JP2882650B2 - Semi-solid drug applicator - Google Patents

Description

Description: TECHNICAL FIELD The present invention relates to a semi-solid drug container filled with a semi-solid drug such as an ointment or a cream. In particular, the present invention relates to a semi-solid drug application device that can directly apply a semi-solid drug.

[Prior art] Conventionally, as a container for filling a semi-solid substance such as a semi-solid drug, a small-diameter screw portion is formed at an opening at one end, and the opening can be opened and closed by screwing a cap, and the other end is flattened. Pressed and closed cylindrical metal containers were commonly used.

However, in such a conventional semi-solid drug container, the amount of semi-solid drug used multiple times is filled,
The semi-solid drug cannot be applied directly to the affected area using the semi-solid drug container, and therefore, the finger is brought into contact with the opening of the semi-solid drug container, the semi-solid drug is applied to the finger, and then applied to the affected area. Was. For this reason, there is a risk of secondary infection and a risk of contamination of the opening of the semisolid drug container.

Therefore, there has been a demand for a semi-solid drug container which is suitable for filling the amount of the semi-solid drug required for one application and which can perform the coating operation easily and hygienically.

To satisfy the above requirements,
There is one disclosed in Japanese Patent No. 39231.

[Problems to be Solved by the Invention] The semi-solid drug container disclosed in the above-mentioned publication has a semi-solid drug container formed by a flexible pad provided around an opening of the container or an opening piece that closes the opening. It is configured to perform application, and also has a sufficient effect in this semi-solid medicine container. However, the opening piece covers only the vicinity of the opening, and when applying the semi-solid drug to the affected area,
The semi-solid drug adheres to the portion that was not covered by the opened piece, and the application to the affected area is performed also in this portion. In addition, the portion that is not covered with the opened piece may not be completely sanitary because bacteria and the like may be attached.

Therefore, an object of the present invention is to provide a semi-solid medicine container suitable for filling the amount of semi-solid medicine necessary for one application and capable of performing the application work easily, reliably and hygienically. Things.

[Means for Solving the Problems] To achieve the above object, there are provided an applicator main body, a semi-solid drug applying member fixed to one surface of the applicator main body, and a member attached to the applying member surface. A semi-solid drug, comprising a protective sheet for protecting the semi-solid drug adhering surface of the applicator body, the protective sheet includes a semi-solid drug adherence suppressing substance application portion partially applied to the inner surface, The semi-solid drug adhesion suppressing substance application section is in contact with the semi-solid drug and covers the surface of the semi-solid drug, and further, the applicator body and the protection sheet are provided with the semi-solid drug application member. The protective sheet is a semi-solid drug application device which is fixedly attached to an endless fixing portion provided so as to surround it, and which can be peeled off from the applicator body.

The protective sheet preferably has an adhesive resin layer and a gas barrier film layer provided below the adhesive resin layer. Further, it is preferable that the protective sheet has a peeling start portion for peeling the protective sheet. Furthermore, it is preferable that the member for applying a semi-solid drug is formed of a material having a soft feel with little absorption of the semi-solid drug. The applicator body may have a concave portion, and the semisolid drug applying member is attached to the concave portion. The member for applying the semi-solid drug is a nonwoven fabric, woven fabric of cellulose, polypropylene, polyester, nylon,
Alternatively, it is preferably formed of a porous film.
Further, the semisolid drug adhesion inhibiting substance is preferably a water repellent substance, for example, silicone.

Further, to achieve the above object, an application device main body having a through-hole, a semi-solid drug application member provided to cover the through-hole on one surface of the application device main body,
A protective sheet that covers the application member, further has a semi-solid drug adhesion inhibitor applied to a surface portion at a position corresponding to the application member, and is detachably fixed to the application device body; A breakable thin film provided on the other surface of the applicator body so as to cover the other opening, a semi-solid drug attached to the surface of the thin film, and the semi-solid drug so as to cover the semi-solid drug. And a semi-solid drug-coated film fixed to the applicator body.

