JPH0347852B2 - - Google Patents
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- Publication number
- JPH0347852B2 JPH0347852B2 JP57198662A JP19866282A JPH0347852B2 JP H0347852 B2 JPH0347852 B2 JP H0347852B2 JP 57198662 A JP57198662 A JP 57198662A JP 19866282 A JP19866282 A JP 19866282A JP H0347852 B2 JPH0347852 B2 JP H0347852B2
- Authority
- JP
- Japan
- Prior art keywords
- magnetic field
- static magnetic
- static
- nmr
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000005291 magnetic effect Effects 0.000 claims description 69
- 238000005481 NMR spectroscopy Methods 0.000 claims description 34
- 230000003068 static effect Effects 0.000 claims description 28
- 238000001514 detection method Methods 0.000 claims description 19
- 210000005239 tubule Anatomy 0.000 claims description 3
- 238000010586 diagram Methods 0.000 description 9
- 206010028980 Neoplasm Diseases 0.000 description 8
- 201000011510 cancer Diseases 0.000 description 7
- 230000002159 abnormal effect Effects 0.000 description 6
- 238000012545 processing Methods 0.000 description 5
- 230000005856 abnormality Effects 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 3
- 210000001035 gastrointestinal tract Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 230000005294 ferromagnetic effect Effects 0.000 description 2
- 230000003211 malignant effect Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- 208000000453 Skin Neoplasms Diseases 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000005311 nuclear magnetism Effects 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
Landscapes
- Magnetic Resonance Imaging Apparatus (AREA)
- Endoscopes (AREA)
Description
【発明の詳細な説明】
本発明は、人体の消化器管内表面に発生する表
皮ガン等を検出診断するNMR内視鏡診断装置に
関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an NMR endoscopic diagnostic apparatus for detecting and diagnosing epidermal cancer and the like occurring on the inner surface of the gastrointestinal tract of the human body.
従来、人体の消化器管内表面、特に胃壁上層部
等に発生する表皮ガンの検出診断については、内
視鏡あるいはＸ線撮影等によつて発生部位を検出
し、その部位の生体組織を採取して悪性か否かを
診断する方法が一般的である。ところが、このよ
うな従来の表皮ガンの検出診断方法は相対的な診
断が容易でないために、試料採取部位が比較的広
範囲となるので、即時診断を下すことが出来ない
という欠点があつた。さらに生体組織を採取する
労力も多大となる上、試料採取のために人体を傷
つけねばならないという欠点があつた。 Conventionally, the detection and diagnosis of epidermal cancer that occurs on the inner surface of the human digestive tract, especially the upper layer of the stomach wall, involves detecting the site of cancer using an endoscope or X-ray photography, and then collecting biological tissue from that site. A common method is to diagnose whether or not the tumor is malignant. However, such conventional methods for detecting and diagnosing epidermal skin cancer have the disadvantage that it is not easy to make a relative diagnosis, and the sample collection site is relatively wide, making it impossible to make an immediate diagnosis. Furthermore, there are disadvantages in that it takes a lot of effort to collect living tissue, and the human body has to be injured in order to collect the sample.
一方、これに対して近年、核磁気共鳴
（NMR）現象を応用したNMRスキヤナー、
NMR断層像撮影装置等が利用されている。一般
に、人体を磁場の中に置き、所定の周波数の高周
波を人体に与えると、人体内のスピンを持つ核が
励起し、核は短時間、或る決まつた周波数の信号
（NMR信号）を出してその位置を知らせる。し
たがつて、上記NMRスキヤナー、NMR断層像
撮影装置等のNMR装置は、このNMR信号を検
出してコンピユータで処理することにより、断層
像を得ている。これらのNMR装置によつて得ら
れる断層像はガン等の診断に対して極めて有用で
ある。すなわち、一般にガン細胞と正常細胞とか
ら得られるNMR信号は互いに応答性が異なるの
で、これらの応答時間を測定することにより、ガ
ンか否かの診断が可能である。 On the other hand, in recent years, NMR scanners that apply the nuclear magnetic resonance (NMR) phenomenon,
NMR tomography equipment, etc. are used. Generally, when a human body is placed in a magnetic field and a high frequency wave of a predetermined frequency is applied to the human body, nuclei with spin inside the human body are excited, and the nuclei emit a signal (NMR signal) of a certain predetermined frequency for a short period of time. Take it out and let me know its location. Therefore, NMR devices such as the above NMR scanner and NMR tomographic imaging device obtain tomographic images by detecting this NMR signal and processing it with a computer. Tomographic images obtained by these NMR devices are extremely useful for diagnosing cancer and the like. That is, since NMR signals obtained from cancer cells and normal cells generally have different responses, it is possible to diagnose cancer or not by measuring their response times.
