JP2025515996A5 - - Google Patents

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Publication number
JP2025515996A5
JP2025515996A5 JP2024560406A JP2024560406A JP2025515996A5 JP 2025515996 A5 JP2025515996 A5 JP 2025515996A5 JP 2024560406 A JP2024560406 A JP 2024560406A JP 2024560406 A JP2024560406 A JP 2024560406A JP 2025515996 A5 JP2025515996 A5 JP 2025515996A5
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JP
Japan
Prior art keywords
seq
nucleic acid
base sequence
strand comprises
acid base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024560406A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025515996A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/065812 external-priority patent/WO2023201362A2/en
Publication of JP2025515996A publication Critical patent/JP2025515996A/ja
Publication of JP2025515996A5 publication Critical patent/JP2025515996A5/ja
Pending legal-status Critical Current

Links

JP2024560406A 2022-04-14 2023-04-14 酵素補充療法を用いたFN3ドメイン-siRNAコンジュゲート Pending JP2025515996A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263330797P 2022-04-14 2022-04-14
US63/330,797 2022-04-14
PCT/US2023/065812 WO2023201362A2 (en) 2022-04-14 2023-04-14 Fn3 domain-sirna conjugates with enzyme replacement therapy

Publications (2)

Publication Number Publication Date
JP2025515996A JP2025515996A (ja) 2025-05-23
JP2025515996A5 true JP2025515996A5 (enExample) 2026-04-20

Family

ID=88330423

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024560406A Pending JP2025515996A (ja) 2022-04-14 2023-04-14 酵素補充療法を用いたFN3ドメイン-siRNAコンジュゲート

Country Status (9)

Country Link
US (1) US20240043844A1 (enExample)
EP (1) EP4507702A2 (enExample)
JP (1) JP2025515996A (enExample)
KR (1) KR20250024745A (enExample)
CN (1) CN119604311A (enExample)
AU (1) AU2023252976A1 (enExample)
CA (1) CA3248570A1 (enExample)
IL (1) IL316071A (enExample)
WO (1) WO2023201362A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119119240A (zh) 2019-10-14 2024-12-13 Aro生物疗法公司 结合cd71的纤维粘连蛋白iii型结构域
CA3214552A1 (en) 2021-04-14 2022-10-20 Russell C. Addis Cd71 binding fibronectin type iii domains
EP4323008A4 (en) 2021-04-14 2026-02-25 Aro Biotherapeutics Company FN3-ARNSI DOMAIN CONJUGATES AND THEIR USES
WO2025231388A1 (en) * 2024-05-03 2025-11-06 Aro Biotherapeutics Company Methods and compositions for treating pompe disease
WO2025245474A1 (en) * 2024-05-23 2025-11-27 Aro Biotherapeutics Company Formulations comprising fn3-sirna conjugates and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005072057A2 (en) * 2004-01-30 2005-08-11 Quark Biotech, Inc. Oligoribonucleotides and methods of use thereof for treatment of fibrotic conditions and other diseases
EA201001734A1 (ru) * 2008-05-02 2011-10-31 Новартис Аг Улучшенные связывающие молекулы на основе фибронектина и их применение
US11781138B2 (en) * 2019-10-14 2023-10-10 Aro Biotherapeutics Company FN3 domain-siRNA conjugates and uses thereof
WO2021226107A1 (en) * 2020-05-05 2021-11-11 Avidity Biosciences, Inc. Compositions and methods of treating pompe disease
EP4323008A4 (en) * 2021-04-14 2026-02-25 Aro Biotherapeutics Company FN3-ARNSI DOMAIN CONJUGATES AND THEIR USES

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