The member for applying a semisolid drug preferably has a pore communicating with a through hole of the applicator main body.

Therefore, the semisolid drug application device of the present invention will be specifically described with reference to embodiments shown in the drawings.

The semi-solid drug application device 1 of the present invention comprises an application device body 2
A semi-solid medicine applying member 4 provided on the applicator main body 2, a semi-solid medicine 5 attached to the applying member surface, and a protective sheet 3 covering the semi-solid medicine 5. The semi-solid drug adhesion inhibiting substance 6 is applied to the surface portion where the semi-solid drug 5 comes into contact, and is fixed to the applicator main body 2 in a releasable manner.

Therefore, the semisolid drug application device of the present invention will be described with reference to the embodiment shown in FIGS.

FIG. 1 is a cross-sectional view of a semi-solid drug application device according to one embodiment of the present invention, and FIG. 2 is a plan view of the semi-solid drug application device of FIG.

The semisolid drug application device 1 of this embodiment includes an application device main body 2 and a protective sheet 3 whose peripheral edge is fused to the lower surface of the application device main body 2 so as to be peelable.

Specifically, as shown in FIG. 1 and FIG. 2 and FIG. 3 and FIG.
A member 4 for applying a semi-solid medicine fixed to one surface of the main body 2 of the applicator, a semi-solid medicine 5 attached to the surface of the member 4 for application, and a semi-solid medicine adhering surface of the main body 2 of the applicator. And a protective sheet 3 for protection. And protective sheet 3
As shown in FIGS. 1 and 3, a semi-solid drug-adhesion-suppressing substance application section 6 partially applied to the inner surface is provided. At the same time, the surface of the semi-solid drug 5 is covered. Then, as shown in FIG. 2 and FIG.
The protective sheet 3 is fixed by an endless fixing portion 10 provided so as to surround the semi-solid medicine applying member 4. The protective sheet 3 can be peeled off from the applicator main body 2.

As shown in FIG. 1, the applicator main body 2 is provided with a medicine applying member 4 near the left end. The applicator main body 2 is formed of a resin sheet having moderate flexibility. For example, a resin sheet having a thickness of 0.1 to 3 mm and having no dissolution even when it comes into contact with a chemical such as polypropylene, polyethylene, or polyester is preferable. Used for Also,
The applicator main body 2 may be provided with a gas barrier film layer on its upper surface. Further, the applicator body 2 may be provided with an adhesive resin layer on the lower surface. By providing the gas barrier film layer, it is possible to prevent the permeation of moisture in the semi-solid drug filled therein or the denaturation of the semi-solid drug due to the permeation of oxygen from the outside. As the gas barrier film layer, a metal foil such as aluminum, silver, and gold, or a metal vapor-deposited film having aluminum, silver, and gold deposited on the surface, a gas barrier resin film, for example, polyvinylidene chloride, polyvinylidene chloride -Films such as polyvinyl chloride and high density polyethylene can be suitably used. Further, the adhesive resin layer is formed of the protective sheet 3
And for bonding with the coating member 4.
What is necessary is just to be provided in the site | part which should adhere | attach the member 4 for application | coating with at least the peripheral edge of the application tool main body 2. As the adhesive resin layer, a polyolefin such as polyethylene and polypropylene, and a heat-meltable resin such as an ethylene-vinyl acetate copolymer are preferably used. Further, a surface protective layer may be provided as the uppermost layer of the applicator main body 2. The surface protective layer may be formed by coating a synthetic resin, for example, polyester, polypropylene, polyethylene, nylon, PET, epoxy resin, polyamide resin, or laminating the above synthetic resin film, paper, or the like. preferable. This surface protective layer can also be used as a printing layer for describing necessary items such as the name of the substance to be filled and the filling amount.

