JP2511782Y2 - Medical patch - Google Patents

Description

[Detailed description of the invention] [Industrial application field] The invention relates to a medical patch.

[Conventional technology]

Conventionally known adhesive patches containing an adhesive base and a drug, and a medical patch comprising a support layer backed by and supporting the adhesive base layer, both layers are manufactured. They were laminated and integrated with the same shape and the same area.

[Problems to be solved by the device]

Since the conventional medical patch has the above-mentioned structure, it has some problems as follows. That is, the drug or the like in the adhesive plaster is absorbed in the backing support layer or the peelable protective sheet during storage, or penetrates both to be dissipated to the outside of the system and has a hepatorenal pharmacological effect at the time of application. Diminishes or disappears. In particular, the tendency was greater when the backing support layer was porous or fibrous and was desirable as the backing support layer itself. In addition, since the degree of migration to the adjacent layer differs depending on the type of drug, there is a constraint that the drug must be selected in consideration of this. Half
Many non-absorbent and non-permeable materials such as PET are rigid and lack in softness, and are not suitable as a backing support layer.

Further, since the adhesive plaster layer and the backing support layer have the same shape and area and the peripheral edges thereof are completely coincident with each other, it is not possible to prevent stains from the exposed portion of the adhesive layer on the peripheral edge during use. This was more remarkable as the thickness of the adhesive plaster layer was thicker and softer.

An object of the present invention is to provide a medical patch which can guarantee the pharmacological effect at the time of application without the drug in the adhesive plaster layer escaping during storage and which is free from the risk of stain on the periphery. is there.

[Means for solving the problem]

In order to achieve the above-mentioned object, the medical patch according to the present invention is coated on both sides of an adhesive plaster layer containing an adhesive base and a drug, and absorbs the drug etc. And a peelable protective sheet that does not penetrate, and an adhesive plaster layer backing support layer that is releasably attached to either one of the both coated peelable protection sheets. The planar shape and area are such that the adhesive plaster layer can be positioned inside the periphery thereof.

In this specification, "medicine, etc." means, in addition to a drug,
A plasticizer, a stabilizer and a percutaneous absorption enhancer contained in the adhesive plaster layer.

The releasable protective sheet that does not absorb and permeate a drug or the like can be obtained by selecting a sheet material itself having such properties, or by applying an absorption / permeation inhibitor to the sheet.

The planar shape of the adhesive plaster layer, the double-peelable protective sheet and the adhesive plaster layer backing support layer is usually a rectangle, but of course the shape is not limited to this, and may be a polygon, a circle, an ellipse or the like. .

Further, the adhesive plaster layer may be divided into two layers via a peelable protective sheet, as described in Examples below.

Further, the both coating peelable protective sheets may be obtained by folding one sheet into two, as will be described later in Examples. Further, the peelable protective sheet is preferably thick and has a rigid property such as less bending, bending, twisting and stretching than the backing support layer. If there are two peelable protective sheets,
Of these, at least the peelable protective sheet on the side supporting the backing support layer is preferably transparent or translucent so that the affected area can be confirmed and the application position can be confirmed.

[Action]

The medical patch according to the present invention comprises an adhesive plaster layer containing an adhesive base and a drug, and a peelable protective sheet that is coated on both sides of the adhesive plaster layer and does not absorb or permeate the drug, Since it is provided with an adhesive plaster layer backing support layer that is releasably attached to either one of both releasable protective sheets, it can be applied to the affected area by the following two methods. . That is, one of them is that the peelable protective sheet on the side without the backing support layer is first peeled off, and then the adhesive plaster layer is attached to the affected area, whereby the other peelable protective sheet is supported by the backing support. Peel it off with the body layer and turn it over,
The backing support layer is pressed from the top of the adhesive plaster layer and adhered thereto, and finally the peelable protective sheet which is present by changing the position on the surface is peeled off from the backing support layer.

