JP2025510189A5 - - Google Patents

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Publication number
JP2025510189A5
JP2025510189A5 JP2024556559A JP2024556559A JP2025510189A5 JP 2025510189 A5 JP2025510189 A5 JP 2025510189A5 JP 2024556559 A JP2024556559 A JP 2024556559A JP 2024556559 A JP2024556559 A JP 2024556559A JP 2025510189 A5 JP2025510189 A5 JP 2025510189A5
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JP
Japan
Prior art keywords
seq
amino acid
sequence
chain variable
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024556559A
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English (en)
Japanese (ja)
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JP2025510189A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/064941 external-priority patent/WO2023183927A2/en
Publication of JP2025510189A publication Critical patent/JP2025510189A/ja
Publication of JP2025510189A5 publication Critical patent/JP2025510189A5/ja
Pending legal-status Critical Current

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JP2024556559A 2022-03-24 2023-03-24 ヒト化抗cd45抗体 Pending JP2025510189A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202263323257P 2022-03-24 2022-03-24
US63/323,257 2022-03-24
US202263405237P 2022-09-09 2022-09-09
US63/405,237 2022-09-09
US202263407979P 2022-09-19 2022-09-19
US63/407,979 2022-09-19
PCT/US2023/064941 WO2023183927A2 (en) 2022-03-24 2023-03-24 Humanized anti-cd45 antibodies

Publications (2)

Publication Number Publication Date
JP2025510189A JP2025510189A (ja) 2025-04-14
JP2025510189A5 true JP2025510189A5 (https=) 2026-04-01

Family

ID=88102093

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024556559A Pending JP2025510189A (ja) 2022-03-24 2023-03-24 ヒト化抗cd45抗体

Country Status (6)

Country Link
US (2) US11981741B2 (https=)
EP (1) EP4490197A4 (https=)
JP (1) JP2025510189A (https=)
CN (1) CN119256014A (https=)
CA (1) CA3246544A1 (https=)
WO (1) WO2023183927A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024279278A1 (en) 2023-05-31 2025-12-18 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
US20250127728A1 (en) 2023-10-05 2025-04-24 Capstan Therapeutics, Inc. Constrained Ionizable Cationic Lipids and Lipid Nanoparticles
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
US20250302763A1 (en) 2024-02-22 2025-10-02 Capstan Therapeutics, Inc. Immune engineering amplification
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles
CN118620078B (zh) * 2024-07-09 2024-11-19 武汉爱博泰克生物科技有限公司 抗人cd45ra蛋白的抗体、抗体偶联物及其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9029636B2 (en) * 2008-02-05 2015-05-12 Monsanto Technology Llc Isolated novel nucleic acid and protein molecules from soy and methods of using those molecules to generate transgenic plants with enhanced agronomic traits
CN104710504B (zh) 2009-07-22 2019-09-13 锕医药股份有限公司 用于制备放射性免疫缀合物的方法
JP6047142B2 (ja) * 2011-04-01 2016-12-21 ウニヴェルズィテート シュトゥットガルト 抗体結合ドメインを有する組換えtnfリガンドファミリーメンバーポリペプチドおよびそれらの使用
CA2861003C (en) * 2012-01-13 2023-03-28 Julius-Maximilians-Universitat Wurzburg Dual antigen-induced bipartite functional complementation
EP3297684B1 (en) 2015-05-21 2020-12-23 Actinium Pharmaceuticals, Inc. Infusion administration of conjugated monoclonal antibodies
GB201601073D0 (en) * 2016-01-20 2016-03-02 Ucb Biopharma Sprl Antibodies
WO2017155937A1 (en) 2016-03-07 2017-09-14 Actinium Pharmaceuticals, Inc. Stabilized radiolabeled anti-cd45 immunoglobulin compositions
JP2020530280A (ja) * 2017-07-03 2020-10-22 トルク セラピューティクス, インコーポレイテッド 免疫刺激性融合分子およびその使用
WO2019084273A1 (en) * 2017-10-25 2019-05-02 Actinium Pharmaceuticals, Inc. METHODS OF ANTI-CD45-BASED LYMPHODEPPLICATION AND USES THEREOF IN COMBINATION WITH ACT-BASED ANTICANCER THERAPIES
WO2020092655A1 (en) * 2018-10-30 2020-05-07 Magenta Therapeutics, Inc. Methods for allogeneic hematopoietic stem cell transplantation
WO2020132672A1 (en) * 2018-12-21 2020-06-25 Actinium Pharmaceuticals, Inc. Combination of radioimmunotherapy and immune checkpoint therapy in the treatment of cancer
WO2020159656A1 (en) 2019-02-01 2020-08-06 Actinium Pharmaceuticals, Inc. Molecules and their derivatives directed against cd45
JP7650819B2 (ja) 2019-04-24 2025-03-25 ブイオーアール バイオファーマ インコーポレーテッド 抗-cd45抗体薬物コンジュゲート及びその使用
CA3137908A1 (en) * 2019-04-25 2020-10-29 Actinium Pharmaceuticals, Inc. Compositions and methods of immunodepletion for the treatment of malignant and non-malignant hematological diseases
US12605472B2 (en) 2019-09-17 2026-04-21 Actinium Pharmaceuticals, Inc. Radiolabeling of anti-CD45 immunoglobulin and methods of use thereof
WO2022040577A1 (en) 2020-08-20 2022-02-24 City Of Hope Compositions and uses of cd45 targeted chimeric antigen receptor modified t cells

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