In the vicinity of the left end of the applicator main body 2, a semisolid medicine applying member 4 is fixed. As shown in FIG. 2 and FIG. 4, the semi-solid drug application member 4 has a length and width of the coating device main body 2.
Less than. Further, in a state where the semi-solid drug applying member 4 is fixed to the applicator main body 2, the semi-solid drug applying member 4 is covered between the peripheral edge of the semi-solid drug applying member 4 and the peripheral edge of the applicator main body 2. The surface portion of the coating device main body 2 which is not formed is formed. The application member is used for applying a drug to a wound, and is preferably formed of a material having a soft feel. As the size of the coating member, the area of the lower surface of the coating device main body 2 is
About 1/50 to 1/4 is preferable, specifically, 2 × 2 mm to 30 ×
About 30 mm is preferable. Furthermore, it is preferable that the adhesive can be fixed to the above-described applicator body 2 without using an adhesive.

For example, when the fixing surface of the applicator main body 2 to the coating member 4 does not have heat fusion property, the coating member 4 itself having heat fusion property is used. Specifically, Non-woven fabrics, woven fabrics and porous membranes such as polyester, polypropylene and polyethylene are preferred. When at least a portion of the applicator main body 2 to which the coating member 4 is fixed has a heat-fusing property, the fixing surface is melted to penetrate between the fibers to be bonded. For example, a nonwoven fabric such as cellulose, a woven fabric, and a porous membrane are suitable. When the applicator main body 2 has a heat-sealing property, the applicator main body 2 and the applying member 4 are co-extruded to fix the applying member 4, or the applicator main body 2 and the applying member 4 In a state in which the components are stacked, a heated needle or the like may be passed through both members to fix the application member 4 to the application device main body 2.

Then, a semi-solid drug is attached to the surface of the coating member 4. As the semi-solid drug, a semi-solid drug such as an ointment, cream, gel, viscous lotion and the like is used. Further, the amount of the semi-solid drug attached to the coating member 4 is preferably about 0.01 to 5 g.

The protective sheet 3 is fixed to the lower surface of the application tool main body so as to be peelable. As the protection sheet 3,
It is preferable to have a gas barrier film layer and an adhesive resin layer provided on this layer. The gas barrier film layer is for preventing the permeation of moisture in the semi-solid drug filled therein or the denaturation of the semi-solid drug due to the permeation of oxygen from the outside. As the gas barrier film layer, a metal foil such as aluminum, silver, and gold or a metal vapor-deposited film having aluminum, silver, and gold deposited on the surface, a gas barrier resin film, for example, polyvinylidene chloride, polyvinylidene chloride -Films such as polyvinyl chloride and high density polyethylene can be suitably used. Further, the adhesive resin layer is for fusing the peripheral edge of the protective sheet 3 to the peripheral edge of the applicator body 2,
The protective sheet 3 only needs to be provided at least on the peripheral edge of the surface that comes into contact with the applicator body 2. As the adhesive resin layer, a polyolefin such as polyethylene and polypropylene, and a heat-meltable resin such as an ethylene-vinyl acetate copolymer are preferably used. Furthermore, if the fusing surface of the applicator main body 2 is formed of a low melting point resin, the adhesive resin layer may have a certain degree of heat melting property and may have a low melting point, such as polyester or polypropylene. , Polyethylene, nylon, PET, epoxy resin, polyamide resin and the like. Further, if the gas barrier film layer can be directly fused to the applicator main body 2, the adhesive resin layer may be omitted.

Then, a semi-solid drug adhesion inhibiting substance is applied to the inner surface of the protective sheet 3 at the portion that comes into contact with the semi-solid drug. Specifically, as shown in FIGS. 1 and 3, the protective sheet 3 includes a semi-solid drug-adhesion-suppressing substance application section 6 partially applied to the inner surface thereof. 6 is in contact with the semi-solid drug 5 and covers the surface of the semi-solid drug 5.