The other one is that the peelable protective sheet on the side having the backing support layer is first peeled off together with the backing support layer and turned over, and the backing support layer is pressed down from above the adhesive plaster layer. After applying, peel off one of the peelable protective sheets from the adhesive plaster layer, and then apply the adhesive plaster layer to the affected area, then change the position on the surface and line the other peelable protective sheet It is to be peeled off from the support layer.

During storage of the medical patch, the adhesive plaster layer is sandwiched between the backing support layer and the adhesive plaster layer by a peelable protective sheet that does not absorb and permeate drugs and the like. Since one of the peelable protective sheets is interposed, the medicine or the like does not escape from the adhesive plaster layer.

Therefore, the backing support layer does not absorb the drug or the like of the adhesive plaster layer.

In addition, since the planar shape and area of the backing support layer are such that the adhesive plaster layer can be positioned more inside than its periphery, the adhesive plaster can be used for backing during application and during use. It does not flow out or spill out of the support layer.

〔Example〕

Example 1 This example is shown in FIG. 1 and FIG. 2, and the medical patch of the same figure shows an adhesive plaster layer (1) containing an adhesive base and a drug, and an adhesive plaster. Releasable protective sheets (2) and (3) that are coated on both sides of the agent layer (1) and do not absorb and permeate medicines, etc. And a support layer (4) for backing the adhesive plaster layer, and the planar shape and area of the backing support layer (4) can position the adhesive plaster layer (1) inside the periphery thereof. It has such a shape and size.

In addition, one of the methods for sticking to the affected area during use is shown in FIGS. 2 to 7, and the other is shown in FIGS. 8 to 11.
It is shown in the figure.

That is, one of them is that the peelable protective sheet (3) on the side without the backing support layer (4) is first peeled off (third
Fig.), And then after sticking the adhesive plaster layer (1) to the affected area (D) (Fig. 4), the other peelable protective sheet (2) together with the backing support layer (4) The peelable protective sheet (2) is peeled off and turned over, and the backing support layer (4) is pressed from the top of the adhesive plaster layer (1) to be adhered thereto, and finally the surface is changed in position to be present. Is peeled off from the backing support layer (4).

The other one is that the releasable protective sheet (2) on the side having the backing support layer (4) is first peeled off together with the backing support layer (4) (Fig. 8), and it is turned over and the backing support layer ( 4) is pressed from above the adhesive plaster layer (1) and adhered thereto (Fig. 9), and then one of the peelable protective sheets (3) is peeled from the adhesive plaster layer (1) ( (Fig. 10), then, after sticking the adhesive plaster layer (1) to the affected area (D) (Fig. 11), the other peelable protective sheet (2) which is present at different positions on the surface is used as a backing support. It is to be peeled from the body layer (4) (Fig. 7).

Example 2 This example is shown in FIG.
The two peelable protective sheets (2) and (3) in (1) are integrally connected at the horizontal U-shaped connecting portion. That is, a peelable protective sheet (5a) (5b) coated on both sides of the adhesive plaster layer (1) is obtained by bending one sheet of the peelable protective sheet (5) into a hairpin cross section. It is a thing.

Example 3 This example is shown in FIG.
The adhesive plaster layer (1) in (1) is divided into two layers.

That is, the adhesive plaster layer (11) is divided into a first layer (11a) and a second layer (11b), and an intermediate peelable protective sheet (6) is interposed between both layers.

When the compositions of the first layer (11a) and the second layer (11b) are different and both layers are integrated layers as in Examples 1 and 2, both layers are stored during long-term storage. It is desirable to adopt this embodiment when there is a possibility that phenomena such as deterioration of the adhesive plaster layer and deterioration of drug efficacy may occur due to the contact with the adhesive.

For example, the first layer (11a) may be supersaturated with a drug, and the second layer (11b) directly applied to the skin may contain a percutaneous absorption enhancer, a skin irritation suppressant or emollient at a high ratio. Moreover, the composition of the adhesive base is such that the first layer (11a) can be compatible with the drug in a high content and does not deteriorate the properties for a long period of time, and the second layer (11b) can be applied to the skin. By having a composition that adheres well, has minimal irritation to the skin, and allows a drug to easily pass therethrough, the effectiveness as a patch can be enhanced.

