JP3005091B2 - Food and drink that improves carbohydrate metabolism - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention regulates the mobilization of blood glucose, especially when performing aerobic exercises in a broad sense, including exercises requiring endurance and labor requiring repeated muscular exertion. In addition, the present invention relates to a food and drink containing a Reishi component having an effect of increasing the concentration of glycogen in muscle during consumption and reducing the amount of lactic acid in blood to improve the metabolism of carbohydrate.

[0002]

2. Description of the Related Art Reishi as a food or drink is used as a so-called "health food" or for a specific medical purpose, for example, improvement of cholesterol level in hyperlipidemia, prevention of arteriosclerosis, hypotensive action, elevated blood pressure. It has been used for the purpose of action, improvement of diabetes, suppression of gallstones, prevention of colorectal cancer, improvement of senile dementia, improvement of liver dysfunction and the like.

[0003]

The present inventors have been studying the efficacy of Reishi from the viewpoint of improving carbohydrate metabolism from various angles, in addition to the above-mentioned effects. As a result of repeated studies of carbohydrate metabolism during exercise, especially the effect of increasing the amount of glycogen by supplementing the decrease in the amount of glycogen in muscle cells and the effect of suppressing the accumulation of lactate in the blood, It has been found that it is possible to provide a food and beverage containing a reishi ingredient having an effect of improving metabolism.

[0004]

The food and drink for improving carbohydrate metabolism according to the present invention contains a Ganoderma ingredient and promotes the recruitment and renewal of sugar from the liver during prolonged exercise, as well as glycogen in muscle. It has the effect of replenishing the consumption of lactic acid and the effect of suppressing the production of blood lactic acid.

[0005]

[Functions] Carbohydrates taken into the human body are decomposed into glucose through various pathways by the action of enzymes in the body, and this glucose enters the portal vein through the capillaries and is transported to the liver, where glycogen and fats are absorbed. Is synthesized. Some of the glycogen diffuses into the blood to form blood sugar, and some is carried to muscles and contributes to the generation of kinetic energy. When the exercise is mild, glucose is mobilized from the liver in response to the glycogen depletion in the muscle, but during heavy exercise the glucose mobilization is insufficient. The food and beverage containing the reishi component of the present invention is involved in such carbohydrate metabolism during intense exercise and improves it.

[0006] The food or drink of the present invention does not matter whether it is liquid or solid, but it is essential that the food or drink contain a reishi component. The reishi component may be in the form of only the umbrella portion or the whole fruit body, and may be in the form of a crushed product or an extract. The most typical one contains Ganoderma extract, and according to the results of examination of Ganoderma extract, as shown in the experimental examples described below, an increase in blood glucose during running exercise, an increase in muscle glycogen and It showed a decrease in blood lactate concentration. These indicate that the reishi component was effective in improving carbohydrate metabolism when performing the aerobic exercise in a broad sense as described above.

[0007]

EXAMPLE The food and drink for improving carbohydrate metabolism containing the Ganoderma component according to the present invention may contain reduced maltose, oligosaccharides, folic acid, vitamin C, vitamin B ₁₂ , iron and the like in addition to the Ganoderma component. Possible and most typical are drinks. For example, in 100 ml of the reishi drink of the present invention, reishi extract (10% hot water extraction) 75-90 ml reduced maltose 5-5.5 ml oligosaccharide 2.5-3.5 ml folic acid 1-2.5 ml vitamin C 1-2.5 vitamin B ₁₂ 1-2.5 ml Contains iron 1-2.5 ml.

[0008]

[Experimental example] Mice and rats were used as experimental animals.
As a running test method, a treadmill running device (a device that applies an electric shock behind the rotating belt is provided,
The animals on the belt were forced to run in accordance with the movement of the belt), and the test animals were forced to run until they fell down, and the running distance was measured. Mild running training was performed for 8 weeks with free access to Ganoderma drink (0.25% and 0.5% concentration) or tap water (control), and then forced running using the treadmill device described above. . The amount of glycogen in the muscle cells and the amount of lactate in the blood during the process until the vehicle became unable to run were measured.
That is, a mouse was run on a treadmill at a speed of 35 m / min, and a rat was run on a treadmill at a speed of 45 m / min, and the load until exhaustion and running became impossible was determined, and the blood glucose amount, muscle glycogen amount and blood lactate amount at that time were measured. . In addition, 30 days from the start of this running test
Minutes, 60 minutes and 90 minutes were also measured.

[0009] First, the change in blood glucose was examined.
4 (0.25% administration group) and the results shown in Tables 5 to 8 (0.5% administration group) were obtained. Tables 1, 2, 5 and 6 show data of rats (female and male), and Tables 3, 4 and 7
And Table 8 shows the data of mice (female and male). In all cases, the running time was longer in the group administered with the reishi drink than in the group administered with tap water. It shows a high blood sugar level, indicating that the reishi component significantly improves carbohydrate metabolism.

[0010]

[Table 1]

[0011]

[Table 2]

[0012]

[Table 3]

[0013]

[Table 4]

[0014]

[Table 5]

[0015]

[Table 6]

[0016]

[Table 7]

[0017]

[Table 8]

Next, glycogen in muscle was examined.
The data in Tables 9 and 10 (0.25% administration group) and Tables 11 and 12 (0.5% administration group) were obtained. Tables 9 and 11 show the gastrocnemius muscle of the rat,
Tables 10 and 12 show the gastrocnemius muscles of the mice. Regardless of which the running time was increased, the amount of glycogen in the muscle in the group treated with Reishi drink was significantly higher than that in the group treated with tap water. It turns out that it shows a value.

[0019]

[Table 9]

[0020]

[Table 10]

[0021]

[Table 11]

[0022]

[Table 12]

[0023] Finally, the blood lactate content was examined.
4 (0.25% administration group) and Tables 15, 16 (0.5% administration group) were obtained. Tables 13 and 15 show rats, and Tables 14 and 16 show mice. It turns out that it is significantly lower than that.

[0024]

[Table 13]

[0025]

[Table 14]

[0026]

[Table 15]

[0027]

[Table 16]

According to the result of the forced running test under the same conditions, the group trained on the treadmill while drinking tap water and the group trained similarly while drinking the drink are shown in FIG. In the drink group, the blood glucose level was clearly higher, the blood level of lactic acid, a fatigue substance, decreased, and the consumption of glycogen in the muscle was small. Treadmill running is different from spontaneous running and is an aerobic exercise that is forced to run, so it is possible that glycogen resynthesis was stimulated by Reishi during running. It is considered that lactic acid is partially decomposed by oxygen and partially contributed to glycogen resynthesis.

[0029]

Since the present invention is configured as described above, it can be used by workers who use the whole body continuously, as well as sportsmen who participate in games, that is, those who repeatedly contract and relax muscles continuously. Provided is a food or drink that can replenish glycogen consumption in muscle cells in aerobic exercise as it progresses, suppress the production of blood lactic acid, and improve carbohydrate metabolism. It became.

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Claims (1)

(57) [Claims] 1. A respiratory tract containing a reishi component, which promotes the degradation of hepatic stored glycogen against hypoglycemia caused by prolonged exercise,
A carbohydrate metabolism-improving food or drink having an action of promoting sugar mobilization in blood, an action of supplementing glycogen into muscle, and an action of suppressing lactic acid production in blood.