This adhesion-suppressing substance is used to prevent the drug from adhering to the protective sheet when the protective sheet is peeled from the applicator main body, and includes organopolysiloxane, methylphenylpolysiloxane, dimethylpolysiloxane, and methylpolysiloxane. Silicone such as cyclosiloxane, acrylallylpolysiloxane, silicone polyether copolymer, trimethylsiloxysilicic acid, amino-modified siloxane, silicone emulsion, trifluoropropylmethylpolysiloxane, or liquid paraffin if the semi-solid drug is a hydrophilic base When the semisolid drug is a lipophilic base, polyethylene glycol or the like can be used.

As shown in FIGS. 2 and 4, the applicator main body 2 and the protective sheet 3 are fixed by an endless fixing portion 10 provided so as to surround the semi-solid drug applying member 4. Specifically, a surface portion of the coating device main body 2 that is not covered by the semi-solid drug coating member 4 is provided between a peripheral edge of the semi-solid drug coating member 4 and a peripheral edge of the coating device main body 2. The part 2 and the protection sheet 3 are made of a semi-solid drug application member 4.
Is fixed by a fixing portion 10 formed on the surface portion of the applicator main body 2 which is not covered by the semi-solid medicine applying member 4 so as to surround the device. As shown in FIGS. 1 and 2, a peeling start portion 7 for peeling off the protective sheet 3 is formed at an end of the protective sheet 3.

Then, the semi-solid drug application device 1 of the present invention forms the application device main body 2 and the protection sheet 3 in which the semi-solid drug is adhered to the surface of the application member as described above, and then forms the peripheral edge of the application device main body 2 and the protection. It is created by fusing the periphery of the sheet 3 with heat, ultrasonic waves, high frequency or the like.

Next, the semisolid drug application device of the embodiment shown in FIGS. 3 and 4 will be described.

In the semi-solid drug application device 1 of this embodiment, the basic configurations of the application device main body 2 and the protective sheet 3 are the same as those shown in FIGS. 1 and 2. The different points are the position where the semi-solid medicine applying member is attached and the shape of the applicator main body 2 corresponding to that position. Coating device body 2
3, has a concave portion 12 at the center thereof, and the coating member 4 is fixed to the inner surface of the concave portion 12. As shown in FIG. Further, the surface of the coating member 4 is provided with a semi-solid drug 5.
Is adhered to the surface of the protective sheet 3 in a portion that comes into contact with the semisolid medicine, and a medicine adhesion suppressing substance is applied. Further, the concave portion of the application tool main body 2 is
After the protective sheet 3 is peeled off, the recess 12 is pressed from the outside so that it can project.
The semi-solid drug 5 can be easily applied to the wound site by curving around the center.

Next, the coating container 1 of the embodiment shown in FIGS. 5 and 6 will be described.

The coating container 1 has a through hole 14 communicating the upper surface and the lower surface.
And a semi-solid drug application member 4 provided on the lower surface of the application device body 2 so as to cover the through hole 14, and covers the application member 4, and further corresponds to the application member 4. The semi-solid drug adhesion inhibiting substance 6 is applied to the surface portion at the position to be applied, and is provided on the upper surface of the applicator main body 2 at a position corresponding to the applying member 4 and the protective sheet 3 removably fixed to the applicator main body. Rupturable thin film 18 and thin film 18
And a semi-solid drug-coated film 16 fixed to the applicator body so as to cover the semi-solid drug 5.

The applicator main body 2 has a plurality of through-holes 14 near the left end as shown in FIG.
A member 4 for applying a medicine is provided so as to cover.
The applicator main body 2 is formed of a resin sheet having an appropriate flexibility. For example, a resin sheet having a thickness of 0.1 to 3 mm, which does not elute when contacted with a chemical such as polypropylene, polyethylene, or polyester is preferable. Used for As the through hole 14, a hole having a diameter of about 0.05 to 2 mm
It is preferable to provide about zero. In addition, the coating device main body 2
May have a gas barrier film layer on its upper surface. Further, the applicator body 2 may be provided with an adhesive resin layer on the lower surface. Further, a surface protective layer may be provided as the uppermost layer of the applicator main body 2. This surface protective layer can also be used as a printing layer for describing necessary items such as the name of the substance to be filled and the filling amount.

