JP2025514489A5 - - Google Patents

Info

Publication number
JP2025514489A5
JP2025514489A5 JP2024564848A JP2024564848A JP2025514489A5 JP 2025514489 A5 JP2025514489 A5 JP 2025514489A5 JP 2024564848 A JP2024564848 A JP 2024564848A JP 2024564848 A JP2024564848 A JP 2024564848A JP 2025514489 A5 JP2025514489 A5 JP 2025514489A5
Authority
JP
Japan
Prior art keywords
bag3
vector
polynucleotide
expression
brain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024564848A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025514489A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/020659 external-priority patent/WO2023215266A1/en
Publication of JP2025514489A publication Critical patent/JP2025514489A/ja
Publication of JP2025514489A5 publication Critical patent/JP2025514489A5/ja
Pending legal-status Critical Current

Links

JP2024564848A 2022-05-03 2023-05-02 脳におけるbag3およびタンパク質品質管理 Pending JP2025514489A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263337914P 2022-05-03 2022-05-03
US63/337,914 2022-05-03
PCT/US2023/020659 WO2023215266A1 (en) 2022-05-03 2023-05-02 Bag3 and protein quality control in the brain

Publications (2)

Publication Number Publication Date
JP2025514489A JP2025514489A (ja) 2025-05-02
JP2025514489A5 true JP2025514489A5 (OSRAM) 2026-05-14

Family

ID=88646932

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024564848A Pending JP2025514489A (ja) 2022-05-03 2023-05-02 脳におけるbag3およびタンパク質品質管理

Country Status (11)

Country Link
US (1) US20250289858A1 (OSRAM)
EP (1) EP4518882A4 (OSRAM)
JP (1) JP2025514489A (OSRAM)
KR (1) KR20250010008A (OSRAM)
CN (1) CN119255814A (OSRAM)
AU (1) AU2023265031A1 (OSRAM)
CA (1) CA3250880A1 (OSRAM)
CL (1) CL2024003318A1 (OSRAM)
IL (1) IL316559A (OSRAM)
MX (1) MX2024013495A (OSRAM)
WO (1) WO2023215266A1 (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4705326A1 (en) * 2023-05-02 2026-03-11 Research Institute at Nationwide Children's Hospital Gene therapy for treatment of protein misfolding diseases
CN120478386B (zh) * 2025-07-18 2025-10-17 南京大学 一种用于预防、改善和/或治疗阿尔茨海默症的siRNA及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1323733A1 (en) * 2001-12-28 2003-07-02 Arturo Leone BAG3 nucleotide and protein sequences to be used in research, diagnostics and therapy for cell death-involving diseases
CA3228845A1 (en) * 2014-01-31 2015-08-06 Temple University Of The Commonwealth System Of Higher Education Bag3 and uses thereof in the treatment of heart failure with reduced ejection fraction
CN109937045A (zh) * 2016-08-11 2019-06-25 天普大学-联邦高等教育系统 局部缺血/再灌注损伤
CN113286588A (zh) * 2018-10-19 2021-08-20 阿克里普斯一有限公司 神经性疾病的治疗
US20220023350A1 (en) * 2018-11-04 2022-01-27 Figene, Llc Treatment of cerebral hypoxia including stroke, chronic traumatic encephalopathy, and traumatic brain injury
WO2020150377A1 (en) * 2019-01-15 2020-07-23 Temple University - Of The Commonwealth System Of Higher Education Targeting the bag family for the treatment of neurodegenerative disease
WO2023069744A1 (en) * 2021-10-22 2023-04-27 Temple University Of The Commonwealth System Of Higher Education Bag3 methods and uses for treatment of inflammation

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