JP2870863B2 - Liquid gas exchange module - Google Patents
Liquid gas exchange moduleInfo
- Publication number
- JP2870863B2 JP2870863B2 JP1254862A JP25486289A JP2870863B2 JP 2870863 B2 JP2870863 B2 JP 2870863B2 JP 1254862 A JP1254862 A JP 1254862A JP 25486289 A JP25486289 A JP 25486289A JP 2870863 B2 JP2870863 B2 JP 2870863B2
- Authority
- JP
- Japan
- Prior art keywords
- liquid
- exchange module
- gas
- gas exchange
- hollow fiber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Description
【発明の詳細な説明】 〔産業上の利用分野〕 本発明は、液中ガス交換モジュールに関する。更に詳
しくは、ポンピング機能を有する液中ガス交換モジュー
ルに関する。Description: TECHNICAL FIELD The present invention relates to a submerged gas exchange module. More specifically, the present invention relates to a submerged gas exchange module having a pumping function.
〔従来の技術〕および〔発明が解決しようとする課題〕 中空糸膜群の端部をポッティングして収容した筒状体
よりなる従来周知のモジュールは、交換能、分離機能な
どを有してはいるものの、処理さるべき液体の輸送には
別のポンプを必要としている。[Prior art] and [Problems to be solved by the invention] A conventionally well-known module consisting of a tubular body in which the ends of hollow fiber membrane groups are potted and housed has no exchangeability, separation function, etc. However, transporting the liquid to be treated requires a separate pump.
このため、組成などの異なる被処理液体を連続的に処
理する場合には、モジュール、輸送チューブの交換だけ
にとどまらず、ポンピング装置の洗浄あるいは交換など
も必要としている。また、医療用の入口肺の場合、現状
では交換装置とポンプ装置とが別になっており、体外か
らバイパスする場合経路が長くなり、複雑になっている
が、交換部とポンプ部とが一体化されれば装置自体が簡
略化され、バイパスが短くなり、チューブによる圧力損
失および外的影響を軽減することも可能となる。Therefore, in the case of continuously processing liquids having different compositions and the like, not only replacement of modules and transport tubes, but also cleaning or replacement of a pumping device is required. In addition, in the case of a medical entrance lung, the exchange device and the pump device are currently separate, and when bypassing from outside the body, the path is long and complicated, but the exchange unit and the pump unit are integrated. This simplifies the device itself, shortens the bypass, and reduces pressure loss and external effects due to the tubing.
本発明の目的は、液中ガス交換モジュールにおいて、
ポンピング機能を有するものを提供することにある。An object of the present invention is to provide a submerged gas exchange module,
An object is to provide one having a pumping function.
かかる目的を達成させる本発明の液中ガス交換モジュ
ールは、ゴム状弾性を有する中空糸膜群の端部をポッテ
ィングして収容した筒状体の両端部に、それぞれ弁ボー
ルを備えた被処理液体吸入口および処理済液体排出口を
設け、筒状体胴部にはポンピング装置に接続される気体
導入口および気体排出口を設けてなる。The gas exchange module in liquid according to the present invention, which achieves the above object, comprises a liquid to be treated, which is provided with a valve ball at each end of a tubular body containing the ends of a hollow fiber membrane group having rubber-like elasticity. An inlet and a treated liquid outlet are provided, and a gas inlet and a gas outlet connected to a pumping device are provided in the cylindrical body.
