JP3033836B2 - Multi-chamber medical bag - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Application Field] The present invention relates to a polyolefin-based medical bag having two or multiple chambers, and is easy to handle when mixing two liquids immediately before use. It is intended to provide a medical bag with excellent hygiene and flexibility.

[Conventional technology]

Recently, the amount of medical liquid containers, particularly soft bags having flexibility, has been increasing in terms of safety and ease of use. In this method, two liquids are separately combined by a Y-tube immediately before use, and a method of instilling the liquid has been used. However, in terms of handling and safety, the two liquids are placed in separate chambers in one bag. There has been a strong demand for a medical bag having two chambers or multiple chambers in which two liquids are easily mixed and integrated immediately before use before use. However, a method of separating two liquids in the same bag includes a method of pressing the bag with a clamp or the like from the outside of the bag to separate the liquid (to form two chambers), or a method of separating the two liquids.
A method has been mainly used in which a liquid is fused to a chamber, a connector is attached to a fused portion, and when used, the connector is opened to mix the two liquids.

Each method has its advantages and disadvantages, and the method of clamping from the outside of the bag has a risk that if the clamp is loosened due to some influence, the two liquids may mix little by little without knowing. However, in the clamp method, the two liquids can be easily mixed by removing the clamp, and at the same time, it is possible to mix the two liquids in a short time by increasing the width of the clamp, which is convenient.

On the other hand, in the method of attaching a connector and separating the bag into two chambers by fusing, the two liquids are easily mixed as long as the connector does not come off, unlike the previous clamping method, because the bag is fused including the connector. It is hard to imagine the matter, so it was safe for long-term storage. However, in this method, the passage for mixing the two liquids is only the connector portion, and is greatly influenced by the performance of the connector. In particular, since two liquids are mixed through this connector, it takes more time to mix than the clamp method, and depending on the type of connector, the connector that breaks and connects this part may have connector fragments mixed into the liquid. There was a problem.

[Problems to be solved by the invention]

SUMMARY OF THE INVENTION An object of the present invention is to overcome the problems of each of the above two conventional techniques while taking advantage of the respective advantages.

In other words, a two-solution having the function of easily mixing the two solutions in the clamp system in a short time and the advantage of no leakage and high safety by fusing the bag of the connector system to separate the two solutions. Is to provide a separation method.

[Means for solving the problem]

As a result of intensive studies to solve the above problems,
"At the boundary part separating the two liquids, the peel strength of at least the interface between the two layers of the multilayer is fused to the bag film via a multilayer film having a strength of 300 to 800 g / 15 mm. It has been found that the above problem can be solved by a "medical bag having multiple chambers," and the present invention has been completed.

A feature of the present invention is that a wide multilayer film is used for a connector portion of a medical bag (hereinafter abbreviated as a bag), and a partial interface in the multilayer film has a peel strength of 300 to 800 g / 15 mm. Having the strength of

Peel strength is required to be 300 g / 15 mm or more. Below this, peeling occurs due to slight impact during transportation, and the two liquids are mixed. More preferably, it is 400 g / 15 mm or more.

That is, as an example, in the multilayer film as shown in FIG. 1, the peel strength at the interface between the layer A and the layer B is set to 300 to 800 g / 15 mm, and the multilayer film is placed between two bag films as shown in FIG. By sandwiching and strongly fusing the two bag films to the A layer and the C layer of the multilayer film, a boundary portion separating one bag into two chambers is formed.

At this time, as shown in FIGS. 2 and 3, both ends of the multilayer film need to be sealed so as to protrude into the respective chambers from a sealing line at the time of heat sealing with the bag film. Without this protruding portion, if an internal pressure is applied to the liquid in the P chamber or the Q chamber, separation easily occurs between the A layer and the B layer. However, if this protruding portion is 10 mm or more, even if internal pressure is applied to each chamber, stress concentrates on the seal line portion between the bag film and the multilayer film, so that peeling does not occur between A and B of the multilayer film, Excellent separation performance can be exhibited.