In using the medical patch of this example, for example, the upper peelable protective sheet (5) is temporarily separated while separating the intermediate peelable protective sheet (6) and the second layer (11b).
a) is opened, and the intermediate peelable protective sheet (6) is placed on the first layer (11
After peeling and removing from a), the peelable protective sheet (5a) is closed again. Then, the first layer (11a) and the second layer (11a)
and b) are adhered to each other to form one adhesive plaster layer (11) as a whole. Its structure is the same as that of the second embodiment. In addition, between the intermediate peelable protective sheet (6) and the first layer (11a), between the lower peelable protective sheet (5b) and the second layer
A method of starting peeling from between the layer (11b) and the like may be used. The point is that the state shown in FIG. 7 should be finally set, and there are several methods. Which method is selected among them is arbitrary, but it may be peeled from the interface having the smallest peeling force, for example, depending on the magnitude relation of the interlayer peeling force at each interface.

In addition, FIG. 14 shows a state in which one medical patch is enclosed in the packaging bag (7). Although the one of the first embodiment is enclosed here, the one of the second or third embodiment may be used. In the figure, (7a) and (7b) are respectively bag material layers forming both surfaces of the packaging bag (7), and both may be the same material or different materials. (8) is a seal portion extending over the entire peripheral edge portions of both layers (7a) and (7b), and (9) is an opening tab.

[Effect of device]

According to the medical patch of the present invention, the adhesive plaster layer is sandwiched on both sides by a peelable protective sheet that does not absorb and permeate drugs and the like, and a backing support layer and an adhesive plaster layer are provided. Since one peelable protective sheet is interposed between the two, even if the medical patch is stored for a long period of time or under severe conditions such as high temperature, the drug etc. in the adhesive plaster layer will not , Don't dissipate outside of it. Therefore, the medicinal effect will never decline.

Further, since there is no migration of the plasticizer or the like in the adhesive plaster layer to the backing support layer, there is no change in the physical properties of the backing support layer during the storage, and there is no migration of the drug, etc. A very soft plastic film, a porous sheet, a fibrous or fibrous sheet, or a laminate of these, which cannot be used because it is easy to use, can be freely selected and used as a suitable backing support layer.

In addition, since the adhesive plaster does not flow out or squeeze out of the backing support layer during application and during use, the periphery of the medical patch can be kept clean without being contaminated. When removing the adhesive patch from the affected area, it is possible to pick up the peripheral part of the backing support layer where the adhesive plaster layer does not exist, and lift it up. It has the advantage of being easy.

[Brief description of drawings]

1 and 2 show Embodiment 1 of the present invention.
Fig. 1 is a partially cutaway perspective view, and Fig. 2 is Fig. 1 II-II.
3 to 7 are longitudinal sectional views sequentially showing one of the methods for sticking the medical patch shown in Example 1 to the affected area, and FIGS. It is a longitudinal section showing the method one by one. 12 and 13 are sectional views corresponding to FIG. 2 showing Embodiment 2 and Embodiment 3, respectively. FIG. 14 is a longitudinal sectional view showing a state in which the medical patch of Example 1 is contained in a packaging bag. (1) (11) ... Adhesive plaster layer, (2) (3) (5a)
(5b) …… Releasable protective sheet, (4) …… Supporting backing layer.

Claims (1)

(57) [Scope of utility model registration request] 1. An adhesive plaster layer containing an adhesive base and a drug, a peelable protective sheet which is coated on both sides of the adhesive plaster layer and does not absorb or permeate the drug, etc. The protective sheet is provided with an adhesive plaster layer backing support layer that is releasably attached to either one of the protective sheets, and the planar shape and area of the backing support layer is the adhesive plaster layer. A medical patch that is shaped and sized so that it can be positioned inside the surroundings.