JP2025510901A5 - - Google Patents
Info
- Publication number
- JP2025510901A5 JP2025510901A5 JP2024557148A JP2024557148A JP2025510901A5 JP 2025510901 A5 JP2025510901 A5 JP 2025510901A5 JP 2024557148 A JP2024557148 A JP 2024557148A JP 2024557148 A JP2024557148 A JP 2024557148A JP 2025510901 A5 JP2025510901 A5 JP 2025510901A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- variant pro
- pro region
- amino acid
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263326615P | 2022-04-01 | 2022-04-01 | |
| US63/326,615 | 2022-04-01 | ||
| PCT/US2023/065162 WO2023192953A1 (en) | 2022-04-01 | 2023-03-30 | Pro-region mutations enhancing protein production in gram-positive bacterial cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025510901A JP2025510901A (ja) | 2025-04-15 |
| JP2025510901A5 true JP2025510901A5 (enExample) | 2026-03-13 |
Family
ID=86227005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024557148A Pending JP2025510901A (ja) | 2022-04-01 | 2023-03-30 | グラム陽性細菌細胞におけるタンパク質産生を強化するプロ領域突然変異 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250223623A1 (enExample) |
| EP (1) | EP4504756A1 (enExample) |
| JP (1) | JP2025510901A (enExample) |
| KR (1) | KR20240167690A (enExample) |
| CN (1) | CN119213015A (enExample) |
| WO (1) | WO2023192953A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2026030345A1 (en) * | 2024-07-29 | 2026-02-05 | Danisco Us Inc. | Signal and pro-region sequence variants for enhanced protease production in bacillus cells |
| WO2026050315A1 (en) | 2024-08-29 | 2026-03-05 | Danisco Us Inc. | Subtilisin variants and methods of use |
| WO2026136410A1 (en) | 2024-12-17 | 2026-06-25 | Danisco Us Inc. | Intracellular co-expression of protease inhibitor in bacillus improves cell viability and enhances protease production |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5429950A (en) | 1992-03-30 | 1995-07-04 | Genencor International, Inc. | Heterologous gene expression in bacillus subtilis: fusion approach |
| AU2001279254A1 (en) | 2000-08-11 | 2002-02-25 | Genencor International, Inc. | Bacillus transformation, transformants and mutant libraries |
| DK2339016T3 (da) | 2002-03-29 | 2017-01-23 | Danisco Us Inc | Øget produktion af subtilisiner |
| KR20090129425A (ko) | 2007-03-12 | 2009-12-16 | 다니스코 유에스 인크. | 개질된 프로테아제 |
| CA2759695C (en) * | 2009-04-24 | 2018-05-01 | Danisco Us Inc. | Proteases with modified pro regions |
| CA2989667A1 (en) | 2015-06-17 | 2016-12-22 | Danisco Us Inc. | Proteases with modified propeptide regions |
| JP7218985B2 (ja) | 2017-09-13 | 2023-02-07 | ダニスコ・ユーエス・インク | バチルス属（Ｂａｃｉｌｌｕｓ）におけるタンパク質産生の増加のための改変５’－非翻訳領域（ＵＴＲ）配列 |
-
2023
- 2023-03-30 EP EP23720024.1A patent/EP4504756A1/en active Pending
- 2023-03-30 WO PCT/US2023/065162 patent/WO2023192953A1/en not_active Ceased
- 2023-03-30 KR KR1020247035890A patent/KR20240167690A/ko active Pending
- 2023-03-30 JP JP2024557148A patent/JP2025510901A/ja active Pending
- 2023-03-30 CN CN202380040804.1A patent/CN119213015A/zh active Pending
- 2023-03-30 US US18/851,026 patent/US20250223623A1/en active Pending
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