On the other hand, when the two liquids are mixed, they can be peeled off relatively easily by applying a stimulus to the multilayer film from outside the bag or by applying a strain to the heat seal portion from the outside.

As an example, as shown in FIG. 2, by pulling up and down the protrusion tabs provided on both sides of the bag film by hand, the interface (for example, between AB) of the multilayer film is peeled off, and P
The two liquids of the chamber and the Q chamber can be easily mixed.

Although the present invention has been described with reference to the example of a double bag that separates two liquids, the present method is provided in various places in the bag to reduce
The present invention can also be applied to a multi-compartment bag for separating liquid and liquid.

As a material for the multilayer film, a polyolefin-based material having high safety, which is approved for medical use, is preferable, and a single material or a blend of low-density polyethylene, linear low-density polyethylene, high-density polyethylene, and polypropylene can be used.

In the production of the multilayer film, for example, a co-extrusion molding method can be adopted, and the composition of each layer may be selected so that the peel strength between the interfaces of the layers is in the range of 300 to 800 g / 15 mm.

On the other hand, since a bag film usually uses a polyolefin-based material, it is necessary to select a composition that strongly fuses with the bag film on both outer surfaces of the multilayer film.

Specifically, layer B of the intermediate layer is a copolymer of polypropylene, and layers A and C on both sides are linear low-density polyethylene. Alternatively, a combination in which the intermediate layer B is made of a blend of polypropylene and polyethylene and the layers A and C are made of polyethylene or a blend of polyethylene and polypropylene can be exemplified.

Hereinafter, the present invention will be described more specifically with reference to Examples, but the present invention is not limited to Examples.

〔Example〕

An example of a three-layer structure of A, B and C as shown in FIG. 1 will be described as an example of a multilayer film.

Using three extruders with a screw diameter of 50 mm, using a three-layer T-die (width: 300 mm) with a lip gap of 3.0 mm,
Three-layer film (A / B / C) with a thickness of 600μ by chill roll method
= 200μ / 200μ / 200μ). The resin of each of the layers A, B and C had the following physical properties.

Peel strength at the interface between A and B of this three-layer film (JIS Z170
7) was 550 g / 15 mm.

The obtained three-layer film is cut into an appropriate size,
As shown in FIG. 3 and FIG. 3, heat sealing is performed along the seal line by inserting the medical bag made of polyethylene into the interface between the P chamber and the Q chamber.

The double bag thus obtained is filled with different chemicals in the P and Q chambers, transported and stored, but no mixing of the two liquids was recognized even after 6 months.

Further, at the time of use, by pulling the two projection tabs shown in FIG. 2 by hand, the interface between A and B was disengaged, and the chemicals in the P and Q chambers could be mixed quickly.

〔The invention's effect〕

The multi-chamber medical bag of the present invention is excellent in safety because there is no possibility of leakage of the chemical solution between the respective rooms during transportation or storage, and in use, each room can be easily operated. Excellent effect that liquid can be mixed promptly.

[Brief description of the drawings]

FIG. 1 is an example of the configuration of a multilayer film, FIG. 2 is a cross-sectional view of a two-chamber (P, Q) bag, and FIG. 3 is two-chamber (P, Q).
FIG. 3 shows a plan view of the bag. DESCRIPTION OF SYMBOLS 1 ... Multilayer film (three-layer film) 2 ... P room part of a two-room bag 3 ... Q room part of a two-room bag 4 ... Protrusion tab 5 ... P room side plug 6 ... Q room side mouth Plug 7: Heat-sealed part at boundary between two liquids 8: Seal line between bag film and multilayer film 9: Plug seal at room P 10: Plug seal at room Q

Claims (1)

(57) [Claims] At a boundary portion separating two liquids, the peel strength of an interface between at least two of the multilayers is 300 to 800.
A multi-chamber medical bag, wherein both ends of the multilayer film are fused to the bag film via a multilayer film having a strength of g / 15 mm such that both ends of the multilayer film protrude into the respective chambers from a sealing line.