JP2025508127A - 眼薬物送達インサートを投与することによる加齢黄斑変性症の予防方法 - Google Patents

眼薬物送達インサートを投与することによる加齢黄斑変性症の予防方法 Download PDF

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Publication number
JP2025508127A
JP2025508127A JP2024553781A JP2024553781A JP2025508127A JP 2025508127 A JP2025508127 A JP 2025508127A JP 2024553781 A JP2024553781 A JP 2024553781A JP 2024553781 A JP2024553781 A JP 2024553781A JP 2025508127 A JP2025508127 A JP 2025508127A
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JP
Japan
Prior art keywords
insert
eye
day
days
borolanib
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Pending
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JP2024553781A
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English (en)
Japanese (ja)
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JP2025508127A5 (https=
Inventor
サイード サイム，
ジェイ エス． デューカー，
ダリオ パッジャリーノ，
ミッシェル ハワード‐スパークス，
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Eyepoint Pharmaceuticals Inc
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Eyepoint Pharmaceuticals Inc
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Application filed by Eyepoint Pharmaceuticals Inc filed Critical Eyepoint Pharmaceuticals Inc
Publication of JP2025508127A publication Critical patent/JP2025508127A/ja
Publication of JP2025508127A5 publication Critical patent/JP2025508127A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2024553781A 2022-03-11 2023-03-10 眼薬物送達インサートを投与することによる加齢黄斑変性症の予防方法 Pending JP2025508127A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263318822P 2022-03-11 2022-03-11
US63/318,822 2022-03-11
US202263390036P 2022-07-18 2022-07-18
US63/390,036 2022-07-18
PCT/US2023/064139 WO2023173088A1 (en) 2022-03-11 2023-03-10 Method of preventing age-related macular degeneration by administering an ocular drug delivery insert

Publications (2)

Publication Number Publication Date
JP2025508127A true JP2025508127A (ja) 2025-03-21
JP2025508127A5 JP2025508127A5 (https=) 2026-04-07

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ID=85873993

Family Applications (1)

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JP2024553781A Pending JP2025508127A (ja) 2022-03-11 2023-03-10 眼薬物送達インサートを投与することによる加齢黄斑変性症の予防方法

Country Status (9)

Country Link
US (1) US20250205152A1 (https=)
EP (1) EP4489749A1 (https=)
JP (1) JP2025508127A (https=)
KR (1) KR20250002220A (https=)
AU (1) AU2023230975A1 (https=)
CA (1) CA3245205A1 (https=)
IL (1) IL315331A (https=)
TW (1) TW202345803A (https=)
WO (1) WO2023173088A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3886946A1 (en) 2019-06-05 2021-10-06 Regeneron Pharmaceuticals, Inc. Devices and methods for precision dose delivery
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2565683T3 (es) 2006-09-15 2016-04-06 Xcovery, Inc. Compuestos inhibidores de quinasa
WO2018059556A1 (zh) 2016-09-29 2018-04-05 贝达药业股份有限公司 激酶抑制剂化合物的多晶型、含其的药物组合物及其制备方法和应用
EP4537830A3 (en) * 2017-06-13 2025-06-11 EyePoint Pharmaceuticals, Inc. Bioerodible drug delivery devices
AU2021340733A1 (en) * 2020-09-14 2023-05-18 EyePoint Pharmaceuticals, Inc. Bioerodible ocular drug delivery insert and therapeutic method

Also Published As

Publication number Publication date
US20250205152A1 (en) 2025-06-26
IL315331A (en) 2024-10-01
WO2023173088A1 (en) 2023-09-14
CA3245205A1 (en) 2023-09-14
AU2023230975A1 (en) 2024-09-19
TW202345803A (zh) 2023-12-01
EP4489749A1 (en) 2025-01-15
KR20250002220A (ko) 2025-01-07

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