JP2025514180A5 - - Google Patents

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Publication number
JP2025514180A5
JP2025514180A5 JP2024563257A JP2024563257A JP2025514180A5 JP 2025514180 A5 JP2025514180 A5 JP 2025514180A5 JP 2024563257 A JP2024563257 A JP 2024563257A JP 2024563257 A JP2024563257 A JP 2024563257A JP 2025514180 A5 JP2025514180 A5 JP 2025514180A5
Authority
JP
Japan
Prior art keywords
conjugate according
mir
carbohydrate
gene sequence
conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024563257A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025514180A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/019940 external-priority patent/WO2023212027A2/en
Publication of JP2025514180A publication Critical patent/JP2025514180A/ja
Publication of JP2025514180A5 publication Critical patent/JP2025514180A5/ja
Pending legal-status Critical Current

Links

JP2024563257A 2022-04-26 2023-04-26 強化された肝臓及び腎臓特異的標的化のための遺伝子配列-炭水化物コンジュゲート Pending JP2025514180A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263335174P 2022-04-26 2022-04-26
US63/335,174 2022-04-26
PCT/US2023/019940 WO2023212027A2 (en) 2022-04-26 2023-04-26 Genetic sequence-carbohydrate conjugates for enhanced liver- and kidney-specific targeting

Publications (2)

Publication Number Publication Date
JP2025514180A JP2025514180A (ja) 2025-05-02
JP2025514180A5 true JP2025514180A5 (enExample) 2026-05-08

Family

ID=88519558

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024563257A Pending JP2025514180A (ja) 2022-04-26 2023-04-26 強化された肝臓及び腎臓特異的標的化のための遺伝子配列-炭水化物コンジュゲート

Country Status (6)

Country Link
US (1) US20250346895A1 (enExample)
EP (1) EP4514970A2 (enExample)
JP (1) JP2025514180A (enExample)
CN (1) CN119213006A (enExample)
CA (1) CA3256515A1 (enExample)
WO (1) WO2023212027A2 (enExample)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6746868B1 (en) * 1997-09-18 2004-06-08 Isis Pharmaceuticals, Inc. Chemical modification of DNA using peptide nucleic acid conjugates
NZ528966A (en) * 2003-10-17 2006-11-30 Otago Innovation Ltd Peptide nucleic acid conjugates and uses thereof
EP2229186A2 (en) * 2007-12-04 2010-09-22 Alnylam Pharmaceuticals Inc. Carbohydrate conjugates as delivery agents for oligonucleotides
US11833254B2 (en) * 2020-05-27 2023-12-05 University Of Connecticut Discoidal nano universal platform for efficient delivery of PNAs

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