JP2025512046A - タバコのアルカロイド含有量を調節する方法 - Google Patents

タバコのアルカロイド含有量を調節する方法 Download PDF

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Publication number
JP2025512046A
JP2025512046A JP2024560391A JP2024560391A JP2025512046A JP 2025512046 A JP2025512046 A JP 2025512046A JP 2024560391 A JP2024560391 A JP 2024560391A JP 2024560391 A JP2024560391 A JP 2024560391A JP 2025512046 A JP2025512046 A JP 2025512046A
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JP
Japan
Prior art keywords
plant
tobacco
seq
acid sequence
helix
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Pending
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JP2024560391A
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English (en)
Japanese (ja)
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JP2025512046A5 (https=
Inventor
カーレッド サラ ベン
デ アブレウ エ リマ フランシスコ アナスタシオ
ハビエル ガルドン－アルメロ
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Nicoventures Trading Ltd
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Nicoventures Trading Ltd
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Publication of JP2025512046A publication Critical patent/JP2025512046A/ja
Publication of JP2025512046A5 publication Critical patent/JP2025512046A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A01H1/10—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits
    • A01H1/101—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine or caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • A01H5/12—Leaves
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/82—Solanaceae, e.g. pepper, tobacco, potato, tomato or eggplant
    • A01H6/823—Nicotiana, e.g. tobacco
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Environmental Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2024560391A 2022-04-14 2023-04-13 タバコのアルカロイド含有量を調節する方法 Pending JP2025512046A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2205562.8A GB202205562D0 (en) 2022-04-14 2022-04-14 Method
GB2205562.8 2022-04-14
PCT/GB2023/050994 WO2023199065A1 (en) 2022-04-14 2023-04-13 Method of modulating the alkaloid content of tobacco

Publications (2)

Publication Number Publication Date
JP2025512046A true JP2025512046A (ja) 2025-04-16
JP2025512046A5 JP2025512046A5 (https=) 2025-04-23

Family

ID=81753281

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024560391A Pending JP2025512046A (ja) 2022-04-14 2023-04-13 タバコのアルカロイド含有量を調節する方法

Country Status (5)

Country Link
US (1) US20250230457A1 (https=)
EP (1) EP4507486A1 (https=)
JP (1) JP2025512046A (https=)
GB (1) GB202205562D0 (https=)
WO (1) WO2023199065A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008531038A (ja) * 2005-02-28 2008-08-14 国立大学法人 奈良先端科学技術大学院大学 植物におけるニコチン類縁アルカロイド量を低下させる方法
JP2020524508A (ja) * 2017-06-23 2020-08-20 ユニバーシティ オブ ケンタッキー リサーチ ファウンデーションＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｋｅｎｔｕｃｋｙ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ 方法
JP2021516055A (ja) * 2018-03-05 2021-07-01 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー 変化したアルカロイドレベルと望ましい葉品質とを有するタバコ植物およびタバコ製品を作製するための組成物および方法

Family Cites Families (17)

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US2162738A (en) 1937-08-18 1939-06-20 Clarence E Mccoy Extracting nicotine from tobacco
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
KR100225087B1 (ko) 1990-03-23 1999-10-15 한스 발터라벤 피타아제의 식물내 발현
GB9524350D0 (en) 1995-11-29 1996-01-31 Lynxvale Ltd Enhancer-increased gene expression in plants
ES2582091T3 (es) 2005-10-18 2016-09-09 Precision Biosciences Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas
US9102948B2 (en) 2006-11-17 2015-08-11 22Nd Century Limited, Llc Regulating alkaloids
EP2215223B1 (en) 2007-10-31 2013-05-01 Precision Biosciences, Inc. Rationally-designed single-chain meganucleases with non-palindromic recognition sequences
EP2206723A1 (en) 2009-01-12 2010-07-14 Bonas, Ulla Modular DNA-binding domains
US8953158B2 (en) 2009-09-04 2015-02-10 Danny S. Moshe Grading of agricultural products via hyper spectral imaging and analysis
WO2011072246A2 (en) 2009-12-10 2011-06-16 Regents Of The University Of Minnesota Tal effector-mediated dna modification
PL2753202T3 (pl) 2011-09-06 2016-11-30 Podgrzewanie materiału przeznaczonego do palenia
CA2890160A1 (en) 2012-10-31 2014-05-08 Cellectis Coupling herbicide resistance with targeted insertion of transgenes in plants
EP3031921B1 (en) 2012-12-12 2025-03-12 The Broad Institute, Inc. Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
GB2515502A (en) 2013-06-25 2014-12-31 British American Tobacco Co Apparatus and method
WO2018222667A1 (en) * 2017-05-31 2018-12-06 22Nd Century Limited, Llc Genome editing methods for producing low-nicotine tobacco products
GB201818715D0 (en) * 2018-11-16 2019-01-02 British American Tobacco Investments Ltd Method
CN111690661A (zh) * 2020-06-01 2020-09-22 云南省烟草农业科学研究院 一种烟草NtbHLH13基因突变体及分子鉴定方法和应用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008531038A (ja) * 2005-02-28 2008-08-14 国立大学法人 奈良先端科学技術大学院大学 植物におけるニコチン類縁アルカロイド量を低下させる方法
JP2020524508A (ja) * 2017-06-23 2020-08-20 ユニバーシティ オブ ケンタッキー リサーチ ファウンデーションＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｋｅｎｔｕｃｋｙ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ 方法
JP2021516055A (ja) * 2018-03-05 2021-07-01 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー 変化したアルカロイドレベルと望ましい葉品質とを有するタバコ植物およびタバコ製品を作製するための組成物および方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PLANTPHYSIOL., vol. 136(4), JPN7026000458, 2004, pages 3999 - 4009, ISSN: 0005833098 *
化学と生物, vol. 51(7), JPN6026004475, 2013, pages 445 - 447, ISSN: 0005833097 *

Also Published As

Publication number Publication date
WO2023199065A1 (en) 2023-10-19
GB202205562D0 (en) 2022-06-01
US20250230457A1 (en) 2025-07-17
EP4507486A1 (en) 2025-02-19

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