JP2572222Y2 - Pipette equipment - Google Patents

Description

[Detailed description of the invention]

[0001]

BACKGROUND OF THE INVENTION The present invention relates to an automatic biochemical analyzer for automatically performing a biochemical reaction or an immune reaction of a blood sample, and a pipette device comprising a plurality of pipettes for continuously dispensing blood samples and reagents. About.

[0002]

2. Description of the Related Art Conventionally, in a pipette apparatus, a plurality of pipette nozzles have been described, for example,
No. 6030 discloses a structure in which a plurality of pipettes held by a turret-shaped pipette holder are intermittently rotated from a sample suction position to an emergency sample position and further from a sample dispensing position to a pipette washing position. However, it is impossible to control a plurality of pipette nozzles simultaneously at different liquid levels for each intermittent rotation in order to perform up / down driving with a single upper / lower shaft through a plurality of upper / lower sliders. Certain disadvantages were found.

[0003]

SUMMARY OF THE INVENTION As described above, in a pipette device having a plurality of pipes, a pipetting apparatus is disclosed.
Taking the example of No. 46030, in a device that intermittently rotates from the sample aspirating position, emergency sample position, and further from the sample dispensing position to the pipette washing position, suction and dispensing at each position are performed for each pipette nozzle. With the conventional method, the conventional method can only drive to the same pipette nozzle position. In some cases, the suction amount is insufficient or impossible, and in other cases, the disadvantage that the nozzle penetrates too deeply into the liquid surface is eliminated. It was aimed at.

[0004]

According to the present invention, in order to solve the above-mentioned drawbacks, in a pipette apparatus having a plurality of pipette nozzles on the same rotary shaft, individual vertical shafts are provided for each pipette nozzle. A liquid level sensor having upper and lower strokes for each pipette nozzle at a predetermined rotation position by means of an upper and lower slider detects the liquid level at the rotation position to thereby perform the upper and lower strokes for each pipette nozzle. It is possible to control each time.

[0005]

The pipetting apparatus has a plurality of pipette nozzles, and the dispensing of the sample, the dilution of the sample, the dispensing of the diluent, and the washing of the pipette nozzle are performed for each rotation. For rotation, a rotation motor and gears are driven, and each pipette nozzle is rotated together with the arm, and its slide bush is inserted into upper and lower hooks arranged at 90 ° intervals, and is passed through each vertical shaft. The upper and lower motors are driven, and the liquid level is detected by the function of the liquid level detection sensor arranged in parallel with each pipette nozzle. Dispensing, dilution and cleaning for each nozzle can be performed easily and quickly one after another. It has become.

[0006]

1 and 2, an embodiment of the present invention will be described. The pipette mechanism is provided with four independent pipette nozzles 1, 1 ', 1 ", 1"', and is intermittently rotated around the central axis 12 by 90 ° by a rotation mechanism using a rotation motor 2 and a rotation gear 3. Rotate. Cassette A at position A
The sample 5 is further aspirated, the sample is diluted at the position B rotated by 90 °, the diluted sample is dispensed into the reaction tubes 6 at the position C further rotated by 90 °, and the sample is diluted at the position D further rotated by 90 ° Clean the pipette nozzle, rotate 90 °
Return to the sample suction position. When the pipette 1, 1 ',... Is UP, the pipette rotates and stops at the reference position. The stop position at that time rotates clockwise in the direction of the arrow.

The rotation is performed by the arms 7, 7 ', 7 ", 7"'.
Are rotated together with the pipettes 1, 1 ', the liquid is supplied to the rotating part by the rotary valve 8, the power is supplied to the rotating part by the slip ring 9, and the rotation is involved. Rotation of 90 ° is performed and pipettes 1, 1
., The slide bush portions 10, 10 'and the upper and lower hooks 11, 11' are fitted into the arms 7, 7 '. Thereafter, each of the upper and lower motors 13, 13 ',
13 ″ are driven and slide shafts 16 and 16 ′ for up and down
The vertical movement of the vertical shafts 14, 14 ′ is performed through.

The pipette 1 located at the sample position A descends to detect the liquid level of the sample by the operation of the sensor 15 and stops the motor 13 for up and down. Similarly, the pipette 1 'at the diluted sample position B descends, similarly operates the independent liquid level sensor 15', stops the linked vertical motor 13 ', and thereafter dilutes the sample 5 at the position A and the dilution at the position B. Sample (not shown)
And the pipette nozzle 1 'rises. The pipette nozzle 1 '' arriving at the position C is sequentially dispensed into the reaction tube 6 by the same operation, but has an independent liquid level sensor 15 '',
At the same time, the independent vertical motor 13 '' is operated. Similarly, at the cleaning position, the operation of the liquid level sensor 15 "" and the operation of the vertical drive motor 13 "" are operated to complete the cleaning operation of the pipette nozzle 1 "". This vertical movement is performed by an independent vertical drive mechanism, so that each pipette nozzle 1, 1 ', 1'
, 1 ′ ″ can independently perform operations such as liquid suction and dispensing simultaneously with an arbitrary stroke. When the above operation is completed, the pipettes 1, 1 ',... Rotate by 90 degrees and shift to the next operation.

[0009]

The pipette device according to the present invention has a plurality of pipette nozzles on the same rotation axis, and enables simultaneous and arbitrary vertical movement of a stroke at a predetermined rotation position. Independent vertical movement enables detection of different liquid levels, individual suction, dispensing, washing, etc., for each pipette.

[Brief description of the drawings]

FIG. 1 is an explanatory view of a driving mechanism of the pipette device according to the present invention.

FIG. 2 is an explanatory view for operating the pipette device according to the present invention.

[Explanation of symbols]

 Reference Signs List 1 pipette nozzle 1 'pipette nozzle 2 rotation motor 3 rotation gear 4 cassette 5 specimen 6 reaction tube 7 arm 7' arm 10 slide bush 10 'slide bush 11 up / down hook 11' up / down hook 12 center axis 13 up / down motor 13 ' Vertical motor 14 Vertical axis 14 'Vertical axis 15 Sensor 15' Sensor 16 Vertical slide axis 16 'Vertical slide axis

Claims (1)

(57) [Scope of request for utility model registration] 1. A pipetting mechanism for a biochemical automatic analyzer, comprising: a plurality of pipette nozzles on a same rotation axis;
A pipetting apparatus, wherein a plurality of pipette nozzles can simultaneously move up and down with an arbitrary stroke at a predetermined rotation position.