しかしながら、これらのNMR装置は断層像を
得るために膨大なNMR信号を処理しなければな
らず、そのため高速大容量のコンピユータを必要
とし、装置全体が大型となる上、非常に高価格と
なる等の欠点があつた。 However, these NMR devices must process a huge amount of NMR signals in order to obtain tomographic images, which requires a high-speed, large-capacity computer, making the entire device large and extremely expensive. There were some shortcomings.
また、従来より内視鏡観察時において視覚的に
異変箇所を発見した際に、この異変が例えば悪性
のものでであるか否かを或る程度判断したいとい
う要望があり、このような要望に対して上記
NMRスキヤナーは高価・大型であり、さらに視
覚的に異常と認めた箇所と断層像との対応づけが
難しい等の欠点があつた。 Additionally, when an abnormality is visually discovered during endoscopic observation, there has been a desire to determine to some extent whether or not this abnormality is, for example, malignant. For the above
NMR scanners are expensive and large, and they also have drawbacks such as difficulty in correlating visually abnormal areas with tomographic images.
本発明は、以上のような事情に基づいてなされ
たものであり、内視鏡観察時において異変箇所の
診断を即時行なうことができ、小型低廉で、高感
度、且つ高精度のNMR内視鏡診断装置を提供す
ることを目的とするものである。 The present invention has been made based on the above circumstances, and provides a compact, inexpensive, highly sensitive, and highly accurate NMR endoscope that can immediately diagnose abnormalities during endoscopic observation. The purpose is to provide a diagnostic device.
本発明は上記の目的を達成するために、次のよ
うな構成としたことを特徴としている。すなわ
ち、本発明においては、静磁場を形成する静磁場
形成手段と、この静磁場形成手段によつて形成さ
れた静磁場を絶対空間座標のＹ軸回りに回転させ
る静磁場回転手段と、前記静磁場内に配置され前
記絶対空間座標のＸ軸回りに回転可能な可動寝台
と、この可動寝台の上に横たわる被検者の体腔内
に挿入される可撓性細管を有する内視鏡と、前記
可撓性細管の先端部に設けられ前記被検者の体腔
内に高周波磁場を形成して核磁気共鳴信号を検出
する高周波磁場形成手段と、この高周波磁場形成
手段によつて検出された核磁気共鳴信号を信号処
理して前記被検者を診断する手段と、前記可撓性
細管の先端部に設けられ前記静磁場の磁界方向と
前記高周波磁場の磁界方向とが交差する角度を検
出する磁界方向検出手段と、この磁界方向検出手
段から出力された信号に基づいて前記静磁場回転
手段及び前記可動寝台を駆動し、前記静磁場の磁
界方向と前記高周波磁場の磁界方向とを直交させ
る手段とを備えた構成とした。 In order to achieve the above object, the present invention is characterized by having the following configuration. That is, in the present invention, a static magnetic field forming means for forming a static magnetic field, a static magnetic field rotating means for rotating the static magnetic field formed by the static magnetic field forming means around the Y-axis of absolute spatial coordinates, and a a movable bed arranged in a magnetic field and rotatable around the X-axis of the absolute spatial coordinate; an endoscope having a flexible tubule inserted into a body cavity of a subject lying on the movable bed; a high-frequency magnetic field forming means provided at the tip of the flexible thin tube for detecting nuclear magnetic resonance signals by forming a high-frequency magnetic field in the body cavity of the subject; and nuclear magnetism detected by the high-frequency magnetic field forming means. means for diagnosing the subject by signal processing resonance signals; and a magnetic field provided at the tip of the flexible thin tube to detect the angle at which the magnetic field direction of the static magnetic field and the magnetic field direction of the high-frequency magnetic field intersect. a direction detecting means; and a means for driving the static magnetic field rotation means and the movable bed based on a signal output from the magnetic field direction detecting means to make the magnetic field direction of the static magnetic field and the magnetic field direction of the high frequency magnetic field orthogonal. The configuration is equipped with the following.