図面の第１図は、本発明に係る液中ガス交換モジュー
ルの一態様を示す概要図である。筒状体１内には、好ま
しくは膜厚が約2.5mm以下でかつ外径（mm）×0.3以下の
シリコーンゴム中空糸膜などのゴム状弾性を有する中空
糸膜2,2′，・・・・が多数本の群として、その端部を
ポッティング３して収容されている。そして、その両端
部4,4′には、被処理液体吸入口５および処理済液体排
出口６が設けられており、ポンピング装置７の作動によ
る減圧時には、ゴム状弾性を有する中空糸膜の径が膨ら
み、弁ボール8,8′は図示された如く内側に向けて吸い
寄せられるが、液体吸入口側の弁ボール８は網９によっ
てそれ以上の移動が抑止されるため被処理液体の吸入口
５からの吸入を可能とし、またポンピング装置７の作動
による加圧時には、逆にゴム状弾性を有する中空糸膜の
径が縮まり、弁ボール8,8′は外側に向けて押しやられ
るが、液体排出口側の弁ボール８′は網９′によってそ
れ以上の移動が抑止されるため処理済液体の排出口６か
らの排出を可能とする。FIG. 1 is a schematic diagram showing one embodiment of a submerged gas exchange module according to the present invention. A hollow fiber membrane 2,2 'having a rubber-like elasticity such as a silicone rubber hollow fiber membrane having a thickness of preferably about 2.5 mm or less and an outer diameter (mm) .times.0.3 or less is provided in the tubular body 1. Are housed as a group of a large number of pottings with potting 3 at their ends. At both ends 4, 4 ', a liquid to be treated inlet 5 and a treated liquid outlet 6 are provided, and when the pumping device 7 is depressurized, the diameter of the hollow fiber membrane having rubber elasticity is reduced. Bulges and the valve balls 8, 8 'are drawn inward as shown, but the valve ball 8 on the liquid suction port side is restrained from further movement by the net 9, so that the liquid suction port 5 When the pumping device 7 is pressurized, the diameter of the hollow fiber membrane having rubber elasticity is reduced, and the valve balls 8, 8 'are pushed outward, but the liquid is discharged. Further movement of the valve ball 8 'on the outlet side is suppressed by the net 9', so that the treated liquid can be discharged from the discharge port 6.
筒状体１の胴部には、液体吸入口側に気体導入口10
が、また液体排出口側に気体排出口11がそれぞれ設けら
れており、これらはポンピング装置７と接続される。ポ
ンピング装置は、筒状体内に供給する気体の圧力を変化
させ、前述の如く減圧−加圧をくり返すことにより、ゴ
ム状弾性を有する中空糸膜群に脈動を起こすことができ
る。A gas inlet 10 is provided on the body of the tubular body 1 at the liquid inlet side.
However, gas outlets 11 are provided on the liquid outlet side, respectively, and these are connected to the pumping device 7. The pumping device can pulsate the hollow fiber membrane group having rubber-like elasticity by changing the pressure of the gas supplied into the cylindrical body and repeating the depressurization and pressurization as described above.
この液中ガス交換モジュールを、例えば人工心肺とし
て用いる場合には、人工心臓用のポンピング装置から酸
素を筒状体内に供給し、その際減圧時には大気圧−100m
mHgの圧力を、また加圧時には大気圧＋400mmHgの圧力を
それぞれかけ、これに連動してゴム状弾性を有する中空
糸膜内の体積が変化し、弁ボールの作用と相まって、中
空糸膜によって隔てられた外部もしくは内部の気体が、
吸入された被処理液体中の気体と交換した状態で排出さ
れる。When this submerged gas exchange module is used, for example, as a heart-lung machine, oxygen is supplied from a pumping device for an artificial heart into the cylindrical body.
A pressure of mHg and a pressure of atmospheric pressure + 400 mmHg at the time of pressurization are applied, respectively, and the volume in the hollow fiber membrane having rubber elasticity changes in conjunction with this, and in conjunction with the action of the valve ball, it is separated by the hollow fiber membrane. External or internal gas
It is discharged in a state where it is exchanged for the gas in the liquid to be processed which has been sucked in.
