JP3069839U - Extracorporeal circulation circuit - Google Patents

Abstract

(57) [Problem] To provide an extracorporeal circulation circuit capable of supplying a clean replenisher to a patient to be used next even if a backflow occurs in the replenisher line from a venous drip chamber. A replenisher line (5a, 5b, 5c, 5d) and / or an infusion line (18a, 18a, 18b, 18d) of a replenisher cleaned by a microfiltration filter (9) in a venous drip chamber (4) attached to a venous circuit (3). Extracorporeal circuit 1 provided with air trap 6.

Description

[Detailed description of the invention]

[0001]

[Technical field to which the invention belongs]

 The present invention relates to an improvement of an extracorporeal circulation circuit used for artificial dialysis.

[0002]

[Problems to be solved by conventional techniques and devices]

 FIG. 4 is a schematic diagram of a conventional extracorporeal circulation circuit 41. One way to reduce or improve the symptoms associated with dialysis amyloid, one of the complications of hemodialysis, is online HDF therapy. With online HDF therapy, dialysate is used directly as a replenisher for the replacement fluid, eliminating the need for a special replenisher, removing unwanted substances up to the large and medium molecular range, and using β2 microglobulin and the like as pathogenic substances. It has become possible to remove low molecular weight protein substances. At this time, purification of the replacement solution (dialysis solution) is important, and a solution from which exothermic substances such as endotoxin (hereinafter abbreviated as “ET”) have been removed is used as a replenisher. Therefore, a line for supplying the replenisher to the venous drip chamber 4 is required.

For example, when the replenisher line 5e and the replenisher pump 7 are not properly mounted, or when extracorporeal circulation is terminated and the replenisher line 5e is removed from the replenisher pump 7, forgetting to close the clamp 17a may occur. When a backflow occurs in the replenisher line 5e due to the cause and the microfiltration filter 9 is contaminated with blood or the like, a patient to be used next uses the contaminated replenisher. In order to solve the above-mentioned problems, the present inventors have conducted intensive studies and arrived at the following invention.

[0004]

[Means for solving the problem]

 [1] The present invention provides a replenisher line 5a, 5b, 5c, 5d and / or an infusion line 18a, 18a for a replenisher which has been cleaned by a precision filtration filter 9 of a venous drip chamber 4 attached to a venous circuit 3. , 18b, 18d is provided with an extracorporeal circuit 1. [2] According to the present invention, the extracorporeal circuit according to [1], wherein the replenisher line 5a includes a clamp 17a, an air trap 6, and a rolling tube 27, and the injection line 18a includes a connector 24a and a clamp 17b. Provide 1. [3] In the present invention, the replenisher line 5b is provided with the clamp 17a, the air trap 6, and the connector 24, and the injection line 18b is provided with the connector 24a, the clamp 17b and the rolling tube 27 in the above [1]. The extracorporeal circuit 1 described is provided. [4] In the present invention, the replenisher line 5c has a clamp 17a and a connector 24, and the injection line 18c has a connector 24a, a clamp 17b, a rolling tube 27 and an air trap 6 in the above [1]. The extracorporeal circuit 1 described is provided. [5] In the present invention, the replenisher line 5d includes a clamp 17a, an air trap 6, a rolling tube 27, and a connector 24, and the injection line 18d includes a connector 24a, a clamp 17b, and an air trap 6. 1] is provided.

[0005]

[Embodiment of the invention]

 FIG. 1 is a schematic view of the extracorporeal circuit 1 of the present invention. The extracorporeal circuit 1 comprises an arterial circuit 2 and a venous circuit 3. The arterial circuit 2 (hereinafter abbreviated as “A circuit”) includes a saline line 16 for replenishing the physiological saline solution 14, a rolling tube attached to the pump 11, a heparin line 15, A side drip chamber 12 is arranged and connected to a dialyzer 13 (hereinafter abbreviated as “DL”). A co-injection member may be installed on the way. The DL 13 is connected to the vein side circuit 3 (hereinafter abbreviated as “V side circuit”), and the vein side drip chamber 4 is arranged and connected to the patient. As in the arterial circuit 2, a co-injection member may be mounted in the middle of the circuit. A replenisher line 5a, a pressure monitor line 25 and a level adjustment line (not shown) are provided upstream of the venous pressure drip chamber 4. The level adjustment line (not shown) may be a co-injected component. The level adjustment line (not shown) can be attached to the replenisher line 5a or the pressure monitor line 25 using a branch pipe or the like. The replenisher line 5 a is a line for introducing a replenisher obtained by purifying the dialysate 8 with a microfiltration filter 9 into the venous drip chamber 4, and connected to the left side of the venous drip chamber 4. It includes from the end to the connector 24 at the right end. Further, a rolling tube 27 to be mounted on the clamp 17a, the air trap 6, and the replenisher pump 7 is arranged in the middle of the replenisher line 5a.