以下、図面に示す実施例に基づいて本発明を詳
細に説明する。 Hereinafter, the present invention will be explained in detail based on embodiments shown in the drawings.
第１図〜第５図はいずれも本発明の一実施例を
説明するための図で、第１図は本装置の概略構成
を示す図で、第２図は同実施例の内視鏡先端部の
構造を示す図で、第３図は上記内視鏡先端部に設
けられた磁界方向検出素子の構成を示す図で、第
４図は上記磁界方向検出素子の検出方法を説明す
る図である。また、第５図は磁界方向検出素子及
び高周波コイルの信号処理系を示すブロツク図で
ある。 Figures 1 to 5 are diagrams for explaining one embodiment of the present invention. Figure 1 is a diagram showing a schematic configuration of this device, and Figure 2 is a diagram showing the endoscope tip of the same embodiment. FIG. 3 is a diagram showing the configuration of the magnetic field direction detection element provided at the distal end of the endoscope, and FIG. 4 is a diagram illustrating the detection method of the magnetic field direction detection element. be. Further, FIG. 5 is a block diagram showing a signal processing system of the magnetic field direction detection element and the high frequency coil.
第１図に示すように、本実施例のNMR内視鏡
診断装置は、可動マグネツト１、可動寝台２、内
視鏡３、可動マグネツト及び可動寝台駆動部（以
下駆動部という）４、NMR信号測定部５とから
構成されている。 As shown in FIG. 1, the NMR endoscope diagnostic apparatus of this embodiment includes a movable magnet 1, a movable bed 2, an endoscope 3, a movable magnet and movable bed drive section (hereinafter referred to as the drive section) 4, and an NMR signal. It is composed of a measuring section 5.
可動マグネツト１は一対の磁石からなつてお
り、静磁場を形成する。また、この可動マグネツ
ト１は図示しない静磁場回転手段により矢印Ａで
示すように、絶対空間座標系を形成するＸ軸、Ｙ
軸及びＺ軸のうちＹ軸回りに回転するようになつ
ている。 The movable magnet 1 consists of a pair of magnets and forms a static magnetic field. Moreover, this movable magnet 1 is moved by a static magnetic field rotating means (not shown) to the X-axis, Y-axis, which forms an absolute spatial coordinate system, as shown by arrow A.
It is configured to rotate around the Y axis of the axis and the Z axis.
可動寝台２は上記可動マグネツト１によつて形
成される静磁場内に設けられており、矢印Ｂで示
すように絶対空間座標系を形成するＸ軸、Ｙ軸及
びＺ軸のうちＸ軸回りに回転可能となつている。 The movable bed 2 is installed in the static magnetic field formed by the movable magnet 1, and as shown by the arrow B, the movable bed 2 is arranged around the X axis among the X, Y, and Z axes forming an absolute spatial coordinate system. It is rotatable.
内視鏡３は操作部３Ａと可撓性細管３Ｂとから
なつており、可撓性細管３Ｂの先端部には第２図
に示すようにレンズ３１ａ及びイメージガイド３
１ｂからなる直視型光学系の他に磁界方向検出セ
ンサ３２及び高周波コイル３３が設けられてい
る。直視型光学系のイメージガイド３１ｂは可撓
性細管３Ｂ内を挿通して操作部３Ａに達してお
り、人体の消化器管内表面を視覚的に観察可能と
なつている。 The endoscope 3 consists of an operating section 3A and a flexible thin tube 3B, and the flexible thin tube 3B has a lens 31a and an image guide 3 at its distal end, as shown in FIG.
In addition to the direct-view optical system consisting of 1b, a magnetic field direction detection sensor 32 and a high frequency coil 33 are provided. The image guide 31b of the direct viewing optical system passes through the flexible thin tube 3B and reaches the operating section 3A, making it possible to visually observe the inner surface of the human digestive tract.
