JP3046275B2 - Non-invasive continuous blood pressure monitor - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a non-invasive continuous sphygmomanometer, and more particularly to a method for continuously inducing blood pressure by applying vibration to a blood vessel in a living body and detecting and analyzing the vibration propagated in the blood vessel. The present invention relates to a non-invasive continuous sphygmomanometer for performing continuous measurement.

[0002]

2. Description of the Related Art As a method of measuring blood pressure continuously and non-invasively, "Apparatus and Method for Measuring Physiological Parameters by Measuring Induced Perturbation" disclosed in Japanese Patent Publication No. Hei 9-506024. It has been known. FIG. 7 shows the appearance of this device. This device analyzes and tracks blood pressure, vascular wall compliance, ventricular contractility, vascular resistance, blood volume, cardiac output, myocardial contractility and many other physiological parameters. The device obtains periodic calibration measurements representing the patient's physiological parameters to continuously measure the patient's physiological parameters. An exciter is placed over the patient's artery to induce an oscillating wave in the arterial blood. A non-invasive sensor is placed on the artery to detect a vibration wave and obtain a signal representing a blood parameter. The processor is
The calibration measurements and non-invasive sensor signals are processed to continuously measure the patient's physiological parameters. This blood pressure measurement method utilizes the fact that the elasticity of a blood vessel changes according to a change in blood pressure, calculates the elasticity of a blood vessel by measuring the sound speed of a sound wave propagating through the blood vessel, and measures the blood pressure from the elasticity value of the blood vessel. doing.

[0003]

[Problems to be solved by the invention]
In the publication 9-506024, the vibration frequency of the exciter is
It only states that it is valid at all frequencies,
No specific oscillation method and frequency control method are described. In the non-invasive continuous sphygmomanometer, it is necessary to set the frequency and the amplitude to the optimum values, and it is necessary to keep the frequency and the amplitude accurately and stably. The conventional non-invasive continuous sphygmomanometer has a problem that it is difficult to set the frequency and the amplitude to the optimum values and to keep it stable. Also, blood pressure calculation
To input a phase detection reference signal for
The need for an excitation sensor increases the number of components in the device.
There was a problem that would.

An object of the present invention is to solve the above-mentioned conventional problems, and to provide a highly reliable and accurate non-invasive continuous blood pressure monitor capable of arbitrarily controlling the frequency and amplitude with a simple configuration. And

[0005]

In order to solve the above problems, the present invention provides a non-invasive continuous sphygmomanometer using a vibration oscillator using a processor operated or numerically controlled oscillator or a voltage controlled oscillator, and a vibration oscillator. An exciter that vibrates an artery in a living body from the body surface by the generated signal, a non-invasive sensor that converts the vibration given by the exciter and propagated on the artery into an electric signal, and absolute values of systolic blood pressure and diastolic blood pressure A blood pressure monitor for measuring the blood pressure, and a non-invasive blood pressure based on the dynamic pressure waveform calculated from the phase change of the signal detected by the non-invasive sensor based on the signal oscillated by the vibration oscillator and the measured value from the calibration blood pressure monitor And a blood pressure calculating unit for continuously calculating the blood pressure in the living body, and a blood pressure waveform display unit for displaying the continuous blood pressure waveform calculated by the blood pressure calculating unit.

With this configuration, it is possible to control at any frequency and amplitude that is most effective for the subject, and a highly reliable and accurate non-invasive continuous blood pressure monitor can be realized.

[0007]

DESCRIPTION OF THE PREFERRED EMBODIMENTS According to the first aspect of the present invention , data for oscillating at a desired frequency is calculated.
A processor and a method for recording an operation result of the processor;
Molly and the timing that the processor outputs data
A reference oscillator for providing a reference to the processor to the processor;
Data output from the processor is output from the reference oscillator.
According to the conversion timing signal
A D / A converter for generating an exciter signal;
Signal to remove unnecessary frequency components from the signal.
A vibration oscillator that can arbitrarily oscillate a signal of a frequency and an amplitude that is most effective for a subject; and an exciter that vibrates an artery in a living body from a body surface by a signal generated by the vibration oscillator. A non-invasive sensor that converts the vibration transmitted over the artery given by the exciter into an electric signal, a calibration sphygmomanometer that measures absolute values of systolic blood pressure and diastolic blood pressure, and a signal oscillated by the vibration oscillator Blood pressure calculating means for continuously calculating the in-vivo blood pressure in a non-invasive manner based on a dynamic pressure waveform calculated by a phase change of a signal detected by the non-invasive sensor and a measurement value from the calibration sphygmomanometer with reference to And a blood pressure waveform display unit that displays a continuous blood pressure waveform calculated by the blood pressure calculation means. Control to obtain a highly accurate vibration source with less spurious, vibrate the exciter at any frequency and amplitude that is most effective for the subject, and detect the phase change used by the exciter vibration source and blood pressure calculation means , Signals are simultaneously generated to enable highly reliable and accurate blood pressure measurement with a minimum circuit configuration, and to flexibly cope with differences between subjects.

