JP3175627U - Vessel bottom cover and vessel - Google Patents

Abstract

A vessel bottom cover is provided that enables the contents of the vessel to be enlarged and viewed.
A vessel bottom cover attached to the bottom of a vessel having a cylindrical body and a hemispherical bottom, the vessel bottom cover having a recess for fitting with the hemispherical bottom of the vessel. A vessel bottom cover, which is a column having an upper surface and is made of a transparent resin or a transparent inorganic material.
[Selection] Figure 1

Description

  The present invention relates to a cover and a vessel that are attached to the bottom of a vessel.

  As in the dissolution test method described in Non-developed Document 1, oral preparations are required to be tested in conformity with dissolution test standards. The dissolution test is performed using a specified vessel. At this time, the vessel is installed in a constant temperature water tank of an appropriate size, or placed in a constant temperature jacket or the like and heated.

  Conventionally, many testing machines using a constant temperature water bath have been used, but in recent years, testing machines using a constant temperature jacket have come to be used from the viewpoint of simplicity of test operation and high efficiency (non-utility model literature) 1).

Non-utility model literature

Non-utility model literature 1

Fifteenth revision Japanese Pharmacopoeia "Articles and Notes"

  However, since a testing machine using a thermostatic jacket does not use a thermostatic water tank, it has been a problem that it is difficult to visually confirm the state of the contents inside the vessel.

  The present invention has been made to solve the above-described problems, and an object of the present invention is to provide a vessel bottom cover that enables the contents of the vessel to be directly or enlarged and viewed.

  In order to solve the above-described problems, the present invention provides a vessel bottom cover that is attached to the bottom of a vessel having a cylindrical body and a hemispherical bottom, and is a recess that fits with the hemispherical bottom of the vessel. A vessel bottom cover, characterized in that it is made of a transparent resin or a transparent inorganic material.

  With such a vessel bottom cover, the contents of the vessel can be observed directly or enlarged while taking advantage of the convenience of test operation of the testing machine using the thermostatic jacket, high efficiency, etc. . Therefore, it contributes to further efficiency improvement of the test.

  The vessel bottom cover preferably has a transparent adhesive layer on the inner surface of the recess, or an elastic body on the bottom surface of the column, so that the vessel bottom cover is attached to the bottom of the vessel. Thereby, it becomes a vessel bottom cover that can be easily detachably fitted to the vessel bottom.

  Furthermore, the vessel bottom cover preferably has a concentric memory on the bottom surface. By having such a memory, it becomes a vessel bottom cover that allows visual confirmation of where the contents are located at the bottom of the vessel during the test.

  The bottom surface of the vessel bottom cover may have a bottom recess.

  Furthermore, it is preferable that a plurality of the concave portions are provided and a plurality of vessels can be attached. Thereby, it can mount | wear with respect to several vessel at once, and operating efficiency improves further.

  The vessel bottom cover has a cylindrical body and hemisphere having a height of 160 to 210 mm, an inner diameter of 98 to 106 mm, a height of 280 to 300 mm, an inner diameter of 98 to 106 mm, or a height of 280 to 300 mm and an inner diameter of 145 to 155 mm. The upper surface may have a recess that fits with the hemispherical bottom of the vessel having a shaped bottom. If it is such, it will become a vessel bottom part cover which can be fitted with the hemispherical bottom part of the vessel normalized for the elution test.

  Furthermore, in the present invention, the outer shape is a columnar shape, and the inner shape has a height of 160 to 210 mm, an inner diameter of 98 to 106 mm, a height of 280 to 300 mm, an inner diameter of 98 to 106 mm, or a height of 280 to 300 mm, and an inner diameter of 145. It is a space consisting of a cylindrical body of ˜155 mm and a hemispherical bottom, and provides a vessel made of a transparent resin or a transparent inorganic material.

  If the vessel has such a shape, it has the same shape as that of the vessel with the vessel bottom cover attached, and the contents of the vessel can be enlarged and visually observed as described above. .

  As described above, the vessel bottom cover of the present invention makes it possible to view the contents of the vessel directly or from the front or below from the front or below. In addition, since the bottom of the conventional vessen was a hemispherical object, it could not be left on the tabletop and the liquid level could not be visually observed, but the vessel bottom cover having a flat bottom of the present invention was attached. If it is in a state, the vessel can be left on the table or the liquid level can be visually observed in that state. Furthermore, by having a memory, the position of the contents in the vessel can be confirmed, and the vessel can be detached by an appropriate means. In particular, the vessel bottom cover of the present invention can be suitably used for a vessel for a bathless dissolution tester, which has conventionally been difficult to visually confirm the contents.