一方、磁界方向検出センサ３２及び高周波コイ
ル３３は直視型光学系の近傍に形成された中空円
筒部３４内に設けられている。磁界方向検出セン
サ３２は第３図に示すように互いに検出面が直交
して共通の交軸ｌを持つ２枚の強磁性薄膜センサ
３２ａ，３２ａからなつており、しかも交軸ｌが
高周波コイル３３の中心軸Ｌと同軸又は平行とな
るように固定されている。また、この磁界検出セ
ンサ３３の表面はシヨート等を防ぐためにモール
ドで覆われている。したがつて、この磁界方向検
出センサ３２は可動マグネツト１によつて形成さ
れる静磁場を第４図に示すようにベクトルＨ→で表
わすと、このベクトルＨ→は直角なxy面内でｘ方
向成分Ｈ→ｘとｙ方向成分Ｈ→ｙに分解され、静磁場
Ｈ→と高周波コイルの中心軸Ｌ→とのなす角度が検出
される。 On the other hand, the magnetic field direction detection sensor 32 and the high-frequency coil 33 are provided in a hollow cylindrical portion 34 formed near the direct-view optical system. As shown in FIG. 3, the magnetic field direction detection sensor 32 consists of two ferromagnetic thin film sensors 32a, 32a whose detection surfaces are perpendicular to each other and have a common transverse axis l, and the transverse axis l is connected to the high-frequency coil 33. It is fixed so as to be coaxial or parallel to the central axis L of. Further, the surface of the magnetic field detection sensor 33 is covered with a mold to prevent shoots and the like. Therefore, when the static magnetic field formed by the movable magnet 1 is represented by a vector H→ as shown in FIG. It is decomposed into a component H→x and a y-direction component H→y, and the angle between the static magnetic field H→ and the central axis L→ of the high-frequency coil is detected.
また、高周波コイル３３は後述するNMR信号
測定部５から送出される高周波によつて体腔内の
被検査部位に高周波磁場を形成して被検査部位の
NMR信号を検出よるものである。 In addition, the high-frequency coil 33 forms a high-frequency magnetic field at the test site in the body cavity using high-frequency waves sent from the NMR signal measuring section 5, which will be described later.
It is based on detecting NMR signals.
これらの磁界方向検出センサ３２及び高周波コ
イル３３は可撓性細管３Ｂ内を挿通するリード線
l1，l2を通じて駆動部４、NMR信号測定部５と
接続しており、駆動部４は第５図に示すように信
号処理回路４１、可動マグネツト駆動回路４２、
可動寝台駆動回路４３とから構成されている。す
なわち、この駆動部４は磁界方向検出センサ３２
によつて検出された静磁場Ｈ→と高周波コイル３３
の中心軸Ｌ→との角度に従つて、静磁場と高周波磁
場が直交するように可動マグネツト１及び可動寝
台２の両方をリード線l3を介して駆動させる。 These magnetic field direction detection sensor 32 and high frequency coil 33 are lead wires inserted into the flexible thin tube 3B.
It is connected to the drive unit 4 and the NMR signal measurement unit 5 through l 1 and l 2 , and the drive unit 4 has a signal processing circuit 41, a movable magnet drive circuit 42, and a movable magnet drive circuit 42, as shown in FIG.
It is composed of a movable bed driving circuit 43. That is, this drive unit 4 is connected to the magnetic field direction detection sensor 32.
The static magnetic field H→ detected by the high-frequency coil 33
Both the movable magnet 1 and the movable bed 2 are driven via the lead wire l3 so that the static magnetic field and the high-frequency magnetic field are perpendicular to each other according to the angle with the central axis L→.
一方、NMR信号測定部５は上述したように高
周波コイル３３に所定周波数の高周波を送出し、
これによつて高周波コイル３３から検出される被
検査部位のNMR信号の応答時間を測定して被検
査部位の生理的変化を検出診断する。 On the other hand, the NMR signal measuring section 5 sends a high frequency wave of a predetermined frequency to the high frequency coil 33 as described above.
Thereby, the response time of the NMR signal of the inspected site detected from the high frequency coil 33 is measured, and physiological changes in the inspected site are detected and diagnosed.
次に、以上の如き構成の本装置を操作する場合
について説明する。 Next, the operation of the apparatus configured as described above will be explained.