液中ガス交換の例としては、人工肺機能、人工心臓機
能を付与する血液中に二酸化炭素と空気中の酸素との交
換（膜材：シリコーンゴム）の他、酸素富化・二酸化炭
素交換（膜材:PTFE−シリコーンゴムブレンド体、PE−
シリコーンゴムブレンド体、PP−シリコーンゴムブレン
ド体、フルオロカーボン含浸シリコーンゴムなど）、水
素・窒素分離（膜材:NBR,クロロプレンゴムなど）、水
・有機蒸気分離（膜材：シリコーンゴム,PTFE−シリコ
ーンゴムブレンド体、PE−シリコーンゴムブレンド体、
PP−シリコーンゴムブレンド体、NBR、アクリルゴムな
ど）が挙げられる。ガス交換は、濃度勾配による拡散で
行われ、例えば被処理液体中に二酸化炭素が多く、これ
を酸素と交換する場合には、供給する気体としては二酸
化炭素を含まず、酸素濃度の高い気体、好ましくは純酸
素ガスが用いられる。Examples of gas exchange in liquid include exchange of carbon dioxide in blood and oxygen in air that provide an artificial lung function and an artificial heart function (membrane material: silicone rubber), as well as oxygen enrichment and carbon dioxide exchange ( Membrane material: PTFE-silicone rubber blend, PE-
Silicone rubber blend, PP-silicone rubber blend, fluorocarbon-impregnated silicone rubber, etc., hydrogen / nitrogen separation (membrane material: NBR, chloroprene rubber, etc.), water / organic vapor separation (membrane material: silicone rubber, PTFE-silicone rubber) Blend, PE-silicone rubber blend,
PP-silicone rubber blend, NBR, acrylic rubber, etc.). Gas exchange is carried out by diffusion with a concentration gradient, for example, when the liquid to be treated contains a large amount of carbon dioxide and this is exchanged with oxygen, the gas to be supplied does not contain carbon dioxide and has a high oxygen concentration. Preferably, pure oxygen gas is used.
本発明により、ポンピング機能を有する液中ガス交換
モジュールが提供される。According to the present invention, a submerged gas exchange module having a pumping function is provided.
次に、実施例について本発明を説明する。 Next, the present invention will be described with reference to examples.
実施例 筒状体としてポリカーボネート製シリンダを、中空糸
膜群として1800本のシリコーンゴム製中空糸膜（内径0.
3mm、外径0.6mm、長さ200mm、膜有効面積0.19m2）を、
またポンピング装置として空気ポンプ（シナノ製作所製
人工呼吸器SN−480）をそれぞれ用い、図示された態様
の液中ガス交換モジュールを作製し、シュミレート実験
を行った。Example A polycarbonate cylinder was used as the cylindrical body, and 1800 silicone rubber hollow fiber membranes (with an inner diameter of 0.
3mm, outer diameter 0.6mm, length 200mm, effective membrane area 0.19m 2 )
In addition, an air pump (a respirator SN-480 manufactured by Shinano Seisakusho Co., Ltd.) was used as a pumping device, and a gas exchange module in liquid as shown in the figure was manufactured, and a simulation experiment was performed.
即ち、液体注入口および排出口から７％食塩水（生理
食塩水）を注入し、各中空糸膜内のエアを十分に脱気し
た後、空気ポンプ内から純酸素ガスを１分間50サイクル
で、圧力の脈動を差圧500mmHgで与えた。このときの被
処理液注入口の流量は41ml/分で、気体導入口と排出口
での酸素分圧差は297mmHgであった。That is, 7% saline (physiological saline) is injected from the liquid inlet and the outlet, and the air in each hollow fiber membrane is sufficiently evacuated. Then, pure oxygen gas is supplied from the air pump at 50 cycles for 1 minute. A pressure pulsation was applied at a differential pressure of 500 mmHg. At this time, the flow rate at the liquid inlet to be treated was 41 ml / min, and the oxygen partial pressure difference between the gas inlet and the gas outlet was 297 mmHg.