[0008] The invention described in claim 2 is the first invention.
In the non-invasive continuous sphygmomanometer according to the above, the vibration oscillator is substituted.
For example in a numerically controlled oscillator, a reference oscillator providing a reference clock to the numerically controlled oscillator, the conversion of a processor that sets the frequency data into the numerical control oscillator, the output data from the numerical control oscillator from said reference oscillator Ta
A D / A converter into an analog signal to generate an exciter signal in accordance with timing signals, vibration onset with a filter for removing an unnecessary frequency component from the exciter signal
It is those in which a vibrator, an arbitrary frequency, can be obtained any vibration sources with high spurs of less accurate amplitude, also be obtained oscillation source of a high accuracy by using a numerically controlled oscillator Since the calculation load of the processor can be reduced, the blood pressure measurement can be performed at high speed.

[0009] The invention described in claim 3 is the first invention.
In the non-invasive continuous sphygmomanometer according to the above, the vibration oscillator is substituted.
For example, the processor for calculating the data for oscillating at a desired frequency, a memory for storing the operation result of the processor as a look-up table, a reference to provide a reference timing for outputting data from said processor to said processor An oscillator, an address generator for automatically generating an address of the memory for outputting data from the memory, and a conversion timing signal from the reference oscillator for converting data output from the memory.
A vibration oscillator comprising: a D / A converter that generates an exciter signal by converting the signal into an analog signal according to the following formula; and a filter that removes unnecessary frequency components from the exciter signal, It is possible to obtain a high-precision vibration source with little spurious at any frequency and any amplitude, and because the calculation of the processor is not performed in real time but calculated in advance and written to the lookup memory. , The processor load during measurement can be reduced,
It has the effect of enabling a flexible and high-speed blood pressure measurement with respect to differences between subjects.

[0010] The invention described in claim 4 is the first invention.
In the non-invasive continuous sphygmomanometer according to the above, the vibration oscillator is substituted.
For example, the set a reference oscillator for generating a reference signal of PLL, a voltage controlled oscillator that generates a exciter signal, a frequency divider for dividing the exciter signal, the frequency dividing ratio to be supplied to the frequency divider A processor, a phase comparator for comparing the phase of the signal divided by the frequency divider with the reference signal, an integrator for integrating a signal output from the phase comparator, and an unnecessary frequency from the exciter signal. It is provided with a vibration oscillator equipped with a filter for removing components, it is possible to obtain a high-precision vibration source with less spurious at any frequency and any amplitude, and by using a voltage-controlled oscillator Since a high-precision oscillation source can be obtained and the calculation load on the processor can be reduced, the blood pressure measurement can be performed at high speed.

Hereinafter, an embodiment of the present invention will be described with reference to FIG.
This will be described in detail with reference to FIGS.

(First Embodiment) A first embodiment of the present invention relates to a vibration oscillator capable of arbitrarily oscillating a signal having a frequency and an amplitude most effective for a subject, and a vibration oscillator. An exciter that vibrates an artery in a living body from the body surface by a signal generated by the body surface, a non-invasive sensor that converts the vibration given by the exciter and propagated on the artery into an electric signal, an absolute systolic blood pressure and a diastolic blood pressure A calibration sphygmomanometer that measures the value, a dynamic pressure waveform calculated based on the phase change of the signal detected by the noninvasive sensor based on the signal oscillated by the vibration oscillator, and a measurement value from the calibration sphygmomanometer. A non-invasive continuous sphygmomanometer comprising a blood pressure calculating means for continuously calculating in-vivo blood pressure with blood, and a blood pressure waveform display unit for displaying a continuous blood pressure waveform calculated by the blood pressure calculating means.

