JP2025512888A5 - - Google Patents

Info

Publication number
JP2025512888A5
JP2025512888A5 JP2024557995A JP2024557995A JP2025512888A5 JP 2025512888 A5 JP2025512888 A5 JP 2025512888A5 JP 2024557995 A JP2024557995 A JP 2024557995A JP 2024557995 A JP2024557995 A JP 2024557995A JP 2025512888 A5 JP2025512888 A5 JP 2025512888A5
Authority
JP
Japan
Prior art keywords
antibody
cancer
seq
antigen
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024557995A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025512888A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/065194 external-priority patent/WO2023192976A1/en
Publication of JP2025512888A publication Critical patent/JP2025512888A/ja
Publication of JP2025512888A5 publication Critical patent/JP2025512888A5/ja
Pending legal-status Critical Current

Links

JP2024557995A 2022-04-01 2023-03-31 ヒトpd-l1およびpd-l2に対する二重特異性抗体ならびにその使用方法 Pending JP2025512888A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263326456P 2022-04-01 2022-04-01
US63/326,456 2022-04-01
US202263378196P 2022-10-03 2022-10-03
US63/378,196 2022-10-03
PCT/US2023/065194 WO2023192976A1 (en) 2022-04-01 2023-03-31 Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor

Publications (2)

Publication Number Publication Date
JP2025512888A JP2025512888A (ja) 2025-04-22
JP2025512888A5 true JP2025512888A5 (https=) 2026-04-07

Family

ID=86185021

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024557995A Pending JP2025512888A (ja) 2022-04-01 2023-03-31 ヒトpd-l1およびpd-l2に対する二重特異性抗体ならびにその使用方法

Country Status (10)

Country Link
US (1) US20230365708A1 (https=)
EP (1) EP4504783A1 (https=)
JP (1) JP2025512888A (https=)
KR (1) KR20240167703A (https=)
AU (1) AU2023243615A1 (https=)
CA (1) CA3246648A1 (https=)
IL (1) IL316011A (https=)
MX (1) MX2024012121A (https=)
TW (1) TW202405011A (https=)
WO (1) WO2023192976A1 (https=)

Family Cites Families (33)

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NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4957939A (en) 1981-07-24 1990-09-18 Schering Aktiengesellschaft Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging
US4867973A (en) 1984-08-31 1989-09-19 Cytogen Corporation Antibody-therapeutic agent conjugates
US4472509A (en) 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4938948A (en) 1985-10-07 1990-07-03 Cetus Corporation Method for imaging breast tumors using labeled monoclonal anti-human breast cancer antibodies
US4680338A (en) 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker
US5824311A (en) 1987-11-30 1998-10-20 Trustees Of The University Of Pennsylvania Treatment of tumors with monoclonal antibodies against oncogene antigens
US5563250A (en) 1987-12-02 1996-10-08 Neorx Corporation Cleavable conjugates for the delivery and release of agents in native form
US5141648A (en) 1987-12-02 1992-08-25 Neorx Corporation Methods for isolating compounds using cleavable linker bound matrices
JPH049249A (ja) 1990-04-27 1992-01-14 Kusuda:Kk 塗型剤吹き付け機
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
WO1994012520A1 (en) 1992-11-20 1994-06-09 Enzon, Inc. Linker for linked fusion polypeptides
US5801029A (en) 1993-02-16 1998-09-01 Onyx Pharmaceuticals, Inc. Cytopathic viruses for therapy and prophylaxis of neoplasia
US5801005A (en) 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
GB9506466D0 (en) 1994-08-26 1995-05-17 Prolifix Ltd Cell cycle regulated repressor and dna element
WO1996040662A2 (en) 1995-06-07 1996-12-19 Cellpro, Incorporated Aminooxy-containing linker compounds and their application in conjugates
US5739169A (en) 1996-05-31 1998-04-14 Procept, Incorporated Aromatic compounds for inhibiting immune response
AU2003217912A1 (en) 2002-03-01 2003-09-16 Xencor Antibody optimization
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
EP3124497B1 (en) 2007-09-14 2020-04-15 Adimab, LLC Rationally designed, synthetic antibody libraries and uses therefor
KR102318383B1 (ko) 2010-07-16 2021-10-27 아디맵 엘엘씨 항체 라이브러리
CN111499755A (zh) * 2012-08-03 2020-08-07 丹娜法伯癌症研究院 抗-pd-l1和pd-l2双结合抗体单一试剂及其使用方法
SG11202009258RA (en) * 2018-03-23 2020-10-29 Univ Texas Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor
EP4501355A3 (en) * 2018-03-23 2025-04-30 Board Of Regents, The University Of Texas System Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor

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