先ず、第１図に示すように被検者１０を本装置
の可動寝台２の上に乗せ、可動マグネツト１の静
磁場を被検者１０に浴びせる。この状態で被検者
１０の口腔から内視鏡３の可撓性細管３Ｂを挿入
して胃壁上層部等を直視型観察光学系にて観察す
る。このとき、例えば胃壁上層部に異常部位１０
ａを発見したとすると、操作部３Ａを操作して、
第２図に示すように高周波コイル３３を異常部位
１０ａに押し当てる。ここで、駆動部４は磁界方
向検出センサ３２からの出力信号に基づいて静磁
場の磁界方向と高周波磁場の磁界方向とが直交す
るまで可動マグネツト１及び可動寝台２を回転さ
せる。そして、静磁場Ｈ→と高周波磁場とが直交し
たところで、NMR測定部５から高周波コイル３
３に所定周波数の高周波を送出し、異常部位１０
ａのNMR信号を測定する。その結果、異常部位
１０ａの生理的変化、例えばガンか否かの検出診
断が可能となる。 First, as shown in FIG. 1, the subject 10 is placed on the movable bed 2 of this apparatus, and the static magnetic field of the movable magnet 1 is applied to the subject 10. In this state, the flexible tube 3B of the endoscope 3 is inserted into the oral cavity of the subject 10, and the upper layer of the stomach wall and the like are observed using a direct viewing optical system. At this time, for example, an abnormal site 10 in the upper layer of the stomach wall.
Suppose that a is discovered, operate the operation section 3A,
As shown in FIG. 2, the high frequency coil 33 is pressed against the abnormal area 10a. Here, the drive unit 4 rotates the movable magnet 1 and the movable bed 2 based on the output signal from the magnetic field direction detection sensor 32 until the magnetic field direction of the static magnetic field and the magnetic field direction of the high frequency magnetic field are perpendicular to each other. Then, when the static magnetic field H → and the high-frequency magnetic field intersect at right angles, the high-frequency coil 3 is transmitted from the NMR measuring section 5.
A high frequency wave of a predetermined frequency is sent to the abnormal area 10.
Measure the NMR signal of a. As a result, it becomes possible to detect and diagnose physiological changes in the abnormal region 10a, for example, whether or not it is cancer.
このように、本実施例においては内視鏡３の先
端部にNMR信号検出用の高周波コイル３３が設
けられているので、内視鏡観察時において異変箇
所の診断を即時行なうことができ、さらに内視鏡
３の先端部に磁界方向検出センサ３２が設けられ
ているので、高感度、且つ高精度のNMR測定を
行うことができる。 In this way, in this embodiment, the high frequency coil 33 for detecting NMR signals is provided at the tip of the endoscope 3, so abnormalities can be immediately diagnosed during endoscopic observation. Since the magnetic field direction detection sensor 32 is provided at the tip of the endoscope 3, highly sensitive and highly accurate NMR measurement can be performed.
また、本実施例によればNMRスキヤナーのよ
うに高速大容量のコンピユータを必要としないの
で、小型で低価格の装置が可能である。 Further, according to this embodiment, unlike an NMR scanner, a high-speed, large-capacity computer is not required, so a compact and low-cost device is possible.
以上述べたように本発明によれば、内視鏡観察
時において異変箇所の診断を即時行なうことがで
き、小型低廉で、高精度且つ高感度のNMR内視
鏡診断装置を提供できる。 As described above, according to the present invention, abnormal locations can be immediately diagnosed during endoscopic observation, and a compact, inexpensive, highly accurate, and highly sensitive NMR endoscopic diagnostic apparatus can be provided.
第１図〜第５図はいずれも本発明の一実施例を
示すもので、第１図はNMR内視鏡診断装置の概
略構成図、第２図は内視鏡先端部の断面図、第３
図は磁界方向検出センサの構成図、第４図は上記
検出センサの検出方法を説明する説明図、第５図
は上記検出センサ及び高周波コイルの信号処理過
程を示すブロツク図である。
１……可動マグネツト、２……可動寝台、３…
…内視鏡、４……駆動部、５……NMR信号測定
部、３２……磁界方向検出センサ、３２ａ……強
磁性薄膜センサ、３４……高周波コイル。
Figures 1 to 5 all show an embodiment of the present invention, with Figure 1 being a schematic configuration diagram of an NMR endoscopic diagnostic device, Figure 2 being a cross-sectional view of the tip of the endoscope; 3
4 is an explanatory diagram illustrating the detection method of the above-mentioned detection sensor, and FIG. 5 is a block diagram showing the signal processing process of the above-mentioned detection sensor and high-frequency coil. 1...Movable magnet, 2...Movable bed, 3...
...Endoscope, 4...Drive unit, 5...NMR signal measurement unit, 32...Magnetic field direction detection sensor, 32a...Ferromagnetic thin film sensor, 34...High frequency coil.