FIG. 1 is a block diagram showing a configuration of a non-invasive continuous blood pressure monitor according to a first embodiment of the present invention. In FIG. 1, a vibration oscillator 1 is an oscillator that can oscillate at an arbitrary frequency and amplitude that is most effective for a subject from several Hz to several thousand Hz. The vibration oscillated by the vibration oscillator 1 causes the exciter 2 to vibrate the arterial blood vessel of the subject. The non-invasive sensor 3 includes the exciter 2 transmitted through the arterial blood vessel of the subject.
It is a sensor that converts the vibration from the sensor into an electric signal. The calibration sphygmomanometer 4 is a sphygmomanometer that operates at appropriate time intervals or at any time to measure the absolute values of the systolic blood pressure and the diastolic blood pressure of the subject. Blood pressure calculation means 5
Is based on a signal generated by the vibration oscillator 1 and a known method based on the electric signal output from the non-invasive sensor 3 and the absolute values of the systolic blood pressure and the diastolic blood pressure output from the calibration sphygmomanometer 4. In accordance with, for example, Table 9-506024
The continuous blood pressure is calculated by the method disclosed in Japanese Patent Application Laid-Open Publication No. H10-26095. The blood pressure waveform display section 6 displays the continuous blood pressure waveform output from the blood pressure calculation means 5.

As described above, in the first embodiment of the present invention, the non-invasive continuous sphygmomanometer is generated by a vibration oscillator using an arithmetic or numerically controlled oscillator or a voltage controlled oscillator by a processor, and a vibration oscillator. Exciter that vibrates arteries in the living body from the body surface with the received signal, a non-invasive sensor that converts the vibration given by the exciter and propagated over the artery into an electric signal, and measures the absolute values of systolic and diastolic blood pressure The blood pressure monitor for calibration, and the non-invasive continuous blood pressure based on the dynamic pressure waveform calculated from the phase change of the signal detected by the non-invasive sensor based on the signal oscillated by the vibration oscillator and the measurement value from the calibration blood pressure monitor A blood pressure calculating means for calculating the blood pressure in the living body, and a blood pressure waveform display unit for displaying the continuous blood pressure waveform calculated by the blood pressure calculating means. Can be controlled at any frequency and amplitude as the most effective Te, accurate noninvasive continuous blood pressure monitor can be realized with high reliability.

(Second Embodiment) In a second embodiment of the present invention, as a vibration oscillator, a processor for calculating data for oscillating at a desired frequency, and a memory for recording a calculation result of the processor are provided. A reference oscillator for giving the processor a timing of outputting data to the processor, a D / A converter for converting data output from the processor to an analog signal to generate an exciter signal, It is a non-invasive continuous sphygmomanometer provided with a filter for removing a frequency component.

FIG. 2 is a block diagram showing a configuration of a non-invasive continuous blood pressure monitor according to a second embodiment of the present invention. In FIG. 2, the exciter 2, the non-invasive sensor 3, the calibration sphygmomanometer 4, the blood pressure calculating means 6, and the blood pressure display unit 6 have the same functions as those described in the first embodiment. is there.

Hereinafter, a description will be given of the vibration oscillator 1 using the oscillation method based on the calculation of the processor. Processor 10
It is an interrupt signal generated by the reference oscillator 12 as a timing, thus calculates the oscillation data calculation. The memory 11 is used as an operation result of the processor 10 and a work memory. The reference oscillator 12 includes a reference signal 15 for generating an interrupt to the processor at regular intervals, and a conversion timing signal for controlling the conversion timing to the D / A converter 13.
Generates 16. The D / A converter 13 performs digital / analog conversion of the oscillation data calculated by the processor 10. The filter 14 removes unnecessary frequency components from the analog output of the D / A converter 13 and supplies a signal with less spurious to the exciter 2, thereby enabling highly accurate blood pressure measurement.

The output from the filter 14 is input to the blood pressure calculating means 5 and used as a reference signal for detection for calculating the blood pressure. The processor 10 and the blood pressure calculating means 5 may be the same device.

