JP2025504386A - 抗菌剤を含む涙小管内挿入物 - Google Patents

抗菌剤を含む涙小管内挿入物 Download PDF

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Publication number
JP2025504386A
JP2025504386A JP2024541023A JP2024541023A JP2025504386A JP 2025504386 A JP2025504386 A JP 2025504386A JP 2024541023 A JP2024541023 A JP 2024541023A JP 2024541023 A JP2024541023 A JP 2024541023A JP 2025504386 A JP2025504386 A JP 2025504386A
Authority
JP
Japan
Prior art keywords
insert
sustained release
besifloxacin
release biodegradable
biodegradable intraocular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024541023A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025504386A5 (cg-RX-API-DMAC7.html
Inventor
ブリザード，チャールズ，ディー．
デサイ，アンキタ
ゴールドステイン，マイケル
プリエム，ミーガン
Original Assignee
オキュラ セラピューティクス，インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オキュラ セラピューティクス，インコーポレイテッド filed Critical オキュラ セラピューティクス，インコーポレイテッド
Publication of JP2025504386A publication Critical patent/JP2025504386A/ja
Publication of JP2025504386A5 publication Critical patent/JP2025504386A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2024541023A 2022-01-09 2023-01-06 抗菌剤を含む涙小管内挿入物 Pending JP2025504386A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263297778P 2022-01-09 2022-01-09
US63/297,778 2022-01-09
PCT/US2023/010321 WO2023133278A1 (en) 2022-01-09 2023-01-06 Intracanalicular insert comprising an antimicrobial agent

Publications (2)

Publication Number Publication Date
JP2025504386A true JP2025504386A (ja) 2025-02-12
JP2025504386A5 JP2025504386A5 (cg-RX-API-DMAC7.html) 2026-01-14

Family

ID=87074150

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024541023A Pending JP2025504386A (ja) 2022-01-09 2023-01-06 抗菌剤を含む涙小管内挿入物

Country Status (6)

Country Link
US (1) US20250114373A1 (cg-RX-API-DMAC7.html)
EP (1) EP4460286A4 (cg-RX-API-DMAC7.html)
JP (1) JP2025504386A (cg-RX-API-DMAC7.html)
CN (1) CN118804742A (cg-RX-API-DMAC7.html)
CA (1) CA3246246A1 (cg-RX-API-DMAC7.html)
WO (1) WO2023133278A1 (cg-RX-API-DMAC7.html)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8415342B2 (en) * 2008-10-29 2013-04-09 Bausch & Lomb Incorporated Besifloxacin ophthalmic composition for the treatment or control of infection
EP4279064A3 (en) * 2015-05-12 2024-02-28 Incept, LLC Drug delivery from hydrogels
AU2020262932B2 (en) * 2019-04-25 2025-11-13 Ocular Therapeutix, Inc. Intracanalicular hydrogel inserts for the delivery of anesthetics
PT3884929T (pt) * 2020-03-25 2023-08-09 Ocular Therapeutix Inc Implante ocular contendo um inibidor da tirosina cinase
EP4216929A1 (en) * 2020-09-24 2023-08-02 Ocular Therapeutix, Inc. Sustained release biodegradable intracanalicular inserts comprising a hydrogel and an active agent

Also Published As

Publication number Publication date
CN118804742A (zh) 2024-10-18
CA3246246A1 (en) 2023-07-13
EP4460286A4 (en) 2025-12-31
EP4460286A1 (en) 2024-11-13
WO2023133278A1 (en) 2023-07-13
US20250114373A1 (en) 2025-04-10

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