JP2025505261A - 統合失調症患者における再発の予防におけるロルペリドンの使用 - Google Patents

統合失調症患者における再発の予防におけるロルペリドンの使用 Download PDF

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JP2025505261A
JP2025505261A JP2024547680A JP2024547680A JP2025505261A JP 2025505261 A JP2025505261 A JP 2025505261A JP 2024547680 A JP2024547680 A JP 2024547680A JP 2024547680 A JP2024547680 A JP 2024547680A JP 2025505261 A JP2025505261 A JP 2025505261A
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patient
schizophrenia
lorperidone
symptoms
months
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JP2025505261A5 (https=
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ラスリンガー,レミー
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ミネルヴァ ニューロサイエンシズ,インコーポレーテッド
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Publication of JP2025505261A publication Critical patent/JP2025505261A/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2024547680A 2022-02-14 2023-02-13 統合失調症患者における再発の予防におけるロルペリドンの使用 Pending JP2025505261A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263309874P 2022-02-14 2022-02-14
US63/309,874 2022-02-14
PCT/US2023/062500 WO2023154927A1 (en) 2022-02-14 2023-02-13 Use of roluperidone in preventing relapse in schizophrenia patients

Publications (2)

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JP2025505261A true JP2025505261A (ja) 2025-02-21
JP2025505261A5 JP2025505261A5 (https=) 2026-02-20

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ID=85569991

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JP2024547680A Pending JP2025505261A (ja) 2022-02-14 2023-02-13 統合失調症患者における再発の予防におけるロルペリドンの使用

Country Status (12)

Country Link
US (1) US20230255953A1 (https=)
EP (2) EP4479049B1 (https=)
JP (1) JP2025505261A (https=)
KR (1) KR20240161650A (https=)
CN (1) CN118984705A (https=)
AU (1) AU2023217097A1 (https=)
CA (1) CA3243767A1 (https=)
CL (1) CL2024002418A1 (https=)
ES (1) ES3064313T3 (https=)
IL (1) IL314859A (https=)
MX (1) MX2024009828A (https=)
WO (1) WO2023154927A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL319156A (en) 2017-06-21 2025-04-01 Minerva Neurosciences Inc Controlled-release oral dosage forms are resistant to gastric acid.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7166617B2 (en) 2000-02-29 2007-01-23 Mitsubishi Pharma Corporation Cyclic amide derivatives
PL3227273T3 (pl) 2014-12-02 2022-05-30 Minerva Neurosciences, Inc. Kompozycje zawierające 2-((1-(2-(4-fluorofenylo)-2-oksoetylo)piperydyn-4-ylo)metylo)izoindolin-1-on do leczenia schizofrenii
IL319156A (en) 2017-06-21 2025-04-01 Minerva Neurosciences Inc Controlled-release oral dosage forms are resistant to gastric acid.
WO2020264486A1 (en) * 2019-06-28 2020-12-30 Teva Czech Industries S.R.O Solid state forms of roluperidone and salts thereof

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Publication number Publication date
CA3243767A1 (en) 2023-08-17
WO2023154927A1 (en) 2023-08-17
EP4479049B1 (en) 2025-12-17
US20230255953A1 (en) 2023-08-17
EP4729122A2 (en) 2026-04-22
IL314859A (en) 2024-10-01
AU2023217097A1 (en) 2024-08-29
CL2024002418A1 (es) 2024-12-13
EP4479049A1 (en) 2024-12-25
CN118984705A (zh) 2024-11-19
ES3064313T3 (en) 2026-04-23
MX2024009828A (es) 2024-11-08
KR20240161650A (ko) 2024-11-12

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