JP2813390B2 - Eyeglass lens for lensectomy - Google Patents

Description

Description: BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a spectacle lens, and more particularly, corrects blue vision caused in aphakic eye patients after cataract surgery and protects the eyes from light damage. The present invention relates to a spectacle lens for a cataract extractor, which is effective, and has an antiglare effect and fashionability.

[Related Art] Of incident sunlight that is normally poured into the eyes, ultraviolet rays are absorbed by the cornea, lens, and the like before reaching photosensitive cells, so that retinal tissues are protected from harmful ultraviolet rays. Ultraviolet absorption is performed exclusively in the cornea and lens, and the cornea absorbs wavelengths up to 300 nm. Although the lens varies depending on age, for example, a 50-year-old human lens absorbs light having a wavelength of up to about 400 nm. When the lens suffers from certain pathological changes, such as cataract, it is common practice to remove the lens by surgery and use spectacle lenses, intraocular lenses or contact lenses.

By the way, it is known that blue vision is likely to develop in aphakic eyes after cataract surgery. Blue vision is a symptom that occurs in the lens-excised eye and causes white objects to appear blue.Because the lens is originally a transparent body that is colored yellow or yellowish-brown, blue light is emitted when the lens is removed. As a result of reaching the retina without attenuation, the object appears bluer than in a normal eye.

As means for correcting this blue vision, for example, Japanese Patent Application Laid-Open
JP-A-204668 proposes a contact lens obtained by introducing a yellow or orange colorant into a transparent lens material.

[Problems to be Solved by the Invention] However, although the contact lens proposed in Japanese Patent Application Laid-Open No. Hei 1-204668 resembles the transmittance curve of the human lens, it is still insufficient, and the blue-eye correction is not sufficient. However, since the shape of the transmittance curve from 400 nm to 450 nm, which is important to the human eye, is different, the correction of blue vision is not completely performed. Further, since the contact lens contains only a yellow or orange colorant,
Due to the weak effect of dimming light above 450nm, it can hurt the eyes of people who are unavoidably occupationally exposed to strong sunlight. Further, the contact lens has a problem that it produces only a limited color tone and is poor in fashionability. Furthermore, contact lenses are generally difficult to clean such as cleaning, and many people prefer to wear spectacle lenses without the hassle of cleaning.

The present invention has been made in order to solve such a problem, and an object of the present invention is to improve the correction effect of blue vision more than a conventional blue vision correction lens, and to further reduce the effect. Another object of the present invention is to provide a spectacle lens for a lens extractor, which can provide a free color tone.

[Means for Solving the Problems] An object of the present invention is to provide a synthetic resin lens containing an ultraviolet absorber having three benzene rings and two azo groups, and these benzene rings are linked via an azo group. Is dyed using a yellow disperse dye composed of an aromatic compound and a blue disperse dye, each of which is linked to each other. The transmittance at a wavelength of 400 nm ranges from 2 to 7%, and the transmittance at a wavelength of 450 nm. Lens extraction characterized in that the range from 3 to 45%, the transmittance from 400 nm to 450 nm increases almost linearly with increasing wavelength, and the transmittance from 75 nm to 450 nm is 75% or less. Achieved by eyeglass lenses.

 Hereinafter, the present invention will be described in detail.

The spectacle lens for the lens extractor of the present invention may be a spectacle lens used together with the intraocular lens and the contact lens when the lens is extracted in cataract surgery and the intraocular lens and the contact lens are inserted. A cataract lens may be used without removing an intraocular lens or a contact lens after removing a lens in cataract surgery.

In the present invention, as a monomer for obtaining a synthetic resin lens, a monomer having diethylene glycol bisallyl carbonate as a main component may be mentioned, but other monomers such as acrylates may be used as long as they form a plastic lens by polymerization. Monomers can also be used.

In the present invention, there are various ultraviolet absorbers added to the synthetic resin lens monomer,
2'-dihydroxy-4-methoxybenzophenone is particularly preferred, and its amount is preferably 0.01 to 4% by weight, particularly preferably 0.1% by weight, based on the synthetic resin lens monomer.
1 to 2% by weight. The reason is that if it is less than 0.01% by weight, the effect of diminishing ultraviolet light is weak, and if it exceeds 4% by weight, the lens becomes brittle, which is not preferable in moldability.

