JP2025510915A - 産後うつ病の処置のための５－メトキシ－ｎ，ｎ－ジメチルトリプタミン - Google Patents

産後うつ病の処置のための５－メトキシ－ｎ，ｎ－ジメチルトリプタミン Download PDF

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Publication number
JP2025510915A
JP2025510915A JP2024557201A JP2024557201A JP2025510915A JP 2025510915 A JP2025510915 A JP 2025510915A JP 2024557201 A JP2024557201 A JP 2024557201A JP 2024557201 A JP2024557201 A JP 2024557201A JP 2025510915 A JP2025510915 A JP 2025510915A
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JP
Japan
Prior art keywords
dmt
meo
pharma
acceptable salt
score
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Pending
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JP2024557201A
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English (en)
Japanese (ja)
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JP2025510915A5 (enExample
Inventor
タイス・ターヴィ
コナー・バーク
ニーシャ・ガフニー
Original Assignee
ジーエイチ・リサーチ・アイルランド・リミテッド
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Priority claimed from PCT/EP2023/057874 external-priority patent/WO2023186827A1/en
Publication of JP2025510915A publication Critical patent/JP2025510915A/ja
Publication of JP2025510915A5 publication Critical patent/JP2025510915A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2024557201A 2022-03-27 2023-03-27 産後うつ病の処置のための５－メトキシ－ｎ，ｎ－ジメチルトリプタミン Pending JP2025510915A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP22000085 2022-03-27
EP22000084.8 2022-03-27
EP22000085.5 2022-03-27
EP22000084 2022-03-27
EP23154014.7 2023-01-30
EP23153996 2023-01-30
EP23154014 2023-01-30
EP23153996.6 2023-01-30
PCT/EP2023/057874 WO2023186827A1 (en) 2022-03-27 2023-03-27 5-methoxy-n,n-dimethyltryptamine for the treatment of postpartum depression

Publications (2)

Publication Number Publication Date
JP2025510915A true JP2025510915A (ja) 2025-04-15
JP2025510915A5 JP2025510915A5 (enExample) 2026-04-10

Family

ID=93292078

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024557201A Pending JP2025510915A (ja) 2022-03-27 2023-03-27 産後うつ病の処置のための５－メトキシ－ｎ，ｎ－ジメチルトリプタミン

Country Status (8)

Country Link
US (1) US20250205200A1 (enExample)
EP (1) EP4499080A1 (enExample)
JP (1) JP2025510915A (enExample)
KR (1) KR20240167886A (enExample)
CN (1) CN119156213A (enExample)
AU (1) AU2023242438A1 (enExample)
CA (1) CA3255671A1 (enExample)
IL (1) IL315894A (enExample)

Also Published As

Publication number Publication date
KR20240167886A (ko) 2024-11-28
AU2023242438A1 (en) 2024-11-07
EP4499080A1 (en) 2025-02-05
US20250205200A1 (en) 2025-06-26
CA3255671A1 (en) 2023-10-05
IL315894A (en) 2024-11-01
CN119156213A (zh) 2024-12-17

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