The semisolid drug application member 4 provided near the left end of the applicator main body 2 is used for applying a drug to a wound, and is preferably formed of a material having a soft touch. . Further, it is preferable that the material can be fixed to the above-mentioned applicator body without using an adhesive. For example, a material having heat-fusibility is preferable.

For example, when the fixing surface of the applicator main body 2 to the coating member 4 does not have heat fusion property, the coating member 4 itself having heat fusion property is used. Specifically, Non-woven fabrics, woven fabrics and porous membranes such as polyester, polypropylene and polyethylene are preferred. When at least a portion of the applicator main body 2 to which the coating member 4 is fixed has heat-fusing properties, the fixing surface is melted to penetrate between the fibers to be bonded. For example, a nonwoven fabric such as cellulose, a woven fabric, and a porous membrane are suitable. When the applicator main body 2 has a heat-sealing property, the applicator main body 2 and the applying member 4 are co-extruded to fix the applying member 4, or the applicator main body 2 and the applying member 4 In a state in which the components are stacked, a heated needle or the like may be passed through both members to fix the application member 4 to the application device main body 2.
If the coating member 4 is a member (for example, a nonwoven fabric, a woven fabric, a porous membrane, or the like) through which the semi-solid drug easily penetrates and has a high porosity, no pores are provided. You may.

On the upper surface of the applicator main body 2, a rupturable thin film 18 is provided so as to cover the through-hole 14, and a semi-solid drug is attached on the thin film 18. As the semi-solid drug, a semi-solid drug such as an ointment, cream, gel, viscous lotion and the like is used. The whole of the semi-solid medicine 18 is covered with a semi-solid medicine covering film 16, and the periphery of the covering film 16 is fixed to the applicator main body. In this embodiment, the semi-solid drug is pressed by pressing the semi-solid drug coated film 16 from the outside, and the force causes the breakable thin film 18 to break, and the through hole 14
And is moved to the surface of the semi-solid drug application member 4 through the With such a configuration, the coating member 4 and the semi-solid drug 6 can be prevented from coming into contact with each other until use, and the drug can be prevented from being absorbed by the coating member. Can be maintained.

The rupturable thin film 18 needs to be rupturable when the semisolid drug is pressed as described above, and does not affect the semisolid drug (for example, dissolution, Is not eluted). As the thin film 18 satisfying such conditions, a metal thin film (for example, aluminum foil), a non-stretched or low-stretched polyolefin film (for example, non-stretched or low-stretched polyethylene or polypropylene film), or a semi-solid drug is a lipophilic base. In the case of, a water-soluble polymer film such as polyvinyl alcohol, hydroxymethylcellulose, sodium carboxymethylcellulose, pullulan, and oblate, and in the case of a hydrophilic base, dissolved in an organic solvent such as ethylcellulose, polyvinylbutyral, alkyd resin, and acrylic resin. Alternatively, a film formed of a resin supplied as an emulsion can be used.

Further, the semi-solid drug-coated film 16 preferably has a gas barrier film layer and an adhesive resin layer provided on this layer. The gas barrier film layer is for preventing the permeation of moisture in the semisolid drug filled therein or the metamorphosis of the semisolid drug due to the permeation of oxygen from the outside. As the gas barrier film layer, a metal foil such as aluminum, silver, and gold or a metal vapor-deposited film having aluminum, silver, and gold deposited on the surface, a gas barrier resin film, for example, polyvinylidene chloride, polyvinylidene chloride -Films such as polyvinyl chloride and high density polyethylene can be suitably used. Further, the adhesive resin layer is for fusing the peripheral edge of the coating film 16 to the coating device main body 2 and may be provided at least on the peripheral edge of the coating film 16. As the adhesive resin layer, a polyolefin such as polyethylene and polypropylene, and a heat-meltable resin such as an ethylene-vinyl acetate copolymer are preferably used. Furthermore, as long as the fusion surface of the above-mentioned applicator body 2 is formed of a low melting point resin, the adhesive resin layer only needs to have a certain degree of heat melting property, and does not have to have a low melting point. It may be formed of polyester, polypropylene, polyethylene, nylon, epoxy resin, polyamide resin, or the like. Also,
This adhesive resin layer may be omitted as long as the gas barrier film layer can be directly fused to the applicator body 2.