The dialysate 8 is subjected to a large amount of concentrated treatment, passes through the water removal control device 10 by the injection line 18, passes through the side surface of the DL 13, passes through the discharge line 19, and is discharged again through the water removal control device 10. A water removal line 19a that passes through the water removal adjustment device 10 from the middle of the discharge line 19 is provided. Part of the dialysate 8 is filtered from the injection line 18 through the injection line 18f by the microfiltration filter 9 and flows to the injection line 18a. The injection line 18a is a line for introducing a replenisher obtained by purifying the dialysate 8 with a microfiltration filter 9 into the replenisher line 5a, and is a junction point P of tubes provided above and below the microfiltration filter 9. From the right end to the left side connection connector 24a. Further, a clamp 17b is arranged in the middle of the injection line 18a, and a cap 26 is attached to the connection connector 24a. Depending on the type of the dialysis device in which the water removal adjusting device 10 is incorporated, there are some examples of piping in the water removal line 19a and the injection line 18f, but this is one example.

Next, a method of using the extracorporeal circuit 1 will be described. The A-side circuit 2 and the V-side circuit 3 are connected to the DL 13, and the rolling tube of the A-side circuit 2 is mounted on the liquid sending pump 11. The inside of the A-side circuit 2, DL 13, and V-side circuit 3 is washed using the physiological saline solution 14 connected to the raw food line 16, and then the air is removed to fill the inside. As described above, the dialysate 8 is introduced from the inlet 13 on the side of the DL 13 a through the inlet line 18, exits through the outlet 13 b, and is discharged from the outlet line 19. A part of the dialysate 8 passes through the injection lines 18 and 18f as described above and becomes a liquid filtered by the microfiltration filter 9 (hereinafter referred to as “ET removing liquid”). From the connector 24a. The flow is stopped once by the clamp 17b, connected to the connector 24 of the replenisher line 5a, the rolling tube 27 of the replenisher line 5a and the replenisher pump 7 are mounted, the clamp 17b is removed, and the replenisher pump 7 is operated. At the same time as washing the inside of the replenishing solution line 5a, the solution sending pump 11 is operated again using the physiological saline solution 14, and the solution that has washed the inside of the replenishing solution line 5a is discharged. After cleaning, an air trap is provided in the air trap 6, the inside of the replenisher line 5a is filled with an ET removing liquid, and the clamp 17a is closed for safety. The connection connector 24a is provided with a cap 26 which is fitted when not connected to the connection connector 24 of the replenisher line 5a. The connection connectors 24 and 24a may be either male or female, and may be of any shape as long as they are detachable, and a connector having a lock function is preferable. The A side circuit 2 is connected to the patient, the filled physiological saline is replaced with blood, and when the replaced blood comes out from the patient side connection part of the V side circuit 3, it is connected to the patient and the liquid sending pump 11 is operated. And start dialysis. After the dialysis is started, the clamps 17a and 17b are opened and the replenisher pump 7 is operated to start supplying the replenisher. Since the replenisher pump 7 operates in conjunction with the water removal amount set by the water removal controller 10, the replenisher pump 7 is automatically adjusted, and the ET remover is supplied to the venous drip chamber 4 as a replenisher. It is sent and circulated through the venous circuit 3, the patient, the arterial circuit 2, and the DL 13 by the operation of the liquid supply pump 11. When the operation is completed, the water removal by the water removal adjusting device 10 and the supply of the ET removing solution by the replenishing solution pump 7 are stopped. The supply of the dialysate 8 is stopped. The blood in the A-side circuit 2, the DL 13 and the V-side circuit 3 is replaced with the physiological saline 14 and returned into the body. This method is an example of usage, and may differ depending on each facility such as procedures.

The connected replenisher line 5 a and the infusion line 18 a are connected to the replenisher line 19 a by the replenisher pump 7 for adjusting the amount of the ET remover supplied, and the vein-side drip chamber 4 removes ET as a replenisher. Since the liquid is sent and an air reservoir space is formed in the air trap 6 of the replenisher line 5a, even if blood flows backward from the venous drip chamber 4, replenishment contaminated by the air trap 6 is performed. The liquid does not flow in the direction of the microfiltration filter 9.

FIG. 2 is an enlarged view (a) of the air trap 6 according to the present invention and (b) and (c) showing other embodiments. (A) is a cylindrical air trap whose size is about the same as the artery drip chamber 12 (venous drip chamber 4). In (b), a co-injection member 21 is provided upstream of the air trap 6, and a syringe or the like provided with a metal needle is punctured to adjust the liquid level in the air trap 6. In (c), a level adjusting line 22 with a connector 23 is mounted upstream of the air trap 6, and a syringe or the like is connected to the connector 23 to adjust the liquid level in the same manner as in (b). In addition to installing the co-injection member 21 and the level adjustment line 22 installed upstream of the air trap 6, an automatic open / close valve for pressure adjustment that can keep the pressure in the air trap 6 constant can also be installed. .

