２は塩化マンガン水溶液のほか、塩化ニッケル，硫
酸銅等の水溶液あるいはゲル，固体等であってもよい。
また、形状も十字型のほか、矩形，菱形，楕円等であっ
てもよく、図１に示したような信号検出コイルの内側に
設置することは必ずしも必要ではない。コイルカバーの
内側に設置することも可能である。DESCRIPTION OF THE PREFERRED EMBODIMENTS Embodiments of the present invention will be described below with reference to the drawings.
FIG. 1 is a sectional view of the tip of a probe in a body cavity showing one embodiment of the present invention. The small coil 1 is installed in the coil cover 10, and the marker 2 is installed inside the small coil 1. The marker 2 indicates that the longitudinal relaxation time of the subject (500
manganese chloride aqueous solution (50 ms)
ms) and has a cross shape. The reason why the marker 2 is cross-shaped is that the direction of the small coil 1 can be determined from the shape of the marker 2 captured. For example, when the shape of the imaged marker 2 has a cross shape, the small coil 1 is horizontal to the imaging section, and when the marker 2 has an inclined single line, the small coil 1 is inclined perpendicular to the imaging section. It is possible to know not only the position of the small coil 1 but also the direction. The marker 2 may be an aqueous solution of nickel chloride, copper sulfate or the like, a gel, a solid, or the like, in addition to the manganese chloride aqueous solution.
The shape may be a rectangle, a rhombus, an ellipse, or the like in addition to the cross shape, and it is not always necessary to install the signal detection coil inside the signal detection coil as shown in FIG. It is also possible to install inside the coil cover.
【０００９】小型コイル１の位置検出は、信号計測の繰
返し時間ＴＲが５〜１００ms程度であるフラッシュ等の
高速シーケンスを用い、通常の腹部用コイルでマーカ２
を撮像することにより行われる。高速シーケンスでの撮
像によりマーカ２が画像化され、被検体中の関心領域に
対するマーカ２、すなわち、小型コイル１の位置が検出
される。この位置検出の結果により、体腔内プローブの
挿入量が調整される。従って、位置検出を繰り返すこと
で小型コイル１が適切に関心領域に配置される。繰返し
時間ＴＲが５００ms程度であるスピンエコー等の通常シ
ーケンスで関心領域の撮像をする場合、マーカ２は緩和
時間が被検体より十分に短いため撮像されず、関心領域
の画像に何ら影響しない。The position detection of the small coil 1 uses a high-speed sequence such as a flash in which the repetition time TR of signal measurement is about 5 to 100 ms.
This is performed by capturing an image. The marker 2 is imaged by imaging in the high-speed sequence, and the position of the marker 2, that is, the position of the small coil 1 with respect to the region of interest in the subject is detected. Based on the result of the position detection, the insertion amount of the intracavity probe is adjusted. Therefore, the small coil 1 is appropriately arranged in the region of interest by repeating the position detection. When the region of interest is imaged in a normal sequence such as a spin echo having a repetition time TR of about 500 ms, the marker 2 is not imaged because the relaxation time is sufficiently shorter than the subject, and does not affect the image of the region of interest.
【００１０】図において、小型コイル１は、図示してい
ない共振用直列コンデンサを含む１ターンの正方形コイ
ルであるが、矩形，円形，楕円形等のコイルであっても
同様である。なお、小型コイル１の位置検出は、マーカ
２のみでなくジャイロ等の手段によっても可能である。In FIG. 1, the small coil 1 is a one-turn square coil including a resonance series capacitor (not shown), but the same applies to a rectangular, circular, elliptical or other coil. The position of the small coil 1 can be detected not only by the marker 2 but also by means such as a gyro.
【００１１】図２は本発明の一実施例を示す方向制御手
段を備えた体腔内プローブ先端の図であり、図３は図２
を横から見た図である。可撓性の挿入部１１の先端には
回転伝達部１２の一端が接続され、回転伝達部１２の他
端には、内部に小型コイル１とマーカ（図示せず）が設
置されているコイルカバー１０が接続されている。FIG. 2 is a view of a tip of a probe in a body cavity having a direction control means according to an embodiment of the present invention, and FIG.