The protective sheet 3 is fixed to the lower surface of the application tool main body so as to be peelable. As the protection sheet 3,
Polyolefins such as polyethylene and polypropylene,
If the heat-fusible resin such as an ethylene-vinyl acetate copolymer, and further, the fusion surface of the above-described applicator body 2 is formed of a low-melting-point resin, this adhesive resin layer has a certain degree of heat-fusibility. As long as it has no low melting point,
It may be formed of polyester, polypropylene, polyethylene, nylon, PET, epoxy resin, polyamide resin, or the like.

Then, a semi-solid drug adhesion inhibiting substance is applied to the inner surface of the protective sheet 3 at a position corresponding to the semi-solid drug application member 4 (a portion in contact with the application member 4). The adhesion-suppressing substance is used to prevent the semi-solid drug that has moved to the surface of the coating member 4 from adhering to the protective sheet by pressing the semi-solid drug-coated film 16. Silicone such as siloxane, methylphenylpolysiloxane, dimethylpolysiloxane, methylpolycyclosiloxane, acrylallylpolysiloxane, silicone polyether copolymer, trimethylsiloxysilicic acid, amino-modified siloxane, silicone emulsion, trifluoropropylmethylpolysiloxane, Liquid paraffin can be used when the solid drug is a hydrophilic base, and polyethylene glycol or the like can be used when the semi-solid drug is a lipophilic base. Further, at the end of the protective sheet 3, as shown in FIGS. 5 and 6, a peeling start portion 7 for peeling the protective sheet 3 is formed.

Then, after preparing the coating device main body 2 and the protection sheet 3 to which the rupturable thin film 18 and the coating member are fixed as described above, the medicine coating device of the present invention is used. And the peripheral edge of the semi-solid drug-coated film 16 is attached to the breakable thin film 18 by heat, ultrasonic waves, high frequency, etc. It is formed by fusing with high frequency or the like.

[Operation] The operation of the semisolid drug application container of the present invention will be described with reference to the embodiment shown in FIG. 1 and FIG.

First, necessary disinfection work is performed on the body part to which the semi-solid drug is applied. Then, the finger is put on the peeling start portion 7 provided at the right end of the protective sheet 3 of the coating container 1 of the present invention, and the protective sheet 3 is peeled from the coating tool main body 2 by pulling. By this peeling, the lower surface of the coating member 4 and the coating device main body 2 to which the semi-solid drug 5 is attached are exposed. Since the lower surface of the applicator main body 2 was originally covered with the upper film, it was a clean surface free from adhesion and propagation of bacteria and the like. Then, the semi-solid drug 5 is applied to the affected area using the application member 4 without contaminating the surface of the application device main body 2, particularly the application member 4 and the vicinity thereof with the finger.

[Example] (Example 1) A polyethylene sheet (1 m thick) was used as the applicator body.
m, width 20mm, length 70mm) near the end of a cellulosic non-woven fabric (10 × 10mm, trade name Bemliese, manufactured by Asahi Kasei Corporation)
(Thickness 12μm), aluminum (12μm, gas barrier film layer), unstretched polypropylene (thickness 50μm,
Adhesive resin layer) three-layer structure (width 20mm, length 700m)
m), an organopolysiloxane (SH200 oil, manufactured by Toray Silicon Co., Ltd.) was partially coated near the end (on the unstretched polypropylene layer) and treated at 100 ° C. for 4 hours. Then, after 0.5 g of the semi-solid drug was put on the cellulosic nonwoven fabric, the periphery of the applicator body and the protective sheet were heat-sealed as shown in FIG. In addition, the following were used as the semisolid drug.