A synthetic resin lens containing an ultraviolet absorber can be obtained by adding the above-mentioned ultraviolet absorber to the above-mentioned monomer and then polymerizing by various polymerization methods such as casting polymerization. Further, after the above-mentioned monomer is polymerized by various polymerization methods such as cast polymerization to obtain a synthetic resin lens, the synthetic resin lens is immersed in a solution containing an ultraviolet absorber to form a synthetic resin lens containing ultraviolet rays. You may get it.

In the present invention, as a yellow disperse dye, an aromatic compound having three benzene rings and two azo groups, and these benzene rings are connected to each other via an azo group, is used. As an example, Are indicated. The reason why the yellow disperse dye was limited to the above-defined one is that the specific yellow disperse dye was used together with the blue disperse dye to dye the lens, as is apparent from the examples described later. This is because, in this case, an absorption curve similar to that of a human eye lens is shown for light in a wavelength range of 380 to 450 nm.

It is not preferable to use a yellow disperse dye other than those described above. The reason is that when a lens is dyed using a yellow disperse dye other than the above, together with a blue disperse dye, for light in a wavelength range of 420 to 450 nm, it exhibits an absorption curve similar to that of the human eye lens. , Wavelength range 380-420
For light of nm, it does not show the shape of the absorption curve similar to the human eye lens, so correction of blue vision is not completely done,
This is because the color tone of the object may not be accurately identified.

In the present invention, the reason for using a blue disperse dye,
When used together with the above-mentioned yellow disperse dye, light having a wavelength of 380 to 450 nm has the same absorption curve as that of the human eye lens, and has an antiglare effect for light having a wavelength of 450 nm or more.

Examples of the blue disperse dye used in the present invention include monoazo, disazo, anthraquinone, nitro, styryl, methine, allylenebenzimidacoumarin, quinonaphthalone, and tamarin disperse dyes.

The spectacle lens for lens extractor according to the present invention has the following two requirements as essential requirements regarding its spectral transmittance.

(I) The range of the transmittance at a wavelength of 400 nm is 2 to 7%, and the wavelength 4
The transmittance at 50 nm ranges from 30 to 45%, and the transmittance from 400 nm to 450 nm increases almost linearly with increasing wavelength.

(Ii) The transmittance from a wavelength of 450 nm to 600 nm is 75% or less.

First, the requirement (i) will be described.
Is effective in correcting blue vision by making the transmittance curve in the wavelength range of 400 nm to 450 nm, which is important for blue vision correction, very similar to the transmittance curve in the same wavelength range of the human lens. This is to prevent retinal damage from light rays. To further explain this point, the range of the transmittance at a wavelength of 400 nm is limited to 2 to 7%. When the transmittance at 400 nm is less than 2% or more than 7%, the human eye lens at the same wavelength is reduced. This is because it is different from the transmittance, which is not preferable. Also 45
The range of the transmittance at 0 nm is limited to 30 to 45% because the wavelength 4
If the transmittance at 50 nm is more than 45%, the correction of blue vision is incomplete due to its poorer light absorption function than the human lens, and it also prevents retinal damage from visible light of short wavelength. On the other hand, if the transmittance at a wavelength of 450 nm is less than 30%, the transmittance of the human eye lens at the same wavelength is lower, which is not preferable. If the transmittance at a wavelength of 450 nm is less than 30%, only a limited color tone is obtained, which is not preferable in that it lacks fashionability.

Furthermore, the reason for limiting the transmittance from 400 nm to 450 nm to increase almost continuously as the wavelength increases is that
This is because the transmittance curve of the human eye lens continuously increases in the same wavelength range, and if it does not continuously increase, the transmittance will be different from the increase in the transmittance of the human eye lens.

Next, requirement (ii) will be explained.
Is for reducing the light of 450 nm or more to have an antiglare effect. That is, the reason for limiting the transmittance from a wavelength of 450 nm to 600 nm to 75% or less is that if the transmittance in the same wavelength region exceeds 75%, the light dimming effect of light of 450 nm or more, that is, the antiglare effect is weak, and occupational This is because it may hurt the eyes of people who are unavoidably exposed to strong sunlight.

In the spectacle lens for lensectomy of the present invention, together with the yellow disperse dye and blue disperse dye,
To provide various free tones by using at least one disperse dye selected from red, pink, and orange disperse dyes to the extent that the blue-eye correction effect is not impaired as necessary. Can be obtained, and color tone variations can be provided. Red, pink and orange disperse dyes such as monoazo, disazo, anthraquinone, nitro, styryl, methine, alylene benzimidacoumarin,
Examples include quinonaphthalone-based and coumarin-based disperse dyes. However, even when these optional dyes are used, it is necessary to satisfy the above requirement (ii) that the transmittance from a wavelength of 450 nm to 600 nm is 75% or less in order to produce a free color tone.