A preferred method of calculating the oscillation data in the processor 10 is a double integration method. Although the double integration method is a known method, a preferred method in the second embodiment will be described with reference to FIG. Reference oscillator 12
Corresponds to the reference oscillator shown in FIG. 2 and generates an oscillation reference signal 15. The process is started with the reference signal 15 as a trigger.

Two types of integrators, a first integrator 50 and a second integrator 52, and an inverting amplifier 51 having a gain of 1 are connected in series.
It is configured to form a loop. The first integrator 50 includes a delay unit 56, a multiplier 57, and an adder 53.
The data is delayed by one sampling, and the adder 53
The output of the multiplier 60 in the second integrator 52, the output of the delay unit 56, and the reference signal 15 are added. The data added by the adder 53 is output as a cos output 55. Multiplier 57
The s output 55 is multiplied by an arbitrary coefficient a. Also, the second
The integrator 52 includes a delay unit 59, a multiplier 60, and an adder 58. The delay unit 59 delays data by one sampling. The adder 58 outputs the output of the delay unit 59 and the output of the inverting amplifier 51. And outputs the result as a sine output 54. The multiplier 60 is
The output of the delay unit 59 is multiplied by an arbitrary coefficient a. FIG.
The reference oscillator 12 indicated by generates a reference signal 15 for oscillation. The arithmetic circuit operates at the frequency of the reference signal 15. The trigger generator 61 generates a trigger pulse for starting oscillation, and the trigger pulse starts oscillation.

With such a configuration, a sine wave of an arbitrary frequency can be obtained by changing the coefficient a of the multiplier.
The frequency f is f = (a × T) / (2 × π) (where π: pi (3.1415...)), And T: the frequency of the reference signal 15 generated by the reference oscillator 12 Operating frequency).

By performing the processing described above, the oscillation frequency of the vibration oscillator can be easily changed by changing the coefficient a of the multiplier. In addition, the sine output 54 and the cosine output 55 having a 90-degree phase difference necessary for detecting a phase change in the blood pressure calculating means 5 can be simultaneously obtained.

As described above, in the second embodiment of the present invention, a processor for calculating data for causing a non-invasive continuous blood pressure monitor to oscillate at a desired frequency as a vibration oscillator, and a calculation result of the processor. A D / A converter for converting the data output from the processor into an analog signal to generate an exciter signal, Since the filter is provided with a filter for removing unnecessary frequency components from the device signal, two reference signals, sin and cos, which can easily change the oscillation frequency with high accuracy can be obtained at the same time.

(Third Embodiment) In a third embodiment of the present invention, as a vibration oscillator, a numerically controlled oscillator, a reference oscillator for providing a reference clock to the numerically controlled oscillator, and frequency data to the numerically controlled oscillator A processor for setting, and a D / D converter for converting data output from the numerically controlled oscillator into an analog signal to generate an exciter signal
This is a non-invasive continuous blood pressure monitor including an A converter and a filter for removing unnecessary frequency components from an exciter signal.

FIG. 3 is a block diagram showing a configuration of a non-invasive continuous sphygmomanometer according to a third embodiment of the present invention. In FIG. 3, the exciter 2, the non-invasive sensor 3, the calibration sphygmomanometer 4, the blood pressure calculating means 5, and the blood pressure display unit 6
It has functions similar to those described in the first embodiment.

Hereinafter, the vibration oscillator 1 using the numerically controlled oscillator will be described. Processor 20 is a numerically controlled oscillator
Give data corresponding to the frequency to be oscillated to 21.
The numerically controlled oscillator 21 uses the signal from the reference oscillator 22 as a reference, and
The digital data of n and the digital data of cos 90 degrees out of phase are output. The D / A converter 23 converts the data output from the numerically controlled oscillator 21 from analog to digital. Filter 24 is D / A and filter 24
Is input to the blood pressure calculating means 5 and used as a reference signal for detection for calculating the blood pressure. The processor 20 and the blood pressure calculation means 5 may be the same device.

According to the method described above, oscillation can be performed at an arbitrary frequency and an arbitrary amplitude, and a vibration source with less spurious and high accuracy can be obtained. In addition, by using a numerically controlled oscillator, a high-precision oscillation source can be obtained and the calculation load of the processor can be reduced, so that blood pressure measurement can be performed at high speed.