Cetrimide 0.5 g Lidocaine 2.0 g Japanese Pharmacopoeia white ointment 90 g Liquid paraffin qs 100 g For semi-solid drugs, add 5 g of liquid paraffin with cetrimide and lidocaine, grind and heat to 80 ° C to dissolve white ointment 90 g was added, and the remaining liquid paraffin was added, followed by cooling with stirring.

The product can be used as an ointment for wounds such as cuts, abrasions, and cuts.

(Example 2) As an applicator body, a polypropylene / ethylene copolymer sheet (thickness 1 mm, width 25 mm, length 100 mm) having a concave portion in the center as shown in FIG. Using. As the member for applying the semisolid drug, a polypropylene nonwoven fabric (0.8 mm in thickness, 10 × 20 mm) to which polyethylene was adhered by an extrusion lamination method was used, and the polyethylene surface was fused to the application device body by ultrasonic waves.
The same protective sheet as that used in Example 1 was used, and the semi-solid drug used had the following formulation.
0g was put.

Silver sulfadiazine 1g White petrolatum 8g Stearyl alcohol 3g Isopropyl myristate 5g Span 80 2g Polyoxyl stearate 4 4g Propylene glycol 10g Methyl parapen 0.1g Purified water qs 100g Sum up. Heat white petrolatum, stearyl alcohol, isopropyl myristate, span 80, polyoxyl stearate 40 to 80 ° C and mix. Separately after heating purified water to 75 ° C., put it in a container containing white petrolatum, stearyl alcohol, isopropyl myristate, span 80, polyoxyl stearate 40, and further add propylene glycol, silver sulfadiazine, and methyl parapen, After emulsifying with vigorous stirring, the mixture was cooled while gradually stirring.

And, when using this semi-solid drug container, it was used for a 1cm x 4cm superficial 2 degree burn injured by ironing,
The semi-solid drug was easily applied and healed without causing infection.

[Effects of the Invention] A semisolid drug application device for application according to the present invention includes an application device body, a semisolid drug application member fixed to one surface of the application device body, and a semisolid drug application member attached to the application member surface. A semi-solid drug, and a protective sheet for protecting the semi-solid drug-adhering surface of the applicator body, the protective sheet includes a semi-solid drug adhesion-suppressing substance application portion partially applied to the inner surface, The semi-solid drug adhesion inhibiting substance application section contacts the semi-solid drug and covers the surface of the semi-solid drug, and further, the applicator body and the protection sheet surround the semi-solid drug application member. The protective sheet is fixed by the endless fixing portion provided as described above, and the protective sheet is peelable from the applicator main body.

For this reason, since the surface of the applicator main body at the portion covered by the protective sheet after the protective sheet has been peeled off is a clean surface free of adhesion and propagation of bacteria, etc., application of the semi-solid drug to the affected area is performed. In this case, even if it comes into contact with the wound site, it is safe and the semi-solid drug can be applied hygienically. Moreover, in the semisolid drug application device of the present invention, the application operation is easier because the amount of the semisolid drug required for one application is previously attached to the surface of the application member. In addition, since the semi-solid drug adhesion inhibitor applied portion of the protective sheet is in contact with the semi-solid drug, when the protective sheet is peeled, the semi-solid drug attached to the protective sheet side is small,
The semi-solid drug attached to the surface of the coating member can be used effectively.

Further, the semi-solid drug application container of the present invention is a coating device main body having a through-hole, a semi-solid drug coating member provided to cover the through-hole on one surface of the coating device main body, A protective sheet that covers the application member, further has a semi-solid drug adhesion inhibiting substance applied to a surface portion at a position corresponding to the application member, and is releasably fixed to the application device body; So as to cover the other opening of
A rupturable thin film provided on the other surface of the coating device main body, a semi-solid drug attached to the surface of the thin film, and a semi-solid fixed to the coating device main body so as to cover the semi-solid drug. Since it is composed of a drug-coated film, the surface of the applicator body after the protective sheet has been peeled off is covered with the protective sheet, so it is a clean surface free from adhesion and propagation of bacteria, etc. Even when the medicine is applied to the affected area, even if it comes into contact with the wound site, it is safe and the semisolid medicine can be applied hygienically. Further, the semi-solid drug application device of the present invention is suitable for filling the amount of semi-solid drug required for one application. Furthermore, since the medicine does not come into contact with the medicine application member during storage, the medicine can be used effectively without being absorbed by the application member, and the medicine is maintained in a stable state until use. be able to.