  It is the perspective view and sectional drawing which show the vessel bottom cover of this invention.   It is a perspective view which shows the bottom face of the vessel bottom cover of this invention.   It is sectional drawing which shows the aspect at the time of use of the vessel bottom cover of this invention.   It is sectional drawing which shows the time of mounting | wearing the vessel bottom cover of this invention.   It is a perspective view which shows the vessel bottom cover which can be mounted | worn with the several vessel of this invention.   It is sectional drawing which shows the vessel of this invention.

  Hereinafter, the vessel bottom cover and the vessel of the present invention will be described in detail, but the present invention is not limited thereto. As described above, there has been a demand for a vessel bottom cover that allows the contents of the hemispherical bottom of the vessel to be enlarged and viewed.

  As a result of intensive studies to achieve the above-mentioned problems, the present inventor found that the contents of the hemispherical bottom of the vessel can be enlarged and visually confirmed by attaching a vessel bottom cover of a predetermined shape to the vessel. The present invention has been completed.

[Vessel bottom cover]
That is, the vessel bottom cover of the present invention is a vessel bottom cover attached to the bottom of a vessel having a cylindrical body and a hemispherical bottom, the vessel bottom cover being a hemispherical bottom of the vessel Is a column having a recess to be fitted on the upper surface, and is made of a transparent resin or a transparent inorganic material.

-Column shape The vessel bottom cover of the present invention has a column 11 shape. If it is a column shape, it will not restrict | limit in particular, It can be set as a cylinder and a polygonal column, and it is preferable that it is a cylinder especially. Examples of a perspective view and a cross-sectional view of the vessel bottom cover 10 of the present invention are shown in FIGS. As shown in FIG. 1, in the case of a cylinder, the diameter is preferably approximated to the diameter of the vessel (see FIG. 1B). Also, the vessel bottom cover of the present invention can be shaped so that the joint 14 with the vessel faces inward as shown in FIG. Although the joint 14 of the vessel bottom cover of the present invention may be sharp, if the joint port has a shape as shown in FIG. 1C, the handleability of the vessel bottom cover of the present invention is further improved. Is possible. The state in which the vessel bottom cover 10 is fitted to the vessel is shown in FIGS.

-Material The vessel bottom cover of the present invention is made of a transparent resin or an inorganic material. Specifically, glass etc. are illustrated. Thereby, as shown in FIG. 3, the vessel bottom cover 10 allows the contents (medicine 30) of the vessel 20 to be enlarged and visually observed while being attached to the vessel 20. That is, the contents inside the vessel appear to be enlarged by passing the vessel bottom cover from the A direction shown in FIG. In a conventional dissolution tester with a bath, the water in the bath played a role like a lens for enlarging the contents, but the same effect can be obtained in the bathless dissolution tester by using the vessel bottom cover of the present invention. be able to.

-Recessed part which fits into hemispherical bottom part of vessel The vessel bottom part cover of this invention has the recessed part 12 in the upper surface of the column 11, and the recessed part 12 is a shape fitted with the hemispherical bottom part of the vessel 20. FIG. The vessel bottom cover can be fitted to the hemispherical bottom of the vessel at this recess. In particular, it is preferable to have a transparent adhesive layer on the inner surface 12 ′ of the recess (see FIG. 1). By being attached to the vessel via the transparent adhesive layer, the vessel bottom cover is fixed without being particularly supported from below or the like, and the contents of the vessel can be enlarged and visually observed in this state (see FIG. 3). ). In addition, it is preferable from the viewpoint of operability that the attachment through the transparent adhesive layer is detachable.

  In the present invention, the vessel is not particularly limited, but has a cylindrical (cylindrical) body portion and a hemispherical bottom portion, and is exemplified by glass or a transparent and chemically inert material. it can. In particular, the vessel is preferably used for a dissolution test method for oral preparations, having a volume of 1 L, a height (H) of 160 to 210 mm, an inner diameter (W) of 98 to 106 mm, a volume of 2 L, and a height of 280 to Examples are 300 mm, an inner diameter of 98 to 106 mm, or a volume of 4 L, a height of 280 to 300 mm, an inner diameter of 145 to 155 mm, and a protruding portion at the upper part of the vessel (see FIG. 3). Here, the chemically inert material should not be a material that adsorbs the sample in the vessel, reacts with the sample, or interferes with the measurement of the sample.

-Bottom surface of the vessel bottom cover The vessel bottom cover of the present invention may have an elastic body on the bottom surface. Accordingly, the vessel bottom cover is detachably attached to the vessel bottom while being supported by the elastic body from below. In addition, it can also be set as the aspect with which a vessel bottom part cover is mounted | worn by supporting a vessel bottom part cover from upper direction.

  Further, as shown in a perspective view of the bottom surface of the vessel bottom cover of the present invention in FIG. 2 (A), the memory 15 is preferably engraved on the bottom surface of the vessel bottom cover. Thereby, not only can the contents be enlarged and visually checked, but also the position of the contents at the bottom of the vessel can be visually confirmed.

  In addition, it is possible to make the bottom surface 13 of the vessel bottom cover flat or to provide a recess 16 as shown in FIG. Since the conventional vessel has a hemispherical bottom, it could not be left on the tabletop or the liquid level could be visually observed in that state, but the vessel bottom cover of the present invention having a flat bottom was attached. If so, the vessel can be allowed to stand on the table or the liquid level can be visually observed in that state.

-Vessel bottom cover which can mount | wear with several vessel As shown in FIG. 5, the vessel bottom cover 10 'of this invention can also be set as the aspect which can mount | wear with a plurality of vessels. With such an embodiment, it is possible to attach to a plurality of vessels at once, and the operation efficiency is improved. It is also possible to place a plurality of vessels on the table in a standing state.

[Vessel of the present invention]
Furthermore, the outer shape of the vessel 40 of the present invention is columnar, and the inner shape has a height of 160 to 210 mm, an inner diameter of 98 to 106 mm, a height of 280 to 300 mm, an inner diameter of 98 to 106 mm, or a height of 280 to 300 mm. And having a space composed of a cylindrical body having an inner diameter of 145 to 155 mm and a hemispherical bottom, and made of a transparent resin or a transparent inorganic material (FIG. 6). If the vessel has such a shape, the bottom portion is made of a thick transparent resin or a transparent inorganic material, so the vessel bottom cover is mounted while satisfying the standard of the vessel used in the dissolution tester. It has the same shape as the conventional vessel in the state, and as described above, the contents of the vessel can be enlarged and viewed.

  EXAMPLES Hereinafter, although an Example and a comparative example are shown and this invention is demonstrated in detail, this invention is not limited to these.

[Examples and Comparative Examples]
For a vessel having a cylindrical body having a volume of 1 L, a height of 160 mm, and an inner diameter of 98 mm and a hemispherical bottom, a glass vessel bottom cover that fits into the bottom was prepared. The vessel equipped with the cover (Example) and the non-equipped vessel (Comparative Example) were set in the same dissolution tester, and the salicylic acid tablets were stirred in 900 ml of water in each vessel.

  When the contents of the hemispherical bottom of the vessel were visually confirmed, the contents were enlarged in the example, so it was possible to easily visually confirm from the front whether the contents were melted. It was. On the other hand, in the comparative example, whether or not the contents were melted could not be visually confirmed from the front due to the influence of refraction.

  In addition, this invention is not limited to the said embodiment. The above-described embodiment is an exemplification, and any device that has substantially the same configuration as the technical idea described in the claims of the present invention and has the same operational effects can be devised. Are included in the technical scope.

  DESCRIPTION OF SYMBOLS 10,10 '... Vessel bottom cover, 11 ... Column body, 12 ... Recessed part, 12' ... Inner surface of a recessed part, 13 ... Bottom surface, 14 ... Joint, 15 ... Memory, 16 ... Bottom recessed part, 20 ... Vessel, 30 ... Drug, 40 ... Vessel of the present invention, H ... Height, W ... Inner diameter

Claims (7)

A vessel bottom cover attached to the bottom of the vessel having a cylindrical body and a hemispherical bottom,
The vessel bottom cover is a column having a concave portion fitted on the hemispherical bottom of the vessel on the upper surface, and is made of a transparent resin or a transparent inorganic material.   The vessel bottom cover has a transparent adhesive layer on the inner surface of the recess, or an elastic body on the bottom surface of the column body, and is attached to the bottom of the vessel. The vessel bottom cover according to Item 1.   The vessel bottom cover according to claim 1 or 2, wherein the vessel bottom cover has a concentric memory on a bottom surface.   The vessel bottom cover according to any one of claims 1 to 3, wherein the vessel bottom cover has a bottom surface concave portion on a bottom surface.   The vessel bottom cover according to any one of claims 1 to 4, wherein a plurality of the recesses are provided, and a plurality of the vessels can be mounted.   The vessel bottom cover has a cylindrical body having a height of 160 to 210 mm, an inner diameter of 98 to 106 mm, a height of 280 to 300 mm, an inner diameter of 98 to 106 mm, or a height of 280 to 300 mm and an inner diameter of 145 to 155 mm, and a hemispherical shape. The vessel bottom cover according to any one of claims 1 to 5, wherein the vessel has a concave portion that fits into a hemispherical bottom portion of the vessel having a bottom portion. A vessel,
The outer shape of the vessel is a columnar shape,
The inner shape of the vessel is 160-210 mm in height, 98-106 mm in inner diameter, 280-300 mm in height, 98-106 mm in inner diameter, or 280-300 mm in height, and a cylindrical body and hemisphere with an inner diameter of 145-155 mm. A space consisting of the bottom of
A vessel comprising a transparent resin or a transparent inorganic material.

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