Claims (1)
磁場形成手段によつて形成された静磁場を絶対空
間座標のＹ軸回りに回転させる静磁場回転手段
と、前記静磁場内に配置され前記絶対空間座標の
Ｘ軸回りに回転可能な可動寝台と、この可動寝台
の上に横たわる被検者の体腔内に挿入される可撓
性細管を有する内視鏡と、前記可撓性細管の先端
部に設けられ前記被検者の体腔内に高周波磁場を
形成して核磁気共鳴信号を検出する高周波磁場形
成手段と、この高周波磁場形成手段によつて検出
された核磁気共鳴信号を信号処理して前記被検者
を診断する手段と、前記可撓性細管の先端部に設
けられ前記静磁場の磁界方向と前記高周波磁場の
磁界方向とが交差する角度を検出する磁界方向検
出手段と、この磁界方向検出手段から出力された
信号に基づいて前記静磁場回転手段及び前記可動
寝台を駆動し、前記静磁場の磁界方向と前記高周
波磁場の磁界方向とを直交させる手段とを具備し
たことを特徴とするNMR内視鏡診断装置。1. A static magnetic field forming means for forming a static magnetic field, a static magnetic field rotating means for rotating the static magnetic field formed by the static magnetic field forming means around the Y-axis of absolute spatial coordinates, and a static magnetic field rotating means disposed within the static magnetic field and configured to A movable bed rotatable around the X-axis of absolute spatial coordinates, an endoscope having a flexible tubule inserted into the body cavity of a subject lying on the movable bed, and a tip of the flexible tubule. a high-frequency magnetic field forming means installed in the body cavity of the subject to detect a nuclear magnetic resonance signal by forming a high-frequency magnetic field in the body cavity of the subject; a means for diagnosing the subject, a magnetic field direction detecting means provided at the distal end of the flexible thin tube and detecting an angle at which the magnetic field direction of the static magnetic field and the magnetic field direction of the high frequency magnetic field intersect; It is characterized by comprising means for driving the static magnetic field rotation means and the movable bed based on the signal output from the magnetic field direction detection means, and for making the magnetic field direction of the static magnetic field and the magnetic field direction of the high-frequency magnetic field orthogonal. NMR endoscopic diagnostic equipment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57198662A JPS5988140A (en) | 1982-11-12 | 1982-11-12 | Nmr endoscope diagnostic apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57198662A JPS5988140A (en) | 1982-11-12 | 1982-11-12 | Nmr endoscope diagnostic apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5988140A JPS5988140A (en) | 1984-05-22 |
| JPH0347852B2 true JPH0347852B2 (en) | 1991-07-22 |
Family
ID=16394953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57198662A Granted JPS5988140A (en) | 1982-11-12 | 1982-11-12 | Nmr endoscope diagnostic apparatus |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5988140A (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0334166Y2 (en) * | 1985-10-08 | 1991-07-19 | ||
| JP2563283B2 (en) * | 1986-11-21 | 1996-12-11 | 株式会社東芝 | Magnetic resonance diagnostic device |
| JP2615042B2 (en) * | 1987-04-27 | 1997-05-28 | オリンパス光学工業株式会社 | Endoscope for strong magnetic field |
| US5035231A (en) * | 1987-04-27 | 1991-07-30 | Olympus Optical Co., Ltd. | Endoscope apparatus |
| JPS63270039A (en) * | 1987-04-28 | 1988-11-08 | Olympus Optical Co Ltd | Endoscope |
| JP2575398B2 (en) * | 1987-08-10 | 1997-01-22 | オリンパス光学工業株式会社 | Antenna device for NMR measurement |
| JPS6443242A (en) * | 1987-08-10 | 1989-02-15 | Olympus Optical Co | Endoscope |
| US4960106A (en) * | 1987-04-28 | 1990-10-02 | Olympus Optical Co., Ltd. | Endoscope apparatus |
| JPS63275332A (en) * | 1987-05-06 | 1988-11-14 | Olympus Optical Co Ltd | Endoscope |
| JPH01305937A (en) * | 1988-06-02 | 1989-12-11 | Toshiba Corp | Magnetic resonance diagnosis device |
| US5427103A (en) * | 1992-06-29 | 1995-06-27 | Olympus Optical Co., Ltd. | MRI apparatus for receiving nuclear-magnetic resonance signals of a living body |
| US8195273B2 (en) * | 2004-02-02 | 2012-06-05 | Esaote S.P.A. | Magnetic resonance imaging apparatus |
-
1982
- 1982-11-12 JP JP57198662A patent/JPS5988140A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5988140A (en) | 1984-05-22 |
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