There are two methods for coloring the lens: a method in which several kinds of disperse dyes are put in the same dyeing tank in advance so that a desired color is obtained when the lenses are colored, and a method in which one kind of disperse dye is put in each. There is a method of successively immersing in a dyeing tank, but the method is not particularly limited.

In the manufacture of eyeglass lens for lensectomy of the present invention,
The staining conditions of the lens are different depending on each elemental technique such as the staining concentration, the staining temperature and the immersion time. However, from the reproducibility of the staining, the staining concentration is 0.01 to 5% by weight in the total amount of the dye used, and the immersion time is 30%. The dyeing concentration is preferably 60 to 100 ° C. for seconds to 30 minutes.

Further, by forming a surface hardened film and other functional films on the obtained spectacle lens, surface modification can be performed to impart new properties. For example, polyfunctional acrylate or methacrylate-based UV cured coating or silicone-based, or impart abrasion resistance thermosetting coating _{melamine, SiO, SiO 2, TiO,} CeF 3, CeO 2,
ZrO ₂ , MgF ₂ , MgO, etc. are formed as a single layer or a plurality of layers by an evaporation method to form an antireflection film, or an acrylate or methacrylate elastomer, a styrene elastomer or a urethane elastomer is applied to impart impact resistance,
Further, antifogging property, antifouling property, antistatic property and the like can be imparted by a known method. In addition, these functions
It is also possible to combine more than one kind.

EXAMPLES Hereinafter, examples of the present invention will be described in detail, but the present invention is not limited to these examples.

<Example 1> Diethylene glycol bisallyl carbonate as a monomer for a synthetic resin lens and an ultraviolet absorber
2,2'-Hydroxy-4-methoxybenzophenone and 99.85% by weight of the former and 0.15% by weight of the latter were sufficiently stirred and mixed with a stirrer, and diisopropyl peroxycarbonate (IPP) was used as a polymerization initiator by weight. With monomer 1
The mixture was added and stirred at a ratio of 3 to 00 to obtain a mixed solution. next,
The mixed solution is poured into a lens mold composed of a glass mold and a resin seal, and heated and polymerized in an electric furnace to produce a synthetic resin lens containing an ultraviolet absorber (lens parameter −6.00 to + 2.00D). Obtained.

Next, as a dye, (1) a yellow disperse dye (the dye of the above formula (I)) Dianix Yellow 5RE (manufactured by Mitsubishi Chemical Co., Ltd.) (2) a blue disperse dye Dianix Blue GRE (Mitsubishi Chemical ( 3 g each, water 1 and a surfactant (squirt stabilizer manufactured by Hoya Co., Ltd.) 2 g were added to each of them to prepare two kinds of dyeing solutions, and then the ultraviolet absorption obtained above was obtained. The synthetic resin lens containing the agent is immersed in a DIANIX yellow 5RE staining solution at a staining temperature of 85 ° C. for 3 minutes, and then in a DIANIX blue GRE staining solution at a staining temperature of 85 ° C. for 6 minutes to produce a brown-colored eyeglass lens. Obtained.

The spectral transmittance curve of the spectacle lens of this example of a brown color (measured using a 340 recording spectrophotometer manufactured by Hitachi, Ltd .; the same applies hereinafter) is as shown by a solid line a in FIG.

According to the spectral transmittance curve shown by the solid line a in FIG. 1, the spectacle lens of this embodiment has the following ultraviolet light shielding performance and visible light attenuating performance.

That is, almost 100% in the ultraviolet region (below about 380 nm)
Light blocking rate close to

 Next, the visible light region (about 380 to 780 nm) will be described.

The dashed line e in FIG. 1 is Ophthalmol. 1 , 77 (1962)
1 is an example of a transmittance curve of a human eye lens at the age of 53 shown in FIG. Comparing the transmittance curve of the solid line a of FIG. 1 obtained for the spectacle lens of the present example with the transmittance curve of the dashed line e of FIG. 1 obtained for the human lens, a wavelength range of 400 to 450 nm It can be seen from the graph that the shape of the transmittance curve indicated by the solid line a and the shape of the transmittance curve indicated by the alternate long and short dash line e almost coincide with each other, and that the transmittance in the wavelength range of 450 nm to 600 nm is 70% or less. Therefore, when an intraocular lens or contact lens insert of about 50 to 55 years old wears the spectacle lens of the present embodiment, even if the intraocular lens and the contact lens do not contain an ultraviolet absorber or a pigment, ultraviolet rays and visible light Thus, the eyes were protected, blue vision was corrected, and an antiglare effect was also observed.