As described above, in the third embodiment of the present invention, a non-invasive continuous sphygmomanometer is used as a vibration oscillator, a numerically controlled oscillator, a reference oscillator that supplies a reference clock to the numerically controlled oscillator, and a numerically controlled oscillator. A processor for setting frequency data in an oscillator, and a D / A for converting data output from the numerically controlled oscillator into an analog signal to generate an exciter signal
Since the configuration is provided with the converter and the filter that removes unnecessary frequency components from the exciter signal, it is possible to obtain high-precision vibration with little spurious at any frequency and amplitude. Further, since the calculation load of the processor can be reduced, blood pressure measurement can be performed at high speed.

(Fourth Embodiment) In a fourth embodiment of the present invention, as a vibration oscillator, a processor for calculating data for oscillating at a desired frequency, and a calculation result of the processor as a look-up table. A memory for storing, a reference oscillator for giving the processor a reference for timing of outputting data from the processor, an address generator for automatically generating an address of the memory for outputting data from the memory, and a memory for outputting data from the memory. A non-invasive continuous sphygmomanometer comprising a D / A converter for converting the converted data into an analog signal to generate an exciter signal, and a filter for removing unnecessary frequency components from the exciter signal.

FIG. 4 is a block diagram showing a configuration of a non-invasive continuous blood pressure monitor according to a fourth embodiment of the present invention. In FIG. 4, the exciter 2, the non-invasive sensor 3, the calibration sphygmomanometer 4, the blood pressure calculating means 5, and the blood pressure display unit 6 have the same functions as those described in the first embodiment. is there.

Here, an oscillation method using a lookup table in the vibration oscillator 1 will be described. The processor 30 calculates data corresponding to the frequency and amplitude to be oscillated in advance, and writes the result to the look-up table memory 31. The reference oscillator 32 generates a reference signal to the address generator 23 as a reference for address generation. The address generator 23 generates an address of the look-up table memory based on the reference signal output from the reference generator 32. According to this address, the oscillation data is sequentially read from the look-up memory 31. The D / A converter 34 performs digital / analog conversion of the oscillation data output from the lookup memory 31. The filter 35 removes unnecessary frequency components of the analog output of the D / A converter 34,
By providing a signal with less spurious to the exciter 2, highly accurate blood pressure measurement can be performed.

The output from the filter 35 is input to the blood pressure calculating means 5 and is used as a reference signal for detection for calculating the blood pressure. The processor 30 and the blood pressure calculation means 5 may be the same device.

According to the method described above, it is possible to obtain a high-precision vibration source having a small spurious value at an arbitrary frequency and an arbitrary amplitude. Since the data is written in the up memory, the load on the processor during measurement can be reduced. Therefore, the blood pressure can be measured flexibly and at high speed with respect to the difference between the subjects.

As described above, in the fourth embodiment of the present invention, a processor for calculating data for causing a non-invasive continuous blood pressure monitor to oscillate at a desired frequency as a vibration oscillator, and a calculation result of the processor And a reference oscillator that provides the processor with a timing reference for outputting data from the processor, and an address generator that automatically generates an address of the memory to output data from the memory. And a D / A converter for converting data output from the memory into an analog signal to generate an exciter signal, and a filter for removing unnecessary frequency components from the exciter signal. High frequency and low amplitude spurious vibrations can be obtained, and the processor load during measurement is light. Since it can flexible and fast blood pressure measurement to the difference in the subject.

(Fifth Embodiment) In a fifth embodiment of the present invention, a vibration oscillator
A reference oscillator for generating an L reference signal, a voltage-controlled oscillator for generating an exciter signal, a frequency divider for dividing the exciter signal, and a processor for setting a frequency division ratio given to the frequency divider;
A phase comparator for comparing the phase of the signal divided by the frequency divider with the reference signal, an integrator for integrating the signal output from the phase comparator, and a filter for removing unnecessary frequency components from the exciter signal. It is a non-invasive continuous sphygmomanometer equipped.

FIG. 5 is a block diagram showing a configuration of a non-invasive continuous sphygmomanometer according to a fifth embodiment of the present invention. In FIG. 5, the exciter 2, the non-invasive sensor 3, the calibration sphygmomanometer 4, the blood pressure calculating means 5, and the blood pressure display unit 6 have the same functions as those described in the first embodiment. It is.