第１図は、本発明に係る液中ガス交換モジュールの一態
様を示す概要図である。 （符号の説明） １……筒状体 ２……中空糸膜 ５……液体吸入口 ６……液体排出口 ７……ポンピング装置 ８……弁ボール 10……気体導入口 11……気体排出口FIG. 1 is a schematic diagram showing one embodiment of a submerged gas exchange module according to the present invention. (Explanation of reference numerals) 1 ... cylindrical body 2 ... hollow fiber membrane 5 ... liquid suction port 6 ... liquid discharge port 7 ... pumping device 8 ... valve ball 10 ... gas inlet port 11 ... gas discharge Exit
───────────────────────────────────────────────────── フロントページの続き (58)調査した分野(Int.Cl.6，ＤＢ名) B01D 63/02 B01D 65/00 B01D 53/22 A61M 1/18 ──────────────────────────────────────────────────続 き Continued on the front page (58) Field surveyed (Int. Cl. 6 , DB name) B01D 63/02 B01D 65/00 B01D 53/22 A61M 1/18
Claims (1)
ッティングして収容した筒状体の両端部に、それぞれ弁
ボールを備えた被処理液体吸入口および処理済液体排出
口を設け、筒状体胴部にはポンピング装置に接続される
気体導入口および気体排出口を設けてなる液中ガス交換
モジュール。1. A liquid-to-be-processed suction port and a processed liquid discharge port each having a valve ball are provided at both ends of a cylindrical body in which the ends of a hollow fiber membrane group having rubber-like elasticity are potted and housed. A submerged gas exchange module comprising a cylindrical body provided with a gas inlet and a gas outlet connected to a pumping device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1254862A JP2870863B2 (en) | 1989-09-29 | 1989-09-29 | Liquid gas exchange module |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1254862A JP2870863B2 (en) | 1989-09-29 | 1989-09-29 | Liquid gas exchange module |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH03118822A JPH03118822A (en) | 1991-05-21 |
| JP2870863B2 true JP2870863B2 (en) | 1999-03-17 |
Family
ID=17270875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1254862A Expired - Fee Related JP2870863B2 (en) | 1989-09-29 | 1989-09-29 | Liquid gas exchange module |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2870863B2 (en) |
-
1989
- 1989-09-29 JP JP1254862A patent/JP2870863B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH03118822A (en) | 1991-05-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3727612A (en) | Dialysis method and apparatus | |
| US6267926B1 (en) | Device for removing entrained gases from liquids | |
| US3489647A (en) | Artificial organ for membrane dialysis of biological fluids | |
| US6241945B1 (en) | Modular combined pump, filtration, oxygenation and/or debubbler apparatus | |
| US7597677B2 (en) | Wearable ultrafiltration device | |
| CA1317843C (en) | Method and device for the extra-corporeal circulation of blood and for cardiovascular assistance | |
| US3463728A (en) | Dialysate capacity augmentation process | |
| US3505686A (en) | Device for effecting blood interchange functions | |
| EP0569318A1 (en) | Inflatable percutaneous oxygenator | |
| EP0853951A2 (en) | Inflatable percutaneous oxygenator with transverse hollow fibers | |
| US3212642A (en) | Artificial kidney | |
| JPS55114304A (en) | Dialyzing filter | |
| JPS62181061A (en) | Single assembly of heat exchanger and defoaming chamber | |
| WO1999049913A1 (en) | Compact blood oxygenator and perfusion circuit | |
| US20020153010A1 (en) | System and method for total liquid ventilation with very low priming volume | |
| US20090018484A1 (en) | System device and method for oxygenation | |
| US20110098624A1 (en) | Method and apparatus for treating renal disease with hemodialysis utilizing pulsatile pump | |
| US20210106745A1 (en) | Blood-degassing apparatus and blood-treatment system | |
| JP2870863B2 (en) | Liquid gas exchange module | |
| US3788474A (en) | Apparatus for concentrating a liquid containing non-ultrafiltrable elements | |
| GB2210797A (en) | Blood oxygenator apparatus | |
| WO2005028002A1 (en) | Blood oxygenation system with single lumen catheter | |
| DE19804536C2 (en) | Method for oxygenating blood | |
| JPH02156957A (en) | Hollow fiber film type oxygen enriching device | |
| JPS6084110A (en) | Composite type filtering concentrator |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |