JP2821050B2 - 核酸塩基識別法 - Google Patents

核酸塩基識別法

Info

Publication number
JP2821050B2
JP2821050B2 JP3286290A JP28629091A JP2821050B2 JP 2821050 B2 JP2821050 B2 JP 2821050B2 JP 3286290 A JP3286290 A JP 3286290A JP 28629091 A JP28629091 A JP 28629091A JP 2821050 B2 JP2821050 B2 JP 2821050B2
Authority
JP
Japan
Prior art keywords
fluorescence
nucleic acid
acid base
phosphorescence
state
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP3286290A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05126739A (ja
Inventor
満 石川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hamamatsu Photonics KK
Original Assignee
Hamamatsu Photonics KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hamamatsu Photonics KK filed Critical Hamamatsu Photonics KK
Priority to JP3286290A priority Critical patent/JP2821050B2/ja
Priority to DE69231400T priority patent/DE69231400T2/de
Priority to EP92310007A priority patent/EP0556509B1/en
Priority to US07/968,868 priority patent/US5322796A/en
Publication of JPH05126739A publication Critical patent/JPH05126739A/ja
Application granted granted Critical
Publication of JP2821050B2 publication Critical patent/JP2821050B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP3286290A 1991-10-31 1991-10-31 核酸塩基識別法 Expired - Fee Related JP2821050B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP3286290A JP2821050B2 (ja) 1991-10-31 1991-10-31 核酸塩基識別法
DE69231400T DE69231400T2 (de) 1991-10-31 1992-11-02 Verfahren zur Unterscheidung von Nukleinsäurebasentypen
EP92310007A EP0556509B1 (en) 1991-10-31 1992-11-02 Method for discriminating types of nucleic acid bases
US07/968,868 US5322796A (en) 1991-10-31 1992-11-02 Method of discriminating a kind of nucleic acids bases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3286290A JP2821050B2 (ja) 1991-10-31 1991-10-31 核酸塩基識別法

Publications (2)

Publication Number Publication Date
JPH05126739A JPH05126739A (ja) 1993-05-21
JP2821050B2 true JP2821050B2 (ja) 1998-11-05

Family

ID=17702469

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3286290A Expired - Fee Related JP2821050B2 (ja) 1991-10-31 1991-10-31 核酸塩基識別法

Country Status (4)

Country Link
US (1) US5322796A (enExample)
EP (1) EP0556509B1 (enExample)
JP (1) JP2821050B2 (enExample)
DE (1) DE69231400T2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2575270B2 (ja) * 1992-11-10 1997-01-22 浜松ホトニクス株式会社 核酸の塩基配列決定方法、単一分子検出方法、その装置及び試料の作成方法
EP0682671A4 (en) * 1993-02-01 1998-01-14 Seq Ltd METHOD AND DEVICES FOR SEQUENCING DNA.
US6766183B2 (en) 1995-11-22 2004-07-20 Medtronic Minimed, Inc. Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers
DE19634873A1 (de) * 1996-08-29 1998-03-12 Boehringer Mannheim Gmbh System zur Unterscheidung fluoreszierender Molekülgruppen durch zeitaufgelöste Fluoreszenzmessung
US6716394B2 (en) 1998-08-11 2004-04-06 Caliper Technologies Corp. DNA sequencing using multiple fluorescent labels being distinguishable by their decay times
WO2000009753A1 (en) * 1998-08-11 2000-02-24 Caliper Technologies Corp. Methods and systems for sequencing dna by distinguishing the decay times of fluorescent probes
US6528801B1 (en) * 1998-11-04 2003-03-04 The Research Foundation Of State University Of New York Method and apparatus for detecting radiation
US6515120B1 (en) 1999-05-25 2003-02-04 Praelux Incorporated Method for sequencing and characterizing polymeric biomolecules using aptamers and a method for producing aptamers
AU7105300A (en) 1999-09-03 2001-04-10 Lifebeam Technologies, Inc. Optical system for rapid polymer analysis
WO2002066986A2 (en) * 2001-02-15 2002-08-29 Medtronic Minimed, Inc. Polymers functionalized with fluorescent boronate motifs
US7045361B2 (en) 2001-09-12 2006-05-16 Medtronic Minimed, Inc. Analyte sensing via acridine-based boronate biosensors
EP1612541A1 (en) * 2003-04-04 2006-01-04 National Institute of Advanced Industrial Science and Technology Quantitative reagent, method and equipment of substance utilizing fluorescence lifetime

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959309A (en) * 1983-07-14 1990-09-25 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
US5171534A (en) * 1984-01-16 1992-12-15 California Institute Of Technology Automated DNA sequencing technique
US4962037A (en) * 1987-10-07 1990-10-09 United States Of America Method for rapid base sequencing in DNA and RNA
US4962045A (en) * 1988-05-02 1990-10-09 The Perkin-Elmer Corporation Time-resolved fluorimetric detection of lanthanide labeled nucleotides
US4962020A (en) * 1988-07-12 1990-10-09 President And Fellows Of Harvard College DNA sequencing

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ＢＩＯＣＨＥＭＩＣＡＬ ＡＮＤ ＢＩＯＰＨＹＳＩＣＡＬ ＲＥＳＥＡＲＣＨ ＣＯＭＭＵＮＩＣＡＴＩＯＮＳ Ｖｏｌ．１７０，Ｎｏ．１（１９９０）ｐ２７０−２８０
Ｊ．Ｐｈｏｔｏｃｈｅｍ．Ｐｈｏｔｏｂｉｏｌ．Ｂ．，Ｖｏｌ．５，Ｎｏ．３／４，（１９９０）ｐ３５９−３７７

Also Published As

Publication number Publication date
EP0556509B1 (en) 2000-08-30
EP0556509A3 (enExample) 1995-04-05
US5322796A (en) 1994-06-21
DE69231400D1 (de) 2000-10-05
DE69231400T2 (de) 2001-02-01
EP0556509A2 (en) 1993-08-25
JPH05126739A (ja) 1993-05-21

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