JP2025513664A5 - - Google Patents
Info
- Publication number
- JP2025513664A5 JP2025513664A5 JP2024505118A JP2024505118A JP2025513664A5 JP 2025513664 A5 JP2025513664 A5 JP 2025513664A5 JP 2024505118 A JP2024505118 A JP 2024505118A JP 2024505118 A JP2024505118 A JP 2024505118A JP 2025513664 A5 JP2025513664 A5 JP 2025513664A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- amino acid
- alkyl
- conjugate according
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263322914P | 2022-03-23 | 2022-03-23 | |
| US63/322,914 | 2022-03-23 | ||
| US202263344932P | 2022-05-23 | 2022-05-23 | |
| US63/344,932 | 2022-05-23 | ||
| PCT/US2022/038904 WO2023009835A2 (en) | 2021-07-30 | 2022-10-28 | Antibody conjugates specific for mucin-1 and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025513664A JP2025513664A (ja) | 2025-04-30 |
| JP2025513664A5 true JP2025513664A5 (enExample) | 2025-11-06 |
Family
ID=89834545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024505118A Pending JP2025513664A (ja) | 2022-03-23 | 2022-10-28 | ムチン-1に特異的な抗体コンジュゲート及びその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250152724A1 (enExample) |
| JP (1) | JP2025513664A (enExample) |
| KR (1) | KR20250160368A (enExample) |
| CN (1) | CN120282965A (enExample) |
| AU (1) | AU2022317537A1 (enExample) |
| CA (1) | CA3227975A1 (enExample) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2016001541A (es) * | 2013-08-02 | 2016-08-18 | Sanofi Sa | Uso de anticuerpo inmunoconjugado anti-muc1 maitansinoide para el tratamiento de tumores solidos. |
| CN115504924A (zh) * | 2013-11-27 | 2022-12-23 | 雷德伍德生物科技股份有限公司 | 肼基-吡咯并化合物及用于生成缀合物的方法 |
| AU2015271100B2 (en) * | 2014-06-06 | 2020-07-30 | Redwood Bioscience, Inc. | Anti-HER2 antibody-maytansine conjugates and methods of use thereof |
| WO2017083306A1 (en) * | 2015-11-09 | 2017-05-18 | R.P. Scherer Technologies, Llc | Anti-cd22 antibody-maytansine conjugates and methods of use thereof |
| WO2017194568A1 (en) * | 2016-05-11 | 2017-11-16 | Sanofi | Treatment regimen using anti-muc1 maytansinoid immunoconjugate antibody for the treatment of tumors |
| WO2020096775A1 (en) * | 2018-11-09 | 2020-05-14 | R.P. Scherer Technologies, Llc | Sulfatase-cleavable linkers for antibody-drug conjugates |
| WO2020154437A1 (en) * | 2019-01-23 | 2020-07-30 | R.P. Scherer Technologies, Llc | Glycoside-containing peptide linkers for antibody-drug conjugates |
| CA3156248A1 (en) * | 2019-10-31 | 2021-05-06 | R.P. Scherer Technologies, Llc | ANTI-CD37-MAYTANSINE ANTIBODY CONJUGATES AND METHODS OF USE THEREOF |
-
2022
- 2022-10-28 KR KR1020247006844A patent/KR20250160368A/ko active Pending
- 2022-10-28 AU AU2022317537A patent/AU2022317537A1/en active Pending
- 2022-10-28 CA CA3227975A patent/CA3227975A1/en active Pending
- 2022-10-28 JP JP2024505118A patent/JP2025513664A/ja active Pending
- 2022-10-28 US US18/291,900 patent/US20250152724A1/en active Pending
- 2022-10-28 CN CN202280066194.8A patent/CN120282965A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7403507B2 (ja) | 薬物としてアマトキシンの誘導体を有する抗体薬物コンジュゲート | |
| JP2024096335A (ja) | 親水性抗体-薬物コンジュゲート | |
| DK2678037T3 (en) | Branched linker for protein pharmaceutical conjugates | |
| JP2022530524A5 (enExample) | ||
| JP2025508009A5 (enExample) | ||
| SA516371381B1 (ar) | مواد اقتران عقار جسم مضاد (adcs) مع بروتين مغزل كينسين (ksp) | |
| AU2020234394A1 (en) | Site-specific antibody conjugation and antibody-drug conjugate as specific example thereof | |
| JP2021513844A (ja) | グリピカン3抗体およびそのコンジュゲート | |
| CA3093327A1 (en) | Targeted cd73 antibody and antibody-drug conjugate, and preparation method therefor and uses thereof | |
| RU2007116973A (ru) | Терапевтические средства с пониженной токсичностью | |
| TW201620554A (zh) | 抗her2抗體-藥物結合物 | |
| JP2024501894A5 (enExample) | ||
| CN112601522A (zh) | 抗体-alk5抑制剂偶联物及其用途 | |
| JP2008515889A5 (enExample) | ||
| WO2024227439A1 (zh) | 具有靶向作用的偶联物及其制备方法和用途 | |
| JP2024545170A5 (enExample) | ||
| CN115052663A (zh) | Alk5抑制剂缀合物及其用途 | |
| JP2024529506A5 (enExample) | ||
| CN120957758A (zh) | 大环化合物及其制备方法和用途 | |
| WO2024160176A1 (zh) | 一类连接子药物及其抗体-药物偶联物的制备方法和应用 | |
| JP2025508779A5 (enExample) | ||
| WO2025087323A1 (zh) | B7-h3抗体药物偶联物及其应用 | |
| CN120957759A (zh) | 具有抗肿瘤作用的化合物及其制备方法和用途 | |
| CN119156232A (zh) | 抗体-药物偶联物前体及其合成中间体 | |
| JP2024532677A5 (enExample) |