[Brief description of the drawings]

FIG. 1 is an enlarged sectional view of a semi-solid medicine applicator according to one embodiment of the present invention, FIG. 2 is an enlarged sectional view of the semi-solid medicine applicator of FIG. 1, and FIG. 3 is another embodiment. , FIG. 4 is a plan view of the semi-solid drug application device of FIG. 3, FIG. 5 is an enlarged cross-sectional view of a semi-solid drug application device of another embodiment, FIG. FIG. 6 is a plan view of the semisolid drug application device of FIG. DESCRIPTION OF SYMBOLS 1 ... Semi-solid medicine applicator 2 ... Applicator main body 3 ... Protective sheet 4 ... Semi-solid medicine application member 5 ... Semi-solid medicine 6 ... Semi-solid medicine vicinity suppressing member 7 ... Peeling start part 10 ... Heat-fusion part

──────────────────────────────────────────────────続 き Continued on the front page (58) Field surveyed (Int.Cl. ⁶ , DB name) A61M 35/00

Claims (10)

(57) [Claims] 1. A coating device main body, a semi-solid drug application member fixed to one surface of the coating device main body, a semi-solid drug attached to the coating member surface, and a half of the coating device main body. A protective sheet for protecting the solid drug-adhering surface, wherein the protective sheet comprises a semi-solid drug-adhesion-suppressing substance-applied portion partially applied to the inner surface, and the semi-solid drug-adhesion-suppressing-material-applying section includes The semi-solid medicine is in contact with the medicine and covers the surface of the semi-solid medicine, and the applicator body and the protective sheet are fixed by an endless fixing part provided so as to surround the semi-solid medicine application member. Wherein the protective sheet is peelable from the applicator main body. 2. The semisolid drug application device according to claim 1, wherein the protective sheet has an adhesive resin layer and a gas barrier film layer provided below the adhesive resin layer. 3. The semisolid drug application device according to claim 1, wherein the protective sheet has a peeling start portion for peeling the protective sheet. 4. The semisolid drug application device according to claim 1, wherein the semisolid drug application member is formed of a material having a soft feel with little absorption of the semisolid drug. 5. The applicator body has a recess,
The semisolid drug application device according to any one of claims 1 to 4, wherein the member for applying a semisolid drug is attached to the recess. 6. The semi-solid drug according to claim 1, wherein the semi-solid drug application member is formed of a nonwoven fabric, woven fabric, or a porous film of cellulose, polypropylene, polyester, or nylon. Application equipment. 7. The semi-solid drug application device according to claim 1, wherein the semi-solid drug adhesion inhibiting substance is a water repellent substance. 8. The semisolid drug application device according to claim 7, wherein said water repellent substance is silicone. 9. A coating device main body having a through-hole, a semi-solid drug application member provided on one surface of the coating device main body so as to cover the through-hole, and covering the coating member. A semi-solid drug adhesion-suppressing substance is applied to a surface portion at a position corresponding to the application member, and the protective sheet is detachably fixed to the application device main body, and covers the other opening of the through hole. A rupturable thin film provided on the other surface of the applicator main body, a semi-solid drug attached to the surface of the thin film, and a semi-solid fixed to the applicator main body so as to cover the semi-solid drug. A semisolid drug application device comprising a solid drug coated film. 10. The semi-solid drug application member has a pore communicating with a through-hole of the applicator main body.
5. The semi-solid drug application device according to 4.