It is the figure which looked at from the side. One end of a rotation transmitting section 12 is connected to the distal end of the flexible insertion section 11, and the other end of the rotation transmitting section 12 has a coil cover in which the small coil 1 and a marker (not shown) are installed. 10 are connected.
【００１２】小型コイル１の方向制御は、磁場の影響を
受けない超音波モ−タ等(図示せず)により、回転伝達部
１２に接続されたコイルカバー１０を回転させ、前記小
型コイル１の感度方向が被検体の関心領域に向くように
して行われる。従って、方向制御を繰り返すことによ
り、小型コイル１が適切に関心領域に配置される。The direction of the small coil 1 is controlled by rotating the coil cover 10 connected to the rotation transmitting section 12 by an ultrasonic motor or the like (not shown) which is not affected by a magnetic field. This is performed so that the sensitivity direction is directed to the region of interest of the subject. Therefore, by repeating the direction control, the small coil 1 is appropriately arranged in the region of interest.
【００１３】図において、回転伝達部１２は挿入部１１
の先端であるが、後端であっても同様である。また、本
実施例ではコイルカバー１０は半円柱状であるが、小型
コイル１の感度領域の妨げにならない形状であればこの
限りではない。なお、小型コイル１の方向制御は、回転
制御のみならず撓み，ねじれ等の制御であっても同様で
ある。In the drawing, a rotation transmitting section 12 is provided with an insertion section 11.
, But the same applies to the rear end. In the present embodiment, the coil cover 10 has a semi-cylindrical shape, but the shape is not limited as long as the shape does not hinder the sensitivity region of the small coil 1. The direction control of the small coil 1 is the same not only for the rotation control but also for the control of bending, twisting, and the like.
【００１４】[0014]
【発明の効果】本発明によれば、関心領域の核スピンを
高周波磁場により励起もしくは、関心領域の核スピンか
らの核磁気共鳴信号を検出する体腔内に挿入可能な小型
コイルを備える核磁気共鳴装置用体腔内プローブにおい
て、小型コイルの位置を示すマーカを設けたので、小型
コイルを適切に関心領域に配置することができる。According to the present invention, a nuclear magnetic resonance having a small coil which can be inserted into a body cavity for exciting nuclear spins in a region of interest by a high-frequency magnetic field or detecting a nuclear magnetic resonance signal from the nuclear spins in the region of interest. Since the marker indicating the position of the small coil is provided in the intra-body cavity probe for the device, the small coil can be appropriately arranged in the region of interest.
【図１】本発明の一実施例を示すプローブ先端部の断面
図。FIG. 1 is a cross-sectional view of a probe tip showing one embodiment of the present invention.
【図２】本発明の一実施例を示すプローブの概略平面
図。FIG. 2 is a schematic plan view of a probe showing one embodiment of the present invention.
【図３】本発明の一実施例を示すプローブの概略平面
図。FIG. 3 is a schematic plan view of a probe showing one embodiment of the present invention.
１…小型コイル、２…マーカ、１０…コイルカバー、１
１…挿入部、１２…回転伝達部。1: small coil, 2: marker, 10: coil cover, 1
1 ... insertion section, 12 ... rotation transmission section.
───────────────────────────────────────────────────── フロントページの続き (72)発明者 ▲高▼橋 哲彦 東京都国分寺市東恋ケ窪１丁目280番地 株式会社 日立製作所 中央研究所内 (72)発明者 山本 悦治 東京都国分寺市東恋ケ窪１丁目280番地 株式会社 日立製作所 中央研究所内 (56)参考文献 特開 平３−228741（ＪＰ，Ａ) 特開 昭61−13974（ＪＰ，Ａ) (58)調査した分野(Int.Cl.7，ＤＢ名) A61B 5/055 ＪＩＣＳＴファイル（ＪＯＩＳ)──────────────────────────────────────────────────続 き Continuing on the front page (72) Inventor ▲ Takahiko Hashi 1-280 Higashi-Koikekubo, Kokubunji-shi, Tokyo Inside the Central Research Laboratory, Hitachi, Ltd. (72) Etsuji Yamamoto 1-1280 Higashi-Koikekubo, Kokubunji-shi, Tokyo Stock (56) References JP-A-3-228741 (JP, A) JP-A-61-13974 (JP, A) (58) Fields investigated (Int. Cl. 7 , DB name) A61B 5/055 JICST file (JOIS)
Claims (5)
ピンを高周波磁場により励起、又は前記関心領域の前記
核スピンからの核磁気共鳴信号を検出するコイルを具備
する核磁気共鳴装置用体腔内プローブに於いて、前記コ
イルの位置を示すマーカを有し、前記マーカは、緩和時
間が前記被検体の緩和時間より短い物質から構成される
ことを特徴とする核磁気共鳴装置用体腔内プローブ。1. A nuclear magnetic resonance apparatus having a coil inserted into a body cavity of a subject to excite nuclear spins in a region of interest by a high-frequency magnetic field or to detect a nuclear magnetic resonance signal from the nuclear spins in the region of interest. in use body cavity probe, have a marker indicating the position of the coil, the marker is relaxation time
An intracorporeal probe for a nuclear magnetic resonance apparatus, wherein the probe is made of a substance whose interval is shorter than the relaxation time of the subject .
プローブに於いて、前記マーカは、塩化マンガン、塩化
ニッケル、硫酸銅を含むことを特徴とする核磁気共鳴装
置用体腔内プローブ。2. The probe according to claim 1, wherein the markers are manganese chloride, chloride,
An intracavity probe for a nuclear magnetic resonance apparatus , comprising nickel and copper sulfate .
プローブに於いて、前記マーカの形状が十字型であるこ
とを特徴とする核磁気共鳴装置用体腔内プローブ。3. The intracavity probe for a nuclear magnetic resonance apparatus according to claim 1, wherein the marker has a cross shape. .
ピンを高周波磁場により励起、又は前記関心領域の前記
核スピンからの核磁気共鳴信号を検出するコイルを具備
する核磁気共鳴装置用体腔内プローブに於いて、前記コ
イルの位置を示すマーカと、前記コイルの方向を制御す
る方向制御手段とを有することを特徴とする核磁気共鳴
装置用体腔内プローブ。4. A nuclear magnetic resonance apparatus having a coil inserted into a body cavity of a subject to excite nuclear spins in a region of interest by a high-frequency magnetic field or to detect a nuclear magnetic resonance signal from the nuclear spins in the region of interest. in use body cavity probe, said co
An intracavity probe for a nuclear magnetic resonance apparatus , comprising: a marker indicating a position of an il; and a direction control means for controlling a direction of the coil.
プローブに於いて、前記方向制御手段は前記コイルの回
転制御を行なうことを特徴とする核磁気共鳴装置用体腔
内プローブ。5. A body cavity for a nuclear magnetic resonance apparatus according to claim 4.
In the probe, the direction control means may be configured to rotate the coil.
An intracavity probe for a nuclear magnetic resonance apparatus, which performs rotation control .
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10089592A JP3185344B2 (en) | 1992-04-21 | 1992-04-21 | In-vivo probe for nuclear magnetic resonance equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10089592A JP3185344B2 (en) | 1992-04-21 | 1992-04-21 | In-vivo probe for nuclear magnetic resonance equipment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH05293094A JPH05293094A (en) | 1993-11-09 |
| JP3185344B2 true JP3185344B2 (en) | 2001-07-09 |
Family
ID=14286078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10089592A Expired - Fee Related JP3185344B2 (en) | 1992-04-21 | 1992-04-21 | In-vivo probe for nuclear magnetic resonance equipment |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3185344B2 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102032235B1 (en) | 2018-03-12 | 2019-10-16 | 프레임바이 주식회사 | Employee ID card case |
| KR102080298B1 (en) | 2019-09-26 | 2020-02-21 | 프레임바이 주식회사 | Employee ID card case |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9514877D0 (en) * | 1995-07-20 | 1995-09-20 | Marconi Gec Ltd | Magnetic resonance methods and apparatus |
| JP4634570B2 (en) * | 2000-06-05 | 2011-02-16 | 株式会社東芝 | MRI equipment |
-
1992
- 1992-04-21 JP JP10089592A patent/JP3185344B2/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102032235B1 (en) | 2018-03-12 | 2019-10-16 | 프레임바이 주식회사 | Employee ID card case |
| KR102080298B1 (en) | 2019-09-26 | 2020-02-21 | 프레임바이 주식회사 | Employee ID card case |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05293094A (en) | 1993-11-09 |
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Legal Events
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| LAPS | Cancellation because of no payment of annual fees |