<Example 2> A synthetic resin lens (lens parameter -6.00 to + 2.00D) containing an ultraviolet absorber was obtained by the same monomer composition and polymerization method as in Example 1.

Next, as a dye, (1) a yellow disperse dye (the dye of the above formula (I)) Dianix Yellow 5RE (manufactured by Mitsubishi Kasei Co., Ltd.) (2) a red disperse dye Dianic Thread ACE (Mitsubishi Kasei Corp. (3) Orange-based disperse dye Resorin Orange 3GL (manufactured by Bayer) (4) Blue-based disperse dye Dianix Blue RNE (manufactured by Mitsubishi Kasei Corporation) was used in an amount of 3 g each. After adding 2 g of surfactant (Hoya Stabilizer manufactured by Hoya Co., Ltd.) to prepare four types of dyeing solutions, the synthetic resin lens containing the ultraviolet absorbent obtained above was dyed at a temperature of 85 ° C. with the Dyanix Yellow 5RE dyeing solution. For 3 minutes, then Dyanix Blue
Dipped in RNE staining solution at a staining temperature of 85 ° C for 4 minutes, further immersed in Dianic thread ACE staining solution at a staining temperature of 85 ° C for 3 minutes, and then in a resolin orange 3GL staining solution at a staining temperature of 85 ° C for 1 minute.
A spectacle lens of this example having a brownish color was obtained.

The spectral transmittance curve of this spectacle lens is as shown by the solid line b in FIG. In other words, almost 100% in the ultraviolet region
In the wavelength range of 400 to 450 nm, the shape of the transmittance curve of the solid line b for the spectacle lens of the present example and the shape of the transmittance curve of the dashed line e for the human eye lens are substantially the same. It can be seen that the transmittance in the wavelength range of 450 nm to 600 nm is 60% or less. Therefore, it can be seen that the spectacle lens of the present embodiment protects the eyes from ultraviolet rays and visible light, can correct blue vision, and has an antiglare effect, similarly to the spectacle lens of Example 1. .

Example 3 By the same monomer composition and polymerization method as in Example 1, an ultraviolet absorber-containing cataract lens (lens parameters +5.00 to + 15.00D) was obtained.

Next, as a dye, (1) a yellow disperse dye (the dye of the above formula (I)) Dianix Yellow 5RE (manufactured by Mitsubishi Kasei Co., Ltd.) (2) a red disperse dye Dianic Thread ACE (Mitsubishi Kasei Corp.) (3) Orange-based disperse dye Dianix Orange BSE (manufactured by Mitsubishi Kasei Co., Ltd.) (4) Blue-based disperse dye Dianix Blue ACE (manufactured by Mitsubishi Kasei Co., Ltd.) is used in an amount of 3 g each, and water is used for each of these. 1. After adding 2 g of surfactant (Hoya Stabilizer manufactured by Hoya Co., Ltd.) to prepare four kinds of dyeing solutions, the above-obtained ultraviolet absorbent-containing cataract lens is converted to Dynamix Yellow 5R.
E Dyeing solution for 3 minutes at 85 ℃
2 minutes at 85 ° C staining temperature in CE staining solution, 2 minutes at 85 ° C staining temperature in Dianix orange BSE staining solution, 4 minutes and 30 seconds at 85 ° C staining temperature in Dianix Blue ACE staining solution, green-based A colored catalytic lens was obtained. The spectral transmittance curve of the cataract lens of this embodiment is shown by a solid line c in FIG.
As shown in FIG. That is, in the ultraviolet region, almost 100
%, And the shape of the transmittance curve of the solid line c for the spectacle lens of the present example and the shape of the transmittance curve of the dashed line e for the human eye lens in the wavelength range of 400 to 450 nm are substantially the same. It can be seen that the transmittance in the wavelength range of 450 nm to 600 nm is 55% or less. Therefore, similarly to the spectacle lens of the first embodiment, the spectacle lens made of the cataract lens of the present embodiment protects the eyes from ultraviolet rays and visible light, can further correct blue vision, and also provides an antiglare effect. You can see that it is done.

<Example 4> A synthetic resin lens containing an ultraviolet absorber (lens parameter −) was prepared in the same monomer composition and polymerization method as in Example 1.
6.00 to + 2.00D).