Here, an oscillation method using a phase locked loop (PLL) in the vibration oscillator 1 will be described. The reference oscillator 40 generates a reference signal of the PLL.
The voltage controlled oscillator 45 oscillates with a voltage corresponding to the phase difference output from the integrator 43. The phase comparator 42 detects a phase difference between the reference signal from the reference oscillator 40 and the frequency-divided signal from the frequency divider 44. The integrator 43 integrates the phase difference signal from the phase comparator 42. The frequency divider 44 divides the frequency of the oscillation signal of the voltage controlled oscillator 45 according to the frequency division ratio arbitrarily set by the processor 41. The filter 46 removes unnecessary frequency components from the analog output of the voltage-controlled oscillator 45 and supplies a signal with less spurious to the exciter 2, thereby enabling highly accurate blood pressure measurement.

The output from the filter 14 is input to the blood pressure calculating means 5 and used as a reference signal for detection of blood pressure. The processor 10 and the blood pressure calculating means 5 may be the same device.

According to the above-described method, an arbitrary frequency can be easily oscillated by changing data supplied from the processor 41 to the frequency divider 44, and a vibration source with an arbitrary amplitude, a small spuriousness and a high accuracy can be obtained. it can. In addition, by using a voltage-controlled oscillator, a high-precision oscillation source can be obtained, and the calculation load on the processor can be reduced, so that blood pressure measurement can be performed at high speed.

As described above, in the fifth embodiment of the present invention, the non-invasive continuous sphygmomanometer is used as a vibration oscillator and a PLL.
A reference oscillator that generates a reference signal, a voltage-controlled oscillator that generates an exciter signal, a divider that divides the exciter signal, a processor that sets a division ratio given to the divider, and a reference signal. A configuration including a phase comparator that compares the phases of the signals divided by the frequency divider, an integrator that integrates the signal output from the phase comparator, and a filter that removes unnecessary frequency components from the exciter signal Therefore, it is possible to easily obtain high-precision vibration with little spurious at an arbitrary frequency and amplitude, and to reduce the calculation load of the processor, so that the blood pressure measurement can be performed at high speed.

[0041]

As described above, according to the present invention, a non-invasive continuous blood pressure monitor can be controlled by a vibration oscillator using a processor or a numerically controlled oscillator or a voltage controlled oscillator, and a signal generated by the vibration oscillator. An exciter that vibrates arteries in the living body from the table, a non-invasive sensor that converts the vibration given by the exciter and transmitted on the artery into an electrical signal, and a calibration device that measures the absolute values of systolic and diastolic blood pressure A blood pressure monitor and a dynamic pressure waveform calculated from a phase change of a signal detected by a non-invasive sensor with reference to a signal oscillated by a vibration oscillator and a measurement value from a calibration sphygmomanometer continuously in vivo in a non-invasive state. The blood pressure calculating means for calculating the blood pressure of the subject, and the blood pressure waveform display section for displaying the continuous blood pressure waveform calculated by the blood pressure calculating means. Can be controlled at any frequency and amplitude as a, the effect is obtained that highly accurate noninvasive continuous blood pressure monitor can be realized with high reliability.

Also, the oscillator of the exciter signal in the sphygmomanometer that measures non-invasively and continuously is constructed using a processor operated or a numerically controlled oscillator or a voltage controlled oscillator, and the oscillation frequency and amplitude of the exciter can be arbitrarily set. By setting and outputting an oscillation signal with less spurious, the exciter can be oscillated at the optimal frequency for the subject, and the oscillated signal is also used as a reference signal for detecting a phase change in blood pressure calculation. Therefore, the accuracy and reliability of blood pressure measurement can be significantly improved with a minimum configuration.

[Brief description of the drawings]

FIG. 1 is a block diagram of a non-invasive continuous blood pressure monitor according to a first embodiment of the present invention;

FIG. 2 is a block diagram of a non-invasive continuous blood pressure monitor according to a second embodiment of the present invention;

FIG. 3 is a block diagram of a non-invasive continuous blood pressure monitor according to a third embodiment of the present invention;

FIG. 4 is a block diagram of a non-invasive continuous sphygmomanometer according to a fourth embodiment of the present invention;

FIG. 5 is a block diagram of a non-invasive continuous sphygmomanometer according to a fifth embodiment of the present invention;

FIG. 6 is a block diagram of a double integration circuit used for a non-invasive continuous blood pressure monitor according to a second embodiment of the present invention;