FIG. 3 is a schematic view of (A), (B) and (C) showing another embodiment of the replenisher line 5a and the injection line 18a of the present invention. In the other embodiments (A), (B), and (C) of the present invention, the replenisher lines 5b, 5c, and 5d are connected from the left end to the right end connected to the venous drip chamber 4 upstream. Including Further, a clamp 17a and an air trap 6 are provided in the middle of the replenisher line 5b, a clamp 17a is provided in the middle of the replenisher line 5c, and a clamp 17a, the air trap 6 and a replenisher pump are provided in the middle of the replenisher line 5d. The rolling tubes 27 to be mounted on the respective 7 are arranged. The injection lines 18b, 18c, and 18d include portions from the right end of the junction P of the tubes provided above and below the microfiltration filter 9 to the connector 24a at the left end. Further, a rolling tube 27 and a clamp 17b to be mounted on the replenisher pump 7 are arranged in the middle of the injection line 18b, and a cap 26 is mounted on the connection connector 24a. In the middle of the injection line 18c, an air trap 6, a rolling tube 27 to be attached to the replenisher pump 7, and a clamp 17b are arranged, and a cap 26 is attached to the connection connector 24a. An air trap 6 and a clamp 17b are arranged in the middle of the injection line 18d, and a cap 26 is attached to the connection connector 24a.

[0011]

[Effects of the invention]

 Air traps in the replenisher lines 5a, 5b, 5c, 5d and / or the injection lines 18a, 18b, 18c, 18d of the replenisher cleaned by the microfiltration filter 9 attached to the venous drip chamber 4 of the extracorporeal circuit 1 Even if a backflow occurs in the direction of the replenisher line 5a (5b, 5c, 5d) from the venous drip chamber 4 by attaching the air trap 6, the air trap 6 is provided with a space for an air reservoir. A clean replenisher can be supplied to the patient for use.

[Brief description of the drawings]

FIG. 1 is a schematic diagram of an extracorporeal circuit 1 of the present invention.

FIG. 2 is an enlarged view of an embodiment (a) of an air trap 6 and enlarged views of other embodiments (b) and (c).

FIG. 3 shows the replenisher line 5a and the injection line 18a of the present invention.
Schematic diagrams of (A), (B), and (C) showing another embodiment of the present invention.

FIG. 4 is a schematic diagram of a conventional extracorporeal circulation circuit 41.

[Explanation of symbols]

 1, 41 extracorporeal circulation circuit 2 arterial circuit 3 venous circuit 4 venous drip chamber 5a, 5b replenisher line 5c, 5d replenisher line 6 air trap 7 replenisher pump 8 dialysate 9 microfiltration filter 10 dewatering device DESCRIPTION OF SYMBOLS 11 Liquid-feeding pump 12 Arterial-side drip chamber 13 Dialyzer 13a Inlet 13b Outlet 14 Physiological saline 15 Heparin line 16 Raw edible line 17a, 17b Clamp 18, 18f Injection line 18a, 18b Injection line 18c, 18d Injection line 19 Drainage line 19a Water line 21 Co-injection member 22 Level adjustment line 23 Connector 24, 24a Connector 25 Pressure monitor line 26 Cap 27 Rolling tube P Tube junction

Claims (5)

[Utility model registration claims] 1. A replenisher line 5a, 5b, 5c, 5d and / or an infusion line 18a, 18a, 18b of a replenisher which has been cleaned by a microfiltration filter 9 of a venous drip chamber 4 attached to a venous circuit 3. An extracorporeal circuit 1 characterized in that an air trap 6 is provided at 18d. 2. The replenisher line 5a includes a clamp 17a,
The extracorporeal circuit 1 according to claim 1, wherein the extracorporeal circuit 1 includes an air trap 6, a rolling tube 27, and the injection line 18a includes a connector 24a and a clamp 17b. 3. The replenisher line 5b includes a clamp 17a,
The injection line 18b includes an air trap 6, a connection connector 24, and a connection connector 24a, a clamp 17
b. The extracorporeal circuit 1 according to claim 1, further comprising a rolling tube 27. 4. The replenisher line 5c includes a clamp 17a,
2. The extracorporeal circuit 1 according to claim 1, further comprising a connection connector 24, wherein the injection line 18 c includes a connection connector 24 a, a clamp 17 b, a rolling tube 27, and an air trap 6. 5. The replenisher line 5d includes a clamp 17a,
2. The extracorporeal circuit 1 according to claim 1, wherein the extracorporeal circuit 1 includes an air trap 6, a rolling tube 27, and a connector 24, and the injection line 18d includes a connector 24a, a clamp 17b, and the air trap 6.