Next, as a dye, (1) a yellow disperse dye (the dye of the above formula (I)) Dianix Yellow 5RE (manufactured by Mitsubishi Kasei Co., Ltd.) (2) a red disperse dye Dianic Thread ACE (Mitsubishi Kasei Corp.) (3) Orange-based disperse dye Resorin Orange 3GL (manufactured by Bayer) (4) Blue-based disperse dye Sumicaron Blue EBL (manufactured by Sumitomo Chemical Co., Ltd.) was used in an amount of 3 g each. Add 2 g of activator (Squirt Stabilizer manufactured by Squirt Co., Ltd.) and add 4 g
After preparing the seed dyeing solution, the ultraviolet absorbent-containing cataract lens obtained above was converted to Dynamix Yellow 5RE.
Staining solution at 85 ° C for 3 minutes, then Dyanic Red ACE staining solution at 85 ° C for 2 minutes, and Resorin Orange 3GL staining solution at 85 ° C for 1 minute, then Sumicaron Blue EBL The glass was immersed in the dyeing solution at a dyeing temperature of 85 ° C. for 1 minute and 30 seconds to obtain a brownish spectacle lens. The spectral transmittance curve of the spectacle lens of this embodiment is as shown by the solid line d in FIG. That is, in the ultraviolet region, it has a light blocking ratio close to 100%, and the dashed line e of the human eye lens in the shape of the transmittance curve of the solid line d for the spectacle lens of the present embodiment in the wavelength range of 400 to 450 nm. The shapes of the transmittance curves almost match, and the transmittance in the wavelength range of 450 nm to 600 nm is
It turns out that it is 75% or less. Therefore, similarly to the spectacle lens of the first embodiment, the spectacle lens of the present embodiment protects the eyes from ultraviolet rays and visible light, can further correct blue vision, and has an antiglare effect. Recognize.

Comparative Example The same ultraviolet absorbent-containing synthetic resin lens as in Example 1 was obtained using the same monomer composition and polymerization method as in Example 1.

Next, as the dyes, (1) yellow disperse dye (not included in the yellow disperse dye specified in the present invention) Dyanix Yellow YL-SE (manufactured by Mitsubishi Chemical Corporation) (2) red disperse dye Nick Red ACE (manufactured by Mitsubishi Kasei) (3) Orange disperse dye Resorin Orange 3GL (manufactured by Bayer) (4) Blue disperse dye Dianix Blue RNE (manufactured by Mitsubishi Kasei) 3 g each 1 g of water and 2 g of a surfactant (Hoya Co., Ltd. Joya Stabilizer)
After preparing the seed dyeing solution, the ultraviolet absorbent-containing synthetic resin lens obtained above was applied to the Dyanix Yellow YE-SE dyeing solution at a dyeing temperature of 85 ° C. for 3 minutes, and then Dianix Blue.
Dipped in RNE staining solution at a staining temperature of 85 ° C for 4 minutes, further immersed in Dianic thread ACE staining solution at a staining temperature of 85 ° C for 3 minutes, and then in a resolin orange 3GL staining solution at a staining temperature of 85 ° C for 1 minute.
A brown-colored eyeglass lens was obtained. The spectral transmittance curve of the spectacle lens of this comparative example of a brown color is as shown by a solid line f in FIG.

That is, in the ultraviolet region, a light blocking ratio close to 100% can be obtained, but the wavelength range of 380 nm compared with an example of the transmittance curve of the human eye lens at the age of 53 shown by the dashed line e in FIG.
From 450 to 450 nm, it was found that the shape of the transmittance curve was different, which was insufficient for correcting blue vision.

[Effects of the Invention] As described above, according to the present invention, it is possible to provide a spectacle lens that is extremely effective for correcting blue vision and has an antiglare effect. Further, the spectacle lens of the present invention can freely produce colors and is excellent in fashion.

[Brief description of the drawings]

FIG. 1 is a transmittance curve diagram of a spectacle lens according to an embodiment of the present invention,
FIG. 2 is a transmittance curve of a spectacle lens of a comparative example.

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Claims (1)

(57) [Claims] 1. An aromatic compound having a synthetic resin lens containing an ultraviolet absorber having three benzene rings and two azo groups, and these benzene rings are connected to each other via an azo group. Is dyed using a yellow disperse dye and a blue disperse dye. The transmittance at a wavelength of 400 nm ranges from 2 to 7%, and the transmittance at a wavelength of 450 nm ranges from 3 to 3.
A lens extractor characterized in that the transmittance from 400 nm to 450 nm increases almost linearly with increasing wavelength at 0 to 45%, and the transmittance from 450 nm to 600 nm is 75% or less. For spectacle lenses.