FIG. 7 is an external view of a conventional non-invasive continuous blood pressure monitor.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Vibration oscillator 2 Exciter 3 Non-invasive sensor 4 Calibration sphygmomanometer 5 Blood pressure calculation means 6 Blood pressure waveform display unit 10 Processor 11 Memory 12 Reference oscillator 13 D / A converter 14 Filter 15 Reference signal 16 Conversion timing signal 20 Processor 21 Numerically Controlled Oscillator 22 Reference Oscillator 23 D / A Converter 24 Filter 30 Processor 31 Look-Up Table Memory 32 Reference Oscillator 33 Address Generator 34 D / A Converter 35 Filter 40 Reference Oscillator 41 Processor 42 Phase Comparator 43 Integrator 44 Divider 45 Voltage controlled oscillator 46 Filter 50 First integrator 51 Inverting amplifier 52 Second integrator 53 Adder 54 Sin output 55 Cos output 56 Delayer 57 Multiplier 58 Adder 59 Delayer 60 Multiplier

────────────────────────────────────────────────── ─── Continuation of the front page (56) References JP-A-8-256998 (JP, A) JP-A-4-250135 (JP, A) JP-A-3-118045 (JP, A) Table 9- 506024 (JP, A) (58) Field surveyed (Int. Cl. ⁷ , DB name) A61B 5/022-5/0295 A61B 8/04

Claims (4)

(57) [Claims] 1. Data for oscillating at a desired frequency
And a calculation result of the processor
A memory for recording, and the processor outputs data.
Reference oscillation for providing a timing reference to the processor
And the data output from the processor as the reference
Analog signal according to conversion timing signal from oscillator
A D / A converter that converts the signal into an exciter signal to generate
Filter for removing unnecessary frequency components from exciter signals
And a vibration oscillator capable of arbitrarily oscillating a signal of a frequency and an amplitude most effective for the subject, and vibrating an artery in a living body from a body surface by a signal generated by the vibration oscillator. An exciter, a non-invasive sensor that converts the vibration transmitted on the artery given by the exciter into an electric signal, a calibration sphygmomanometer that measures absolute values of systolic blood pressure and diastolic blood pressure, and the vibration oscillator A non-invasive blood pressure is continuously calculated in a living body based on a dynamic pressure waveform calculated by a phase change of a signal detected by the non-invasive sensor based on the oscillated signal and a measurement value from the calibration sphygmomanometer. A non-invasive continuous sphygmomanometer, comprising: a blood pressure calculating unit; and a blood pressure waveform display unit that displays a continuous blood pressure waveform calculated by the blood pressure calculating unit. 2. A numerically controlled oscillator, a reference oscillator for providing a reference clock to the numerically controlled oscillator, a processor for setting frequency data to the numerically controlled oscillator, and a signal output from the numerically controlled oscillator instead of the oscillation oscillator. Data in accordance with the conversion timing signal from the reference oscillator.
D / to convert to an analog signal to generate an exciter signal
2. The non-invasive continuous sphygmomanometer according to claim 1, further comprising a vibration oscillator including an A converter and a filter for removing unnecessary frequency components from the exciter signal. 3. A processor for calculating data for oscillating at a desired frequency in place of the vibration oscillator , a memory for storing a calculation result of the processor as a look-up table, and outputting data from the processor. A reference oscillator for providing a timing reference to the processor, and for outputting data from the memory,
The group address generator for automatically generating an address of said memory, the data output from said memory
A D / A converter for converting an analog signal according to a conversion timing signal from the quasi-oscillator to generate an exciter signal;
The non-invasive continuous sphygmomanometer according to claim 1, further comprising a vibration oscillator including a filter that removes unnecessary frequency components from the exciter signal. 4. A reference oscillator for generating a PLL reference signal instead of the oscillation oscillator , a voltage controlled oscillator for generating an exciter signal, a frequency divider for dividing the exciter signal, and the frequency divider A processor for setting a frequency division ratio given to the frequency divider, a phase comparator for comparing the phase of the signal divided by the frequency divider with the reference signal, and an integrator for integrating a signal output from the phase comparator. the vibration oscillator and a filter for removing an unnecessary frequency component from the exciter signal
Noninvasive continuous blood pressure meter according to claim 1, characterized in that provided.