JP2025508127A - 眼薬物送達インサートを投与することによる加齢黄斑変性症の予防方法 - Google Patents

眼薬物送達インサートを投与することによる加齢黄斑変性症の予防方法 Download PDF

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Publication number
JP2025508127A
JP2025508127A JP2024553781A JP2024553781A JP2025508127A JP 2025508127 A JP2025508127 A JP 2025508127A JP 2024553781 A JP2024553781 A JP 2024553781A JP 2024553781 A JP2024553781 A JP 2024553781A JP 2025508127 A JP2025508127 A JP 2025508127A
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JP
Japan
Prior art keywords
insert
eye
day
days
borolanib
Prior art date
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Pending
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JP2024553781A
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English (en)
Japanese (ja)
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JP2025508127A5 (enExample
Inventor
サイード サイム，
ジェイ エス． デューカー，
ダリオ パッジャリーノ，
ミッシェル ハワード‐スパークス，
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EyePoint Inc
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Eyepoint Pharmaceuticals Inc
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Application filed by Eyepoint Pharmaceuticals Inc filed Critical Eyepoint Pharmaceuticals Inc
Publication of JP2025508127A publication Critical patent/JP2025508127A/ja
Publication of JP2025508127A5 publication Critical patent/JP2025508127A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2024553781A 2022-03-11 2023-03-10 眼薬物送達インサートを投与することによる加齢黄斑変性症の予防方法 Pending JP2025508127A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263318822P 2022-03-11 2022-03-11
US63/318,822 2022-03-11
US202263390036P 2022-07-18 2022-07-18
US63/390,036 2022-07-18
PCT/US2023/064139 WO2023173088A1 (en) 2022-03-11 2023-03-10 Method of preventing age-related macular degeneration by administering an ocular drug delivery insert

Publications (2)

Publication Number Publication Date
JP2025508127A true JP2025508127A (ja) 2025-03-21
JP2025508127A5 JP2025508127A5 (enExample) 2026-04-07

Family

ID=85873993

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024553781A Pending JP2025508127A (ja) 2022-03-11 2023-03-10 眼薬物送達インサートを投与することによる加齢黄斑変性症の予防方法

Country Status (9)

Country Link
US (1) US20250205152A1 (enExample)
EP (1) EP4489749A1 (enExample)
JP (1) JP2025508127A (enExample)
KR (1) KR20250002220A (enExample)
AU (1) AU2023230975A1 (enExample)
CA (1) CA3245205A1 (enExample)
IL (1) IL315331A (enExample)
TW (1) TW202345803A (enExample)
WO (1) WO2023173088A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20240329A1 (es) 2019-06-05 2024-02-27 Regeneron Pharma Dispositivos y metodos para administracion de dosis de precision
US12649031B2 (en) 2021-09-08 2026-06-09 Regeneron Pharmaceuticals, Inc. Methods for delivering agents with pre-filled syringes to minimize intraocular inflammation
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008033562A2 (en) 2006-09-15 2008-03-20 Xcovery, Inc. Kinase inhibitor compounds
SG11201901962QA (en) 2016-09-29 2019-04-29 Equinox Sciences Llc Polymorphic form of kinase inhibitor compound, pharmaceutical composition containing same, and preparation method therefor and use thereof
CA3066437A1 (en) * 2017-06-13 2018-12-20 EyePoint Pharmaceuticals, Inc. Bioerodible drug delivery devices
SI4210682T1 (sl) * 2020-09-14 2026-07-31 EyePoint, Inc. Bioerozibilni očesni vložek za dovajanje zdravil in terapevtska metoda

Also Published As

Publication number Publication date
TW202345803A (zh) 2023-12-01
IL315331A (en) 2024-10-01
KR20250002220A (ko) 2025-01-07
EP4489749A1 (en) 2025-01-15
US20250205152A1 (en) 2025-06-26
CA3245205A1 (en) 2023-09-14
WO2023173088A1 (en) 2023-09-14
AU2023230975A1 (en) 2024-09-19

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